Health and Me

Ishita Roy

Oprah Winfrey Shares Her Fitness Journey While Being On GLP-1 Weight-loss Drugs

“I would have been thinking, ‘How many calories in that croissant? How long is it going to take me to work it off? If I have the croissant, I won’t be able to have dinner.’ I’d still be thinking about that damn croissant!” This morning, however, she is blissfully unbothered: “I felt nothing. The only thing I thought was, ‘I need to clean up these crumbs.’ ” These are the thoughts that would come to <span>Oprah Winfrey</span>'s mind whenever she would try to eat something butter, she shared in an interview with PEOPLE. However, now, she can eat a croissant, like a croissant, without being obsessed about it for an entire day. “I’ve just had a croissant. And I ate the full thing,” she said describing her breakfast. 

Winfrey started taking GLP-1 weight-loss jabs two and a half years ago, when she thought that she suffers from obesity and she cannot fight it without help. “I thought it was about discipline and willpower. But I stopped blaming myself,” said Winfrey.

These medications transformed the way she looked at life. As she soon turns 72 on January 29, she no longer sees exercise as a punishment. She said she could be happily "side-planking and deadlifting." She now no longer drinks alcohol. “I could outdrink everyone at the table,” she notes with a laugh) and is amazed that she’s satisfied after she eats. “I’m not constantly punishing myself,” she says. “I hardly recognize the woman I’ve become. But she’s a happy woman.” She told PEOPLE. 

Winfrey's weight has always been a struggle for her, especially when she read painful headlines like 'Oprah - Fatter Than Ever' or 'Oprah Warned: 'Diet or Die''. In fact, in her first appearance on The Tonight Show in 1985, she was goaded into agreeing to lose 15 lbs. by hot Joan Rivers. While she became the one-name star, she always remained aware about her weight. “I’ve always been confident in whatever I was doing, but I was at the same time disappointed in my overweight body. “Was I embarrassed by it? Yes. Was I disappointed in myself for continuing to fail? Yes, every single time. I felt it was my fault,” she writes in her book, co-authored by obesity expert Dr Ania M Jastreboff:<em> Enough: Your Health, Your Weight and What It's Like to Be Free</em>. 

She wrote that she “felt doubly shameful because I have access to so much: chefs and trainers and the healthiest of foods.”

For decades, Oprah Winfrey lived under a microscope, her body turning into both public spectacle and personal battleground. She now openly admits that while she endured relentless humiliation, she also helped normalize weight shaming herself. In 1988, she survived four months on liquid shakes alone, famously dragging a wagon filled with 67 pounds of fat onto her show to prove she could fit into size 10 jeans. Years later, she lost 20 pounds simply because Vogue suggested it before a cover shoot. At the time, it felt like willpower. In hindsight, it felt like survival.

No diet or discipline seemed to last. No matter how hard she tried, her weight kept returning to 211 pounds, what experts now call a biological “set point.” Even after knee surgery in 2021, daily hikes and eating one meal a day, her body resisted. Ten-mile hikes still resulted in weight gain. The message was clear: this was not a motivation problem.

<h2>How Did GLP-1 Medication Transform Oprah Winfrey?</h2>

Everything shifted in 2023 when Winfrey hosted a special on obesity and had what she calls an epiphany. She finally understood obesity as a disease, not a personal failure. That realization cracked years of shame. GLP-1 medications, which she had earlier dismissed, suddenly felt like a medical tool rather than a moral shortcut. Starting the injections felt like relief, even a gift.

She briefly stopped the medication in early 2024, believing lifestyle changes alone might be enough. The weight returned. That’s when she accepted the truth: this would be lifelong care, not a phase. Now, she describes GLP-1 as a way to quiet the constant mental chatter around food. The “food noise” faded, replaced by calm, strength, and clarity.

Today, it’s not about a number on the scale. It’s about peace. Better health markers. Deeper relationships. Even unexpected changes, like losing interest in alcohol. Winfrey’s message is simple but radical: if obesity runs in your genes, it’s not your fault. And you deserve compassion, information, and real choices.

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“I would have been thinking, ‘How many calories in that croissant? How long is it going to take me to work it off? If I have the croissant, I won’t be able to have dinner.’ I’d still be thinking about that damn croissant!” This morning, however, she is blissfully unbothered: “I felt nothing. The only thing I thought was, ‘I need to clean up these crumbs.’ ” These are the thoughts that would come to Oprah Winfrey's mind whenever she would try to eat something butter, she shared in an interview with PEOPLE. However, now, she can eat a croissant, like a croissant, without being obsessed about it for an entire day. “I’ve just had a croissant. And I ate the full thing,” she said describing her breakfast. Winfrey started taking GLP-1 weight-loss jabs two and a half years ago, when she thought that she suffers from obesity and she cannot fight it without help. “I thought it was about discipline and willpower. But I stopped blaming myself,” said Winfrey.From Diet Culture to Self-BlameThese medications transformed the way she looked at life. As she soon turns 72 on January 29, she no longer sees exercise as a punishment. She said she could be happily "side-planking and deadlifting." She now no longer drinks alcohol. “I could outdrink everyone at the table,” she notes with a laugh) and is amazed that she’s satisfied after she eats. “I’m not constantly punishing myself,” she says. “I hardly recognize the woman I’ve become. But she’s a happy woman.” She told PEOPLE. Winfrey's weight has always been a struggle for her, especially when she read painful headlines like 'Oprah - Fatter Than Ever' or 'Oprah Warned: 'Diet or Die''. In fact, in her first appearance on The Tonight Show in 1985, she was goaded into agreeing to lose 15 lbs. by hot Joan Rivers. While she became the one-name star, she always remained aware about her weight. “I’ve always been confident in whatever I was doing, but I was at the same time disappointed in my overweight body. “Was I embarrassed by it? Yes. Was I disappointed in myself for continuing to fail? Yes, every single time. I felt it was my fault,” she writes in her book, co-authored by obesity expert Dr Ania M Jastreboff: Enough: Your Health, Your Weight and What It's Like to Be Free. She wrote that she “felt doubly shameful because I have access to so much: chefs and trainers and the healthiest of foods.”For decades, Oprah Winfrey lived under a microscope, her body turning into both public spectacle and personal battleground. She now openly admits that while she endured relentless humiliation, she also helped normalize weight shaming herself. In 1988, she survived four months on liquid shakes alone, famously dragging a wagon filled with 67 pounds of fat onto her show to prove she could fit into size 10 jeans. Years later, she lost 20 pounds simply because Vogue suggested it before a cover shoot. At the time, it felt like willpower. In hindsight, it felt like survival.When the Body Pushes BackNo diet or discipline seemed to last. No matter how hard she tried, her weight kept returning to 211 pounds, what experts now call a biological “set point.” Even after knee surgery in 2021, daily hikes and eating one meal a day, her body resisted. Ten-mile hikes still resulted in weight gain. The message was clear: this was not a motivation problem.How Did GLP-1 Medication Transform Oprah Winfrey?Everything shifted in 2023 when Winfrey hosted a special on obesity and had what she calls an epiphany. She finally understood obesity as a disease, not a personal failure. That realization cracked years of shame. GLP-1 medications, which she had earlier dismissed, suddenly felt like a medical tool rather than a moral shortcut. Starting the injections felt like relief, even a gift.She briefly stopped the medication in early 2024, believing lifestyle changes alone might be enough. The weight returned. That’s when she accepted the truth: this would be lifelong care, not a phase. Now, she describes GLP-1 as a way to quiet the constant mental chatter around food. The “food noise” faded, replaced by calm, strength, and clarity.Today, it’s not about a number on the scale. It’s about peace. Better health markers. Deeper relationships. Even unexpected changes, like losing interest in alcohol. Winfrey’s message is simple but radical: if obesity runs in your genes, it’s not your fault. And you deserve compassion, information, and real choices.