Hand Conditions That May Be Symptoms Of Underlying Disease

Updated Jan 6, 2025 | 09:00 PM IST

SummaryThe form, function, and appearance of hands can offer important prognostic and diagnostic clues. Here are some of the diseases which can be gauged by your hands.
Hands

Hands (Credit: Canva)

Your hands reflect a lot of things, including your health conditions. While things like finger trembling and swelling (in winters) are common, sometimes they can get serious. Notably, the form, function, and appearance of hands can offer important prognostic and diagnostic clues. Here are some of the diseases which can be gauged by your hands:

1. Red Hands

Redness in the hands or palms is caused by dilated capillaries and may be influenced by hormone changes in the body, which typically occur during pregnancy. Thus, red hands are common in pregnant women. Red hands, also called palmar erythema, Lane's disease, liver palms, or red palms, can also be hereditary.

2. Hand Rash

A red rash on your hand or wrist might indicate a nickel allergy, sometimes morphing into oozing blisters. Sensitivity to nickel is one of the most common causes of allergic contact dermatitis. Many everyday objects touching your skin—such as bracelets, watches, rings, and cell phones—contain nickel. You can also develop a hand rash from ingesting foods containing nickel, such as buckwheat, cashews, cocoa powder, licorice, and soy products.

Atopic dermatitis, a chronic skin condition, can also appear as a rash on the hands, causing inflammation, redness, irritation, and severe itching.

3. Finger Clubbing

Finger clubbing is a change to the nailbeds that may indicate underlying health conditions. Symptoms include large, bulging fingertips that may be red and warm to the touch, rounded nailbeds, a sharpened angle between the nailbed and cuticle, and softened nailbeds. This condition is often linked to heart and lung diseases like lung cancer, endocarditis, and congenital heart defects.

4. Hand Pain, Stiffness, and Swelling

Pain, stiffness, and swelling in your hands can occur if you have inflammatory diseases such as rheumatoid arthritis, psoriatic arthritis, or inflammatory bowel disease.

5. Hand Tremors

A little hand shakiness is common, especially if you are sleep-deprived, over-caffeinated, or experiencing alcohol withdrawal. However, persistent tremors can be a sign of neurological diseases like Parkinson's. Essential tremor, which often runs in families, causes hand and arm shakiness during tasks like eating.

6. Numb or Tingly Hands

Pins and needles in your hands could indicate carpal tunnel syndrome, especially if you experience weakness, shock-like sensations, or nighttime numbness. This condition is caused by compression of the median nerve.

7. Purple Finger Nodules

Painful red or purple bumps on your fingertips, known as Osler nodes, may signal endocarditis, a serious but rare disease causing heart inflammation.

8. Psoriasis

This chronic autoimmune condition causes thick, red patches of skin and silvery scales, often affecting the hands and nails. Palmoplantar psoriasis can lead to painful cracking, fissuring, and nail changes.

9. Trigger Finger

Trigger finger, or stenosing tenosynovitis, causes a finger to pop, catch, or get stuck when bending. This condition is often seen in people with diabetes, rheumatoid arthritis, or thyroid disease.

10. Weak Handgrip

Weak hand strength can result from aging but may also indicate poor overall health. Research links stronger handgrip strength to better heart health.

11. White, Blue, or Red Fingers

Color changes in your fingers might indicate Raynaud's phenomenon, a condition caused by reduced blood flow during cold or stress. It can cause numbness, pain, and tingling in the fingers.

End of Article

Bacterial Meningitis May Cause Long-term Fatigue, Vision Problems, Raise Suicide Risk: Study

Updated Mar 24, 2026 | 03:00 AM IST

SummaryThe long-term effects of the deadly bacterial meningitis among survivors include fatigue, difficulties with concentration, memory and emotional regulation, persistent headaches, issues with mobility, vision, and hearing.
Bacterial Meningitis May Cause Long-term Fatigue, Vision Problems, Raise Suicide Risk: Study

Credit: Canva

From physical problems like fatigue and vision problems, people who survive the deadly bacterial meningitis are likely to live with long-term fatigue and vision problems, as well as be at high risk of suicide, according to a new study.

The study comes as the UK is experiencing an outbreak of meningitis in Kent, that began among students who visited Club Chemistry in Canterbury between March 5 and 7.

Although bacterial meningitis is treatable, it requires prompt, often immediate treatment for better recovery. Yet patients are likely to face the risk of fatal or long-term complications -- from physical, psychological, and social impacts, said researchers from the University of Otago, The Conversation reported.

The new findings, based on 16 cases from New Zealand, who reportedly suffered the fatal disease, showed that multiple chronic after-effects is permanent in some, while in others, it dragged on for years. The effects include:

  • fatigue,
  • difficulties with concentration,
  • memory and emotional regulation,
  • persistent headaches,
  • issues with mobility, vision, and hearing.
These conditions affected the patients' ability to work, study, and maintain relationships, which further affected their mental health, increasing their vulnerability for

  • anxiety,
  • depression
  • suicidality.

"Our findings demonstrate that bacterial meningitis is much more than a life-threatening infection. It is an acute disease with serious, chronic after-effects which are poorly understood and often go unrecognised," the researchers said.

Kent Meningitis Outbreak

According to the latest update from the UK Health Security Agency (HSA), 20 laboratory cases of meningitis are confirmed, and 9 notifications remain under investigation, bringing the total to 29 in the country.

The bug that causes the infection has been identified as the known strain of meningitis B, and MenB vaccines will be offered to 5,000 students living in the University of Kent halls of residence in Canterbury.

Meanwhile, the UKHSA chief executive, Susan Hopkins, said the outbreak "looks like a super-spreader" event with "ongoing spread" through universities' halls of residence.

"There will have been some parties, particularly around this, so there will have been lots of social mixing. I can't yet say where the initial infection came from, how it's got into this cohort, and why it's created such an explosive amount of infections," she added.

As per Trish Mannes, UKHSA Regional Deputy Director for the South East, even after two doses, the MenB vaccine “does not protect against all strains of meningococcal disease, nor against all infections that can cause meningitis. It also does not prevent the bacteria from being carried and spread in the community”.

The UKHSA thus warned people to be aware of the signs and symptoms of invasive meningococcal disease, and to seek immediate medical attention if they or anyone they know develops these signs and symptoms.

Common symptoms include:

  • rash
  • sudden onset of high fever
  • severe and worsening headache
  • vomiting and diarrhea
  • joint and muscle pain
  • seizures.

End of Article

Study claims being tall can make you more prone to heart disease, endometriosis

Updated Mar 24, 2026 | 02:00 AM IST

Summary​The genetic variants responsible for tall stature increased the risks of both atrial fibrillation and endometriosis. In comparison, the genetic factors for short statures offered a slight protection against endometriosis.
Study claims being tall can make you more prone to heart disease, endometriosis

Credit: iStock

Being tall can have its advantages, but a new genetic study linked height with significant health problems, such as a higher risk of developing heart disease and endometriosis throughout one's lifetime.

While genetics and environmental factors together influence a person’s height, the stature can also prove to be a risk factor for determining the risk of atrial fibrillation, which occurs when the heart quivers rapidly and erratically instead of beating regularly, said the researchers from the China Medical University Hospital in Taiwan.

“By integrating genetic data across multiple East Asian biobanks, we show that the genetics of stature is linked not only to growth-related traits but also to clinically relevant outcomes—most notably atrial fibrillation and endometriosis," said the team in the paper.

"These results suggest that stature-related polygenic scores could help improve early risk stratification in East Asian populations,” they added.

Also read: Woman Left Medically Infertile After Seven Surgeries For Endometriosis That She Did Not Have

Key Findings

The team led by Fuu-Jen Tsai conducted a large-scale genetic analysis on people of East Asian origin. They analyzed 120,000 Han Taiwanese individuals and compared them with 27,966 controls with familial short stature (FSS) -- a harmless condition where people are short due to inherited genetics -- to find genetic factors.

The study also linked a person’s height to overall body size and lung function, as well as cardiovascular traits and reproductive traits, including the age when menstruation starts.

Their findings, published in the journal PLOS Genetics, identified 293 genetic variants linked to height and five linked to familial short stature.

The genetic variants responsible for tall stature increased the risks of both atrial fibrillation and endometriosis. In comparison, the genetic factors for short statures offered a slight protection against endometriosis.

The results proved that taller stature increased the risk of atrial fibrillation independently. But the risk of endometriosis was determined through menarche/weight in taller people.

The Role Of Estrogen

A 2020 study from Denmark shares a possible explanation for the link between height and increased risk of atrial fibrillation: the rising estrogen levels.

Estrogen is a hormone known to promote the growth of the lining of the womb and is also believed to play a role in growth spurts during puberty.

The study, published in the Annals of Human Biology, showed that taller and slim girls in childhood had a high risk of developing endometriosis. The study also marked a lower body mass index as an increased risk of endometriosis.

However, further research is needed to validate these associations and inform clinical applications.

End of Article

US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

Updated Mar 24, 2026 | 12:00 AM IST

SummaryOne person might have very high cholesterol for 30–40 years, while another has moderately elevated levels for 60 years. Over time, their total exposure can be similar—and so can their risk, said Dr. Nils P Johnson, Professor of Cardiology, University of Texas, US.
US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

Credit: iStock

Early monitoring among younger populations has been the primary focus of the recently released American Heart Association (AHA) 2026 cholesterol guidelines.

The deliberate shift is reportedly based on new evidence about how heart disease develops over time.

Speaking exclusively to HealthandMe, Dr. Nils P Johnson, Professor of Cardiology, University of Texas, Houston, US, shared that atherosclerosis, or the buildup of plaque in arteries, doesn’t suddenly appear in middle age; it begins silently in youth.

That is why the AHA guidelines highlighted the importance of early screening.

“Cholesterol risk is really about long-term exposure. Just like years of breathing polluted air can damage your lungs, cholesterol builds up in the body over time. It’s not just about how high your levels are at one moment—it’s about how long you’ve lived with them. For example, one person might have very high cholesterol for 30–40 years, while another has moderately elevated levels for 60 years. Over time, their total exposure can be similar—and so can their risk," Dr. Johnson said.

What this means in practice is that treating cholesterol is about reducing total lifetime exposure.

The cardiologist explained that there are two ways to do that: lower cholesterol levels or start treatment earlier.

"Both approaches achieve the same goal—shrinking the overall ‘cholesterol burden’ by reducing how much cholesterol is in the body and how long a person is exposed to it,” the expert said.

The AHA 2026 Cholesterol Guidelines

As per the Global Burden of Disease Study 2021, the burden of heart failure in adolescents and young adults aged 10–24 years is increasing globally.

The guidelines call for early intervention through early screening and healthy lifestyle changes, starting from childhood.

It recommends:

  • Children (9-11 years): Cholesterol screening if never done before.
  • Adults (30-79 years): Evaluate 10- and 30-year ASCVD risk to determine the need for early intervention
  • Considering lipid-lowering therapy for young adults with -- persistent LDL of at least 160 mg/dL, strong family history of ASCVD, and/or at least 10 percent 30-year risk for ASCVD

"They encourage us to think beyond the usual 5- or 10-year risk window and consider the long-term picture—what might happen 20 or 30 years down the road for someone in their 40s or 50s,” Dr. Johnson told HealthandMe.

Also read: ACC/AHA Cholesterol Guidelines 2026 Explained: Start Screening For Cardiovascular Diseases Early

Heart Disease: A Long-term Treatment

The heart expert also stated that chronic conditions like heart disease require long-term management—sometimes for decades—unlike an infection, where a two-week antibiotic course resolves the problem.

“One of the biggest challenges I see in clinics is that patients often come in after a dramatic event—chest pain, a heart attack, or a procedure. Alongside immediate treatment, I prescribe medications and recommend lifestyle changes. And then patients ask, ‘How long do I have to do this? This reflects a very different mindset”.

Dr. Johnson urged cardiologists and other healthcare workers to help patients understand, accept, and sustain these changes over the long term.

“Adjusting to the reality that life will be different for years or even a lifetime is not easy, but it’s essential,” he said.

End of Article