Amid Rising Indo-Pak Tensions, Here's How You Can Manage Your Anxiety

Updated May 9, 2025 | 05:00 PM IST

SummaryWhile people on both sides of the border prepare for a possible war, mental health experts have raised concerns about the psychological cost of such a situation.
Amid Rising Indo-Pak Tensions, Here's How You Can Manage Your Anxiety

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India launched massive strikes on terror camps in Pakistan and PoK late night yesterday. The aerial operation came in response to the Pahalgam terror attacks that resulted in 26 people getting killed and several others getting injured last month. As tensions continue to rise in both countries, people in India have been asked to participate in mock drills to prepare for possible emergencies.

While people on both sides of the border prepare for a possible war, mental health experts have raised concerns about the psychological cost of such a situation. They opined that it could result in escalated stress, anxiety and fear. A recent study published in the International Journal of Mental Health Systems earlier this year aunderscored the escalating mental health crisis in Ukraine, exacerbated by the ongoing conflict. The study reveals that prior to the full-scale invasion, approximately 30% of Ukrainians had experienced mental health disorders, with depressive disorders surpassing the EU average. The conflict has severely strained the nation’s mental health infrastructure, underscoring the urgent need for comprehensive reforms and targeted interventions to address the rising rates of anxiety, PTSD, and depression among civilians and displaced populations.

How To Manage Anxiety In Such a Situation, As Per Expert

Dr Shilpi Saraswat, Clinical Psychologist at Sakra World Hospital, Bengaluru, recommends avoiding unnecessary exposure to news and staying in a supportive social circle when stuck in such situations. Here are a few steps you should follow:

1. Limit news exposure: Set boundaries on news consumption to avoid excessive exposure.

2. Stay informed, not overwhelmed: Focus on credible sources and updates rather than constant coverage.

3. Practice self-care: Engage in activities that promote relaxation and stress reduction, such as exercise, meditation, or hobbies.

4. Social support: Connect with loved ones, friends, or support groups to share feelings and concerns.

5. Grounding techniques: Use mindfulness exercises, deep breathing, or physical activity to stay present and focused.

Coping Strategies For Families And Children

If you are someone who resides with the elderly and children, Dr Saraswat recommends having an open discussion with them on the current situation. "Encourage honest discussions about feelings and concerns," he said. Moreover, you must provide reassurance and comfort to them. To avoid anxieties, it is also advised to maintain regular routines and activities to provide a sense of stability. You should also acknowledge and validate children's feelings, helping them process emotions. Moreover, monitor and limit children's exposure to news and media coverage.

Differentiating Normal Stress Responses from Serious Mental Health Concerns

1. Normal stress responses: Anxiety, worry, and fear are common reactions to stressful situations.

2. Signs of more serious concerns: Persistent symptoms, such as intrusive thoughts, nightmares, or avoidance behaviours, may indicate PTSD or other mental health concerns.

3. Panic disorders: Recurring panic attacks, persistent fear of having attacks, or avoidance behaviours may indicate a panic disorder.

4. Seek professional help: If symptoms persist or interfere with daily life, consult a mental health professional for guidance and support.

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Trial Shows That Daily Weight Loss Pill Can Cut Body Weight By A Fifth: Which Pills Are More Effective?

Updated Sep 18, 2025 | 09:01 AM IST

SummaryA new trial shows Eli Lilly’s daily pill orforglipron can cut body weight by up to 20% in adults with obesity, offering a more convenient alternative to injections. The study also found improvements in cholesterol and blood pressure. Separately, Eli Lilly said its pill outperformed Novo Nordisk’s oral semaglutide in diabetes patients.
Trial Shows That Daily Weight Loss Pill Can Cut Body Weight By A Fifth: Which Pills Are More Effective?

Credits: Canva, Eli Lilly, Novo Nordisk

A daily pill for weight loss can help people reduce their body weight by as much as a fifth, according to a large clinical trial that researchers say could reshape obesity treatment and make therapies more accessible. The drug, called orforglipron and manufactured by Eli Lilly, works by targeting the same GLP-1 receptors as popular injectable drugs such as Mounjaro and Wegovy.

The study, published in the New England Journal of Medicine and presented at the European Association for the Study of Diabetes meeting in Vienna, followed 3,127 adults with obesity but no diabetes across multiple countries. After 72 weeks, one in five participants taking the pill lost 20% or more of their body weight, a result health experts are calling a potential breakthrough.

Also Read: Eli Lilly Sends Weight-Loss Pill For Approval: Is Oral GLP-1 As Effective As The Injections?

How Orforglipron Works

Orforglipron belongs to the class of GLP-1 receptor agonists, medications that lower blood sugar, slow digestion, and suppress appetite. These drugs mimic hormones naturally released in the gut, signaling to the brain a feeling of fullness.

While injectable GLP-1 drugs have been hailed as transformative, a pill version is seen as a “holy grail” because it is easier to store, distribute, and take, reducing the barriers to treatment. Pills are also expected to be cheaper than weekly injections, widening access for millions.

Results of the 72-Week Trial

Participants were randomly assigned to receive different daily doses of orforglipron, ranging from 6 mg to 36 mg, or a placebo. All had a body mass index (BMI) of 30 or higher.

Average weight loss:

  • 7.5% with the lowest dose (6 mg)
  • 11.2% with the highest dose (36 mg)

Proportion of patients with major weight reduction on 36 mg:

  • 54.6% lost at least 10% of body weight
  • 36% lost at least 15%
  • 18.4% lost at least 20%

Beyond weight reduction, the study noted improvements in blood pressure, waist circumference, and cholesterol levels. Side effects were mostly gastrointestinal, such as nausea and diarrhea, and were generally mild to moderate.

Lead researcher Dr. Sean Wharton of McMaster University said:

“This could mean an expansion of obesity interventions to groups who are currently excluded due to the cost of and lack of access to injectable medications.”

Why the Pill Matters

The rise of GLP-1 drugs has already begun to reshape obesity and diabetes treatment. But injections create added costs and logistical hurdles for health services. A pill that achieves similar results could be a turning point for how obesity is managed globally.

Experts stress, however, that while the pill’s results are promising, it is not yet approved by the FDA or other global regulators. Eli Lilly has said it expects strong demand once it launches, potentially within the next year.

Eli Lilly vs Novo Nordisk

The trial’s publication coincides with another headline-making announcement: Eli Lilly reported that orforglipron outperformed rival Novo Nordisk’s oral drug, oral semaglutide (Rybelsus), in Novo Nordisk's own head-to-head study on Type 2 diabetes patients.

Blood sugar control at 52 weeks:

  • Orforglipron (36 mg): 2.2% reduction in HbA1c
  • Oral semaglutide (14 mg): 1.4% reduction

Weight loss:

  • Orforglipron: average 9.2% (19.7 pounds)
  • Oral semaglutide: average 5.3% (11 pounds)

When including all patients regardless of discontinuation, weight loss with orforglipron was 8.2% compared to 5.3% with oral semaglutide.

Eli Lilly’s chief scientific officer Dan Skovronsky said the pill could serve as “the main medicine” for patients needing both diabetes and obesity management. Independent experts have also praised the results. Dr. Michael Weintraub of NYU Langone noted the pill’s blood sugar control is “impressive not only compared to other oral medications but also injectables.”

Caveats and Next Steps

Despite the strong results, analysts caution against declaring a clear winner in the oral weight-loss pill race. Novo Nordisk is awaiting FDA approval for a 25 mg version of oral semaglutide for obesity and has tested a 50 mg dose. Higher doses could narrow or close the gap between the two companies.

Dr. Jaime Almandoz of UT Southwestern Medical Center said:

“It’s a little too early to say that one is the leader in this class. But having head-to-head data helps doctors make better decisions for patients.”

Eli Lilly says it plans to apply for regulatory approval of orforglipron for diabetes in 2026, with a global launch expected as early as next year. Detailed results from its head-to-head study will be presented at an upcoming medical meeting.

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5 Eye Symptoms That Might Signal Kidney Issues

Health and Me

Updated Sep 18, 2025 | 03:00 AM IST

SummaryYour eyes could provide an early warning that your kidneys are not functioning properly. While kidney disease is often associated with fatigue, swelling, or changes in urination, it can also show up in your vision. We spoke with a health expert to learn more. Keep reading to know more details.
5 Eye Symptoms That Might Signal Kidney Issues

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Your eyes could be giving you clues that your kidneys aren’t working the way they should. While most people associate kidney trouble with tiredness, swelling, or changes in urination, the effects can also show up in your vision. To understand this better, we spoke with Dr Manoj K. Singhal, Principal Director of Nephrology and Kidney Transplantation at Max Super Speciality Hospital, Vaishali.

5 Eye Symptoms Linked to Kidney Issues

The kidneys filter toxins and help maintain balance in the body. But when they start to weaken, some of the earliest signs may appear in unexpected places, like your eyes. Some of these symptoms, as per Dr Manoj are:

1. Persistent Puffiness

It’s normal to wake up with puffy eyes, but if the swelling doesn’t fade even after rest, it could point to protein leaking into your urine, a condition called proteinuria, which often signals kidney damage.

2. Blurred or Double Vision

Sudden blurriness may be tied to high blood pressure or diabetes—two major causes of kidney problems. These conditions damage small blood vessels in the eyes and can even lead to sudden vision loss.

3. Dry, Itchy Eyes

Many people with chronic kidney disease, especially those on dialysis, experience dryness or irritation in the eyes. This happens when mineral balance in the body is disrupted, leaving the eyes feeling gritty or uncomfortable.

ALSO READ: What Is Babesia That Could Block Your Lyme Disease Recovery?

4. Red or Bloodshot Eyes

Frequent redness can be a warning sign of uncontrolled blood pressure or diabetes. In some rare cases, kidney-related conditions like lupus nephritis can also cause eye problems.

5. Difficulty Seeing Colours

Kidney disease can sometimes affect the optic nerve or retina, making it harder to distinguish certain colours, especially shades of blue and yellow.

When To Seek Help?

Not every eye problem points to kidney disease, but if these symptoms persist or worsen, it’s worth getting both your vision and kidney health checked. Routine eye exams can sometimes reveal early warning signs before bigger problems develop.

If you notice changes in your eyesight alongside other symptoms like fatigue, swelling, or urinary changes, don’t ignore them. Catching kidney issues early can make all the difference for both your eye health and your overall well-being.

ALSO READ: COVID-19 Is No Longer One Of The Top 10 Causes Of Death In US, What Diseases Remain In the Updated List

How To Protect Your Kidneys and Eyes

While some kidney issues are unavoidable, there are steps you can take to reduce your risk and protect both your kidney and eye health, as suggested by Dr Manoj:

  • Maintain a Healthy Blood Pressure and Blood Sugar: High blood pressure and diabetes are major risk factors for kidney disease. Regular monitoring and a balanced diet can help keep these in check.
  • Stay Hydrated: Drinking enough water supports kidney function and helps flush out toxins.
  • Eat a Balanced Diet: Focus on fruits, vegetables, whole grains, and lean proteins while limiting salt, processed foods, and excess sugar.
  • Exercise Regularly: Physical activity improves circulation and helps maintain healthy blood pressure, supporting both kidney and eye health.
  • Avoid Smoking and Excess Alcohol: Both can damage blood vessels, increasing the risk of kidney and eye problems.
  • Schedule Regular Checkups: Routine blood tests, urine tests, and eye exams can help catch early signs of kidney issues before they worsen.

Taking care of your overall health is the best way to safeguard your kidneys. and your eyes from long-term damage.

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Harvard Psychologist Lists Careers Linked To Higher Rates Of Suicide: Doctors Maybe At High Risk Themselves

Updated Sep 17, 2025 | 06:52 PM IST

SummaryWe lose more and more people to suicide every year. Being named one of the leading reasons for death, it is a topic that most people shy away from. However, this Harvard doctor says otherwise. In a podcast interview, Dr. Matthew Nock speaks on suicide and people who are at risk for it.

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Suicides are one of the leading causes of death around the world. While it is easy to say that the person who chose to take their lives did it of their own violation, Harvard psychologist Dr. Matthew Nock, explains the other side. “90% of people who try and kill themselves say, I didn't want to die per se. I wanted to escape from seemingly intolerable.” Speaking on the On Purpose podcast with Jay Shetty, Dr. Nock pointed out that the link between work pressure and suicidal thoughts varies by race and ethnicity.

The concerning rise in suicide cases tied to work pressure has fueled a social media conversation about toxic work culture. What was once considered a normal part of the professional grind is now being openly challenged, as people share personal stories of the anxiety, depression, and isolation caused by unhealthy work environments.

What Professions Are At High Risk Of Suicide?

According to Dr. Matthew Nock, certain careers are linked to a higher risk of suicide.

Police Officers

He noted that physicians and police officers are among those at high risk. He mentioned a spike in suicides among New York City police officers, who are predominantly white men, and shared that female police officers, in particular, face a higher risk, even when accounting for factors like age, race, and ethnicity.

According to a 2025 study published in the Police Practice and Research, on average, 21.4 out of every 100,000 officers died by suicide each year.

The study showed that the suicide rate was much higher for male officers (22.7 per 100,000) than for female officers (12.7 per 100,000).

Physicians

Dr. Nock explained that access to means is a significant factor in these high-risk professions, which helps explain why physicians, police officers, and military members have a much higher risk of suicide compared to others.

Another study published in 2024 The BMJ, showed that the number of suicides among doctors has been going down, female doctors are still at a much higher risk than other people.

When looking at all the data, male doctors were found to have a 5% higher risk of suicide compared to the general population.

In a more recent analysis of the last few years, the overall suicide rate for doctors has decreased, which is good news. But even with this improvement, female doctors still have a 24% higher risk than the general public.

Why We Need To Talk More About Suicide

Dr. Nock stresses the importance of openly discussing suicide, particularly in schools. He compared it to fire drills or earthquake preparedness, saying that since 15% of people will experience suicidal thoughts, it's crucial to equip everyone with a safety plan..Dr. Matthew Nock said, "We know that asking about suicide, talking about suicide, does not make people suicidal."

He noted that the people who act on suicidal thoughts often show different signs than those who just have the thoughts. While depression is a strong predictor of having suicidal thoughts, other factors like anxiety, aggressiveness, poor behavioral control, and drug or alcohol use are more closely linked to a person actually attempting suicide.

He believes that a small educational module on suicide in health class could help save lives by teaching people what to do if they or someone they know is struggling.

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