On October 5, 2025, leading reproductive health organisations released new guidelines aimed at transforming how postpartum hemorrhage (PPH) is prevented, diagnosed, and treated. The World Health Organization (WHO), along with the International Federation of Gynecology and Obstetrics and the International Confederation of Midwives, released the new guidelines introducing objective criteria to help identify primary postpartum hemorrhage earlier.

WHO Releases New Guidelines For Postpartum Hemorrhage

According to the researchers, even blood loss below the traditional threshold, when accompanied by abnormal vital signs, can indicate a high risk of life-threatening complications. Traditionally, PPH was defined as blood loss of 500 mL or more. The new guidelines suggest that losses of 300 mL or less, when paired with warning signs, should trigger immediate intervention. Early recognition, they note, could save countless lives.

PPH, or excessive bleeding after childbirth, remains a leading cause of maternal deaths worldwide. In 2023, roughly 45,000 out of 260,000 maternal deaths were linked to PPH. While strategies to prevent and manage PPH exist, their application has often been inconsistent. These updated guidelines aim to provide clear, evidence-based guidance that can inform national and local health policies, clinical protocols, and programmatic strategies.

New Guidelines For Postpartum Hemorrhage

The document consolidates 51 recommendations covering prevention, diagnosis, treatment, supportive care, and health system measures. It also emphasises rapid intervention using the E-MOTIVE bundle, which includes:

• Uterine massage
• Oxytocic drugs to stimulate contractions
• Tranexamic acid to control bleeding
• Intravenous fluids
• Examination of the vagina and genital tract
• Escalation of care if bleeding continues

In rare cases where bleeding persists, the guidelines advise measures such as surgery or blood transfusion to stabilize women until further treatment can be provided.

Alongside the guidelines, WHO and partners, including the United Nations Population Fund have developed training and implementation resources. These tools are designed for frontline health workers, offering practical guidance, simulation-based emergency response training, and materials to help implement best practices at national and sub-national levels.

Jeremy Farrar, WHO assistant director-general for health promotion and disease prevention, highlighted the purpose of the new guidance: “These guidelines are designed to maximise impact where maternal deaths are highest and resources are limited, helping more women survive childbirth and safely return home to their families.”

The world is currently off track to meet Sustainable Development Goal 3, which seeks a global maternal mortality ratio below 70 per 100,000 live births by 2030. By improving understanding of PPH causes and advancing timely interventions, health systems can save lives and address deep inequalities in maternal health.

From this year onward, October 5 will be observed as World PPH Day, sending a strong message: no woman should die from preventable postpartum hemorrhage. Concerted global efforts to prevent and treat PPH can play a pivotal role in reducing maternal deaths and improving health equity worldwide.

A new study published in The BMJ suggests that women who skip their first mammogram face a higher risk of being diagnosed with advanced breast cancer and dying from the disease. The research, released on September 24, followed over 400,000 women in Sweden for up to 25 years. As October marks Breast Cancer Awareness Month, the findings highlight the importance of early screening.

Skipping the First Mammogram Can Increase Risk

Since the early 1990s, Sweden has offered regular mammography screenings, which have helped reduce breast cancer deaths. Yet, a significant number of women still choose to skip their first appointment. Researchers wanted to understand the long-term impact of missing this initial screening.

The study analyzed data from the Swedish mammography program and national health registries, covering nearly 433,000 women in Stockholm from 1991 to 2020. About 32 percent of women declined their first screening. Those who missed it were also less likely to attend future screenings, often leading to later-stage diagnoses and worse outcomes.

Women who skipped their first mammogram were more likely to be diagnosed with advanced cancer. The risk of developing stage III breast cancer was about 1.5 times higher, and for stage IV, it was 3.6 times higher than among women who attended their first screening.

Over the 25-year follow-up, nearly 1 percent of women who skipped the first mammogram died from breast cancer, compared with 0.7 percent among those who attended—a 40 percent higher mortality risk. Interestingly, the overall rate of breast cancer development was nearly the same in both groups, around 7.7 percent, indicating that the increased deaths were due to delayed detection, not more cases of the disease.

How Mammograms Affect Breast Cancer Risk?

Mammograms use low-dose X-rays to image the breast. While repeated radiation exposure can slightly increase the risk of cancer, the amount of radiation from mammography is minimal. According to the National Cancer Institute (NCI), the risk is most significant when a person undergoes multiple chest X-rays over time.

A 2016 study examined women aged 40 to 74 who received annual or biennial mammograms, noting that repeated exposure could slightly raise cancer risk, particularly for women with larger breasts. However, both that study and more recent reviews conclude that the benefits of regular mammograms far outweigh the risks. Regulatory bodies like the FDA and the Mammography Quality Standards Act ensure that equipment and radiation levels remain within safe limits.

Early detection remains the key: attending the first mammogram can catch breast cancer sooner, improve treatment outcomes, and ultimately save lives.

Lewis Moody: Former England captain Lewis Moody revealed on Monday that he has been diagnosed with Motor Neurone Disease (MND). Moody, 47, retired from professional rugby in 2012 after a remarkable 16-year career that included stints with Leicester Tigers, Bath, England, and the British and Irish Lions. The flanker lifted nearly every trophy available and played in some of the most high-stakes matches in rugby history. With his diagnosis now public, many are asking: are athletes more prone to developing MND?

What Is Motor Neurone Disease?

Motor Neurone Disease is a group of neurological disorders that progressively destroy motor neurons, the nerve cells responsible for controlling voluntary muscle movements such as walking, speaking, swallowing, and even breathing.

Messages from the brain’s upper motor neurons are transmitted to lower motor neurons in the spinal cord, which then communicate with muscles. When these signals fail, muscles begin to weaken and shrink, a process called muscle atrophy. Damage to lower motor neurons can also cause stiffness and overactive reflexes, making voluntary movements slow and difficult. Over time, MND can result in the loss of mobility and the ability to control other bodily movements.

Currently, there is no cure for MND. The disease is progressive and worsens over time, but certain treatments and interventions can help manage symptoms and improve quality of life.

Lewis Moody, Motor Neurone Disease: Are Athletes at Higher Risk?

Recent research suggests there may be a link between contact sports and MND. A 2022 study from the University of Glasgow, which examined 400 former Scotland rugby players, found they had a higher likelihood of developing the condition. Additionally, researchers at Durham University discovered that rugby players who suffered repeated concussions exhibited biological differences that could make them more susceptible to MND.

The MND Association notes that while there is a correlation between contact sports and MND, it does not necessarily mean that playing sports causes the disease. The studies indicate a greater prevalence among athletes, but they stop short of establishing a direct cause-and-effect relationship.

Symptoms of Motor Neurone Disease

MND often begins subtly, with symptoms appearing gradually. Early warning signs can include:

• Weakness in legs or ankles, causing difficulty climbing stairs or frequent tripping
• Slurred speech (dysarthria)
• Trouble swallowing
• Weak grip, making daily tasks like buttoning a shirt or opening jars challenging
• Muscle twitches and cramps
• Weight loss from shrinking arm and leg muscles
• Involuntary laughter or crying at inappropriate times (pseudobulbar affect)

Causes of Motor Neurone Disease

Diagnosing Motor Neurone Disease

There is no single test to diagnose MND. Doctors typically rely on symptom observation and physical examinations. To confirm the diagnosis and rule out other conditions, they may use:

• Electromyography (EMG) and nerve conduction tests
• MRI scans of the brain and spinal cord
• Blood tests
• Muscle biopsies
• Lumbar punctures

There are 3.2 million new cases of colon cancer every year, with a prediction of 1.6 million fatalities each year by 2040, reveals the World Health Organization (WHO). Colorectal cancer or colon cancer is one of the most deadly tumors in the world. Early detection and prophylactic treatment are essential because HPV is currently the second most common cause of cancer-related deaths worldwide.

Why Colonoscopy Matters

Dr. Emmanuel Aguh, who is a US-based physician, highlighted that a simple colonoscopy can actually save lives. The procedure offers direct visualization and real-time imaging of the colon and rectum, enabling doctors to identify abnormalities while they are still treatable.

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“Colonoscopies may sound intimidating, but they can catch colon cancer at its earliest stage, giving patients the best chance of survival. More importantly, the test allows doctors to remove precancerous polyps before they ever turn into cancer,” Dr. Aguh explained in a recent post.

Unlike other diagnostic techniques, a colonoscopy combines detection and prevention. In addition to helping identify current problems, early excision of abnormal growths lowers future dangers.

How to overcome the fear of colonoscopy?

The thought of undergoing a colonoscopy could be scary for some people, as it could trigger anxiety. However, Dr Aguh reassured patients that the procedure is performed under sedation. It makes the process painless.

“The idea of a colonoscopy can be intimidating, but here’s the truth: the procedure itself is done under sedation. You go to sleep, and when you wake up, it’s over. Yes, there may be some temporary discomfort, but it is a small price to pay for something that could save your life,” he explained.

What Happens During a Colonoscopy?

A colonoscopy is a type of endoscopic technique used specifically to examine the large intestine, which includes the colon, rectum, and anus. In the process, an endoscope is used, which is a flexible tube with a lighted camera that is moved across the colon after being cautiously entered through the rectum.

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The device then transmits images of the intestinal lining to a screen as it passes, allowing the clinician to detect polyps, inflammation, bleeding, or abnormal growths. If anomalies are found, the doctor can remove polyps immediately or take tissue samples for further examination.

Since a colonoscopy may detect and cure the disease in a single session, it is a useful preventive measure. Experts caution that colon cancer may develop silently and without symptoms until it reaches an advanced stage. As a result, screening is thought to be the best method of illness prevention.

What is the right time to get a colonoscopy?

Dr. Aguh recommends beginning as early as age 30, especially for those at higher risk.

You may be due for a colonoscopy if you:

• Are over 30 years old and have never had one.
• Have not undergone screening in the past 10 years.
• Had polyps or abnormal tissue removed during a previous colonoscopy.
• Have a family history of colorectal cancer.
• Carry genetic conditions that increase risk, such as Lynch syndrome.
• Suffer from inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis.

Since colorectal cancer often progresses without obvious signs until it is advanced, screening becomes a crucial safeguard, even if you feel healthy.

As Dr. Aguh puts it: “It may feel uncomfortable to think about, but a colonoscopy is a short, safe procedure that can protect you from a disease that claims millions of lives every year. Don’t wait for symptoms, screening is the best step toward saving your life.”