Every year on September 21, World Alzheimer's Day is observed. It is a global effort to raise awareness and challenge the stigma around Alzheimer's disease and other dementia.

Alzheimer's is a severe brain disorder of memory loss and confusion. If it is not diagnosed and managed on time, it can also adversely impact one's mental abilities of learning, thinking, reasoning, remembering, problem-solving, decision-making, and attention.

Every year, a particular theme is followed, this year, the theme is "Time to act on dementia, Time to act on Alzheimer's".

The theme focuses on attitudes towards dementia and addresses the stigma and discrimination that still exists. Some of the common attitudes towards dementia are the common belief that dementia is a normal part of ageing, with 62% of healthcare practitioners actually believing it to be true. 35% of carers had hidden a diagnosis of dementia and 1 out of 4 thought that nothing could be done about it.

History

The first time this day was introduced was in 1994 in Edinburgh, on the occasion of the 10th anniversary of Alzheimer's Disease International (ADI). This organisation was founded in 1984 to support and guide Alzheimer's disease patients and their families.

The organisation also runs Alzheimer's University and aims to connect people around the world to promote Alzheimer's Month, which is also celebrated in September.

What Is Dementia, What Is Alzheimer's?

As per Neha Sinha, Dementia Specialist, CEO and Co-founder of Epoch Elder Care, it is a progressive decline in cognitive abilities, including memory, language, problem-solving and other thinking skills. It is severe enough to interfere with daily life. "It primarily affects older adults, with Alzheimer's being the most common," she says.

Alzheimer's accounts for 60 to 80% of all dementia cases around the world. It is estimated that the prevalence of Alzheimer's worldwide is around 2.4 crores.

While Dementia is the general term for a range of symptoms that affect cognitive abilities, while Alzheimer's is the most common form of dementia.

Shilpi Saraswat, Clinical Psychologist at Sakra World Hospital, Bengaluru points out that the main risk factors of dementia are age, genetics, long-term health conditions, lifestyle choices such as smoking or excessive alcohol use, one's gender and cognitive reserve.

Dementia In Indian Household

Sinha points out that in India, the subtle onset of dementia is quietly emerging as a silent epidemic, affecting millions of households across the country. As per the Neurological Health Atlas of India, 8.8 million elderly are currently living with dementia. "A number that can be doubled by 2036," says Sinha.

Sinha also points out that since its earliest symptoms are often ignored as signs of early ageing, Dementia stays ignored and creeps into the household unnoticed.

"Discovering Alzheimer’s early can be a pivotal moment, offering a window of opportunity that changes the course of the disease. With an early diagnosis, we can initiate medical treatments and a management plan, that may slow down the progression, giving patients and their loved ones more quality time together," says Sinha.

When care is tailored to the person, not just the disease, it profoundly enhances their quality of life. It’s about more than just managing symptoms—it’s about nurturing emotional well-being, maintaining dignity, and providing the support that adapts as the disease evolves.

Can Hearing Loss Lead To Dementia?

While age is one of the risk factors in dementia, Dr Sanjay Sachdeva, a senior ENT at HearClear India suggests a link between hearing loss and dementia.

As per a study by the Lancet Commission on Dementia, untreated hearing loss can give rise to greater cognitive decline and even account for approximately 8% of dementia cases worldwide. This means, 8 lakh of the nearly 1 crore new cases of dementia are diagnosed every year.

"Considering that auditory information plays a pivotal role in forming memories and associations, hearing impairment interferes with the brain’s ability to process auditory information, which consequently deteriorates memory and learning abilities," says Dr Sachdeva. Additionally, hearing loss in ageing people can go beyond the inability to hear things and can contribute to social isolation in them.

What Can Help Reduce It?

Saraswat point out that by modifying 12 risk factors through lifestyle changes, 40% of the dementia cases can be delayed.

Some of the specific actions include maintaining systolic BP of 130 mm Hg or less in midlife from around age 40 years (antihypertensive treatment for hypertension is the only known effective preventive medication for dementia).

Encouraging the use of hearing aids for hearing loss and reduce hearing loss by protecting of ears from excessive noise exposure.

Other such prevention methods include:

• Reduce exposure to air pollution and second-hand tobacco smoke.
• Prevent head injury.
• Limit alcohol use, as alcohol misuse and drinking more than 21 units weekly increase the risk of dementia.
• Avoid smoking uptake and support smoking cessation to stop smoking, as this reduces the risk of dementia even in later life.
• Provide all children with primary and secondary education about brain health.
• Reduce obesity and the linked condition of diabetes. Sustain midlife, and possibly later life physical activity.
• Addressing other putative risk factors for dementia, like sleep, through lifestyle interventions, will improve general health.

Health officials in the United States have raised alarms after confirming cases of a more severe mpox strain, known as Clade I, in California. This marks the first reported instance of this strain spreading locally, as previous US cases had all been linked to international travel.

So far, three cases have been confirmed across Southern California, including Los Angeles County and Long Beach. All patients required hospitalization but are now recovering at home. The discovery has triggered concern among health experts as Clade I mpox is known to cause more serious illness than the milder Clade II strain that led to the 2022 global outbreak.

What Is Clade I Mpox?

Mpox (formerly called monkeypox) is caused by a virus from the same family as smallpox. There are two main genetic variants or clades that infect humans, Clade I and Clade II.

While Clade II was responsible for the global outbreak in 2022–23, Clade I has historically circulated in parts of central and western Africa. It is associated with more severe disease, higher rates of complications, and in some cases, fatalities, particularly among children, pregnant women, and people with weakened immune systems.

Experts are now investigating how this strain might have started circulating within US borders and whether community transmission is occurring.

Early Signs and Symptoms to Watch For

Mpox usually begins with flu-like symptoms and can be easily mistaken for a seasonal illness in its early stages. Common early signs include:

• Fever, chills, or sweating
• Headache and muscle aches
• Fatigue or weakness
• Swollen lymph nodes
• Sore throat or nasal congestion

Within a few days, a distinctive rash develops, starting as red spots that progress into fluid-filled blisters or pustules. These can appear on the face, palms, soles, genitals, or even inside the mouth and eyes. The rash typically scabs over and heals within two to four weeks.

In more severe Clade I infections, complications may include secondary bacterial infections, prolonged healing, scarring, eye involvement leading to blindness, or inflammation of internal organs. In rare cases, systemic infection can occur, posing life-threatening risks.

Who Is Most at Risk?

Certain groups are more likely to contract or develop severe mpox:

• Those in close, intimate, or prolonged contact with an infected person
• Individuals who share contaminated clothing, bedding, or surfaces
• People exposed to respiratory droplets through face-to-face interaction
• Individuals with multiple sexual partners or exposure in commercial sexual venues
• People with compromised immunity, such as those living with HIV, cancer, or transplant recipients

Children and pregnant women

Public health experts emphasize that awareness of symptoms and early diagnosis are key to preventing further spread.

How to Stay Safe

While most mpox cases are not fatal, Clade I poses a higher risk, making prevention critical. Health agencies recommend the following:

• Avoid direct contact with people who have rashes or lesions resembling mpox.
• Do not share personal items like towels, bedding, or clothing.
• Practice good hand hygiene, wash hands often with soap and water or use an alcohol-based sanitizer.
• Use masks in crowded or high-risk settings where close contact occurs.
• Seek medical attention immediately if you notice suspicious rashes or flu-like symptoms after possible exposure.

Experts also stress that vaccines used during the 2022 outbreak, such as Jynneos, remain effective against both Clade I and Clade II strains. Vaccination, combined with early treatment and isolation of confirmed cases, is expected to play a crucial role in containing the spread.

The Long Beach Department of Health and Human Services has confirmed its first case of locally acquired Clade-1 Monkeypox strain. In a recent press release, the authorities informed the citizens that the person who was diagnosed had no recent travel history, which means the virus was contracted locally.

While the risk for the public remains low, the health department warns people to stay safe. Since it is a contagious disease, the health investigation is still ongoing, as the public officers comb through the person’s history. However, currently there are no other cases of the clade 1 mpox. Mayor Rex Richardson said, “While the overall risk of mpox clade I exposure to the public remains low, we are taking this very seriously and ensuring our community and health care partners remain vigilant so we can prevent any more cases.”

What Is Mpox?

According to the World Health Organization, Mpox (previously called monkeypox) is a sickness caused by a virus. Think of it as being like different types of flu—there are a few versions of the mpox virus, called clades.

The global outbreak that happened in 2022–2023 was caused by one of these versions, specifically Clade IIb. The virus spreads through close contact with an infected person's sores or body fluids, with contaminated items like bedding, or with infected animals. The virus can also be passed from a pregnant person to their baby.

Most mpox treatment involves supportive care—doctors help manage symptoms like pain and fever while the body recovers. This includes keeping the patient well-nourished and hydrated, caring for the rash, and addressing any secondary infections. Fortunately, vaccines are available for mpox.

How is Clade 1 Different From Clade 2?

This new case involves Clade 1 mpox, which is historically associated with more severe illness and is typically found in Central and East Africa.

In contrast, the large 2022-2023 outbreak in the U.S. and globally was caused by Clade 2, which usually results in milder illness. Mpox, regardless of the clade, spreads through direct contact with sores, body fluids, intimate contact, or contaminated items. Symptoms can include a rash or sores, fever, chills, sore throat, swollen lymph nodes, and body aches.

What Are The Health Risks of Mpox?

Long Beach health officials are currently investigating the patient's source of exposure and conducting contact tracing, though no other cases have been identified so far.

Long Beach Mayor Rex Richardson emphasized that while the overall risk to the public remains low, the city is taking the situation seriously. He stressed the importance of continued surveillance, early response, and vaccination.

A Long Beach public health physician, Dr. Cliff Okada, advised: "Anyone with an unexplained rash or lesions should seek care promptly. Speak openly with intimate partners and your healthcare provider. Early action protects you and others."

Who Is At Risk For Mpox Clade 1?

The Centers for Disease Control and Prevention (CDC) continues to recommend the Jynneos vaccine for people at high risk of exposure. This includes gay, bisexual, and other men who are intimately involved with other men, transgender and non-binary people, those with weakened immune systems (such as people with HIV), individuals exposed to an infected person, those with occupational exposure, and people traveling to areas with ongoing outbreaks.

Most mpox patients recover on their own within 2 to 4 weeks. A booster shot is not currently recommended for those who have completed the two-dose vaccine series.

Liam Payne's death marks a whole year, and his girlfriend Kate Cassidy reflected on his death anniversary. She also opened up about her depression after his death. Cassidy lost her boyfriend, former One Direction member in 2024, and as she said, her world collapsed.

The 26-year-old social media star has now opened up about her painful journey through grief, depression, and eventually healing.

In an interview to Page Six, she said, "I was always just kind of doing nothing and just dealing with that grief and pain. I was admittedly mired in depression and just not wanting to really live my life.”

For weeks, Cassidy found herself unable to function, trapped between disbelief and heartbreak. But around two months later, something shifted.

“I finally realized, ‘OK, like I need to live my life. I need to get up, get out of bed,’” she recalled.

The Way To Healing

However, she was determined to pull herself out of darkness and so she began to rebuild her days, one small habit at a time. She started to set her alarm earlier each morning, forcing herself to wake up and move. "I began working out, eating clean," she said. "I like to always be up early, have a workout class planned, go for a nice walk, eat cleaner. For me, being active always keep my mind so much cleaner and healthier," she explained.

Gradually, she also learned to navigate her life without Payne, and kept herself busy. She said that she tried to be as busy as she can to help her headspace.

Also Read: Liam Payne Investigation: How Pink Cocaine Affects You?

Acknowledging The Hard Truth

Payne's death was a devastating news for her as well as for her fans. The 31-year-old singer died in October 2024, after falling from a third-storey balcony at the CasaSur Palermo Hotel in Buenos Aries, Argentina.

An autopsy report later revealed that Payne had drugs in his system and the authorities determined that he fell to his death while trying to escape the hotel room after he was locked in.

Cassidy had joined Payne on the trip, but returned home two days before his death. Following his death, she revealed that they had talked about spending their lives together. "We had so many plans. He lit up my room. He was just so sweet, so funny. I've never met anybody like him and I'm sure I probably won't ever meet anybody like him in my life."

Almost a year later, Cassidy is filled with both sorrow and gratitude. "In a way, I am glad that he is going to be that one person. He was the best person I ever met."

Cassidy said that through grief she is learning to embrace life again.

What Depression Feels Like After You Lose Someone

Cassidy opened up that right after losing Payne, she felt like she could not live anymore. While grief and loss is a natural emotional response to the loss of someone close, often, one slips through depression, if they are not able to cope with the loss.

Depression is a mood disorder and it causes a persistent feeling of sadness, and further affects your emotional and physical well-being.

NHS UK notes that people who deal with grief and loss feel shock and first and numb after and then they go into the phase of overwhelming sadness, tiredness, exhaustion, and sometimes anger.

However, there are things one can do, notes NHS UK, which includes talking to a friend, a mental health expert, go for peer support, and try to bring in simple lifestyle changes to help you feel more in control and able to cope.