Huntington’s disease (HD) is a condition that is hereditary and causes nerve cells in specific parts of the brain to slowly deteriorate and die. The disorder affects regions responsible for controlled and intentional movements, as well as those tied to mood, thinking, and personality. People with HD often develop jerky, dance-like body movements known as chorea, along with unusual postures and emotional or cognitive changes. For instance, they may experience sudden, uncontrollable motions in their hands, feet, face, or torso. These movements tend to worsen when the person feels anxious or distracted, and as the disease advances, they become more frequent and harder to manage.

Is Huntington’s Disease Genetic?

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The institute further explains that children who do not receive the mutated gene will never develop HD and cannot pass it on to their own children.

What Causes Huntington’s Disease?

Over time, this unstable protein builds up in the brain and damages nerve cells. As the mutation is inherited in an autosomal dominant pattern, one copy of the defective gene is enough to cause the disorder.

Huntington’s Disease Can Now Be Treated With Gene Therapy

The results, shared by the Amsterdam-based gene therapy company uniQure, were considered statistically significant across several clinical measures. Researchers also found lower levels of a harmful protein linked to brain cell damage in the spinal fluid of participants who received the treatment. Encouraged by these results, uniQure has announced plans to seek regulatory approval next year.

“This gene therapy represents a major step forward,” said Dr. Sandra Kostyk, a neurologist at Ohio State University Wexner Medical Center and one of the study’s investigators. “The data are encouraging.”

She added that while slowing the illness could mean more years of independence for patients, it is not a cure. Because of the small number of participants, more research and long-term follow-up are still needed.

Huntington’s Disease Symptoms You Need to Be Aware OfPeople with Huntington’s disease often lose control over their voluntary movements, which can affect daily functioning more severely than the involuntary jerks caused by chorea. Difficulties with voluntary movement can make it harder to work, communicate, and maintain independence.

According to the National Health Service, early signs may include trouble focusing or organizing tasks, forgetfulness, irritability, impulsive behavior, and changes in mood such as depression or anxiety. Other symptoms include small, uncontrollable jerks or twitches, clumsiness, and problems managing muscles.

Interestingly, symptoms can appear at any age but most often begin in a person’s 30s or 40s. When it develops before the age of 20, it is called juvenile Huntington’s disease. In such early-onset cases, symptoms may differ and the illness usually progresses more rapidly.

Cancer deaths in the United Kingdom have dropped to their lowest recorded levels, according to new data from the charity Cancer Research UK. The figures show that cancer death rates have fallen by 11 per cent in the past decade, reflecting progress in early detection, screening, treatment and prevention.

Researchers estimate that around 247 people in every 100,000 in the UK now die from cancer each year. This is a significant decline from the peak recorded in 1989, when about 355 people per 100,000 died annually from the disease. Overall, that represents a 29 per cent reduction over the past few decades.

Experts say this steady improvement is the result of sustained scientific progress, improved healthcare systems and public health measures that target risk factors such as smoking.

Major Declines In Several Common Cancers

The new data highlights falling death rates across several major cancers. Ovarian cancer deaths have dropped by 19 per cent over the past ten years, up to 2024. Lung cancer deaths have fallen by 22 per cent during the same period, reflecting the long-term impact of reduced smoking rates and better treatment options.

Deaths from stomach cancer have seen one of the most dramatic improvements, dropping by 34 per cent in the past decade. Bowel cancer deaths have decreased by six per cent, while breast cancer deaths have fallen by 14 per cent.

Other cancers have also seen notable declines. Cervical and prostate cancer deaths have both dropped by 11 per cent. Deaths from leukemia are down by nine per cent, while esophageal cancer deaths have fallen by 12 per cent.

Experts say improved diagnosis, new therapies and better awareness are playing a key role in these trends.

Screening And Vaccination Making A Difference

One of the biggest public health successes has been the decline in cervical cancer deaths. Since the 1970s, deaths from cervical cancer have fallen by around 75 per cent in the UK. Health experts attribute much of this progress to the national cervical screening programme run by the NHS.

Screening helps detect abnormal cells early, allowing treatment before cancer develops or spreads.

Another major contributor is the human papillomavirus vaccine, commonly known as the HPV vaccine. The vaccine protects against the virus responsible for most cervical cancer cases. It is routinely offered to schoolchildren in the UK, and since its introduction in 2008, at least 6.5 million young people have received it.

Public health experts believe the vaccine will continue to reduce cervical cancer rates in the coming decades.

Some Cancer Death Rates Still Rising

Despite the overall progress, the data also shows worrying increases in deaths from certain cancers. Gallbladder cancer deaths have risen by 29 per cent, while deaths from eye cancer have increased by 26 per cent.

Liver cancer deaths are up by 14 per cent, and kidney cancer deaths have risen by five per cent. Meanwhile, death rates for thyroid cancer, pancreatic cancer and melanoma have remained largely unchanged.

Another important trend is that the total number of people dying from cancer continues to rise. This is largely due to population growth and an ageing population, as cancer risk increases with age.

Calls For More Research And Clinical Trials

Experts say the long-term decline in cancer deaths reflects decades of medical research and innovation. However, they stress that continued investment is necessary to sustain progress.

Cancer Research UK researcher Dr Sam Godfrey said the figures show the impact of scientific breakthroughs over many years. He has called on the government to support more clinical trials and ensure that NHS staff have enough time and resources to take part in life saving research.

Public health policies such as smoking bans, along with screening programmes and vaccines, are also credited with helping drive down cancer deaths across the country.

Are you in the habit of catching up on social media or news updates while sitting on the pot? A new study shows you may be "unintentionally" spending extra time and increasing your risk of developing painful hemorrhoids by 46 percent.

The study, published in the open-access journal PLOS One, explained that getting distracted by news or social media can increase pressure on sensitive anal tissues, which leads to hemorrhoids.

Hemorrhoids, also called piles, are swollen and inflamed veins around your anus or in your lower rectum.

"Using a smartphone while on the toilet was linked to a 46 percent increased chance of having hemorrhoids. We're still uncovering the many ways smartphones and our modern way of life impact our health,” Trisha Pasricha, from the Beth Israel Deaconess Medical Center in the US.

“It's possible that how and where we use them -- such as while in the bathroom -- can have unintended consequences," she added.

For the study, the researchers examined data from colonoscopies of 125 adults in America, and conducted an online survey to understand their lifestyle habits and behavior while using the toilet.

Two-thirds of the participants reported using their smartphones while on

the toilet. Compared with those who did not, endoscopists found that they had a 46 percent higher risk of hemorrhoids.

Longer Toilet Time And Mobile Scrolling

More than a third of bathroom smartphone users reported spending more than five minutes there during a single visit -- reading news (54.3 percent), or browsing social media (44.4 percent).

In comparison, just 7.1 percent of non-users reported staying that long.

"Smartphone use may unintentionally extend the time people spend sitting on the toilet. Sitting for longer periods could increase pressure on tissues in the anal region, which may contribute to the development of hemorrhoids,” the researchers said.

Pasricha suggested individuals leave smartphones outside the bathroom to understand the actual time it takes for a bowel movement.

"If it's taking longer, ask yourself why. Was it because having a bowel movement was really so difficult, or was it because my focus was elsewhere?" she said, calling for more studies.

Hemorrhoids: The Symptoms, Risk Factors

Studies estimate that hemorrhoidal disease affects 40% of people all over the world, and it is one of the most common diseases in the anorectal region.

The two types of hemorrhoids are:

• external hemorrhoids -- under the skin around the anus
• internal hemorrhoids -- in the lining of the anus and lower rectum

• bright red rectal bleeding during bowel movements,
• anal itching or irritation, pain or discomfort (especially while sitting),
• swelling or hard, tender lumps around the anus

• straining during bowel movements
• sitting on the toilet for too long
• chronic constipation or diarrhea
• eating low fiber foods
• older age >50
• pregnancy
• lifting heavy objects

• consume 25-35g of fiber daily,
• drink 6-8 glasses of water,
• avoid straining,
• limit toilet time to under five minutes
• do not delay bowel movements,
• maintain hygiene.

Iran's capital Tehran was engulfed in a black cloud of toxic smoke. This also unleashed a black rainfall on Sunday after overnight Israeli strikes on several fuel depots caused fires to burn for hours. Images have come from across the city of Tehran. These images show thick black smoke from the fires hanging over it. Residents have also reported difficulty breathing and oil-tainted rainfall staining everything around them.

As per a TIME report, Iran's Red Crescent Society warned the residents of Tehran and the surrounding region that the rainfall after the strikes could be "highly dangerous and acidic", and could cause "chemical burns of the skin and serious damage to the lungs".

Many have complained about breathing problems, along with headache, feeling dry and sore lips, and feeling like burn in the eyes and constant itch in the throat.

What Does The Toxic Rain Fall Contain?

Iran's Red Crescent Society issued statements on Telegram that the rain could be contaminated with "toxic hydrocarbon compounds" as well as "sulfur and nitrogen oxides".

What Are The Health Risks?

As per a report by The Conversation, people exposed to the black smoke in Iran could experience headaches or difficulty in breathing, especially if they have asthma or a lung disease.

People who are more prone to health issues are older people, young children, anyone with disabilities and pregnant women. This could also lead to lower birth weights.

Since the thick black cloud from all the burning could increase the PM2.5 or the ultrafine particles, known as particulate matter, it could also increase cancer risks, along with neurological conditions and cardiovascular conditions.

The toxic rain could further pollute the natural waterways and drinking water sources. A photo shared by Iran's Red Crescent shows a healthcare worker's uniform covered in black droplets from the rain.

The "rain drops" are tainted with oily residue and could lead to skin problems, and if inhaled, it could also lead to serious medical crisis, noted Jim NR Dale, a senior meteorologist at British Weather Services.

It may also carry carcinogenic polycyclic aromatic hydrocarbons (PAHs) along with heavy metals that are released when construction materials burn and then remain suspended in the air.

As acidity increases, natural water bodies such as rivers and lakes can become too hostile to support life. When the pH of water drops below 5, most fish cannot survive, and at pH 4, a lake is often described as a “dead water body” because almost no living organisms remain.

Acid rain also harms the soil. It reduces calcium levels, an important nutrient for plants, and makes it easier for toxic aluminium to leach into water sources, further threatening ecosystems.