Health and Me

Itisha Arya

MIT Scientists Create ‘Smart Pill’ That Signals After Being Swallowed: What You Need To Know

mit scientist pill

A newly developed “smart pill” that can confirm whether a medication has actually been swallowed could one day change how doctors track prescription use. Created by researchers at <span>MIT</span> along with partner institutions, the technology was described in a study published in Nature Communications. These electronic capsules are designed to send out a wireless signal once ingested and then safely dissolve inside the stomach over the course of about a week.

While the idea sounds straightforward, the implications are significant. Research shows that nearly half of Americans living with chronic illnesses do not take long-term medications exactly as prescribed. Below is what you need to know about how this smart pill works and why it matters.

<h2>What Is The New Smart Pill Designed By MIT Researchers?</h2>

In a development aimed at improving medication adherence, engineers at MIT have created a pill that can confirm when it has been swallowed. The reporting mechanism can be built into standard pill capsules and includes a biodegradable radio frequency antenna. After transmitting a signal to confirm ingestion, most of the pill’s components dissolve in the stomach. A tiny radio frequency chip then passes naturally through the digestive system and exits the body.

According to MIT News, researchers believe this technology could be particularly helpful for transplant recipients who rely on immunosuppressive drugs, as well as patients being treated long term for infections such as HIV or tuberculosis.

“The idea is to make sure this helps people receive the treatment they need so they can achieve the best possible health outcomes,” Giovanni Traverso, associate professor of medical engineering and senior author of the study, told MIT News.

<h2>The New Smart Pill Can Communicate</h2>

Not taking medication as prescribed remains a major public health problem, contributing to hundreds of thousands of avoidable deaths and adding billions of dollars to healthcare costs every year. To address this, Traverso’s team has previously developed capsules that can stay in the digestive system for days or even weeks, releasing medicine at scheduled intervals. However, not every drug can be delivered in this way.

“We know that systems designed to stay in the body longer can improve adherence,” Traverso explained. “But for some medications, altering the pill isn’t an option. So the question is what else we can do to support patients and help healthcare providers ensure medications are actually being taken.”

In this latest study, the researchers shifted their focus toward better tracking of medication use. They turned to radio frequency technology, which is safe for humans and easy to detect from outside the body. This allowed them to design a capsule that sends a signal once it has been swallowed, giving doctors a clearer picture of whether patients are taking their medicine.

<h2>The Smart Pill Will Be Using Radio Frequency</h2>

The capsule is designed to keep its signal blocked until it reaches the stomach. After ingestion, stomach fluids dissolve the outer coating, activating the radio frequency signal that confirms the pill has been swallowed. The remaining materials then break down safely inside the body.

To test the system, researchers conducted experiments in pigs, whose digestive systems are similar to those of humans. The study found that the capsules consistently transmitted signals after ingestion and dissolved without leaving behind harmful chemical residue, according to MIT News.

Looking ahead, researchers told the New York Post that they hope to develop a wearable device for humans that could receive the signal and automatically share the information with healthcare providers. Still, widespread use is not imminent. Despite encouraging early findings, the smart pills will need thorough testing in human trials to confirm both safety and effectiveness before they can receive approval.

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A newly developed “smart pill” that can confirm whether a medication has actually been swallowed could one day change how doctors track prescription use. Created by researchers at MIT along with partner institutions, the technology was described in a study published in Nature Communications. These electronic capsules are designed to send out a wireless signal once ingested and then safely dissolve inside the stomach over the course of about a week.While the idea sounds straightforward, the implications are significant. Research shows that nearly half of Americans living with chronic illnesses do not take long-term medications exactly as prescribed. Below is what you need to know about how this smart pill works and why it matters.What Is The New Smart Pill Designed By MIT Researchers?In a development aimed at improving medication adherence, engineers at MIT have created a pill that can confirm when it has been swallowed. The reporting mechanism can be built into standard pill capsules and includes a biodegradable radio frequency antenna. After transmitting a signal to confirm ingestion, most of the pill’s components dissolve in the stomach. A tiny radio frequency chip then passes naturally through the digestive system and exits the body.According to MIT News, researchers believe this technology could be particularly helpful for transplant recipients who rely on immunosuppressive drugs, as well as patients being treated long term for infections such as HIV or tuberculosis.“The idea is to make sure this helps people receive the treatment they need so they can achieve the best possible health outcomes,” Giovanni Traverso, associate professor of medical engineering and senior author of the study, told MIT News.The New Smart Pill Can CommunicateNot taking medication as prescribed remains a major public health problem, contributing to hundreds of thousands of avoidable deaths and adding billions of dollars to healthcare costs every year. To address this, Traverso’s team has previously developed capsules that can stay in the digestive system for days or even weeks, releasing medicine at scheduled intervals. However, not every drug can be delivered in this way.“We know that systems designed to stay in the body longer can improve adherence,” Traverso explained. “But for some medications, altering the pill isn’t an option. So the question is what else we can do to support patients and help healthcare providers ensure medications are actually being taken.”In this latest study, the researchers shifted their focus toward better tracking of medication use. They turned to radio frequency technology, which is safe for humans and easy to detect from outside the body. This allowed them to design a capsule that sends a signal once it has been swallowed, giving doctors a clearer picture of whether patients are taking their medicine.The Smart Pill Will Be Using Radio FrequencyThe capsule is designed to keep its signal blocked until it reaches the stomach. After ingestion, stomach fluids dissolve the outer coating, activating the radio frequency signal that confirms the pill has been swallowed. The remaining materials then break down safely inside the body.To test the system, researchers conducted experiments in pigs, whose digestive systems are similar to those of humans. The study found that the capsules consistently transmitted signals after ingestion and dissolved without leaving behind harmful chemical residue, according to MIT News.Looking ahead, researchers told the New York Post that they hope to develop a wearable device for humans that could receive the signal and automatically share the information with healthcare providers. Still, widespread use is not imminent. Despite encouraging early findings, the smart pills will need thorough testing in human trials to confirm both safety and effectiveness before they can receive approval.