A rapidly spreading strain of H5N1 avian influenza, more commonly referred to as bird flu, has ravaged bird populations worldwide. Since 2022, over 147 million birds in the U.S. alone have been affected, causing economic strain, increasing egg prices, and growing public health concerns. The virus has also begun spreading to other mammals, including dairy cows, cats, and even humans. The question of the day stands tall: what if bird flu mutated to turn airborne and effectively spread among people? Scientists warned that such mutation would be all it took for the next great global pandemic. Understanding Bird Flu: What makes it dangerous?

Bird flu is one of the forms of influenza which mainly infects birds but occasionally jumps to humans and other mammals. The high fatality rate among infected humans makes H5N1 more alarming. Similar to human flu viruses such as H1N1 and H3N2, H5N1 also has distinct protein structures that will not let it spread from one person to another, at least for now.

There are two major known subtypes of avian flu that have infected humans: influenza A(H5N1) and influenza A(H7N9). WHO reports that H5N1 mortality in the Western Pacific Region has reached up to 54% among reported cases. Despite the fact that human infections are rare, health experts are always worried about mutation.

Can Bird Flu Become Airborne?

Currently, H5N1 is not yet able to be transmitted from person to person by the air, although viruses are found to evolve. If H5N1's genetic makeup is changed in such a manner that it can be airborne, scientists fear that it may lead to a deadly pandemic. Unlike seasonal influenza, which spreads by respiratory droplets, bird flu is mainly transmitted by direct contact or any exposure to the infected animal or their body fluids. However, airborne transmission would mean the virus could spread much more easily, making containment significantly more difficult.

Researchers are keeping a close eye on cases in mammals, as transmission among non-bird species may be a sign that the virus is adapting. Pandemics such as the 1918 Spanish flu have, in the past, originated from animal influenza viruses that mutated to become highly transmissible in humans. If H5N1 takes this path, the world may be facing a severe public health crisis.

How Do Humans Get Infected with Bird Flu?

Although it is rare, bird flu can be transmitted to humans. Infected birds spread the virus through their saliva, mucus, and excrement. Other infected animals, like dairy cows, can also harbor the virus in their respiratory secretions, milk, or blood. In these cases, the virus is transferred to humans by direct contact with infected animals or surfaces. These viruses may enter the body through the eyes, nose, or mouth and can be inhaled via airborne particles, such as dust.

Although human infections have been few, the threat remains that each new case increases the possibility of mutation. The Centers for Disease Control and Prevention, U.S. emphasizes that the risk to the general population remains low, but cautions close contact workers who work closely with animals, like farmworkers and veterinarians.

Symptoms and Duration of Bird Flu Infection in Humans

The incubation period for H5N1 in humans varies but generally ranges between 2 to 5 days, with some cases taking up to 17 days to manifest symptoms. Common symptoms include:

• Fever
• Fatigue
• Cough
• Muscle aches
• Sore throat
• Nausea and vomiting
• Diarrhea
• Stuffy or runny nose
• Shortness of breath (dyspnea)
• Pink eye (conjunctivitis)

Most recent U.S. cases have been mildly symptomatic but, worldwide, H5N1 infections have caused severe respiratory illness and sometimes death. Mortality has been high in all previous outbreaks; thus, officials are on their toes in regard to new infections.

Who's at Greatest Risk?

The people at high risk of acquiring bird flu are those who are in close contact with infected animals, such as poultry farm workers, veterinarians, and dairy farmers. Also, people whose immune systems are weakened, including young children and older adults, are more susceptible to severe illness. Although this is rare, there have been documented cases of limited human-to-human transmission, especially among family members caring for infected individuals.

Are Eggs Safe To Eat?

Well, health experts have assured me that properly cooked poultry and eggs do not harbor the virus of avian bird flu. Also, high heat will kill such a virus for human consumption; however, sometimes birds get flu even after ingesting raw commercial pet food leading to the transfer of the diseases in under-cooked animal-based food products.

Raw milk from infected cows remains a potential risk, though more research is needed to determine the extent of its transmissibility. The CDC advises avoiding raw dairy products and ensuring that all poultry and eggs are thoroughly cooked before consumption.

Preventive Measures: How to Stay Safe

Although the current level of risk in humans is quite low, extra precautions are best taken, starting with people regularly in contact with birds or live stocks. Such precautions have included the following recommendation by the CDC:

• Avoid all direct contact with sick or dead birds and animals.
• Use adequate protective equipment- gloves, mask, goggles-as needed to collect potentially infected animals.
• Wash hands well afterwards with soap, water, antiseptic cleaners, and all poultry and its products.
• Poultry and eggs should be cooked to an internal temperature of 165°F/74°C.
• Pasteurized dairy products are the safest options.

Monitor for symptoms if you have been exposed to infected animals. Seek medical attention if flu-like symptoms occur.

The Uncertain Future of H5N1

Although the threat of an airborne mutation is speculative at this point, scientists warn against complacency. Surveillance programs monitor changes in the virus, and vaccine development is ongoing to prepare for a potential outbreak.

Like all other emerging infectious diseases, preparation is essential. Public health officers encourage further studies and collaboration that would ensure an early detection and control of H5N1 before it even threatens the entire world.

For now, the risk of a bird flu pandemic is low, but the experience with COVID-19 teaches that preparedness should be proactive. Understanding the risks, staying informed, and following recommended safety protocols can help to minimize potential dangers in the years ahead.

Every year on 25 April, World Malaria Day is observed to raise awareness about one of the deadliest yet preventable diseases. As per the World Health Organization (WHO), there were 263 million malaria cases and 5,97,000 malaria deaths across 83 countries in 2023. The WHO African Region carries a disproportionately high share of the global malaria burden. As per the numbers, this Region was home to 94% of the malaria cases, accounting for 246 million and 95% of malaria deaths. Children under 5 accounted for about 75% of all malaria deaths in the Region.

Ahead of World Malaria Day, WHO also called for renewed efforts at all levels - from global policy to community action to accelerate progress towards eliminating malaria.

World Malaria Day 2025 Theme

This year, WHO has joined the RBM Partnership to End Malaria and other partners in promoting: "Malaria Ends With US: Reinvest, Reimagine, Reignite". This is a grassroot campaign that aims to re-energize efforts at all levels, from global policy to community action, to accelerate progress towards malaria elimination.

World Malaria Day History

World Malaria Day was first celebrated internationally in 2008, building upon the earlier "Africa Malaria Day", which had been observed b African countries since 2001. The date, April 25, was established by WHO in 2007 during the World Health Assembly. In 2007, it was the 60th session of the World Health Assembly where the proposal to rename Africa Malaria Day to World Malaria Day was made to acknowledge the global presence of malaria.

World Malaria Day Significance

The day has a strong significance in healthcare as it brings attention to the disease that still continues to take so many lives, especially in low-income and tropical regions. It also serves as an important reminder to continue spreading awareness about the disease as well as promoting its prevention, treatment and continuous international cooperation to fight against it.

What Is Malaria?

The WHO describes malaria as a life-threatening disease spread to humans by some types of mosquitoes, mostly found in tropical countries. However, they are preventable and curable.

WHO notes: "Malaria is spread to people through the bites of some infected anopheles mosquitoes. Blood transfusion and contaminated needles may also transmit malaria. The first symptoms may be mild, similar to many febrile illnesses, and difficult to recognize as malaria. Left untreated, P. falciparum malaria can progress to severe illness and death within 24 hours.

There are 5 Plasmodium parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat. P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa. The other malaria species which can infect humans are P. malariae, P. ovale and P. knowlesi."

What Are The Symptoms?

The early symptoms are fever, headache and chills, which can usually start within 10 to 15 days of getting bitten by an infected mosquito.

Some types of malaria can cause severe illness and death. Infants, children under 5 years, pregnant women, travellers and people with HIV or AIDS are at higher risk. Severe symptoms include:

• extreme tiredness and fatigue
• impaired consciousness
• multiple convulsions
• difficulty breathing
• dark or bloody urine
• jaundice (yellowing of the eyes and skin)
• abnormal bleeding

A new AI-powered blood test that can detect 12 types of cancer is to be tested on NHS patients. Using this test, experts would now be able to detect cancerous cells in people much before the symptoms appear. The trial, conducted on 8,000 patients, will analyse blood samples for tiny fragments of genetic material released by tumours.

The test called miONCO-Dx, was created using data from 20,000 patients. Initial tests have produced promising results, having shown that it can detect 12 of the most lethal and common cancers, including bowel cancer, at an early stage, with over 99% accuracy. With no other trial currently working in the same way, this is a world-leader and will support in placing Britain at the forefront of revolutionising healthcare. Notably, the UK government has awarded £2.4m to run the trial of the genetic test, which was developed by the University of Southampton and the biotech startup Xgenera.

How Does It Work?

The test was created by Xgenera, in collaboration with the University of Southampton. As little as 10 drops of blood are all that's needed to detect up to 12 common cancers. The test works by measuring the microRNA in a blood sample and using AI to identify if cancer is present and, if so, where it is located in the body.

What Cancers Will It Detect?

Lung, gastric, prostate, oesophageal, liver, bladder, ovarian, bowel, pancreatic and breast cancers–as well as bone and soft tissue sarcoma and a type of brain tumour. The Department of Health said the test was now ready for the "validation and verification" stage.

Professor Sir Stephen Powis, NHS England's national medical director, said: "This blood test has the potential to help us detect bowel cancer earlier and reduce the need for invasive tests, and the next step in this trial will now be vital in gathering further evidence on its effectiveness and how it could work in practice."

How Is A Blood Test Conducted?

A blood test is a simple medical procedure used to check various health conditions. Here's how it is typically conducted:

1. Preparation: Depending on the test, you may be asked to fast for 8–12 hours. The healthcare provider will explain any specific instructions.

2. Collection: You’ll usually be seated or lying down. A healthcare professional will tie a tourniquet around your upper arm to make the veins more visible. The inside of your elbow is the most common site for drawing blood.

3. Cleaning: The area is cleaned with an antiseptic to reduce the risk of infection.

4. Drawing Blood: A sterile needle is inserted into the vein, and blood is collected into one or more vials or tubes.

5. Post-collection: Once enough blood is collected, the needle is removed, and a cotton ball or bandage is applied to stop any bleeding.

6. Processing: The blood samples are then sent to a lab for analysis.

Novovax, the maker of the only protein-based COVID-19 vaccine available in the US announced that its shot is on track for full approval from the US Food and Drug Administration (FDA). It is an important development for the company. It has sent its stock soaring up to 21% on Wednesday morning for trading. It is said that this will also ease the fears of political interference that may have caused delay in the process.

Vaccine For Emergency Use Only

While the other mRNA vaccines from Pfizer and Moderna have received full FDA approval for specific age groups, Novovax's vaccine still awaits the approval. It is only authorized for emergency use.

The emergency use authorization or the EUA allows vaccines to be distributed during public health emergencies. However, once the emergency ends, the FDA can remove them from the market unless full approval is granted.

Why Did The Delay Happen?

The FDA originally planned to approve Novovax's vaccine by April 1. However, as per the inside sources, the process was paused at the direction of Dr Sara Brenner, the FDA's acting commissioner. The delay has also raised concerns, especially after Dr Peter Marks, the FDA's longtime vaccine chief, reportedly left his post due to disagreements with the Health Secretary Robert F Kennedy Jr, who is a known vaccine skeptic.

What Makes Him A Vaccine Skeptic?

In the past, RFK Jr. has worked closely with many anti-vaccine activists who work for his nonprofit group Children's Health Defense. While in his recent speech, he said that he has "never been anti-vax and have never told the public to avoid vaccination", his track record shows otherwise.

In a podcast interview, he said, "There is no vaccine that is safe and effective" and told FOX News that he still believes in the now long-debunked idea that vaccines can cause autism. In another 2021 podcast, he urged people to "resist" CDC guidelines on getting their kids vaccinated. "I see somebody on a hiking trail carrying a little baby and I say to him, better not get them vaccinated," he said.

His non-profit also led an anti-vax campaign sticker and he appeared next on the screen to a sticker that read: "If you are not an anti-vaxxer you are not paying attention," reports AP.

What Does The Vaccine Need For Approval?

The FDA recently asked Novavax to outline a plan to collect additional clinical data from people who have received the vaccine. Novavax says it is “engaging with the FDA expeditiously” and hopes to secure full approval as soon as possible. Full FDA approval is considered the gold standard, as it reflects a higher level of scrutiny and confidence in a product’s safety and effectiveness.

How Is This Vaccine Different From Others?

The COVID-19 vaccines that are currently available in the US teach the immune system to recognize the virus' spike protein, which is its outer coating. the Pfizer and Moderna's mRNA vaccine deliver genetic instructions that help the body create a temporary version of spike protein that trigger an immune response. In contrast, the Novovax's shot contains lab-grown copies of the spike protein itself, which are then combined with a substance that boosts the immune response.

This traditional approach—called a protein-based vaccine—has been used for decades in vaccines for diseases like hepatitis B and shingles. For people who are hesitant about mRNA vaccines, Novavax offers an alternative that uses a well-established method.