Your eyes could be giving you clues that your kidneys aren’t working the way they should. While most people associate kidney trouble with tiredness, swelling, or changes in urination, the effects can also show up in your vision. To understand this better, we spoke with Dr Manoj K. Singhal, Principal Director of Nephrology and Kidney Transplantation at Max Super Speciality Hospital, Vaishali.

5 Eye Symptoms Linked to Kidney Issues

The kidneys filter toxins and help maintain balance in the body. But when they start to weaken, some of the earliest signs may appear in unexpected places, like your eyes. Some of these symptoms, as per Dr Manoj are:

1. Persistent Puffiness

It’s normal to wake up with puffy eyes, but if the swelling doesn’t fade even after rest, it could point to protein leaking into your urine, a condition called proteinuria, which often signals kidney damage.

2. Blurred or Double Vision

Sudden blurriness may be tied to high blood pressure or diabetes—two major causes of kidney problems. These conditions damage small blood vessels in the eyes and can even lead to sudden vision loss.

3. Dry, Itchy Eyes

Many people with chronic kidney disease, especially those on dialysis, experience dryness or irritation in the eyes. This happens when mineral balance in the body is disrupted, leaving the eyes feeling gritty or uncomfortable.

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4. Red or Bloodshot Eyes

Frequent redness can be a warning sign of uncontrolled blood pressure or diabetes. In some rare cases, kidney-related conditions like lupus nephritis can also cause eye problems.

5. Difficulty Seeing Colours

Kidney disease can sometimes affect the optic nerve or retina, making it harder to distinguish certain colours, especially shades of blue and yellow.

When To Seek Help?

Not every eye problem points to kidney disease, but if these symptoms persist or worsen, it’s worth getting both your vision and kidney health checked. Routine eye exams can sometimes reveal early warning signs before bigger problems develop.

If you notice changes in your eyesight alongside other symptoms like fatigue, swelling, or urinary changes, don’t ignore them. Catching kidney issues early can make all the difference for both your eye health and your overall well-being.

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How To Protect Your Kidneys and Eyes

While some kidney issues are unavoidable, there are steps you can take to reduce your risk and protect both your kidney and eye health, as suggested by Dr Manoj:

• Maintain a Healthy Blood Pressure and Blood Sugar: High blood pressure and diabetes are major risk factors for kidney disease. Regular monitoring and a balanced diet can help keep these in check.
• Stay Hydrated: Drinking enough water supports kidney function and helps flush out toxins.
• Eat a Balanced Diet: Focus on fruits, vegetables, whole grains, and lean proteins while limiting salt, processed foods, and excess sugar.
• Exercise Regularly: Physical activity improves circulation and helps maintain healthy blood pressure, supporting both kidney and eye health.
• Avoid Smoking and Excess Alcohol: Both can damage blood vessels, increasing the risk of kidney and eye problems.
• Schedule Regular Checkups: Routine blood tests, urine tests, and eye exams can help catch early signs of kidney issues before they worsen.

Taking care of your overall health is the best way to safeguard your kidneys. and your eyes from long-term damage.

An international group of scientists has created an artificial intelligence tool that can estimate a woman’s likelihood of developing breast cancer within the next four years.

The AI tool, known as the BRAIx risk score, analyzes mammogram images to generate an individualized risk assessment and flag women who may face a higher chance of developing the disease.

It may not only show the current risk but also predict the future risk, enabling early detection and treatments for a better outcome.

According to the findings published in The Lancet Digital Health journal, nearly one in 10 women ranked in the top 2 percent of risk by the AI tool were diagnosed with breast cancer within four years. This was despite previously receiving a clear screening result.

“These risk scores enable future development of personalized screening pathways to transform population breast cancer screening and save lives,” said corresponding author Helen M. L. Frazer of the University of Melbourne.

Frazer noted that identifying women who appear cancer-free but carry very high risk -- comparable to those with inherited BRCA1 or BRCA2 mutations -- will unravel both hereditary and non-hereditary causes of breast cancer.

From one-size-fits-all screening to personalization

Breast cancer screening programs have significantly lowered mortality rates -- by roughly 40-50 percent among women aged 50 to 74. However, most screening systems still apply the same approach to all women, regardless of individual risk.

Traditional screening tools use genetics, breast density, and questionnaires to estimate breast cancer risk. On the other hand, new AI-based screening tools, such as BRAIx personalizes screening by gathering information already present in breast scan images to better identify who is at higher risk.

“Our results show that conventional mammographic density is a far weaker predictor of breast cancer risk than the BRAIx risk score, even for interval cancers,” the researchers said in the paper. Interval cancers are aggressive tumors diagnosed after a negative mammogram.

The BRAIx Tool

The BRAIx risk score was developed using mammograms from nearly 400,000 women. To prove its efficacy, the AI tool was tested on data from almost 96,000 women from Australia and then confirmed in an independent Swedish population of over 4,500 women.

The findings showed that:

• The BRAIx risk score estimated breast cancer risk more accurately than the traditional risk factors, such as breast density, country of birth, and even family history.

• For the top 2 percent of women with the highest BRAIx risk score, the probability of a cancer diagnosis within 4 years was 9.7 percent -- a risk level exceeding that typically seen in women with inherited BRCA1 or BRCA2 mutations.

The BRAIx risk score can:

• Make breast screening more personalised,
• Improve early cancer detection,
• Reduce false alarms,
• Save lives without increasing costs

Global Breast Cancer Burden

Breast cancer continues to be the most common cancer among women worldwide.

A recent study published in The Lancet Oncology journal predicted that the number of new cases of the deadly disease will reach more than 3.5 million globally in 2050 -- rising by a third from 2.3 million in 2023.

Annual deaths from the disease will also rise by 44 percent -- from around 764,000 to 1.4 million.

However, not smoking, getting sufficient physical activity, lowering red meat consumption, and having a healthy weight can help prevent over a quarter of healthy years lost to illness and premature death from breast cancer.

People who survived a COVID-19 infection can be at significant risk for kidney disease, acute kidney injury, and chronic kidney disease. compared to individuals who were not infected, according to a study.

The study, published online in the journal Communications Medicine, revealed that COVID patients have

• a 2.3-times higher risk of acute kidney injury
• a 1.4-times higher risk of chronic kidney disease
• a 4.7 times higher risk of kidney failure

“While we’re in the post-pandemic era, this shows that COVID-19 history is an important variable when considering the long-term impact of the infection on kidney function and disease,” said first author Yue Zhang, who was at Pennsylvania State University, US, while conducting the study. Zhang is currently a postdoctoral scholar at Johns Hopkins Bloomberg School of Public Health.

How Was The Study Conducted?

For the study, data on over 3 million working-age adults in the United States were analyzed.

The team compared the effect of influenza, another common viral infection that affects kidney health, and people with a history of COVID infection on kidney infections.

Using a machine learning model, the individuals were followed between 180 and 540 days for the emergence of new acute or sudden kidney disease.

The results showed that:

• Both COVID and the flu can worsen kidney health
• Flu caused a mild and temporary effect
• COVID increased the risk of acute kidney injury for a longer duration
• COVID survivors developed kidney disease within a few hours to a few days
• COVID patients had a longer-term chronic and end-stage kidney disease.

How COVID Worsens Kidneys Health

The Penn State researchers explained that kidney cells express high levels of the primary protein receptors that SARS-CoV-2 uses to enter and infect cells. Kidney cells also produce specialized enzymes that help viruses enter cells.

According to Kidney Health Australia, an acute COVID infection can impact the kidneys with fevers and respiratory symptoms, and/or worsening blood sugar control.

The US National Institutes of Health stated that renal dysfunction is an increasing clinical indicator of COVID propagation.

Citing several studies, the NIH said that the most common clinical manifestation is proteinuria -- found in more than half of the COVID patients. In addition, hematuria, elevated blood urea nitrogen, and elevated serum creatinine are other common features in Covid survivors with poor kidney health.

Nasr Ghahramani, Professor of Medicine at Penn State College of Medicine, stressed the need for COVID survivors, especially those with diabetes and high blood pressure, to take "more frequent and more prolonged monitoring of their kidney function" to enable early detection and better outcomes.

When Demi Moore stepped onto the red carpet at the 2026 Actor Awards, the conversation quickly shifted away from couture and glamour. The 63 year old actor wore a striking black Schiaparelli gown with a dramatic feathered train, but what truly caught public attention was her noticeably thinner frame.

Photos from the event spread rapidly across social media, and many fans expressed worry over what they described as a “skeletal” appearance. Some questioned whether the transformation was intentional. Others speculated whether she may have used Ozempic, the diabetes medication that has become synonymous with rapid celebrity weight loss.

There has been no confirmation that Moore used any weight loss medication. Still, the public reaction reflects a growing anxiety about how quickly bodies can change in the era of injectable weight loss drugs.

The Ozempic Question

Ozempic was originally developed to help manage type 2 diabetes. Its active ingredient, semaglutide, works by mimicking a hormone that regulates blood sugar and appetite. Over the past few years, it has gained immense popularity for its ability to produce significant weight loss.

But as prescriptions surged, so did questions about side effects. One of the biggest concerns is loss of lean mass, which includes muscle.

Research published in Cell Metabolism examined how semaglutide affects body composition. In animal studies, overall lean mass dropped by about 10 percent during weight loss. Interestingly, much of that loss was not from skeletal muscle but from organs like the liver, which can shrink as body fat decreases. Some skeletal muscles did shrink slightly, by about 6 percent on average, while others remained unchanged.

However, other human studies suggest that people taking semaglutide may lose a substantial amount of muscle along with fat. One study found that around 39 percent of the weight lost was muscle. Research on tirzepatide, another injectable drug, showed muscle loss closer to 25 percent of total weight reduction.

It is important to note that muscle loss is not unique to Ozempic. Anytime someone loses a large amount of weight, whether through dieting, surgery, or medication, about one quarter to one third of that loss can come from muscle. When calories are restricted, the body taps into stored energy from glycogen, fat, and muscle.

The problem is that muscle matters. Losing muscle lowers metabolic rate, increases fatigue, and can raise the risk of falls or injury, especially in older adults. For women over 60, rapid weight loss may also affect bone health.

Why Rapid Weight Loss Raises Red Flags

When a public figure appears dramatically thinner within a short span of time, people naturally worry. Rapid weight loss can sometimes signal aggressive calorie restriction, illness, or medication side effects.

Even when weight loss is intentional, the speed matters. Quick changes can strain the body, impact strength, and alter facial structure, which may explain why some fans said Moore looked “different” rather than simply “slimmer.”

Healthy weight loss is not just about a number on the scale. It is about preserving muscle, supporting metabolism, and protecting long term health.

How To Lose Weight Without Losing Strength

If someone chooses to pursue weight loss, whether naturally or with medical supervision, protecting muscle should be a priority.

Prioritize protein. Most adults aiming for fat loss need between 60 to 90 grams of high quality protein daily. Protein supports muscle repair and helps maintain lean mass, especially when appetite is reduced.

Strength train consistently. Resistance training at least three to four times a week signals the body to hold onto muscle. Lifting weights, using resistance bands, Pilates, or bodyweight exercises all help.

Do weight bearing cardio. Walking, tennis, or light jogging can support both bone density and muscle retention.

Stay hydrated. Muscle is largely made of water. Dehydration can worsen fatigue and impair recovery.

Aim for slow, steady loss. Losing weight gradually gives the body time to adapt and reduces the risk of excessive muscle breakdown.

Demi Moore’s appearance has reignited a broader conversation about beauty standards, aging, and the pressures surrounding thinness. Regardless of the cause behind her transformation, the moment highlights an important truth. Sustainable health is about strength, balance, and care, not just shrinking numbers on a scale.