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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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A widespread listeria outbreak traced to contaminated ready-to-eat meals has resulted in at least six deaths and 27 hospitalizations across 18 states, according to the Centers for Disease Control and Prevention (CDC).
The Food and Drug Administration (FDA) has advised consumers to inspect their freezers for potentially affected items tied to the ongoing infections.
Nate’s Fine Foods, the company behind the products connected to the outbreak, issued a statement on September 29 confirming that listeria was found in some of its food products.
Listeria Outbreak Expands Across States, Linked to Ready-to-Eat Pasta Products
The number of deaths has increased in the ongoing listeria outbreak connected to ready-to-eat pasta dishes sold at major retailers including Walmart, Kroger, and Trader Joe’s.
According to the Food and Drug Administration (FDA), seven new cases of listeria infection have been confirmed in three additional states since the previous update on September 25. The outbreak has now affected 27 people across 18 states and caused six deaths as of October 30.
Of those infected, 25 required hospitalization, and one case involved a pregnancy-related loss, the FDA noted. The FDA, along with the U.S. Department of Agriculture (USDA) and the Centers for Disease Control and Prevention (CDC), continues to investigate the nationwide outbreak.
The investigation, which began in June, has traced the outbreak to contaminated precooked pasta produced by Nate’s Fine Foods, Inc. The tainted pasta was used in a variety of ready-to-eat items, including pasta salads, frozen meals, and deli products distributed through several major grocery chains.
Listeria is a harmful bacterium that causes listeriosis, a serious infection spread through contaminated food. It is commonly found in soil, water, and various ready-to-eat items such as deli meats, soft cheeses, and prepackaged meals like the recently recalled pasta sold at Walmart.
Unlike most bacteria, Listeria can survive and multiply in cold environments, including refrigerators, which is why safe food storage and thorough cooking are essential, according to the Centers for Disease Control and Prevention (CDC).
Although anyone can become infected, certain people face a greater risk of complications. These include pregnant women, newborns, older adults, and individuals with weakened immune systems. In pregnant women, the infection can lead to miscarriage, stillbirth, or severe illness in newborns.
Symptoms of listeriosis usually appear within two weeks of eating contaminated food. The illness often starts with digestive discomfort, including nausea or diarrhea, and can progress to more severe signs such as fever, muscle aches, headaches, stiff neck, confusion, and loss of balance.
According to The Associated Press, the following ready-to-eat meals have been recalled due to potential Listeria contamination:
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Donald Trump Health: Trump visited Walter Reed National Military Medical Center on October 10 for what he described as his “semi-annual physical.” He had already undergone a routine check-up in April. Speaking to reporters aboard Air Force One on his way to Japan, Trump confirmed that he received an MRI during his appointment.
“I did, I got an MRI—it was perfect,” Trump said, adding that reporters would need to ask his doctors for the reason behind it. “I think they gave you very conclusive reports. Nobody has ever given reports like I did. And if I didn’t think it would be good, I wouldn’t run. The doctor said they were some of the best results for someone my age.”
MRI stands for magnetic resonance imaging. It produces detailed scans of internal soft tissues and is commonly used for examining organs and detecting abnormalities.
He returned to Walter Reed on October 10 for “advanced imaging, laboratory tests, and preventive evaluations.” During the same visit, Trump also received his flu and COVID-19 booster vaccinations. Barbabella later stated that the former president remains in “excellent overall health.”
Earlier this year, the White House disclosed that Trump has chronic venous insufficiency (CVI), a common vascular disorder in which leg veins struggle to return blood to the heart properly. This condition can cause swelling and discomfort in the legs.
On October 10, Trump made another trip to Walter Reed National Military Medical Center. His spokesperson, Karoline Leavitt, described it as a “routine annual check-up,” even though it was his second visit to the facility in just six months. Dr. Sean Barbabella, the White House physician, did not provide details about the imaging or preventive evaluations carried out during the appointment. However, he stated that Trump’s lab results were “exceptional” and that his cardiac health appeared to be roughly 14 years younger than his actual age.
On October 27, Trump mentioned that he had undergone an undisclosed MRI scan during a previous visit to Walter Reed. Though he said the test produced “some of the best reports for the age” and “some of the best reports they’ve ever seen,” the lack of details surrounding the procedure has fueled speculation about his health.
Trump has also previously spoken about taking the Montreal Cognitive Assessment (MoCA), a test used to detect cognitive decline, but has repeatedly described it as a “very difficult IQ test.” It is not known whether another MoCA test was conducted during his October visit or if Trump was referring to the tests he took in April 2025 or January 2018.
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A wide range of people in the UK may be eligible for a free flu vaccine this season after the NHS confirmed that infections are increasing “earlier than usual.” Each year, the NHS provides flu vaccinations throughout autumn and early winter, as this is when flu activity tends to peak. Although influenza is typically mild for most people and symptoms clear up within a few weeks, some individuals face a much higher risk of serious complications and therefore need extra protection.
To ensure those at greatest risk are shielded from severe illness, the flu jab is offered free of charge to certain groups.
According to NHS England on X (formerly Twitter): “Flu cases have arrived earlier than usual and are already three times higher than this point last year, with infections climbing fastest among children. So far, NHS teams have administered 12.2 million flu vaccines to help safeguard the most vulnerable.”
The flu vaccine trains your immune system to recognise and fight the influenza virus without needing to be infected first. It contains a small, inactive portion of the flu virus, which triggers your body’s natural defences to produce antibodies.
After receiving the jab, it takes around ten days for protection to fully develop. Importantly, the vaccine cannot cause the flu, as the virus it contains is inactive. Most people only need one dose each year to stay protected through the season.
As per current NHS guidelines, six main groups of people can receive the flu jab at no cost. You qualify for a free vaccination if you are at higher risk or live with someone who may be.
Those eligible include:
If you qualify, you can receive the free vaccine in several convenient ways. You may book an appointment through your GP practice, or if you are aged 18 or over, you can arrange one online or through the NHS App at a participating pharmacy.
Many pharmacies also allow eligible individuals to walk in for the jab without a prior appointment, making it easier for those who need protection to get vaccinated quickly and safely.
However, not every pharmacy is part of the free flu vaccination programme. You can check which nearby pharmacies offer the service through the NHS website’s locator tool. The site also provides complete details about the flu vaccine, including information on its ingredients and how it works.
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