Health and Me

Itisha Arya

This Everyday Supplement May Quietly Cut Your Alzheimer’s Risk, New Study Suggests

alzheimer risk supplement

New findings suggest that a common supplement might play a role in lowering the risk of Alzheimer’s disease. Researchers have found that a naturally occurring amino acid may help stop the build-up of harmful plaque in the brain. Alzheimer’s remains the leading cause of dementia and often brings changes in memory, communication and behaviour. 

Experts believe the condition begins when certain proteins collect in and around brain cells. One of these proteins, amyloid, can form thick deposits that interfere with how the brain functions. Recent work now indicates that a simple oral supplement may help limit amyloid levels.

<h2>A Supplement That May Help Protect The Brain</h2>

The study, published in Neurochemistry International, showed that <span>arginine</span>, a naturally present amino acid, could reduce the clumping of amyloid and lessen its damaging effects in animal models of Alzheimer’s. 

Arginine, sometimes listed as l-arginine, helps the body build proteins and is found in foods such as meat, fish, nuts, seeds and dairy. It is also available in supplement form. Researchers stressed that the doses used in their experiments were specific to the study and do not match the amounts sold in commercial supplements. Professor Yoshitaka Nagai, who led the research, said the results suggest that arginine has the ability to curb this build-up both in lab testing and in living organisms.

Professor Nagai explained that the discovery is especially encouraging because arginine already has a well-established safety record and is relatively affordable. This combination, he noted, makes it a promising candidate for future therapeutic use. Reports from Science Daily highlight that the animals given oral arginine developed fewer amyloid plaques and showed a drop in insoluble Aβ42 in the brain. These mice also performed better in behavioural assessments and showed reduced activity of inflammatory genes linked to the progression of Alzheimer’s.

<h2>How <span rel="noindex">Arginine Affected Brain Changes</span> In Mice</h2>

The research team believes that these results may help spark new ideas for preventing Alzheimer’s or slowing its progression. Professor Nagai said that the findings could be useful not only for Alzheimer’s but also for other disorders linked to abnormal protein folding. He added that because arginine is low-cost and already considered safe for general use, it could move into clinical testing more quickly than many experimental drugs. Even so, researchers cautioned that more preclinical work and human-based studies are needed before any firm conclusions can be made about recommended doses or long-term impact.

According to the <span>NHS</span>, early Alzheimer’s often begins with noticeable memory problems. A person in the initial stages may show signs such as:

• Forgetting recent events or conversations

• Struggling to recall names of common places or objects

• Having difficulty finding the right words

• Showing weaker judgement or taking longer to make decisions

• Becoming less adaptable or more resistant to changes

Anyone who notices these changes in themselves or a loved one should consider seeking advice from a GP.

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New findings suggest that a common supplement might play a role in lowering the risk of Alzheimer’s disease. Researchers have found that a naturally occurring amino acid may help stop the build-up of harmful plaque in the brain. Alzheimer’s remains the leading cause of dementia and often brings changes in memory, communication and behaviour. Experts believe the condition begins when certain proteins collect in and around brain cells. One of these proteins, amyloid, can form thick deposits that interfere with how the brain functions. Recent work now indicates that a simple oral supplement may help limit amyloid levels.A Supplement That May Help Protect The BrainThe study, published in Neurochemistry International, showed that arginine, a naturally present amino acid, could reduce the clumping of amyloid and lessen its damaging effects in animal models of Alzheimer’s. What Is Arginine?Arginine, sometimes listed as l-arginine, helps the body build proteins and is found in foods such as meat, fish, nuts, seeds and dairy. It is also available in supplement form. Researchers stressed that the doses used in their experiments were specific to the study and do not match the amounts sold in commercial supplements. Professor Yoshitaka Nagai, who led the research, said the results suggest that arginine has the ability to curb this build-up both in lab testing and in living organisms.Professor Nagai explained that the discovery is especially encouraging because arginine already has a well-established safety record and is relatively affordable. This combination, he noted, makes it a promising candidate for future therapeutic use. Reports from Science Daily highlight that the animals given oral arginine developed fewer amyloid plaques and showed a drop in insoluble Aβ42 in the brain. These mice also performed better in behavioural assessments and showed reduced activity of inflammatory genes linked to the progression of Alzheimer’s.How Arginine Affected Brain Changes In MiceThe research team believes that these results may help spark new ideas for preventing Alzheimer’s or slowing its progression. Professor Nagai said that the findings could be useful not only for Alzheimer’s but also for other disorders linked to abnormal protein folding. He added that because arginine is low-cost and already considered safe for general use, it could move into clinical testing more quickly than many experimental drugs. Even so, researchers cautioned that more preclinical work and human-based studies are needed before any firm conclusions can be made about recommended doses or long-term impact.Signs of Alzheimer’s diseaseAccording to the NHS, early Alzheimer’s often begins with noticeable memory problems. A person in the initial stages may show signs such as:• Forgetting recent events or conversations• Misplacing belongings• Struggling to recall names of common places or objects• Having difficulty finding the right words• Repeating questions• Showing weaker judgement or taking longer to make decisions• Becoming less adaptable or more resistant to changesAnyone who notices these changes in themselves or a loved one should consider seeking advice from a GP.