Health and Me

Rachel V Thomas

1,370 Mpox Cases, 7 Deaths Reported In July: WHO Says Risk Remains Moderate

A total of 1,370 <span><a href="https://www.healthandme.com/health/mpox">mpox</a></span> cases and seven deaths were reported globally in July, according to the World Health Organization (WHO), which continues to assess the global public health risk from the multi-country outbreak as moderate.

The WHO external situation report, published today, is based on data from 32 countries across four WHO regions. The case fatality ratio (CFR) was 0.5%.

About three-quarters of the cases were reported in the WHO African Region.

<h2>Madagascar Reports Highest Cases</h2>

Madagascar reported the highest number of cases, with 703 cases and seven deaths, followed by Angola (138), China (88), the Democratic Republic of the Congo (85) and Kenya (55).

Between July 6 and August 16, Madagascar reported 785 cases, while deaths remained at seven. Angola reported 184 cases, Kenya 94, the Democratic Republic of the Congo 41 and Cameroon 28.

The WHO noted that Congo's figures may be affected by delays in mpox reporting as the country focuses on its response to the Bundibugyo virus disease outbreak.

<h2>65,784 Mpox Cases Reported Since January 2025</h2>

From January 1, 2025, to July 31, 2026, a total of 65,784 mpox cases and 264 deaths were reported across 105 countries.

“WHO conducted a global mpox rapid risk assessment in August 2026; the overall global public health risk associated with the mpox multi-country outbreak was again assessed as moderate,” the WHO said.

“WHO continues to consider the ongoing multi-country mpox outbreak a graded emergency, with new outbreaks reported in multiple countries and over a thousand confirmed cases reported every month,” it added.

The WHO urged countries and partners to maintain mpox surveillance, notification and coordinated preparedness and response activities.

The WHO Director-General's standing recommendations on mpox have been extended until August 2027.

<h2><span rel="noindex">Clade Ib <a href="https://www.healthandme.com/health/mpox">Mpox</a> Spreads</span></h2>

Mpox transmission continues to affect key populations, largely through sexual transmission, followed by household spread and community outbreaks. All clades of monkeypox virus (MPXV) continue to circulate.

In July, the African Region reported more confirmed cases than in June, while the Americas, Western Pacific, European and South-East Asia regions reported fewer cases. The Eastern Mediterranean Region reported no confirmed cases.

Eleven African countries reported active transmission between July 6 and August 16, with 1,153 confirmed cases and seven deaths.

Chile and Hungary reported clade <span>Ib MPXV</span> for the first time. Several European countries, including the UK, have reported community transmission of clade Ib.

<h2><span rel="noindex">Mpox Vaccine</span> Shows Promising Early Results</h2>

The first human trial of <span>BNT166a</span>, an mRNA-based mpox vaccine developed by <span>BioNTech</span>, showed encouraging early results.

The vaccine was generally safe and well tolerated and triggered strong antibody responses across all dose levels, including in people who had and had not previously received vaccination against related viruses.

The trial involved 64 adults and was primarily designed to assess safety and immune responses, rather than whether the vaccine prevents infection.

“These findings are an important step forward in the development of a new generation of vaccines against mpox. We’ve shown that this mRNA vaccine approach can safely generate strong immune responses in people, which is very encouraging," said Professor Saul Faust, UK Chief Investigator for the trial.

The vaccine is now progressing to a larger trial to assess its effectiveness in real-world settings.

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A total of 1,370 mpox cases and seven deaths were reported globally in July, according to the World Health Organization (WHO), which continues to assess the global public health risk from the multi-country outbreak as moderate.The WHO external situation report, published today, is based on data from 32 countries across four WHO regions. The case fatality ratio (CFR) was 0.5%.About three-quarters of the cases were reported in the WHO African Region.Madagascar Reports Highest CasesMadagascar reported the highest number of cases, with 703 cases and seven deaths, followed by Angola (138), China (88), the Democratic Republic of the Congo (85) and Kenya (55).Between July 6 and August 16, Madagascar reported 785 cases, while deaths remained at seven. Angola reported 184 cases, Kenya 94, the Democratic Republic of the Congo 41 and Cameroon 28.The WHO noted that Congo's figures may be affected by delays in mpox reporting as the country focuses on its response to the Bundibugyo virus disease outbreak.65,784 Mpox Cases Reported Since January 2025From January 1, 2025, to July 31, 2026, a total of 65,784 mpox cases and 264 deaths were reported across 105 countries.“WHO conducted a global mpox rapid risk assessment in August 2026; the overall global public health risk associated with the mpox multi-country outbreak was again assessed as moderate,” the WHO said.“WHO continues to consider the ongoing multi-country mpox outbreak a graded emergency, with new outbreaks reported in multiple countries and over a thousand confirmed cases reported every month,” it added.The WHO urged countries and partners to maintain mpox surveillance, notification and coordinated preparedness and response activities.The WHO Director-General's standing recommendations on mpox have been extended until August 2027.Clade Ib Mpox SpreadsMpox transmission continues to affect key populations, largely through sexual transmission, followed by household spread and community outbreaks. All clades of monkeypox virus (MPXV) continue to circulate.In July, the African Region reported more confirmed cases than in June, while the Americas, Western Pacific, European and South-East Asia regions reported fewer cases. The Eastern Mediterranean Region reported no confirmed cases.Eleven African countries reported active transmission between July 6 and August 16, with 1,153 confirmed cases and seven deaths.Chile and Hungary reported clade Ib MPXV for the first time. Several European countries, including the UK, have reported community transmission of clade Ib.Mpox Vaccine Shows Promising Early ResultsThe first human trial of BNT166a, an mRNA-based mpox vaccine developed by BioNTech, showed encouraging early results.The vaccine was generally safe and well tolerated and triggered strong antibody responses across all dose levels, including in people who had and had not previously received vaccination against related viruses.The trial involved 64 adults and was primarily designed to assess safety and immune responses, rather than whether the vaccine prevents infection.“These findings are an important step forward in the development of a new generation of vaccines against mpox. We’ve shown that this mRNA vaccine approach can safely generate strong immune responses in people, which is very encouraging," said Professor Saul Faust, UK Chief Investigator for the trial.The vaccine is now progressing to a larger trial to assess its effectiveness in real-world settings.

1,370 mpox cases, 7 deaths reported in july: who says risk remains moderate

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