Every year on the second Thursday of March, we observe World Kidney Day to raise awareness about kidney health and its essential role in our overall well-being. This year, the day falls on March 13. Such health days are important as it highlights the need for paying attention to each part and organ of our body, which is essential to keep us going.

The kidneys are two bean-shaped organs which act as body's most essential and primary filtration system. They remove waste products and excess fluid from the blood.

The day is important to highlight because more often than you think, kidney diseases go unnoticed. Max Healthcare, a hospital chain in India states that 8 to 10% of adults are affected with some form of kidney damage. However, not many know about it, until severe complications arise. Each year, millions die prematurely from such conditions, this is why early detection is important as it can make a significant difference.

Theme For World Kidney Day

This is what has reflected in this year's theme for World Kidney Day: "Are Your Kidneys OK? Detect Early, Protect Kidney Health". This year's theme aims to target the importance of regular checkups for early detection and intervention at the right time to prevent any kidney disease.

As per the National Institutes of Health (NIH), the kidneys are important to maintain a healthy balance of water, salts, and minerals. These are extremely essential for regulating blood pressure, producing red blood cells, and ensuring overall body equilibrium.

What Happens When Your Kidney Fails?

When kidneys fail to perform its primary function, which is to filter out the waste and produce erythropoietin, which is a hormone that stimulates red blood cell production, it can lead to health complications. Your body gets filled with extra water and waste products, this condition is called uremia. As a result, your hands and feet may also swell. At the time of complete and irreversible kidney failure, your kidneys stop working completely. This condition is called End-stage renal disease or ESRD.

History of World Kidney Day

This day was for the first time observed in 2006 as a joint initiative by the Internal Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF). The aim back then too was to raise awareness about kidney health and to promote preventive measures to reduce the burden of kidney diseases worldwide. Since then, it has been observed on every second Thursday of March, every year.

Significance of World Kidney Day

The significance of World Kidney Day lies in its role in addressing the growing prevalence of kidney diseases. Many of the cases go undiagnosed. Other than that there are many cases among children where parents do not know whether it is a kidney disease or an unrelated infection. Thus this day also highlights the importance of paying attention to your child's health for any pediatric kidney issues. As this disease is often associated with adults only, but not always is this the case.

ALSO READ: Why Do Cases Of Pediatric Kidney Issues Go Unnoticed?

More than 1,000 measles cases have been confirmed across the United States in 2025, a saddening milestone of the nation's struggle with a disease it was officially announced as eliminated as far back as the year 2000. State and regional health agencies along with the Centers for Disease Control and Prevention report at least 1,002 cases so far this year—an astonishing number putting 2025 on pace to equal 2019, which was the century's worst measles year to date.

Most of these instances are a result of a fast-growing outbreak with its hub in West Texas, which has already spread to New Mexico, Oklahoma, and potentially Kansas. With underreporting anticipated and additional states preparing for increasing numbers, the true extent of this crisis may be much greater than present numbers indicate.

Measles was officially eliminated in the U.S. in 2000, thanks to extensive vaccination campaigns and strong public health infrastructure. During the past two decades, the nation experienced comparatively low case numbers—approximately 180 per year on average.

But the peace was broken in 2019, when 1,274 cases appeared during large outbreaks in New York City and surrounding communities. After a temporary hiatus during the COVID-19 pandemic, cases of measles started creeping back up again, peaking in this year's record-breaking increase.

The 2025 outbreak is particularly concerning because it implies systemic vulnerabilities in immunization coverage and public health readiness. Recent statistics show that just 4% of reported cases involved vaccinated individuals, affirming the vaccine's effectiveness but also highlighting the increasing numbers of individuals opting to forego vaccination altogether.

This resurgence is not confined to the United States. Across the Americas and parts of Europe, measles rates are rising sharply. In Canada, over 1,000 cases have been confirmed, a stunning leap from just 12 cases in 2023. Mexico has also reported over 400 confirmed cases, with additional suspected infections under investigation. In Europe, measles rates are now at their highest level in 25 years.

The World Health Organization (WHO) has raised alarms for both North and South America as high-risk areas, attributing declining vaccination levels, post-pandemic health disruption, and global mobility as main drivers for this resurgence.

Why Is Measles So Dangerous?

Measles is not an innocent childhood disease—it is extremely contagious and can result in severe complications, such as pneumonia, brain swelling (encephalitis), blindness, and even death. Three deaths—two of them children—have already been reported in the U.S. this year alone. The 2025 hospitalization rate is around 13%, highlighting the severity of the disease.

The basic reproduction number (R0) of measles—the number of individuals an infected person will, on average, transmit the virus to—is between 12 and 18, far more contagious than influenza or even COVID-19. Such high transmissibility makes vaccination not merely critical, but critical for disease control.

The present epicenter of the outbreak, Texas, has seen 702 confirmed cases in 29 counties, with 91 hospitalizations and three deaths as of May 6. What began as a localized cluster has blown up into a full-blown epidemic—illustrating just how rapidly measles can get out of hand in under-vaccinated communities.

Other states with significant outbreaks are Ohio, Montana, and Michigan, all having over three connected cases—the CDC's criteria for classifying an outbreak.

What If Herd Immunity Is No Longer Enough?

Herd immunity works because of a threshold level of the population (about 95%) getting vaccinated to safeguard those who are unable to be vaccinated because of age, allergy, or pre-existing medical conditions. The principle is quite simple: if enough individuals are immunized, the virus cannot circulate freely, and high-risk groups are still protected.

What Happens When Vaccination Rates Fall?

Current evidence indicates that this is occurring. In certain populations, immunization rates have collapsed as a result of refusal to be vaccinated and misinformation campaigns, stripping away the protective barrier that previously held back measles. The consequences are serious:

• Local outbreaks rapidly develop into regional epidemics, particularly in crowded or highly mobile populations.
• High-risk groups, such as infants, the immunocompromised, and the elderly, are put at increased risk.
• Healthcare systems get overwhelmed with avoidable diseases, sucking resources that could be used for other emergencies.
• As community immunity is lost, endemic transmission—where measles becomes perpetually present year after year—becomes an imminent possibility.

A 2025 study puts the current rate of vaccination at an estimate of 850,000 cases of measles over the next 25 years if it continues as is. With declining vaccine use, this figure could reach 11 million. They're not theoretical predictions—they're evident warnings based on facts.

Individual responsibility is not something to be substituted with herd immunity. If everyone is exempting themselves, the defense is lost. Even then, the immunized individuals stand to suffer as well due to sheer virus burden and possibility of breakthrough cases in compromised hosts.

How to Strengthen Yourself and Prevent Measles Spread?

For undoing this dismal trend, concerted action from public health officials at the earliest is paramount. This comprises:

• Public education campaigns to combat misinformation.
• School vaccination requirements and more stringent exemption policies.
• Improved surveillance and reporting systems to monitor outbreaks in real-time.
• Support for international immunization efforts, since infectious diseases do not recognize borders.

Programs such as Vaccines for Children have long assisted in keeping immunization rates high. Reinvesting in and updating these programs will be critical in avoiding future outbreaks.

The U.S. stands at a crossroads. The 2025 measles outbreak is more than a public health tale—it's an alarm call. Having a disease be "eliminated" does not equate to having won the war. In a time of international mobility, vaccine reluctance, and fractured public confidence, we have to recall that prevention is only effective if we all move together. Herd immunity used to suffice. It might not anymore.

In the biggest drug crackdown, US authorities have seized more than three million pills—the largest fentanyl drug seizure in DEA history. The bust, which resulted in the arrest of 16 people, allegedly dismantled a large drug trafficking operation associated with Mexico's brutal Sinaloa cartel. This historical seizure underscores not just the magnitude of the synthetic opioid epidemic engulfing America but also the ghastly strength of fentanyl itself- a substance causing thousands of overdose fatalities every year.

The biggest fentanyl seizure in DEA history is both a victory and an admonition. It highlights the magnitude of the threat and reminds us that one pill, one dose, is potentially lethal. As a world community, we need to come together on solutions that meet medical demand and public safety before more lives are lost to an opioid that brings pain relief at one end and fatal dependency at the other.

As we make our way through the implications of this large-scale federal operation, it is important to know what fentanyl is, why it's so lethal, and how it is being abused globally.

What is Fentanyl?

Fentanyl is a man-made opioid initially designed for pain control, particularly for patients who are having major surgery or who suffer from extreme chronic pain. FDA-approved, it is a quick-acting narcotic painkiller that is almost 100 times more powerful than morphine and 50 times more potent than heroin. In a clinical setting, fentanyl is given by experts by injection, transdermal patches, or lozenges under close supervision.

Yet beyond the edges of clinical usage, fentanyl has become a public health debacle.

On the street, fentanyl is disguised under innocently sounding names like Dance Fever, China Girl, Goodfellas, Tango & Cash, and Murder 8. The names sound innocuous, but they cover up a lethal reality. Traffickers are now cutting fentanyl with other drugs like heroin and cocaine or stamping it into fake pills that look just like prescription drugs like oxycodone and Xanax—so that unsuspecting users can't tell what's harmless and what's deadly.

The three million fentanyl-contaminated pills taken by the DEA were suspected of being produced in clandestine labs, most likely using precursors purchased in China and processed by Mexican drug cartels.

How Fentanyl Is Taken and Why That Makes It More Dangerous?

Illegal fentanyl is ingested in so many different ways—smoking, snorting, swallowing in pill or tablet form, absorption using blotter paper, or taking with transdermal patches. The number of ways it is ingested raises the risk of overdose since users do not know how much fentanyl they are actually taking.

Worst still, users often think they're taking a less powerful drug when, in reality, they are taking a medication that can suspend their breathing in minutes.

What Happens to the Body When You Use Fentanyl?

Initial effects of fentanyl are similar to other opioids: pain alleviation, elation, and profound relaxation. But the danger profile is so much higher with its potency. Side effects could be:

• Sleepiness and giddiness
• Confusion
• Nausea and vomiting
• Sedation
• Respiratory depression
• Pupillary constriction (pinpoint pupils)

Symptoms in overdose situations can rapidly increase and may include:

• Stupor or coma
• Cold, clammy skin
• Blue lips or nails (cyanosis)
• Slow or ceased breathing to a dangerous level

These symptoms can lead to death in just minutes if not treated immediately with naloxone, an opioid antagonist.

Medical Use vs Misuse of Fentanyl

Care needs to be made between the use of fentanyl in a medical setting and abuse. In the hospital and tightly controlled medical environment, fentanyl is an essential drug for patients with pain that is resistant to other opioids. It's carefully given in minute amounts and while closely monitored.

Patients on fentanyl for pain control must be carefully watched for tolerance—a situation in which the same dose, over time, becomes less potent and dependency. Tolerance does not equal addiction, though. Under medical direction, fentanyl can be safely tapered off in order to prevent withdrawal symptoms.

Physicians also caution patients to not stop taking the drug abruptly, as it can cause withdrawal, which while not fatal, is very painful.

What are the Side Effects Of Fentanyl Use?

Aside from immediate effects, long-term fentanyl use—even when prescribed—can interfere with the body's natural hormone balance, decrease adrenal function, and cause muscle rigidity or hypotension (low blood pressure). In extreme cases, allergic reactions can occur, such as swelling of the face or throat, which needs emergency treatment.

The users should seek consultation with their care team if they experience symptoms such as nausea, unexplained fatigue, or difficulty staying awake—indications that the drug is impacting their central nervous system or endocrine system.

The record-breaking seizure by the DEA is a critical milestone, but it’s just one chapter in an ongoing battle. The opioid epidemic, fueled in large part by fentanyl, claimed more than 70,000 American lives in recent years, and the problem shows no signs of abating.

Public health professionals caution that education, awareness, and access to treatment are critical to stemming this crisis. Naloxone needs to be made widely available, and stronger international cooperation to break up the transnational supply chains facilitating fentanyl distribution is required.

The United Kingdom is witnessing an alarming surge in norovirus infections that has led the National Health Service (NHS) to take extreme action. With multiple wards at Bedford Hospital in the Highlands shutting their doors to new admissions and restricting visitors, the outbreak has rapidly grown into a public health issue that has echoed far beyond British shores. Health officials and epidemiologists are cautioning that this could be just the start of a second wave of infections—fueled by changing viral strains and a lack of population immunity.

As health systems around the world continue to struggle with pandemic fatigue and systemic strain, the norovirus comeback provides a timely reminder: hygiene, surveillance, and public awareness are still pillars of infectious disease prevention.

The Bedford Hospital outbreak is not unique. As reported by the UK Health Security Agency (UKHSA), norovirus cases have increased dramatically since February, hitting record levels since the agency started collecting comparative data in 2014. NHS England said hospitalizations for the virus have jumped to an average of 1,134 patients per day—nearly twice as many as the same time last year.

The GII.17 strain, which was the predominant genotype for the first half of the winter, comprised 59% of cases reported. Its prevalence fell from 76% in November, however, and was replaced by the GII.4 strain, which increased from 10% to 29% over the past three months. The shift in strains may imply that people who were infected with one strain remain susceptible to another, making containment and immunity difficult.

What Is Norovirus?

Traditionally referred to as the "winter vomiting bug," norovirus is a highly contagious virus that causes acute gastroenteritis or inflammation of the stomach and intestines. It infects others quickly through food, water, surfaces, and contact with other people. Typical symptoms include sudden nausea, vomiting, diarrhoea, cramping of the abdomen, and sometimes low-grade fever, aches, and headaches.

Unlike influenza, norovirus does not yield to antiviral drugs. It typically lasts for 1–3 days, but the illness can be particularly severe in young children, older adults, and those with compromised immune systems because of the danger of dehydration.

Why Are Hospital Wards Being Shut?

Bedford Hospital's action in closing off affected wards and restricting visiting is in line with the high transmissibility of norovirus, especially in closed settings such as hospitals and care homes. Amy Douglas, UKHSA Lead Epidemiologist, emphasized that the presence of several genotypes simultaneously raises the risk of reinfection, placing a further burden on already overcrowded hospitals running with 95.3% adult beds in use.

Saffron Cordery, NHS Providers' acting chief executive, shared the concern, pointing to high pressure on emergency services, loss of paramedic hours due to ambulance handover delays, and delays in discharging clinically ready patients—a perfect storm that could overwhelm the system.

While the outbreak at present is focal in the UK, the potential for international spread is considerable. The characteristics of international travel, climate fluctuations, and high-density urban living allow norovirus to spread freely across borders. Based on estimates, for each laboratory-confirmed case in the UK, there are around 288 unreported community cases, suggesting a possible national burden of more than 3 million cases per year.

This is a cause for concern for health authorities across the globe. Outbreaks in closed and semi-closed settings such as schools, cruise ships, nursing homes, and healthcare facilities can lead to rapid spread and high absenteeism.

How to Protect Yourself and Stay Safe?

Although there is no vaccine available for norovirus at the moment, there are definite measures that one can take to reduce risk:

1. Prioritize Proper Handwashing

Hand sanitizers work very poorly on norovirus. Wash your hands frequently with soap and warm water, particularly after going to the toilet, after handling dirty diapers, and before preparing food or eating.

2. Do Not Prepare Food if You Are Sick

In case you are vomiting or experiencing diarrhoea, avoid handling food for others for a period of at least 48 hours after your symptoms have ceased. This is when you're most contagious still.

3. Sanitize Surfaces Properly

Use bleach-based cleaners to clean kitchen counters, bathroom faucets, and high-touch surfaces. Norovirus lasts for days on surfaces if not sanitized.

4. Stay Home If You're Sick

As a student, employee, or caregiver, it's imperative you quarantine yourself for a minimum of 48 hours after the symptoms have disappeared to avoid infecting others.

5. Stay Hydrated

Vomiting and diarrhoea can lead to rapid dehydration. Increase fluid intake with water, oral rehydration salts, or electrolyte drinks. Watch for signs of severe dehydration—dry mouth, dizziness, and low urine output—and seek medical attention if they occur.

What Are Authorities Doing About It?

The UK government is taking preventative measures, such as introducing RSV vaccination campaigns and new hospital guidelines. Experts, however, say that in the absence of public compliance and hygiene awareness, such outbreaks can become the norm.

NHS England's National Medical Director, Professor Sir Stephen Powis, appealed to the public to use NHS 111 and its website for non-emergency questions to take the strain off emergency departments.

Health and Social Care Secretary Wes Streeting recognized the continued pressure and reconfirmed the government's promise to reform the system: "These figures indicate that we are not yet out of the winter woods yet."

The surge of norovirus infections in the UK is a stark reminder of how rapidly an infection that's seasonal can quickly become a national health issue. It demands increased vigilance about hygiene, infection control, and healthcare system strength—not only in the UK but everywhere.