Tanya Dutt

Are You At Risk For Early Stroke? Your Blood Type Could Hold The Answer

The blood group you belong to is more than just a marker to match your donation; it may have something telling you about your probability of acquiring certain diseases. A new study published in the Journal of Neurology notes that it can be made an assumption from your blood group by which you are most likely to have an early-onset ischemic stroke at the age under 60. 

Although the factors like genetics, age, and lifestyle are the factors that best contribute to the risk of a stroke, this new research has really shed new light on how blood group can be considered as playing a pivotal role than ever thought.

<h2>How Your <span rel="noindex">Blood Type</span> links to Stroke Risk?</h2>

A study suggests that an independent relationship exists between blood type A and an elevated risk for an early-onset ischemic stroke. Ischemic strokes are the presence of a blood clot in one artery, which causes blockage of blood flow to the brain, and about 90% of all stroke cases. The CDC suggests that in the United States, someone has a stroke every 40 seconds while one person dies from a stroke every 3.5 minutes. 

This new research, hence, opens the possibilities that an earlier incidence of ischemic stroke in youth could be attributed to blood type A.

But it's worth remembering that blood type is just one of hundreds of risk factors, according to co-author Braxton Mitchell, PhD, MPH, a genetic epidemiologist at the University of Maryland School of Medicine. "In the grand scheme of things, it's a much smaller risk factor than others," he said. Other genetic, environmental, and lifestyle factors still determine stroke risk.

<h4>Blood Type A: Strong Link to Early-Onset Stroke</h4>

Study authors conducted a genome-wide association analysis, recruiting nearly 17,000 patients with stroke aged 18 to 59 years from 48 studies and more than 599,000 controls who never had a stroke history. The analysis was aimed at exploring genetic variants throughout the human genome in greater detail.

The ABO blood group possessed genetic differences, and the blood type A was the strongest risk factor for a stroke that occurred early in life. The possibility of having an early onset ischemic stroke was 18% higher among people with blood type A compared to the rest of the blood groups. Such a high risk could be associated with a higher susceptibility to blood coagulation, which is one of the most common causes of ischemic strokes.

On the other hand, individuals with type O blood have a 12% reduced risk of an early-onset stroke compared to other blood types. This is in-line with earlier research that has found people with type O blood are more likely to be at low risk for blood clotting inside their arteries, which could be the reason why their overall risk of having a stroke decreased.

Another blood group-the research looked at blood group B-for which a weak association is found with the onset of early and late stroke. However, the authors indicate that when sex and other risk factors are adjusted, no association between blood group B and increased stroke risk exists. In persons with blood group AB, there is no significant association discovered for having an elevated stroke risk.

While this study points to the effect of blood type, it is important to understand that blood type alone is not a strong predictor of stroke risk. Many other factors are comprised in this, including lifestyle, and most importantly, underlying health conditions. Age is one critical factor. According to the CDC, your risk for stroke doubles with each decade after age 55. 

While strokes are more likely to affect people who are 65 years of age and older, one in seven strokes strikes people aged 15 to 49.

Thirdly, gender another factor that has been related to increased risks of stroke conditions. The female population is more prone to stroke compared to the male population and tends to have a worse outcome in terms of disability and death due to stroke. 

It was recently indicated in the 2022 study that young women aged between 35-45 years had a 44% increased risk of ischemic stroke as compared to men aged between 35-45 years. Perhaps pregnancy or the use of birth control could be some of the factors behind the usual increased risk in women.

While the study does show a genetic element linked to blood type and stroke, other controllable factors are more important risks for stroke. Here are some steps you can take to reduce your total risk:

<strong>1. Control Blood Pressure: </strong>High blood pressure forms one of the most dominant risks for strokes. Control through regular monitoring, medication if required, and lifestyle modifications can prove to reduce this significantly.

<strong>2. Maintain a Healthy Weight:</strong> Being overweight increases the risk of stroke. Anyone can benefit from staying at a healthy weight and living a healthy lifestyle. A balanced diet and regular exercise can help you achieve and maintain a healthy weight and thus minimize your risk for stroke.

<strong>3. Reduce Alcohol Intake and Quit Smoking:</strong> Too much alcohol drinking and smoking are also significant risk factors for stroke. Cutting down on alcohol consumption and quitting smoking would be two very important lifestyle changes for anyone interested in being healthy.

<strong>4. Stay Physically Fit:</strong> Exercise is known to keep the heart healthy, reduce blood pressure, and promote a healthy weight all of which contribute to a decrease chance for stroke.

<strong>5. Monitor Your Cholesterol:</strong> It's a fact that high cholesterol builds up plaques in arteries, thereby increasing the chances of stroke occurrence. Fruits, vegetables, whole grains, and lean proteins are part of a heart-healthy diet that helps keep cholesterol at bay.

This research thus brings forward a new and enlightened perspective of the correlation between blood type and stroke risk, especially in younger ages. Although type A blood might have a propensity for developing early ischemic stroke, it is worth noting that this is just one of many factors responsible for developing a stroke. 

Focusing on controllable lifestyle factors such as remaining within a healthy weight range, staying active, and managing blood pressure will help significantly reduce the chances of having a stroke regardless of the blood type.

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The blood group you belong to is more than just a marker to match your donation; it may have something telling you about your probability of acquiring certain diseases. A new study published in the Journal of Neurology notes that it can be made an assumption from your blood group by which you are most likely to have an early-onset ischemic stroke at the age under 60. Although the factors like genetics, age, and lifestyle are the factors that best contribute to the risk of a stroke, this new research has really shed new light on how blood group can be considered as playing a pivotal role than ever thought.How Your Blood Type links to Stroke Risk?A study suggests that an independent relationship exists between blood type A and an elevated risk for an early-onset ischemic stroke. Ischemic strokes are the presence of a blood clot in one artery, which causes blockage of blood flow to the brain, and about 90% of all stroke cases. The CDC suggests that in the United States, someone has a stroke every 40 seconds while one person dies from a stroke every 3.5 minutes. This new research, hence, opens the possibilities that an earlier incidence of ischemic stroke in youth could be attributed to blood type A.But it's worth remembering that blood type is just one of hundreds of risk factors, according to co-author Braxton Mitchell, PhD, MPH, a genetic epidemiologist at the University of Maryland School of Medicine. "In the grand scheme of things, it's a much smaller risk factor than others," he said. Other genetic, environmental, and lifestyle factors still determine stroke risk.Blood Type A: Strong Link to Early-Onset StrokeStudy authors conducted a genome-wide association analysis, recruiting nearly 17,000 patients with stroke aged 18 to 59 years from 48 studies and more than 599,000 controls who never had a stroke history. The analysis was aimed at exploring genetic variants throughout the human genome in greater detail.The ABO blood group possessed genetic differences, and the blood type A was the strongest risk factor for a stroke that occurred early in life. The possibility of having an early onset ischemic stroke was 18% higher among people with blood type A compared to the rest of the blood groups. Such a high risk could be associated with a higher susceptibility to blood coagulation, which is one of the most common causes of ischemic strokes.Blood Type O: Lower Stroke RiskOn the other hand, individuals with type O blood have a 12% reduced risk of an early-onset stroke compared to other blood types. This is in-line with earlier research that has found people with type O blood are more likely to be at low risk for blood clotting inside their arteries, which could be the reason why their overall risk of having a stroke decreased.Blood Type B and AB: Mixed BagAnother blood group-the research looked at blood group B-for which a weak association is found with the onset of early and late stroke. However, the authors indicate that when sex and other risk factors are adjusted, no association between blood group B and increased stroke risk exists. In persons with blood group AB, there is no significant association discovered for having an elevated stroke risk.Other Risk FactorsWhile this study points to the effect of blood type, it is important to understand that blood type alone is not a strong predictor of stroke risk. Many other factors are comprised in this, including lifestyle, and most importantly, underlying health conditions. Age is one critical factor. According to the CDC, your risk for stroke doubles with each decade after age 55. While strokes are more likely to affect people who are 65 years of age and older, one in seven strokes strikes people aged 15 to 49.Thirdly, gender another factor that has been related to increased risks of stroke conditions. The female population is more prone to stroke compared to the male population and tends to have a worse outcome in terms of disability and death due to stroke. It was recently indicated in the 2022 study that young women aged between 35-45 years had a 44% increased risk of ischemic stroke as compared to men aged between 35-45 years. Perhaps pregnancy or the use of birth control could be some of the factors behind the usual increased risk in women.Ways You Can Manage Stroke RiskWhile the study does show a genetic element linked to blood type and stroke, other controllable factors are more important risks for stroke. Here are some steps you can take to reduce your total risk:1. Control Blood Pressure: High blood pressure forms one of the most dominant risks for strokes. Control through regular monitoring, medication if required, and lifestyle modifications can prove to reduce this significantly.2. Maintain a Healthy Weight: Being overweight increases the risk of stroke. Anyone can benefit from staying at a healthy weight and living a healthy lifestyle. A balanced diet and regular exercise can help you achieve and maintain a healthy weight and thus minimize your risk for stroke.3. Reduce Alcohol Intake and Quit Smoking: Too much alcohol drinking and smoking are also significant risk factors for stroke. Cutting down on alcohol consumption and quitting smoking would be two very important lifestyle changes for anyone interested in being healthy.4. Stay Physically Fit: Exercise is known to keep the heart healthy, reduce blood pressure, and promote a healthy weight all of which contribute to a decrease chance for stroke. 5. Monitor Your Cholesterol: It's a fact that high cholesterol builds up plaques in arteries, thereby increasing the chances of stroke occurrence. Fruits, vegetables, whole grains, and lean proteins are part of a heart-healthy diet that helps keep cholesterol at bay.This research thus brings forward a new and enlightened perspective of the correlation between blood type and stroke risk, especially in younger ages. Although type A blood might have a propensity for developing early ischemic stroke, it is worth noting that this is just one of many factors responsible for developing a stroke. Focusing on controllable lifestyle factors such as remaining within a healthy weight range, staying active, and managing blood pressure will help significantly reduce the chances of having a stroke regardless of the blood type.

are you at risk for early stroke? your blood type could hold the answer

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It’s easy to assume that serious health risks are a concern for later in life. For most young men in their 20s and 30s, long-term health is something they discuss in relation to staying fit, maintaining a balance between job and life, and remaining active. But behind the scenes, there's a silent danger brewing that doesn't carry vehement warning signs or agonizing symptoms, yet is increasing amongst this demographic. And shockingly, nearly 90% of young men don't even know they might be impacted. The truth is, being attuned to your body now might save your life down the road. Here's why medical professionals are urging young men to listen up.

Roughly 10,000 new instances of testicular cancer are diagnosed annually in the United States, according to the American Cancer Society, with an average age of diagnosis of only 33. Unlike the majority of the other cancers that occur later in life, this cancer comes early—most commonly between 20 and 40 years of age.

However, only 13% of the American adults polled recognized that testicular cancer is more frequent among young men and thus ranks as one of the most underappreciated dangers in young adult male health.

Testicular cancer is not only uncommon; it's not well understood. "From my experience, many men are surprised testicular cancer is most prevalent among young men," adds Dr. Shawn Dason, an Ohio State urologist and lead author of the study. "You're just not expecting it in your thirties or twenties."

In contrast to certain types of cancer with sets of initial warning signs, testicular cancer tends to be painless and thus more difficult to notice through sheer habit. The consequence? Late-stage diagnoses that lower survival rates.

Though survival after five years is 95% if caught early, this drops to 73% if the condition becomes widespread beyond the testicle. Despite the high cure rate, however, just 35% of survey respondents thought screening under age 40 is required.

Adding to the threat is that the symptoms—if any—are insidious:

<ul><li>A bulge or lump in the scrotum</li><li>Heaviness or discomfort</li><li>Change in size or firmness of a testicle</li><li>Pain or tenderness not caused by injury</li></ul>

Far too frequently, these symptoms are overlooked, dismissed, or go unnoticed because of the lack of overall awareness.

<h2>Why Testicular Cancer Affects Younger Men?</h2>

The reason why testicular cancer so heavily strikes younger men is still being researched, but it is thought to be attributed to germ cell activity, which is greater at a man's reproductive prime. These germ cells, used to make sperm, can become mutated and give rise to tumors.

<ul><li>Family history of testicular cancer</li><li>White ethnicity</li><li>Being tall (according to some research)</li><li>Having undescended testicles (cryptorchidism)</li></ul>

And, for some reason, being overweight hasn't proved to be a major risk factor—despite its link with so many other cancers.

A 2024 study from California found testicular cancer rates in men under 39 increased by 10% over two decades, climbing from 6 to 7.3 cases per 100,000 people. According to the CDC, national figures mirrored the trend, with an increase from 6.3 to 6.8 cases per 100,000 men aged 0–39 between 1999 and 2021.

Experts credit this increase to enhanced screening and environmental or lifestyle factors possibly impacting the development of germ cell tumors in young men.

Early detection is a good thing—and it starts at home. The Testicular Cancer Foundation advises a monthly self-exam, preferably after a warm shower when scrotal skin is soft.

<h2>How to Do a Testicular Self-Exam</h2>

STEP 1- Visually check for swelling, asymmetry, or change.

STEP 2- Gently explore each testicle with thumb and fingers.

STEP 3- Check for lumps, hard spots, or rapid change in size, weight, or texture.

STEP 4- Check for pain, heaviness, or tenderness.

If you find anything abnormal, consult a doctor at once—ideally a urologist. You might be sent for an ultrasound or blood test.

Even with this easy and possibly life-saving measure, only 54% of men were aware they need to perform monthly self-exams, according to the Ohio State study—and the number that actually do so is probably much less.

The majority of testicular cancers are treated successfully, particularly if diagnosed early. The initial course of treatment is surgery, where the cancerous testicle is surgically removed. This surgery, an orchiectomy, is usually followed by:

<ul><li>Surveillance (routine check-ups if detected early)</li><li>Radiation or chemotherapy (for late stages)</li><li>Lymph node removal if cancer spreads</li></ul>

Most men continue to have healthy, active lives after treatment, such as professional athletes Nathan Adrian, an Olympic swimmer, and cyclist Lance Armstrong. Both were diagnosed in their 20s and underwent successful treatment following early detection.

<h2>Why It is Important to Prioritize Men's Preventive Health?</h2>

The larger concern is not testicular cancer—but men's overall attitude towards their health. Men under age 40 typically avoid preventive care, letting career pressure and everyday life interfere.

Dr. Dason places a premium on mindset change: "We need to make health check-ups and being aware of one's body 'normal' among men in their 20s and 30s. Waiting for symptoms is waiting too long."

Awareness is your most powerful ally in the fight against testicular cancer. If you’re a young man—or know one—start talking about this. Normalize self-exams, reduce stigma, and encourage open conversations with healthcare providers because when caught early, testicular cancer is not just treatable—it’s beatable.

men's health month

cancer in young men

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It’s easy to assume that serious health risks are a concern for later in life. For most young men in their 20s and 30s, long-term health is something they discuss in relation to staying fit, maintaining a balance between job and life, and remaining active. But behind the scenes, there's a silent danger brewing that doesn't carry vehement warning signs or agonizing symptoms, yet is increasing amongst this demographic. And shockingly, nearly 90% of young men don't even know they might be impacted. The truth is, being attuned to your body now might save your life down the road. Here's why medical professionals are urging young men to listen up.Roughly 10,000 new instances of testicular cancer are diagnosed annually in the United States, according to the American Cancer Society, with an average age of diagnosis of only 33. Unlike the majority of the other cancers that occur later in life, this cancer comes early—most commonly between 20 and 40 years of age.However, only 13% of the American adults polled recognized that testicular cancer is more frequent among young men and thus ranks as one of the most underappreciated dangers in young adult male health.Testicular cancer is not only uncommon; it's not well understood. "From my experience, many men are surprised testicular cancer is most prevalent among young men," adds Dr. Shawn Dason, an Ohio State urologist and lead author of the study. "You're just not expecting it in your thirties or twenties."In contrast to certain types of cancer with sets of initial warning signs, testicular cancer tends to be painless and thus more difficult to notice through sheer habit. The consequence? Late-stage diagnoses that lower survival rates.Symptoms of Testicular CancerThough survival after five years is 95% if caught early, this drops to 73% if the condition becomes widespread beyond the testicle. Despite the high cure rate, however, just 35% of survey respondents thought screening under age 40 is required.Adding to the threat is that the symptoms—if any—are insidious:A bulge or lump in the scrotumHeaviness or discomfortChange in size or firmness of a testiclePain or tenderness not caused by injuryFar too frequently, these symptoms are overlooked, dismissed, or go unnoticed because of the lack of overall awareness.Why Testicular Cancer Affects Younger Men?The reason why testicular cancer so heavily strikes younger men is still being researched, but it is thought to be attributed to germ cell activity, which is greater at a man's reproductive prime. These germ cells, used to make sperm, can become mutated and give rise to tumors.Some of the risk factors are:Family history of testicular cancerWhite ethnicityBeing tall (according to some research)Having undescended testicles (cryptorchidism)And, for some reason, being overweight hasn't proved to be a major risk factor—despite its link with so many other cancers.A 2024 study from California found testicular cancer rates in men under 39 increased by 10% over two decades, climbing from 6 to 7.3 cases per 100,000 people. According to the CDC, national figures mirrored the trend, with an increase from 6.3 to 6.8 cases per 100,000 men aged 0–39 between 1999 and 2021.Experts credit this increase to enhanced screening and environmental or lifestyle factors possibly impacting the development of germ cell tumors in young men.Early detection is a good thing—and it starts at home. The Testicular Cancer Foundation advises a monthly self-exam, preferably after a warm shower when scrotal skin is soft.How to Do a Testicular Self-ExamSTEP 1- Visually check for swelling, asymmetry, or change.STEP 2- Gently explore each testicle with thumb and fingers.STEP 3- Check for lumps, hard spots, or rapid change in size, weight, or texture.STEP 4- Check for pain, heaviness, or tenderness.If you find anything abnormal, consult a doctor at once—ideally a urologist. You might be sent for an ultrasound or blood test.Even with this easy and possibly life-saving measure, only 54% of men were aware they need to perform monthly self-exams, according to the Ohio State study—and the number that actually do so is probably much less.What Happens After Diagnosis?The majority of testicular cancers are treated successfully, particularly if diagnosed early. The initial course of treatment is surgery, where the cancerous testicle is surgically removed. This surgery, an orchiectomy, is usually followed by:Surveillance (routine check-ups if detected early)Radiation or chemotherapy (for late stages)Lymph node removal if cancer spreadsMost men continue to have healthy, active lives after treatment, such as professional athletes Nathan Adrian, an Olympic swimmer, and cyclist Lance Armstrong. Both were diagnosed in their 20s and underwent successful treatment following early detection.Why It is Important to Prioritize Men's Preventive Health?The larger concern is not testicular cancer—but men's overall attitude towards their health. Men under age 40 typically avoid preventive care, letting career pressure and everyday life interfere.Dr. Dason places a premium on mindset change: "We need to make health check-ups and being aware of one's body 'normal' among men in their 20s and 30s. Waiting for symptoms is waiting too long."Awareness is your most powerful ally in the fight against testicular cancer. If you’re a young man—or know one—start talking about this. Normalize self-exams, reduce stigma, and encourage open conversations with healthcare providers because when caught early, testicular cancer is not just treatable—it’s beatable.

90% of young men in their 20s and 30s are unaware of this fast-rising cancer threat

Ishita Roy

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Cervical cancer, though almost entirely preventable, continues to claim over 350,000 lives each year — most of them women in developing countries. India carries one of the heaviest burdens. But it doesn’t have to be this way. Science has handed us the tools — vaccines, DNA-based screening, and effective treatments. The real hurdle? Making sure these solutions reach everyone, regardless of gender, geography, or income.

<h4>Understanding <span rel="noindex">HPV</span>: The Root Cause</h4>

At the heart of the cervical cancer crisis is the <span>Human Papillomavirus</span> (HPV), one of the most common sexually transmitted infections worldwide. Most HPV infections resolve on their own. But when certain high-risk genotypes persist, they can lead to various cancers — not just cervical, but also anal, penile, vulvar, vaginal, and oropharyngeal.

According to the World Health Organization (WHO), virtually all cervical cancer cases are caused by HPV. Every eight minutes, a woman in India dies of this disease — a stark statistic for something that could be prevented with timely vaccination and screening.

<h4>HPV Affects Men Too — And We’re Ignoring It</h4>

While cervical cancer has gained some attention, HPV-related cancers in men remain dangerously underdiagnosed. In 2019 alone, over 70,000 cancer cases in men were caused by HPV — a number many experts say is underestimated.

This was underscored by a recent study presented at the 10th Asia Pacific AIDS and Co-Infections Conference in Japan. Conducted by Dr Prapti Gilada-Toshinwal at a Mumbai clinic, it screened 105 men who have sex with men. The findings were worrying — 62% had anal HPV infections, rising to nearly 69% among those living with HIV. Many were also battling other sexually transmitted infections, pointing to an urgent need for integrated sexual health services.

<h4>Why DNA Screening is a Gamechanger</h4>

Globally, experts agree that the best way to detect HPV is through DNA-based molecular tests. Traditional screening methods like Pap smears or VIA (Visual Inspection with Acetic Acid) are no longer considered scientifically adequate.

Yet, India’s most recent National Family Health Survey revealed that only 1.2% of women aged 15–49 had ever been screened for cervical cancer. WHO recommends that 70% of eligible women should be screened — a target India is far from achieving.

In a promising development, April 2025 saw the validation of Truenat HPV-HR Plus, India’s first indigenous point-of-care HPV DNA test. Developed by Molbio Diagnostics and approved by leading institutions like AIIMS Delhi and ICMR’s research bodies, Truenat can detect eight high-risk HPV genotypes responsible for most cervical cancers. It’s fast, affordable, and adaptable for rural clinics — exactly the kind of innovation needed to scale up screening access.

<h4>The Vaccine That Works — Even in a Single Dose</h4>

Vaccination remains our most powerful tool. A WHO-IARC study, led in part by Indian researcher Dr Smita Joshi, revealed that even one dose of the HPV vaccine offers strong protection. This has led to WHO recommending a single-dose vaccine schedule for young girls.

India’s own vaccine, Ceravac, developed by the Serum Institute, is approved for boys as well. Yet, a national rollout remains pending, even as a few states like Delhi and Punjab have begun pilot programs.

Activists like Vijay Nair of Udaan Trust stress the need to include men in both vaccination and screening programs. Anal cancers are often missed or misdiagnosed in men, especially those from marginalized communities. Without proper diagnostic facilities like anoscopy centres and broader awareness, many are left untreated — or worse, undiagnosed.

The WHO has set ambitious targets to eliminate cervical cancer: vaccinate 90% of girls by age 15, screen 70% of women by 35 and 45, and treat 90% of cases. But meeting these goals demands more than science — it needs political will, public funding, and sustained awareness.

human papillomavirus

health and wellness

men have HPV

HPV disease

Cervical cancer, though almost entirely preventable, continues to claim over 350,000 lives each year — most of them women in developing countries. India carries one of the heaviest burdens. But it doesn’t have to be this way. Science has handed us the tools — vaccines, DNA-based screening, and effective treatments. The real hurdle? Making sure these solutions reach everyone, regardless of gender, geography, or income.Understanding HPV: The Root CauseAt the heart of the cervical cancer crisis is the Human Papillomavirus (HPV), one of the most common sexually transmitted infections worldwide. Most HPV infections resolve on their own. But when certain high-risk genotypes persist, they can lead to various cancers — not just cervical, but also anal, penile, vulvar, vaginal, and oropharyngeal.According to the World Health Organization (WHO), virtually all cervical cancer cases are caused by HPV. Every eight minutes, a woman in India dies of this disease — a stark statistic for something that could be prevented with timely vaccination and screening.HPV Affects Men Too — And We’re Ignoring ItWhile cervical cancer has gained some attention, HPV-related cancers in men remain dangerously underdiagnosed. In 2019 alone, over 70,000 cancer cases in men were caused by HPV — a number many experts say is underestimated.This was underscored by a recent study presented at the 10th Asia Pacific AIDS and Co-Infections Conference in Japan. Conducted by Dr Prapti Gilada-Toshinwal at a Mumbai clinic, it screened 105 men who have sex with men. The findings were worrying — 62% had anal HPV infections, rising to nearly 69% among those living with HIV. Many were also battling other sexually transmitted infections, pointing to an urgent need for integrated sexual health services.Why DNA Screening is a GamechangerGlobally, experts agree that the best way to detect HPV is through DNA-based molecular tests. Traditional screening methods like Pap smears or VIA (Visual Inspection with Acetic Acid) are no longer considered scientifically adequate.Yet, India’s most recent National Family Health Survey revealed that only 1.2% of women aged 15–49 had ever been screened for cervical cancer. WHO recommends that 70% of eligible women should be screened — a target India is far from achieving.A Made-in-India BreakthroughIn a promising development, April 2025 saw the validation of Truenat HPV-HR Plus, India’s first indigenous point-of-care HPV DNA test. Developed by Molbio Diagnostics and approved by leading institutions like AIIMS Delhi and ICMR’s research bodies, Truenat can detect eight high-risk HPV genotypes responsible for most cervical cancers. It’s fast, affordable, and adaptable for rural clinics — exactly the kind of innovation needed to scale up screening access.The Vaccine That Works — Even in a Single DoseVaccination remains our most powerful tool. A WHO-IARC study, led in part by Indian researcher Dr Smita Joshi, revealed that even one dose of the HPV vaccine offers strong protection. This has led to WHO recommending a single-dose vaccine schedule for young girls.India’s own vaccine, Ceravac, developed by the Serum Institute, is approved for boys as well. Yet, a national rollout remains pending, even as a few states like Delhi and Punjab have begun pilot programs.Prevention Must Be InclusiveActivists like Vijay Nair of Udaan Trust stress the need to include men in both vaccination and screening programs. Anal cancers are often missed or misdiagnosed in men, especially those from marginalized communities. Without proper diagnostic facilities like anoscopy centres and broader awareness, many are left untreated — or worse, undiagnosed.The WHO has set ambitious targets to eliminate cervical cancer: vaccinate 90% of girls by age 15, screen 70% of women by 35 and 45, and treat 90% of cases. But meeting these goals demands more than science — it needs political will, public funding, and sustained awareness.

Aarushi Bhadury

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Lower back pain is a constant issue for many people. While it may seem like a minor inconvenience to some, it can severely impact their quality of life. For people who are suffering from ongoing back pain, finding relief can be incredibly challenging. 

While there are medications available, there are side-effects one must consider. However, new research suggests that two types of therapy might offer a promising solution, especially for those who have been relying on opioid medications. 

<h2>Therapies Show Promise for Opioid Users </h2>

A study published April 7 in JAMA Network Open found that mindfulness-based therapy (MBT) and cognitive behavioral therapy (CBT) significantly improved the quality of life for people managing chronic low back pain with opioids. Participants reported less pain and were able to reduce their opioid dosages in the months following the start of these therapies. 

Researchers noted that the participants had lived with moderate to severe back pain for a long time, most for over five years, and had tried many other treatments without success. The improvements seen were therefore even more significant. 

<h2>Addressing a Common and Stubborn Problem </h2>

Chronic low back pain affects a large number of people; data suggests that as many as 28% of Americans experience it. Despite its prevalence, effective treatments are often hard to come by. One study in March found that only 10% of non-surgical treatments for lower back pain actually work. This led researchers to explore whether CBT and MBT could offer a better approach. 

<strong>Cognitive Behavioral Therapy (CBT) </strong>helps patients identify negative thoughts and behaviors, then uses problem-solving and self-reflection to change those patterns. 

<strong>Mindfulness-Based Therapy (MBT) </strong>teaches people to observe their bodily sensations, feelings, and thoughts without reacting to them, often through meditation to focus on the present moment. 

<h2>Promising Results from the Study </h2>

The study involved 770 adults who were using opioids for their chronic low back pain. On average, participants were about 58 years old and experienced moderate-to-severe pain, limitations in their daily activities, and a reduced quality of life.

Half of the participants received CBT, and the other half received MBT. They attended weekly two-hour group sessions for eight weeks. After this, they were encouraged to practice what they learned for 30 minutes daily, six days a week, for the remainder of the 12-month study. Although about 30% of participants dropped out by the six-month mark, those who continued reported: 

<ul><li>Less pain.</li><li>Reduced daily opioid use.</li><li>Better daily function.</li><li>Improved quality of life.</li></ul>

These benefits lasted throughout the year, with over 65% of participants still reporting progress at the 12-month mark. Dr. Zgierska highlighted that chronic back pain usually doesn't get better on its own, often worsening over time, which makes these lasting improvements particularly striking. Since both therapies showed similar positive results, people can confidently choose the approach that best suits them, whether it's the structured nature of CBT or the mindfulness focus of MBT. Both in-person and online formats were found to be effective. 

<h2>Supporting Evidence and Future Needs </h2>

While this JAMA Network Open study didn't include a control group or have much racial and ethnic diversity among its participants, its findings align with other research suggesting that behavioral therapies can help adults using opioids for chronic pain. 

It's important to note that this area still needs more research. Only 17 studies have looked at MBT for chronic low back pain, and only three have directly compared it to CBT. However, previous studies have shown that both MBT and CBT are generally effective for pain relief, even if they haven't always included people on opioids for chronic back pain. The fact that this new research shows they help in more severe cases (with opioid use) further strengthens these findings. 

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Lower back pain is a constant issue for many people. While it may seem like a minor inconvenience to some, it can severely impact their quality of life. For people who are suffering from ongoing back pain, finding relief can be incredibly challenging. While there are medications available, there are side-effects one must consider. However, new research suggests that two types of therapy might offer a promising solution, especially for those who have been relying on opioid medications. Therapies Show Promise for Opioid Users A study published April 7 in JAMA Network Open found that mindfulness-based therapy (MBT) and cognitive behavioral therapy (CBT) significantly improved the quality of life for people managing chronic low back pain with opioids. Participants reported less pain and were able to reduce their opioid dosages in the months following the start of these therapies. Researchers noted that the participants had lived with moderate to severe back pain for a long time, most for over five years, and had tried many other treatments without success. The improvements seen were therefore even more significant. Addressing a Common and Stubborn Problem Chronic low back pain affects a large number of people; data suggests that as many as 28% of Americans experience it. Despite its prevalence, effective treatments are often hard to come by. One study in March found that only 10% of non-surgical treatments for lower back pain actually work. This led researchers to explore whether CBT and MBT could offer a better approach. Cognitive Behavioral Therapy (CBT) helps patients identify negative thoughts and behaviors, then uses problem-solving and self-reflection to change those patterns. Mindfulness-Based Therapy (MBT) teaches people to observe their bodily sensations, feelings, and thoughts without reacting to them, often through meditation to focus on the present moment. Promising Results from the Study The study involved 770 adults who were using opioids for their chronic low back pain. On average, participants were about 58 years old and experienced moderate-to-severe pain, limitations in their daily activities, and a reduced quality of life.Half of the participants received CBT, and the other half received MBT. They attended weekly two-hour group sessions for eight weeks. After this, they were encouraged to practice what they learned for 30 minutes daily, six days a week, for the remainder of the 12-month study. Although about 30% of participants dropped out by the six-month mark, those who continued reported: Less pain.Reduced daily opioid use.Better daily function.Improved quality of life.These benefits lasted throughout the year, with over 65% of participants still reporting progress at the 12-month mark. Dr. Zgierska highlighted that chronic back pain usually doesn't get better on its own, often worsening over time, which makes these lasting improvements particularly striking. Since both therapies showed similar positive results, people can confidently choose the approach that best suits them, whether it's the structured nature of CBT or the mindfulness focus of MBT. Both in-person and online formats were found to be effective. Supporting Evidence and Future Needs While this JAMA Network Open study didn't include a control group or have much racial and ethnic diversity among its participants, its findings align with other research suggesting that behavioral therapies can help adults using opioids for chronic pain. It's important to note that this area still needs more research. Only 17 studies have looked at MBT for chronic low back pain, and only three have directly compared it to CBT. However, previous studies have shown that both MBT and CBT are generally effective for pain relief, even if they haven't always included people on opioids for chronic back pain. The fact that this new research shows they help in more severe cases (with opioid use) further strengthens these findings. 

easing chronic lower back pain and painkiller usage with 2 therapies

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