Credits: AP, TradeIndia
US President Donald Trump held a press conference to announce the connection between the use of Tylenol, a popular pain and fever relief medicine during pregnancy and autism. Trump in the press conference also suggested Leucovorin, as a potential treatment for autism symptom.
Read: Tylenol And Autism: Trump Announces Link Between The Two, Science Does Not Back Him
It is known as folinic acid, a form of folate, also an essential B vitamin or B9, which has been approved by the US Food and Drug Administration (FDA) for counteracting the toxic effects of certain cancer drugs. It can counteract methotrexate that blocks body's use of folate.
The drug is also used to enhance the effects of chemotherapy drugs and to treat specific types of anemia.
The drug can be administered orally or intravenously. While it is manufactured by dozens of companies, notes US FDA, on Monday itself, FDA published a notice to the Federal Register ahead of Trump's press conference to approve a version of Leucovorin manufactured by GlaxoSmithKline or GSK.
GSK had previously withdrawn from FDA's consideration when it stopped making the drug. However, as per the FDA notice, "The FDA is working with GSK, the innovator of Wellcovorin (leucovorin calcium), on a process to include the essential scientific information needed for the safe and effective use of these drug products for adults and pediatric patients with CFD (cerebral folate deficiency)."
As per the FDA notice, leucovorin calcium, branded as Wellcovorin by GSK is sent for approval for patients with cerebral folate deficiency, which is a neurological condition that affects folate, an essential vitamin for brain health, transport into the brain.
The FDA notice mentions that individuals with CFD have been "observed to have developmental delays with autistic features".
FDA Commissioner Marty Makary, MF, MPH said that in over two decades, the US has "witnessed a tragic four-fold increase in autism". He further noted: "Children are suffering and deserve access to potential treatments that have shown promise. We are using gold standard science and common sense to deliver for the American people.”
George Tidmarsh, MD, PhD, Director of the FDA's Center for Drug Evaluation and Research said that FDA is collaborating with GSK to broaden the existing Wellcovorin label and is committed to "finding and treating the root causes of autism".
Read: Trump's Claim On Linking Tylenol And Autism Is Unscientific, According To Doctors
Doctors have been using leucovorin off-label for autism, repurposing the drug beyond its original approval, reported Reuters.
Research from SUNY Downstate Medical Center and others suggests that as many as three-quarters of children with autism may have genetic variations or autoimmune issues that interfere with folate processing in the brain.
Smaller studies have linked these problems to more severe autism symptoms and found that leucovorin treatment may help improve speech, social interaction, and irritability. Still, the Autism Science Foundation cautions that the research is in its early stages, and more evidence is needed before firm conclusions can be drawn.
Read: Trump Suggests Changes In Childhood Vaccines, Says It Is Based On What He Feels
A 2016 study published in Molecular Psychiatry, which was a randomized controlled trial suggested that this specialized form of folate can improve communication and language skills in some children with Autism Spectrum Disorder (ASD).
A June 2020 study published in the Seminars in Pediatric Neurology suggests folate (vitamin B9) plays a vital role in brain development and function, helping with DNA synthesis, methylation, and neurotransmitter production. Some children with autism struggle with folate metabolism, particularly in transporting folate into the brain, a condition known as cerebral folate deficiency.
Another 2020 study published in October in Seminars in Pediatric Neurology suggests that in many cases, the immune system produces antibodies that target the folate receptor alpha (FRα) on brain cells. These folate receptor autoantibodies (FRAA) block folate entry into the brain, resulting in low brain folate levels even when blood levels are normal. While only about 5–10% of the general population carries these antibodies, research suggests that 50–70% of children with autism may have them. This disruption is thought to significantly affect speech and cognitive development.
However, Dr. David Mandell, a professor of psychiatry and autism expert at the University of Pennsylvania, told Reuters that leucovorin might well be a possible treatment for some children with autism, "but the evidence we have supporting it... is really, really weak."
Credit: X
Two people have suffered burn injuries in Mumbai after a cluster of gas-filled balloons exploded and turned into a ball of fire inside a residential building’s lift earlier this week.
The incident occured at Anmol Towers, a residential building opposite a petrol pump in Mumbai's Goregaon West and police have registered a case against the balloon vendor, according to NDTV.
CCTV footage shows a woman entering the lift with a small trolley, followed by a man carrying several balloons packed in a large bag. Moments later, the balloons mysteriously caught fire, leading to the blast inside the elevator.
Despite flames briefly covering the CCTV camera, the woman and two men were seen running out of the elevator seconds later. In the end, the clip shows the elevator doors shutting as flames erupt at the centre of the lift.
It was unclear what type of gas was used to inflate the balloons. However, while many consumers assume decorative balloons are filled with helium, a non-combustible gas, authorities and safety experts suggest that it is highly possible that hydrogen was used instead.
Mumbai police have urged the public to exercise caution and warned balloon sellers against using flammable gases, particularly in residential buildings and enclosed areas.
Hydrogen has a very wide range of flammability in air (4-75 percent by volume) and requires very low energy to ignite. It often causes explosions rather than just fires, especially in confined spaces.
In high concentrations in enclosed areas, hydrogen acts as a simple asphyxiant by displacing oxygen, which can lead to dizziness, unconsciousness, or death. Additionally, hydrogen fires burn with a nearly invisible, pale blue flame, making them almost impossible to detect with the naked eye during daylight.
Moreover, hydrogen gas also burns faster than most conventional fuels, increasing the risk of deflagration (subsonic) or detonation (supersonic).
On the other hand, as a noble gas, helium has a completely filled outer shell of electrons, meaning it does not react with other elements or catch fire in the presence of oxygen and heat.
Along with this, unlike hydrogen, which is also lighter than air but highly explosive, helium will not ignite even if exposed directly to a flame or spark and it can can act as a buffer and actually suppress flames by displacing oxygen in the immediate area.
For minor burns, immediately run cool (not cold) water over the area for 10–20 minutes, remove jewelery or tight clothing near the injured area and cover with a sterile bandage. A minor burn might need emergency care if it affects the eyes, mouth, hands or genitals.
However, for serious and large burns, protect the burned person from further harm and ensure that they are breathing. Loosely cover the area with gauze or a clean cloth and raise the burned area above heart level, if possible.
As you call emergency services, watch for symptoms of shock which include cool, clammy skin, weak pulse and shallow breathing.
Seek immediate care for burns, which:
Globally, about 10 million people experience burns and about 180,000 die from them each year.
A woman with no travel history has died from Nipah virus in Bangladesh, the World Health Organization has confirmed.
The patient, aged between 40 and 50, developed a fever and headache-like symptoms consistent with the virus, followed by hypersalivation, disorientation and convulsion on 21 January.
The case was reported in the northern Naogaon district, Sharmin Sultana, senior scientific officer at the Institute of Epidemiology, Disease Control and Research, later said.
She died on January 28 and was confirmed to be infected with the virus the day after. Although she had no travel history, she regularly consumed raw date palm sap, reports suggest.
The WHO said all 35 people who had contact with the now-deceased patient were being monitored and have tested negative for the virus. No new cases had been detected to date.
Since its emergence in 2001, Bangldesh has reported cases of Nipah virus in humans every year. In 2025, four laboratory-confirmed fatal cases were reported in the country.
The Nipah virus outbreak began in West Bengal, India in January with two hospital nurses at AIIMS, Kolkata, testing positive for the infection and being quarantined, prompting widespread testing. Soon after, five cases, including a doctor and a staff member, were confirmed and over 100 people were quarantined.
However, one of the nurses, a 25-year-old unidentified man has now made a recovery and revealed his experience with the virus, claiming that despite irritation in the throat and uncertainty about what lay ahead, he had faith in his doctors and fellow nurses.
In an interview with the Metro, he said: “After I was taken off ventilation and regained consciousness, I came to know that I have Nipah. I still had the tube in my mouth, and there was irritation. Despite the irritation and my fear, I had faith in the doctors and nurses.
“I have suffered and I know the symptoms. I will tell people when they should get checked for the Nipah virus. I want to raise awareness about the virus and its symptoms.
“I am not sure how I came in contact with the deadly virus. Maybe it was while treating a patient. But I will continue to work as a nurse. I am waiting to rejoin the hospital,” he added.
The unidentified healthcare professional remains very weak physically and is undergoing physiotherapy to regain his strength. “I was bedridden for over a month. I am still very weak and have an unstable gait. So, I am undergoing physiotherapy,” he said.
The other nurse, a woman, remains in a coma but has been taken off ventilation support, a hospital official confirmed this week.
According to WHO, Nipah virus is a zoonotic illness which means it is mostly transmitted from animals to humans through bats. However, it can also spread through fruits that have been contaminated by the saliva, urine or droppings of infected bats. Human-to-human transmission can also occur through close contact with an infected person or their bodily fluids.
The illness has a 75 percent fatality rate, and there are no vaccines to protect the public.
The virus was first identified in 1998 during an outbreak among pig farmers in Malaysia and soon made its way to India and Bangladesh in 2001, with cases often involving family members or caregivers tending to the infected patient.
READ MORE: Nipah vs Bird Flu in India: Which Virus Poses A Greater Threat To Humans?
Although the Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people. Some of its common symptoms include:
Samples collected from the patient’s home and workplaces, including pets and partially eaten fruits dropped by bats, all tested negative for the virus, and the exact source of the infection could not be identified.
Credits: Canva
Wet Wipes Waring: 59 people have fallen ill, with one dead, after using non-alcoholic, non-sterile, infected wet wipes in UK. The UK Health Security Agency (UKHSA) and Medicines and Healthcare products Regulatory Agency (MHRA) issued a warning, and said that there is still "an ongoing risk of infection associated with their use". The bacteria that is causing this infection is burkholderia stabilis or B. stabilis.

The UKHSA also in its warning included names of four different wet wipes and asked people to avoid using them.
The Pharmaceutical Journal noted that the UKHSA and MHRA published a joint statement that warned people that they should not use non-sterile, non-alcoholic wipes in their homes and first-aid kits.
After an outbreak investigation conducted by MHRA in 2025, four products were identified to be contaminated with Burkholderia stabilis. “There have been 59 confirmed cases of Burkholderia stabilis associated with some non-sterile alcohol-free wipe products — identified in an outbreak in the United Kingdom from January 2018 to 3 February 2026,” the statement said.
“A small number of cases continue to be detected. These have included some serious infections which have required hospital treatment and one death has been attributed to Burkholderia stabilis infection.”
UKHSA and MHRA is telling people to look out for wipes marked 'sterile' to be used on wounds or broken skin.
UKHSA on its official website notes: 'Burkholderia are a type of bacteria found naturally in the environment, including in soil and water. Burkholderia stabilis is one species within this group. While many people never encounter problems with this type of bacteria, it can cause serious infections in certain circumstances, particularly among vulnerable individuals.'
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The UKHSA notes: "The risk of acquiring infection is generally very low. Infections can occur through contact with contaminated products on broken or damaged skin, or through introduction of bacteria through medical devices such as intravenous lines."
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