Researchers Discover Mifepristone Alternative Amid Legal Battle On Abortion Pills

Updated Jan 27, 2025 | 01:49 AM IST

SummaryAbortion pills are a combination of two medications- mifepristone and misoprostol, which are consumed in two separate doses. Now, researchers have discovered an alternative to mifepristone.
Abortion Pills

Abortion Pills (Credit: Canva)

US Supreme Court overturned the landmark Roe v. Wade decision in 2022, removing federal protection for abortion rights and allowing individual states to determine their abortion laws. This allowed many states to make medical termination of pregnancy completely illegal. Complicating things further, many states put a near ban on abortion pills, including Mifepristone (14 total states). Just recently, multiple states appealed in the country's top court for a complete ban on these pills. However, the justices ruled that the plaintiffs—a group of anti-abortion doctors and activists—did not have the legal standing to sue. Regardless, it left an opening for three states—Missouri, Kansas, and Idaho—to potentially revive their legal challenges on a total ban on Mifepristone pills.

But Why Mifepristone?

Mifepristone is a drug that blocks progesterone, a hormone essential for pregnancy to continue. When used in combination with another medicine, misoprostol, can terminate an intrauterine pregnancy within 10 weeks of gestation (70 days or less from the first day of the last menstrual period).

A New Alternative

As the legal battle continues, a recent study has identified an alternative to mifepristone, offering new hope to women. The research suggests that ulipristal acetate, the active ingredient in emergency contraception pills like ellaOne, could be used as a substitute for Mifepristone.

In the study, 133 women up to nine weeks pregnant were given a 60-milligram dose of ulipristal acetate followed by misoprostol 24 hours later. For 97% of participants, this combination successfully induced abortion—a rate comparable to the effectiveness of the mifepristone-misoprostol regimen. Four participants required additional procedures or medications to complete the abortion.

The 60-milligram dose of ulipristal used in the study is double the standard dose found in ellaOne, which is commonly used for emergency contraception. According to the manufacturer of ellaOne, the drug is designed to prevent pregnancy and does not terminate an existing one. When used as emergency contraception, ellaOne is effective up to five days after unprotected sex. While further research is needed to concretize the discovery, if it works, then ulipristal acetate could become a magic pill for women with unwanted pregnancies.

How Do Abortion Pills Work?

Abortion pills are a combination of two medications- mifepristone and misoprostol, which are consumed in two separate doses. The person may experience cramping and bleeding within a few hours of taking the second medication. This is an indicator that it has worked. The combination of pills is a safe and reliable way to end a pregnancy up to about 12 weeks after the first day of your period. This process can take somewhere between 2 to 3 days to complete, however, symptoms can last for a few weeks. Passing large blood clots may indicate that the embryonic or fetal tissue is exiting your body. Cramping occurs so your uterus can shrink back to its original size. This procedure could be carried out at home. However, a follow-up appointment is suggested to get reassurance.

If you are not aborting at home with the help of the pill, an ultrasound is likely to be performed and you will be given a dissolving tablet that is placed in your vagina, under your tongue or between your cheek and teeth. This will lead to bleeding within 4 hours.

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ByHeart Baby Formula Recalled As 10 US States Report 13 Cases Of Infant Botulism After Use

Updated Nov 9, 2025 | 09:57 AM IST

SummaryThe CDC and FDA have recalled two lots of ByHeart’s organic infant formula after 13 infant botulism cases across 10 states, all requiring hospitalization. Parents are urged to discard affected products, watch for symptoms like constipation and poor feeding, and begin treatment immediately if botulism is suspected. Read on to know more.
ByHeart Baby Formula Recalled As 10 US States Report 13 Cases Of Infant Botulism After Use

Credits: Canva

The Centers for Disease Control and Prevention (CDC), US, has issued a statement recalling an organic baby formula. The company ByHeart Inc's two lots of Whole Nutrition Infant Formula has been recalled, the lots are:

  • Lot: 206VABP/251261P2 ("Use by 01 Dec 2026")
  • Lot: 206VABP/251131P2 ("Use by 01 Dec 2026")

In a statement, the CDC wrote:

CDC and public health officials in several states, the Infant Botulism Treatment and Prevention Program, and FDA are investigating a multistate outbreak of infant botulism linked to recalled infant formula. Infant botulism happens when swallowed spores from a type of bacteria called Clostridium botulinum infects a baby's large intestine and make toxin in it. Infant botulism often starts with constipation but is usually first noticed as difficulty feeding (sucking and swallowing), a weak and altered cry, and loss of muscle tone.

The CDC also notes that 10 states have seen the cases infant botulism. 13 cases have been reported, all of them leading to hospitalization.

The Food and Drug Administration (DA), US has also asked parents and caregivers who have this product to identify the given lot information at the bottom of the packaging and if it matches, they must throw it away. The FDA has said that it is working with retailers to remove "all potentially impacted product" from the store shelves.

FDA has also asked parents who have fed their kids ByHeart's infant formula to keep and eye on them as a precaution and botulism can take two weeks to develop.

The States Which Have Reported The Cases Of Infant Botulism Linked With ByHeart Formula:

  • Arizona
  • California
  • Illinois
  • Minnesota
  • New Jersey
  • Oregon
  • Pennsylvania
  • Rhode Island
  • Texas
  • Washington

What Is Infant Botulism?

Most common form of all botulism in babies, who are between 2 to 8 months old. It happens when the bacteria spores grow in a baby’s intestines and produce the toxin. Honey and contaminated soil can be sources of infant botulism. Adults can also get this type, though it’s rare.

What Are The Symptoms Of Botulism In Infants?

As per CDC, the symptoms include:

  • Most infants with infant botulism will initially develop constipation, poor feeding, loss of head control, and difficulty swallowing
  • If untreated, infants with infant botulism experience a progressive flaccid paralysis that can lead to breathing difficulties and required weeks of hospitalization

The CDC has also recommended that if clinical supports infant botulism then parents and caregivers must begin the treatment and should not wait for laboratory confirmation.

What Did The Makers Of The Infant Formula Say?

ByHeart, which is a New York City based company said that the FDA has as of now tracked 83 reports of infant botulism across the nation since August, 13 of them from the formula. In the statement, the company said: "ByHeart is taking the proactive step to remove any potential risk from the market and ensure the highest level of safety for infants. The FDA has not identified a direct link between any infant formula and these cases and there is no historical precedent of infant formula causing infant botulism."

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Mounjaro Becomes India’s Top-Selling Medicine in October; What’s Driving The Surge

Updated Nov 8, 2025 | 12:01 PM IST

SummaryEli Lilly’s weight-loss and diabetes drug Mounjaro became India’s top-selling medicine by value in October, surpassing GSK’s Augmentin, according to data from Pharmarack. The injectable, launched in March 2025, brought in ₹1 billion in sales as demand for GLP-1 drugs soars.
mounjaro india medicine

Credits: Canva

Eli Lilly’s weight-loss and diabetes injection, Mounjaro, has overtaken GSK’s antibiotic Augmentin (GSK.L) to become India’s highest-selling drug by value in October, as demand for weight-loss treatments continues to surge in the world’s most populated country. According to new data from research firm Pharmarack, the U.S.-based drugmaker’s popular injectable earned ₹1 billion ($11.38 million) in sales last month, compared to Augmentin’s ₹800 million.

While Augmentin still led in overall units sold—5.8 million doses versus 85,000 of Mounjaro—the latter’s premium pricing pushed it ahead in total value, as per Reuters. Analysts say India is rapidly emerging as a major market for obesity treatments, with the global weight-loss drug sector expected to cross $150 billion annually by the end of this decade.

Eli Lilly’s Mounjaro Becomes India’s Top-Selling Medicine in October

Launched in India in March 2025, Mounjaro which helps regulate blood sugar levels and reduces appetite—has seen its sales double within months, surpassing its rival Wegovy by Novo Nordisk, which entered the Indian market in June. Data from Pharmarack shows that Mounjaro has so far generated ₹3.33 billion in total revenue.

“Mounjaro’s consumption in India by volume was nearly ten times higher than Wegovy in October,” said Sheetal Sapale, Vice President (Commercial) at Pharmarack. Eli Lilly sold around 262,000 doses of Mounjaro last month, compared to 26,000 doses of Wegovy. Both drugs belong to the GLP-1 receptor agonist class, designed to treat obesity and type 2 diabetes.

How Does Mounjaro Work?

Mounjaro is a once-weekly injectable medication developed primarily for managing type 2 diabetes. Its key ingredient, tirzepatide, is the first of its kind to act on two gut hormones—GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This dual mechanism makes Mounjaro more advanced than older drugs such as Ozempic (semaglutide) or Victoza (liraglutide), which target only GLP-1, which is thus driving a surge in its sale in india.

Although it was originally approved for diabetes management, Mounjaro has attracted global attention for its strong weight-loss effects. Ongoing studies are evaluating its use for non-diabetic individuals struggling with obesity. The drug mimics the action of GIP and GLP-1, which are hormones released naturally after meals to regulate insulin release, lower blood sugar, and suppress appetite.

Mounjaro for Type 2 Diabetes

For people living with type 2 diabetes, keeping blood sugar in check often requires a combination of medicines, diet adjustments, and regular monitoring. Mounjaro offers a more integrated solution by targeting multiple factors that influence glucose levels. Findings from clinical trials, including the SURPASS-1 to SURPASS-5 studies, show that Mounjaro delivers better outcomes than many existing diabetes treatments, particularly in lowering HbA1c levels—a key marker of long-term glucose control.

Patients using Mounjaro have shown:

  • Lower fasting and post-meal blood sugar levels
  • Reductions in HbA1c by up to 2.5%
  • Improved insulin sensitivity

Mounjaro and Weight Loss

Beyond its use for diabetes, Mounjaro has gained global popularity for its significant role in weight reduction. Clinical studies reveal that people taking the drug often lose between 15% and 20% of their body weight over several months of consistent use. This level of weight loss surpasses that seen with many earlier treatments and even some surgical interventions, making Mounjaro one of the most effective options currently available for managing obesity.

Disclaimer: This article is intended for general information and should not replace professional medical guidance. Always consult your doctor for advice or concerns regarding any health condition.

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Trump Administration May Deny Visas To Obese, Diabetic Immigrants: What We Know So Far

Updated Nov 8, 2025 | 10:23 AM IST

SummaryThe Trump administration is reportedly considering new visa rules that could deny entry to immigrants with health conditions like obesity or diabetes. According to KFF Health News, a State Department cable instructed visa officers to assess applicants based on medical history, financial ability, and even the health of family members.
donald trump mri scan

Credits: CANVA

Following the sharp hike in the H-1B visa fee to $100,000, the Trump administration may soon begin rejecting visa applications from foreigners with certain health conditions, including diabetes and obesity.

While there has been no formal confirmation from U.S. authorities, a report by KFF Health News said a cable from the State Department to embassies and consulates listed new health-related grounds for visa denials.

Trump May Now Deny Entry to Diabetic and Obese Immigrants

According to the report, the guidance instructs visa officers to consider applicants ineligible for entry based on factors such as age and medical conditions, including cardiovascular and respiratory diseases, cancer, diabetes, metabolic and neurological disorders, and certain mental health conditions.

Officers have also been told to evaluate other issues such as obesity — which can contribute to high blood pressure, asthma, and sleep apnea, when assessing whether an applicant might become a “public charge,” or a potential financial burden on the U.S. government.

The guidance further directs officials to determine whether the applicant has sufficient financial resources to pay for their care. “Does the applicant have adequate financial resources to cover the costs of such care over his entire expected lifespan without seeking public cash assistance or long-term institutionalization at government expense?” the cable states.

It adds that individuals who could become a “public charge” — due to age or chronic health problems, may be denied entry for potentially relying on U.S. public resources.

Although the directive applies broadly to most visa categories, it is expected to primarily impact those applying for permanent residency, senior attorney Charles Wheeler told KFF Health News.

Can US Officers Reject Visas Over Health Or Financial Ability?

Visa officers have also been instructed to evaluate whether applicants can afford medical treatment independently, without relying on U.S. public funds.

Wheeler said the new rule gives officers the power to form their own opinions on what might lead to future medical emergencies or financial strain. “That’s concerning because these officers are not medically trained, have no expertise in this area, and should not be making projections based on personal judgment or bias,” Wheeler said.

US Visa Officers To Consider Health Of Applicants’ Family Members

The cable also instructs visa officers to assess the health of applicants’ family members — including children or elderly parents, when determining visa eligibility.

“Do any of the dependents have disabilities, chronic medical conditions, or other special needs and require care such that the applicant cannot maintain employment?” the State Department communication asks.

Currently, immigrant applicants must undergo a medical examination conducted by a doctor approved by the U.S. embassy. The screening includes tests for infectious diseases, an evaluation of mental health history, substance use, and proof of vaccination against illnesses such as measles, polio, and hepatitis B.

However, immigration lawyer Sophia Genovese from Georgetown University noted that the new guidance expands these requirements by directing officials to weigh long-term health conditions, not just communicable diseases, when reviewing visa applications.

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