When we hear about blood pressure, it's often in the context of hypertension — the "silent killer" that increases long-term risk for heart attacks and strokes. But there’s another side to the story that can be just as dangerous, if not more immediately deadly. Blood pressure is more than just a pair of numbers on your doctor’s chart—it’s a vital sign of how well your heart and blood vessels are delivering life-sustaining oxygen and nutrients to every organ in your body.

While most people are familiar with the risks of high blood pressure, the dangers of a sudden drop in blood pressure, or acute hypotension, are often underestimated and sometimes misunderstood but can such a drop be fatal? A sudden drop in blood pressure, known as acute hypotension. While occasional dizziness or lightheadedness may seem harmless, in some cases, a rapid decline in blood pressure can trigger a chain reaction that may ultimately result in organ failure or even death.

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What Happens When Blood Pressure Plummets?

Blood pressure is measured as two numbers: systolic (the pressure as your heart beats) and diastolic (the pressure as your heart rests between beats). According to the National Heart, Lung and Blood Institute, a normal reading for healthy adults is under 120/80 mmHg. When blood pressure falls below 90/60 mmHg, it’s considered low, or hypotension.

A sudden decrease—even a drop of just 20 mmHg in systolic pressure—can cause symptoms like dizziness, confusion, and fainting. More severe drops can be catastrophic, as Dr. S.S. Sibia, Cardiologist & Director at Sibia Medical Center Ludhiana, explains, "A sudden loss of blood pressure, or acute hypotension, can actually lead to death. Blood pressure helps deliver oxygen and nutrients to vital organs like the brain, heart, and kidneys. If BP suddenly falls, the body may not be in a state to maintain regular blood flow, leading to severe complications."

What Causes The Blood Pressure To Drop Suddenly?

There are several causes of acute hypotension, and they often intersect. Here are the most common physiological triggers:

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Hypovolemia

Decreased cardiac output

Vasodilation

Hypotensive syndrome

Dr. Yogendra Singh Rajput, Associate Director of Cardiology at Marengo Asia Hospitals, Gurugram, notes, "The most common cause of sudden drop in blood pressure is massive heart attack. Any massive heart attack of right side or a right coronary artery can lead to a sudden drop... ultimately the patient can die." He adds that internal bleeding — such as from a ruptured gastric ulcer — or extreme dehydration from vomiting or loose motions, are other serious culprits.

Symptoms of Sudden Low Blood Pressure

When blood pressure drops quickly, the body doesn't get enough oxygen, especially the brain. That’s why many of the early symptoms are neurologic in nature:

• Dizziness or fainting
• Confusion or disorientation
• Blurred vision
• Lightheadedness
• Heart palpitations
• Cold, clammy skin
• Headache
• Rapid breathing

These signs may appear suddenly, sometimes with no warning. In severe cases, the person may lose consciousness or go into shock, a life-threatening condition. "Warning symptoms include dizziness, confusion, blurred vision, fainting, and cold or sweaty skin," says Dr. Sibia. "Some may ignore these symptoms, assuming they are insignificant, but ignoring them can delay treatment and worsen outcomes."

"Acute hypotension is a sudden and severe drop in blood pressure that can be deadly if not treated right away," says Dr. Rahul Mehrotra, Chief - NIC & Clinical Cardiology, Artemis Hospitals. "When BP gets too low, these organs don't get enough blood, which can lead to organ failure and even death." Dr. Mehrotra highlights the top medical emergencies that often result in sudden hypotension:

• Major bleeding (from trauma or internal injuries)
• Heart attack
• Sepsis, a life-threatening infection
• Anaphylaxis, a severe allergic reaction
• Severe dehydration

He further emphasizes that not all cases of low BP are dangerous. "When blood pressure is low but not too low, it usually isn't a big deal for healthy people. But a sudden and severe drop in blood pressure should never be ignored."

How Fast Can A Drop In Blood Pressure Turn Fatal?

The progression from a sudden drop in blood pressure to life-threatening complications can be rapid. When blood flow to vital organs is interrupted, shock can develop within minutes, leading to organ failure and, if untreated, death.

Dr. Yogendra explains, "Sometime a sudden drop in the blood pressure may be because of sudden loss of fluid inside the body like severe dehydration due to loose motions, due to excessive vomiting, due to excessive blood loss, due to internal organ injury or due to internal blood loss in the form of rupture of gastric ulcer. So there are many things which can cause drop in the blood pressure and ultimately patient may succumb to death."

When Is a Low Blood Pressure considered an Emergency?

While some people live with chronically low blood pressure without symptoms, a sudden and significant drop—especially with symptoms—should always be treated as a medical emergency. Dr. Mehrotra emphasizes, "You should never ignore a sudden and severe drop in blood pressure. IV fluids, medications, and emergency procedures are all examples of timely medical care that can save lives. In short, a sudden drop in blood pressure can be deadly if you don't get help. Being able to see the warning signs early can make a big difference."

While a slight drop in blood pressure can occur from something as benign as standing up too fast, a sudden and unexplained dip should not be taken lightly. Acute hypotension is not just about numbers on a monitor — it’s about how the body responds when critical systems are deprived of oxygen-rich blood.

As Dr. Rajput puts it bluntly, "Yes, a sudden drop in blood pressure can cause sudden death." While mild, brief episodes may cause only dizziness, a rapid and significant decline can be life-threatening, especially if it signals a heart attack, severe bleeding, sepsis, or anaphylaxis. Recognizing the symptoms and seeking immediate medical help can be the difference between recovery and tragedy.

Disclaimer: If you or someone around you experiences sudden and unexplained symptoms of low blood pressure, treat it as a true emergency. Always consult a qualified healthcare professional for diagnosis, treatment, or concerns about your health.

The shape of your gluteus maximus, the largest muscle in your backside, may offer surprising clues about your likelihood of developing diabetes. New research suggests that the contours of this major muscle change with age and health conditions, helping scientists better understand how fitness, muscle health, and metabolism are connected.

Ageing, Weight, and Diabetes: What We Already Know

For years, the NHS has warned that ageing and excess weight increase the risk of developing Type 2 diabetes. However, this new study goes beyond traditional measures, proposing that the shape of the gluteus maximus itself shifts as people age or develop conditions such as osteoporosis or diabetes. These subtle muscular changes could provide valuable information about a person’s metabolic health.

Why the Gluteus Maximus Matters

Researchers from the University of Westminster highlighted that the gluteus maximus plays a key role not just in movement but also in metabolic regulation. Healthy, well-maintained muscles can improve blood sugar control and reduce the burden on organs involved in glucose processing.

Dr Marjola Thanaj, co-author of the study from the university’s Research Centre for Optimal Health, explained, as reported by Independent: “People with higher fitness, as measured by vigorous physical activity and hand grip strength, had a greater gluteus maximus shape, while ageing, frailty and long sitting times were linked to muscle thinning.”

Mapping the Muscle

To understand these differences, researchers used advanced MRI 3D mapping to create a detailed anatomical model of the gluteus maximus. By analyzing more than 61,000 MRI scans from the UK Biobank database, they discovered that the shape, not the size, of the muscle varied significantly between individuals with diabetes and those without it.

What the Study Found

The MRI analysis revealed distinct, sex-specific patterns linked to Type 2 diabetes. Among male participants living with the disease, those classified as “frail” showed widespread muscle shrinkage across the gluteus maximus, indicating a loss of muscle quality and strength.

Women with diabetes, on the other hand, had enlarged muscle shapes — not because of increased muscle strength, but because of fat infiltrating the muscle tissue. This type of fat infiltration often signals declining muscle function and poorer metabolic health.

Dr Thanaj said these patterns underline a crucial point: men and women can experience the same illness in very different biological ways, which may influence diagnosis and treatment strategies in the future.

Why Maintaining Muscle Mass Matters

Beyond appearance or strength, muscle health is essential for long-term wellbeing. Maintaining muscle mass supports blood sugar regulation, reduces the risk of cardiovascular disease, and lowers the likelihood of developing fatty liver disease, all conditions closely linked to metabolic health.

Professor Louise Thomas, senior author of the study, told The Times: “Maintaining muscle mass as we age is one of the most important things we can do for our long-term health. If people understand how important their muscles are, and make small changes to keep them healthy, that could have a huge impact on disease across the population.”

Small Steps to Strengthen Your Glutes

Improving glute muscle health doesn’t require intense gym sessions. Simple actions such as taking the stairs instead of the lift, adding squats or lunges to your routine, or breaking up long periods of sitting can help tone and strengthen the gluteus maximus.

Kidney disease is rising at an alarming pace worldwide, and it’s now among the top causes of death. A Lancet study highlights that the number of people living with chronic kidney disease jumped from 78 million in 1990 to nearly 788 million in 2023. That’s a massive tenfold spike, and a reminder that our kidneys need more attention than we realize.

The tricky part? Kidney problems often progress silently. Many people don’t realize anything is wrong until the kidneys are already significantly damaged. That’s why experts strongly emphasize early screening. According to nephrologists like Dr Arjun Sabharwal, a few simple tests — often quick and inexpensive — can help catch kidney issues early and improve treatment outcomes.

Below are the four key tests everyone should know about, especially if you have diabetes, high blood pressure, a family history of kidney disease, or you’re simply trying to stay proactive about your health.

Creatinine Blood Test & eGFR: Your First Kidney Health Check

eGFR uses creatinine values along with age and other factors to estimate how well your kidneys are functioning overall. Doctors often say, “Creatinine is just a number — eGFR tells you how much your kidneys are working.”

An eGFR below normal may be an early signal that your kidneys aren’t filtering efficiently, even if you feel fine.

Cystatin C: A More Accurate Indicator for Some People

Cystatin C is a protein produced naturally by all cells. When kidneys are healthy, its levels stay stable; when the kidneys struggle, the levels rise.

Experts highlight that Cystatin C can be more reliable than creatinine for people with very high muscle mass, those who work out intensely, or individuals taking supplements that may affect creatinine readings. If creatinine results seem unclear or inconsistent, this test adds clarity.

Urine Dipstick Test: Quick and Tells You a Lot

Before kidney function takes a major hit, the body often shows early warnings — one of which is protein leakage in urine. A urine dipstick test is one of the fastest ways to detect this.

A chemically treated strip is dipped into your urine sample, and if proteins like albumin are present, the strip changes color. It’s simple, non-invasive, and helpful for spotting early kidney damage.

Urine Protein-to-Creatinine Ratio (UPCR): How Much Protein Is Leaking

If a dipstick shows abnormalities, the next step is often a UPCR test. This test measures exactly how much protein is leaking into the urine relative to creatinine. Higher levels may signal worsening kidney function or underlying disease. Doctors use UPCR to assess the severity of kidney damage and monitor progress over time.

When to See a Nephrologist

If any test shows rising creatinine, an abnormal eGFR, protein in urine, or blood detected on a dipstick, it’s crucial to book an appointment. Lifestyle tweaks, home remedies, or detox drinks cannot reverse kidney damage. Expert evaluation is essential.

In 2025, thanks to climate change, rapid urbanization, and frequent travels, new viruses, their strains, and infections have spread frequently. Infections have affect millions and some diseases have come back with their new strains, which have been more contagious, whereas other diseases are finding new ways to emerge.

As we look back at the year, which is about to end in just another month, let us look back at the top 5 infectious diseases of 2025.

Respiratory Infections

In 2025, respiratory infections were the most widespread, with new COVID-19 variants emerging every now and then. Along with this common flu too has emerged. This has weakened immunity and made elderly and infants, and people with comorbidities more vulnerable to the diseases.

The new COVID variants in India are linked with the JN.1 variant and its sub-variants like LF.7 and NB.1.8. The COVID variants in the UK which were active were XFG, NB.1.8.1, or known as the Stratus and Nimbus variants. Other variants were XFG.3, XFG.5, and XFG.3.4.1.

Tuberculosis (TB)

Tuberculosis still continues to be a major infectious disease in 2025, especially in countries like India. As per the World Health Organization (WHO), tuberculosis caused 1.25 billion deaths in 2023. It becomes the world's leading infectious disease after COVID-19.

Each day, close to 3,425 people lose their lives to TB, and close to 30,000 people fall ill with this preventable and curable disease. About 10.8 million people got TB in 2023, which include 6 million, 3.6 million women, and 1.3 million children.

Dengue and other mosquito-borne infections

Mosquito-borne diseases like dengue, chikungunya, malaria, and Zika continued to rise in 2025. The reason being changing weather patterns. Dr Sanjeev Bagai, Chairman of Nephron Clinic, and Senior Consultant Pediatrician and Nephrologist points out that earlier the mosquito-borne diseases were seasonal, however, due to rapid urbanization and climate changes, these diseases have stayed all round the year.

Hepatitis Infections

Hepatitis B and Hepatitis C are among the most common Hepatitis infections in 2025. However, there have been outbreaks of Hepatitis A and E in unsafe water and food. Chronic hepatitis can also damage liver and also lead to cancer. It is a concern because it spreads through contaminated food, unsafe water, blood, and sexual contact. While many people may not show symptoms until serious liver damage occurs.

Symptoms also include jaundice, dark urine, fatigue, nausea, and abdominal pain.

Gastrointestinal Infections

Food- and water-borne infections are still common across the world. Illnesses like salmonella, cholera, rotavirus, and norovirus often spread in areas where hygiene, sanitation, and food safety are poorly maintained.

Why are these infections risky?

They can spread extremely fast, especially among children and older adults. Severe diarrhea and vomiting can lead to dangerous dehydration if not treated in time.

What symptoms should you look out for?

Persistent diarrhea, vomiting, stomach cramps, fever, and signs of dehydration. The best prevention is simple: drink clean water, wash hands regularly, and eat properly cooked food.