Health and Me

Rachel V Thomas

More Than 45% Bacteria In Eye Infections Drug-resistant: Study

Another alarming study has highlighted the growing risk of <span>drug resistance</span>, this time in pathogens responsible for <span>eye infections</span>.

A team of Indian researchers has detected multidrug-resistant bacteria in more than 45 per cent of isolates from patients with eye infections.

The study, jointly led by CSIR-Centre for Cellular and Molecular Biology (CCMB) and LV Prasad Eye Institute (LVPEI), also reported widespread resistance to fluoroquinolones — one of the main classes of antibiotics — across all pathogens examined.

Further, the team found samples with vancomycin-resistant Staphylococcus aureus and extensively drug-resistant (XDR) Klebsiella pneumoniae strains involved in eye infections.

"These findings are worrying because they can spread their AMR genes to other bacteria, too. Also, these pathogens can infect other parts of our bodies," said Karthik Bharadwaj from CCMB. 

The study, published in 'Communications Biology', raise concerns over current treatment approaches in ophthalmic care.

Researchers described the work as one of the most comprehensive genomic analyses of eye pathogens from India to date. CCMB handled genomic and bioinformatics analysis, LVPEI contributed clinical expertise, patient samples, and microbiological characterization, PTI reported.

Whole-genome sequencing helped identify new resistance mechanisms and mutations, offering deeper insight into how these pathogens evolve and spread.

Researchers said the high prevalence of resistance makes such an approach increasingly unreliable. 

<strong>Also read:</strong> <a href="https://www.healthandme.com/health-news/gender-based-violence-surging-global-antimicrobial-resistance-say-experts-article-153845181" data-type="tilCustomLink">Gender-based Violence Surging Global Antimicrobial Resistance, Say Experts</a>

The study underscores the need for microbiology-guided diagnosis and treatment, particularly in severe infections such as microbial keratitis and endophthalmitis. 

"While genomic tools are not yet part of routine clinical workflows, the insights generated through this study provide a critical foundation for developing region-specific treatment guidelines and strengthening antimicrobial stewardship efforts in ophthalmology," said Dr Joveeta Joseph, head of microbiology at LVPEI. 

Researchers also stressed that eye infections should not be viewed in isolation. The microbes involved often originate from the skin or environment, linking ophthalmic infections to the broader AMR burden.

"This study positions the eye as a valuable site for AMR surveillance in the environment around us," said Dr Prashant Garg, executive chair, LVPEI. 

<h2>Increasing Drug Resistance In India</h2>

A recent Lancet Study reported that drug resistance is driving severe typhoid disease, hospitalization, and death among <a href="https://www.healthandme.com/health-news/drug-resistance-driving-severe-typhoid-disease-death-among-children-under-5s-in-india-lancet-study-article-153919123" data-type="tilCustomLink">children under-5s</a> in India.

Another 2024 Indian Council of Medical Research (ICMR)-led study also revealed a significant <a href="https://www.healthandme.com/health-news/indians-are-developing-antibiotic-resistance-against-typhoid-pneumonia-and-urinary-infections-article-151041008" data-type="tilCustomLink">increase in antibiotic resistance</a> and a decrease in the effectiveness of key antibiotics. This indicates a growing public health threat that requires immediate attention.

It showed E. coli, a common bacterium found in both ICU and outpatient settings, demonstrated a concerning rise in resistance to antibiotics like cefotaxime, ceftazidime, ciprofloxacin, and levofloxacin.

<strong>Also read: </strong><a href="https://www.healthandme.com/health-news/study-links-widespread-use-of-antibiotics-during-covid-to-surge-in-amr-cases-article-153872161" data-type="tilCustomLink">Study Links Widespread Use of Antibiotics During COVID To Surge In AMR Cases</a>

<h2>Rising Global <span rel="noindex">Antimicrobial Resistance</span></h2>

Antimicrobial resistance (AMR) occurs when germs develop the ability to defeat the drugs designed to kill them.

It is one of the 10 top global health threats, undermining the effectiveness of essential treatments and placing millions at risk of untreatable infections.

As per WHO data, AMR is an urgent global public health threat, killing at least 1.27 million people worldwide and associated with nearly 5 million deaths in 2019.

The WHO, in a 2025 report, noted that one in six laboratory-confirmed <span>bacterial infections</span> causing common infections in people worldwide in 2023 were resistant to antibiotic treatments.

Health Conditions A-Z

health

more-than-45-bacteria-in-eye-infections-drug-resistant-study

Drug resistance

eye infections

antibiotic resistance

bacterial infections

multidrug Resistant bacteria

Antimicrobial resistance

telangana-makes-cancer-a-notifiable-disease-why-its-important

Telangana Makes Cancer A Notifiable Disease: Why It’s Important?

mystery-illness-kills-5-children-in-rajasthan-in-5-days-8-more-affected

Mystery Illness Kills 5 Children In Rajasthan In 5 days, 8 More Affected

Health News

8 Sit-Up Variations to Strengthen Your Core and Build Stability

Benefits Of Ayurvedic Health Supplement Ashwagandha

9 Anti-Inflammatory Breakfast Options You Should Try

5 Foods You Should Avoid For PCOS, Says Gynecologist

Love Sitting With Your Legs Crossed? Here’s You Should Avoid It

6 Daily Foods That Are Secretly Increasing Your Calories

9 Brain Boosters You Should Do Everyday

Hip Exercises That Will Keep You Flexible As You Age

9 Leg Exercises Office Workers’ Should Do At Home

Benefits of Having Herbal Tea Every Morning

9 Daily Habits That Boost Your Brain Power

Lower-Body Exercises That Are Game-Changers

How Drinking Apple Cider Vinegar Helps You

Aging Myths You Should Never Believe

Superfoods That Support Your Gut Health

What Happens To Your Body When You Eat Instant Noodles Every Day?

Health Issues Premature Babies Often Face

Exercises Office Workers Should Do For Their Heart Health

Reasons Why You Should Add Raw Turmeric To Your Diet

Benefits Of Drinking Milk At Night: Why You Should Do It

Food That Provides Vitamin B12 Naturally In Your Diet

Surprising Health Benefits Of Fenugreek Seeds

9 Superfoods You Should Eat For Your Brain Health

What Does Mental Health Support Look Like At Work?

Long Stretches You Should Do To Unwind From Your Day

Colon Cancer In Young Adults: Early Symptoms You Should Know

Health Benefits Of Eating Dry Fruits Everyday

Are You At Risk For Fried Rice Syndrome?

These Tests Reveal How Well You Are Aging

Lower-Back Exercises You Should Do After A Long-Day's Work

Children’s Diet – What Kids Need To Eat For Immunity Building

Common Diabetes Myths That Could Hurt Your Health

Love Spicy Food? Here’s How It Affects Your Health

Superfood List: Veggies And Fruits You Must Have For Immunity

Foods People With IBS Should Avoid

Exercises To Improve Digestion

Easy Work Lunches You Can Make In The Morning

Hunger Vs Craving: Difference Explained In 60 seconds

These Things Can Cause Your Heart To Age Faster

High Carb Foods That Are Actually Healthy

Another alarming study has highlighted the growing risk of drug resistance, this time in pathogens responsible for eye infections.A team of Indian researchers has detected multidrug-resistant bacteria in more than 45 per cent of isolates from patients with eye infections.The study, jointly led by CSIR-Centre for Cellular and Molecular Biology (CCMB) and LV Prasad Eye Institute (LVPEI), also reported widespread resistance to fluoroquinolones — one of the main classes of antibiotics — across all pathogens examined.Further, the team found samples with vancomycin-resistant Staphylococcus aureus and extensively drug-resistant (XDR) Klebsiella pneumoniae strains involved in eye infections."These findings are worrying because they can spread their AMR genes to other bacteria, too. Also, these pathogens can infect other parts of our bodies," said Karthik Bharadwaj from CCMB.  The study, published in 'Communications Biology', raise concerns over current treatment approaches in ophthalmic care. How Was The Study Conducted?Researchers described the work as one of the most comprehensive genomic analyses of eye pathogens from India to date. CCMB handled genomic and bioinformatics analysis, LVPEI contributed clinical expertise, patient samples, and microbiological characterization, PTI reported. Whole-genome sequencing helped identify new resistance mechanisms and mutations, offering deeper insight into how these pathogens evolve and spread. Researchers said the high prevalence of resistance makes such an approach increasingly unreliable.  Also read: Gender-based Violence Surging Global Antimicrobial Resistance, Say ExpertsThe study underscores the need for microbiology-guided diagnosis and treatment, particularly in severe infections such as microbial keratitis and endophthalmitis.  "While genomic tools are not yet part of routine clinical workflows, the insights generated through this study provide a critical foundation for developing region-specific treatment guidelines and strengthening antimicrobial stewardship efforts in ophthalmology," said Dr Joveeta Joseph, head of microbiology at LVPEI. Researchers also stressed that eye infections should not be viewed in isolation. The microbes involved often originate from the skin or environment, linking ophthalmic infections to the broader AMR burden. "This study positions the eye as a valuable site for AMR surveillance in the environment around us," said Dr Prashant Garg, executive chair, LVPEI.  Increasing Drug Resistance In IndiaA recent Lancet Study reported that drug resistance is driving severe typhoid disease, hospitalization, and death among children under-5s in India. Another 2024 Indian Council of Medical Research (ICMR)-led study also revealed a significant increase in antibiotic resistance and a decrease in the effectiveness of key antibiotics. This indicates a growing public health threat that requires immediate attention. It showed E. coli, a common bacterium found in both ICU and outpatient settings, demonstrated a concerning rise in resistance to antibiotics like cefotaxime, ceftazidime, ciprofloxacin, and levofloxacin. Also read: Study Links Widespread Use of Antibiotics During COVID To Surge In AMR CasesRising Global Antimicrobial ResistanceAntimicrobial resistance (AMR) occurs when germs develop the ability to defeat the drugs designed to kill them.It is one of the 10 top global health threats, undermining the effectiveness of essential treatments and placing millions at risk of untreatable infections.As per WHO data, AMR is an urgent global public health threat, killing at least 1.27 million people worldwide and associated with nearly 5 million deaths in 2019.The WHO, in a 2025 report, noted that one in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments.

more than 45% bacteria in eye infections drug-resistant: study

About Us

Contact Us

Terms & Conditions

Privacy Policy

Company

Health and Me is a premium website with content written and curated to function as a handbook for all Health concerns.

More Than 45% Bacteria In Eye Infections Drug-resistant: Study

Telangana Makes Cancer A Notifiable Disease: Why It’s Important?

Mystery Illness Kills 5 Children In Rajasthan In 5 days, 8 More Affected

Mission ANMOL: Delhi Govt to Screen 2.5 Lakh Newborns Every Year

Health Conditions A-Z

Telangana Makes Cancer A Notifiable Disease: Why It’s Important?

More Than 45% Bacteria In Eye Infections Drug-resistant: Study

Mystery Illness Kills 5 Children In Rajasthan In 5 days, 8 More Affected