Explained: Can Stomach Cancer Spread To Other Organs?

Updated Nov 26, 2024 | 04:25 PM IST

SummaryStomach cancer develops in the lining of the stomach. However, this form of cancer can spread through other parts of the body through three main pathways: direct spread, lymphatic spread, and bloodstream.
Stomach Cancer

Stomach Cancer (Credit: Canva)

Stomach cancer develops in the lining of the stomach. Also, known as Gastric cancer, it affects the elderly more than the adult. According to the American Cancer Society, about 6 of every 10 people diagnosed with stomach cancer each year are 65 or older. Also, the lifetime risk of developing stomach cancer is higher in men (about 1 in 101) than in women (about 1 in 155).

Oncologist Dr Pankaj Kumar Pande, Director–Surgical Oncology, Max Super Speciality Hospital, Shalimar Bagh, Delhi explained that this form of cancer spreads through three main pathways: Direct spread, lymphatic spread, and bloodstream.

1. Direct Spread: In its early stages, stomach cancer can invade nearby tissues and grow into the deeper layers of the stomach or spread to surrounding organs such as the oesophagus, liver, pancreas, or intestines.

2. Lymphatic Spread: Cancer cells can travel through the lymphatic system. The most common areas affected are the regional lymph nodes near the stomach, particularly those around the liver and diaphragm.

3. Bloodstream: "Cancer cells can enter the bloodstream and travel to distant parts of the body," which is a common route for stomach cancer to metastasize to distant organs.

He further explained that cancerous cells spread from the original tumour to other parts of the body through a process called Metastasis. The most common sites for the spread are the liver, lymph nodes, peritoneum, lungs, bones, and ovaries.

What Are the Early Warning Signs of Stomach Cancer?

The early warning signs of stomach cancer are often subtle and can be easily overlooked. Some of the common early signs include:

- Indigestion or Discomfort: Mild indigestion, bloating, or a feeling of fullness after eating can often be dismissed as normal but may indicate an early stage of stomach cancer.

- Loss of Appetite: A lack of interest in food or feeling full quickly, which can be intermittently noticed and often attributed to stress or other non-cancer causes.

- Unexplained Weight Loss: Losing weight without trying or experiencing an unexplained drop in appetite, which may signal cancer progression.

- Abdominal Pain or Discomfort: Persistent or occasional pain in the stomach area, often after eating, can become more severe as the condition progresses.

- Nausea or Vomiting: Nausea, sometimes accompanied by vomiting, may occur especially after meals and is linked to cancer blocking or irritating the stomach.

- Heartburn or Acid Reflux: Persistent heartburn that doesn't respond to usual treatments could signal stomach cancer.

Dr Pande notes that "In the early stages, these symptoms tend to be mild and intermittent," leading many to attribute them to less serious digestive issues. Unfortunately, this often results in the cancer being diagnosed at a more advanced stage.

Recommended Lifestyle Changes After Cancer Treatment

After undergoing treatment for stomach cancer, adopting lifestyle and dietary changes can significantly improve recovery and reduce the risk of recurrence. Dr Pande advises patients to focus on a balanced diet, consisting of fruits, vegetables, whole grains, lean proteins, and fiber-rich foods, to aid digestion and overall health. "Eat small, frequent meals and stay hydrated with fluids like water or herbal teas," he recommends.

As far a lifestyle alterations are concerned, he emphasizes the importance of regular physical activity, starting with light exercises to rebuild strength. He also suggests managing stress through relaxation techniques and prioritizing adequate sleep (7-9 hours a night) for effective healing. Additionally, regular check-ups and screenings are vital for ongoing monitoring.

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Prone To Developing Cold Sores? You May Be Risk For This Cognitive Disease

Updated May 22, 2025 | 12:09 PM IST

SummaryCold sores are difficult and uncomfortable to deal with. However, can they be a sign of something going worse with your health?

(Credit-Canva)

Cognitive decline is one of the most common diseases that people experience with age. Dementia is an umbrella term used to define symptoms of decline in brain function, whether it is memory, thinking skills or other mental abilities. While the risk factors, causes and treatment options are known, researchers explain that they are still being studied, and every new study brings an interesting perspective about the disease. As there is no proper cure for the disease, people have to rely on medication that slows the disease down.

A new study may have found not just a risk factor for Alzheimer’s disease but also a way to lower the potential of developing the cognitive decline.

Risk Factors for the Disease

A new study done by researchers from pharmaceutical firm Gilead Sciences and the University of Washington in Seattle, suggested that people who get cold sores might be nearly twice as likely to develop Alzheimer's disease. US researchers discovered that individuals carrying the herpes simplex virus type 1 (HSV-1), which causes cold sores, had an 80% higher chance of developing this brain-wasting condition.

Other risk factors include age, family history, genetics, certain medication or injuries. Whie most of these are irrefutable things, research has shown that that can be tackled with things like learning a new skill, exercising daily, quitting smoking, eating healthy as well as maintaining a healthy weight.

What Are Cold Sores And Causes

Cold sores are small blisters around one’s mouth, also known as fever blisters. They are caused by a virus known as herpes simplex, and the most common strain of it is herpes simplex virus 1. This is a communicable infection that can spread through kissing or sharing utensils or even towels.

John Hopkins Medicine explained that if the virus transfers to you, it will cause a breakout of cold sores. These sores can be triggered by sunlight, cold wind or other illnesses that can weaken your immune system like hormone levels and even stress.

Antiviral Treatment Shows Promise

However, the study also offered a ray of hope: those who received antiviral medicines for HSV-1 had a 17% lower risk of Alzheimer's compared to those who didn't. This finding is significant because the virus has been linked to changes in the brain similar to those seen in dementia patients, such as plaque-like formations and inflammation.

The study, a collaboration between pharmaceutical firm Gilead Sciences and the University of Washington in Seattle, analyzed data from over 344,000 individuals with Alzheimer's and an equal number without the disease. It found that 1,507 (0.44%) of Alzheimer's patients had a history of HSV-1 diagnosis, compared to just 823 (0.24%) of those without the disease. These findings were published in the journal BMJ Open.

Things To Keep In Mind

Experts emphasized that HSV-1 infection, which is very common, does not guarantee someone will develop Alzheimer's. The exact reason why viral infections might increase dementia risk isn't fully understood, but it's likely due to infections causing more inflammation in the body, contributing to age-related brain inflammation.

They also explained that there isn't enough evidence yet to add infections to the list of 14 established risk factors for dementia. The researchers pointed out that the research relied solely on health records, meaning some HSV-1 infections might not have been recorded since many people don't show symptoms. Additionally, information about infections predating the records wasn't available, and diagnosing Alzheimer's, especially early on, remains a challenge.

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Sudden Cardiac Arrests Could Be Linked To Bodybuilding: Study

Updated May 22, 2025 | 11:00 AM IST

SummaryBodybuilders may spend hours perfecting their physique, mastering fitness and controlling their diets, but that may not be enough to protect their health.
Sudden Cardiac Arrests Could Be Linked To Bodybuilding: Study

(Credit-Canva)

One of the most grueling and difficult fitness regime people go through is bodybuilding. The regime was made to enhance the muscles of the human body. As a sport, it is bodybuilders who train their muscles to artistically display the pronounced muscle mass, symmetry as well as overall aesthetics. Building muscles mass includes doing exercises like strength training, resistance training devices as well as cardio. These exercises help bodybuilders keep their body fat at the lowest possible.

Being the epitome of health, many people believe that body builders live healthy and long lives. However, a new study shed light on the concerning link between bodybuilding and sudden deaths.

Major Health Risks Related To Bodybuilding

Bodybuilders may spend endless hours building impressive muscles, but a new study shows their hard work might harm their hearts. Research in the European Heart Journal found that many male bodybuilders die suddenly from heart issues. What's more, professional bodybuilders are five times more likely to have a sudden heart attack than amateurs.

Researchers highlighted that the risk of death for male bodybuilders is notably high. They noted that competing at a professional level seems to increase this risk, with pros having many more sudden heart deaths. This study started because of more and more reports of early deaths and heart attacks in the bodybuilding world.

The study also found that about 15% of bodybuilder deaths were classified as "sudden traumatic deaths," which include car accidents, suicides, murders, and overdoses. Experts stressed that these findings show we need to think about the mental impact of bodybuilding culture, noting that mental health issues can sometimes get worse with drug abuse, leading to risky or self-harming behaviors.

Study Methodology and Findings

Researchers looked at information from 20,300 athletes who competed in International Federation of Bodybuilding and Fitness (IFBB) events between 2005 and 2020. The IFBB is the main group for bodybuilding contests worldwide. The study followed these athletes' health until July 2023, for over eight years on average. During this time, 121 bodybuilders passed away.

A shocking 38% of these deaths were due to sudden cardiac death, meaning their hearts just stopped. Sadly, 11 of these cases happened to active competitors who were, on average, just under 35 years old. Experts pointed out that sudden heart death can happen even to young, seemingly healthy people without known heart problems, though it's rare.

What Increases The Risk?

Experts pointed to several practices common in bodybuilding that can strain the cardiovascular system:

Extreme strength training: Intense physical exertion can put immense pressure on the heart.

Rapid weight loss strategies: Severe dietary restrictions and dehydration can disrupt the body's delicate balance.

Widespread use of performance-enhancing substances: These can have detrimental effects on heart health.

How Does It Affect Your Heart?

These things can cause irregular heartbeats and changes to the heart's structure over time. Autopsies of five bodybuilders in the study showed that four had enlarged hearts and thicker heart muscles, which make heart failure more likely.

Professionals face a higher risk because they often push these practices harder for longer periods and feel more pressure to get extreme physiques. Experts warned bodybuilders, that aiming for physical perfection is great, but trying for extreme body changes at any cost can be very risky their health and heart.

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Your Chronic Health Struggles Could Be Doubling Your Risk Of Depression- Here’s What To Know

Updated May 22, 2025 | 03:00 AM IST

SummaryPeople with multiple chronic illnesses face a 2.4 times higher risk of depression, especially those with migraines, lung issues, or digestive conditions—highlighting the urgent need for integrated physical and mental healthcare.
Your Chronic Health Struggles Could Be Doubling Your Risk Of Depression—Here’s What to Know

Credits: Canva

Living with a chronic illness can be like fighting an uphill battle—physically, mentally, and emotionally. But new research indicates the cost may be even deeper than most people know: long-term physical illness may dramatically raise your risk of developing depression.

As a revolutionary study in Nature Communications Medicine explains, individuals with many chronic conditions are much more likely to experience a mental health breakdown. This finding explains the essential, but frequently overlooked, connection between body and mind.

Traditionally, healthcare systems everywhere have addressed physical and mental illness as separate silos. But new science is presenting a different picture—one where body and mind are highly intertwined.

In the recent U.K. Biobank study, researchers followed over 142,000 adults aged between 37 and 73, all of whom had at least one chronic illness but no prior diagnosis of depression. The findings were eye-opening: individuals with multiple physical conditions were up to 2.4 times more likely to be diagnosed with depression over the next decade compared to those without chronic illnesses.

The report's co-author, Professor Bruce Guthrie from the University of Edinburgh, underscored the significance: "Healthcare tends to think of physical and mental ill health as two totally separate things, but this research indicates that we must do better at predicting and treating depression in individuals who have physical illness."

Which Conditions Have the Highest Risk?

While any long-term illness will erode mental toughness, some combinations greatly increase depression risk. Among the study's most surprising findings:

Individuals with migraine illness or chronic respiratory disease had twice the risk of depression.

A combination of heart disease and diabetes raised depression risk by almost 78%.

Gastrointestinal illnesses such as IBS, celiac disease, and liver disease were associated with an 83% increased risk of depression in women and a twofold increase in risk in men.

These figures are more than just statistics—they represent real individuals facing a double burden of illness and emotional distress. And with 1 in 12 people in high-risk groups developing depression over a decade (compared to 1 in 25 among those without chronic conditions), the data calls for urgent attention.

Why Is Depression Always More Than Just Feeling Sad?

In order to comprehend why this is important, it's necessary to know what depression actually is. Clinical depression, also known as major depressive disorder, is a mood disorder that extends far beyond fleeting sadness. It's a complex illness that influences the way individuals think, feel, and behave. Symptoms can involve:

  • Constantly feeling sad or hopeless
  • Loss of interest in activities once enjoyed
  • Fatigue or loss of energy
  • Trouble concentrating or making decisions
  • Changes in appetite or sleep habits
  • Physical symptoms like sudden pain
  • Integers of suicide or harming oneself

Depression is not a personal failing or something you can simply "snap out of." It is a genuine medical illness that more often than not needs to be treated by professionals—such as therapy, medication, or both.

Biological and Emotional Roots of Depression in Chronic Illness

Why chronic illness would so greatly increase the risk of depression? Experts consider the causes to be multifactorial.

Physiologically, certain chronic diseases interfere with brain chemistry or hormonal equilibrium, both of which play a critical role in regulating mood. Such conditions as thyroid disease or diabetes, for example, can have a direct effect on neurotransmitters associated with depression.

Emotionally, the ongoing juggling act of pain, tiredness, and doctor visits can be draining. Throw in social isolation, financial burden, or loss of autonomy, and it is not hard to understand how emotional well-being can start to fray.

When to Seek Help?

If you or someone close to you is living with a chronic illness, it is important to remain aware of depression symptoms. Early treatment makes a real difference in the outcome of care and the quality of life.

Do not wait until things get worse. If you see signs such as lingering unhappiness, loss of initiative, or constant exhaustion, seek professional attention. A visit to a primary care doctor or mental health expert can be an important first step.

This new research supports what many patients have long intuited—real wellness can't be realized without attending to body and mind. It's high time for medical providers, policymakers, and insurers to adopt a more integrated strategy for the management of chronic disease that encompasses preventive screening and treatment for mental illness.

Lead researcher Lauren DeLong said it best: "We noticed obvious links between physical health conditions and the occurrence of depression, but this research is just the start. We hope our research will encourage other scientists to explore and disentangle the connections between physical and mental health conditions."

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