Many people are not aware that the popular foods they enjoy eating or processed snacks that add to their daily consumption could have carcinogenic components. While you may not see immediate effects, they slowly chip away at your health causing you long term damage. A new study from China has found a worrying connection between aspartame, a common artificial sweetener, and glioblastoma, which is the most aggressive kind of brain cancer. This research, published in Scientific Reports, used mouse models to investigate how aspartame affects gut bacteria and how those changes might influence the development of glioblastoma. How Aspartame Might Help Tumors Grow Scientists discovered that aspartame might create the right conditions in your gut to help tumors grow. Specifically, people who had more aspartame also had less of a certain type of bacteria in their gut. This type of bacteria has been linked to other health problems before, like being overweight or diseases like Parkinson's. The study also found a link between aspartame and how certain genes work inside brain cancer tumors. The researchers said their findings are important for understanding how safe artificial sweeteners are and how they might affect cancer growth. This new information could lead to new ways to treat this aggressive brain cancer, possibly by focusing on genes or using treatments that involve gut bacteria. The scientists plan to keep studying how aspartame changes things in the body and around tumors. Past Worries and How Much is Okay This isn't the first time aspartame has been a concern. Before, some health groups said aspartame might "possibly cause cancer" in humans, but they didn't have strong proof. There's a daily limit for how much aspartame is considered safe: 40 milligrams for every kilogram of your body weight. So, if you weigh 80 kilograms, you shouldn't have more than 3.2 grams of aspartame in a day. Even though this seems like a lot, aspartame is in many everyday "diet" or sugar-free foods and drinks. For example, some diet sodas can have 200 milligrams of aspartame in just one can. It's also in some medicines and chewable vitamins. Experts say it's about 200 times sweeter than regular sugar. Ongoing Debate About Aspartame's Safety Even though many health organizations around the world say aspartame is safe, scientists have been worried about it in studies for many years. However, a big review of these studies in 2019 said there were no major health risks or benefits from artificial sweeteners. This was mainly because many studies were small, short, or not very well done. A similar review in 2022 also mentioned "possible negative health effects with long-term use," but again, the proof wasn't strong enough. These "negative health effects" included worries about getting overweight, type 2 diabetes, heart disease, and even a shorter lifespan. Healthy Eating and Role of Aspartame's Completely avoiding aspartame would be really hard, and it might not even be necessary. Experts suggest that eating a wide variety of plant-based foods (like fruits, vegetables, beans, and nuts) is the healthiest choice. It's also less healthy to eat a lot of highly processed foods, which are more likely to contain aspartame. So, try to pick fresh ingredients, fruits, vegetables, beans, nuts, and seeds whenever you can.