For years, moderate alcohol consumption, particularly a daily glass of wine, has been associated with potential health benefits, especially for heart health. However, in recent years, a growing body of research, including warnings from the World Health Organization (WHO) and other health agencies, has highlighted that alcohol poses significant health risks from the very first drink.A recent expert review published in the Journal of Hepatology reiterated this concern, concluding that there is no universally safe level of alcohol consumption.No Universal Safe ThresholdAfter examining recent evidence on alcohol use and health outcomes, researchers from the University of Wisconsin concluded that excessive alcohol consumption is unquestionably harmful and that defining a universally "safe" level of drinking remains unsupported by current scientific evidence.According to the authors, the health risks associated with alcohol vary considerably from person to person. Factors such as age, sex, genetics, underlying medical conditions, medications, and pregnancy status can all influence how alcohol affects an individual's health.Rethinking The "Heart Health" NarrativeAlso read: 844 Million Adults Worldwide Living With Chronic Kidney Disease: Lancet StudyThe researchers also questioned the long-standing belief that moderate drinking provides significant cardiovascular benefits.They found that recent evidence does not support recommending regular alcohol consumption for health purposes. Instead, the review suggests that any potential benefits must be weighed against known risks, including cancer, liver disease, and other alcohol-related harms.Alcohol Linked To 62 DisordersThe review adds to a growing body of evidence linking alcohol consumption to an increased risk of several cancers.A May 2026 study linked alcohol to 62 disorders, ranging from heart and digestive diseases to mental and neurological conditions and cancers.The study, published in the journal Addiction, showed that the fully alcohol-attributable conditions are mainly grouped under non-communicable diseases and injuries.These include:Endocrine, nutritional, and metabolic diseasesMental and behavioral disordersDiseases of the nervous systemDiseases of the circulatory system, such as alcoholic cardiomyopathyDigestive diseasesAlcoholic liver disease and cirrhosisRead More: Emma Barnett: It Took 21 Years To Diagnose My EndometriosisThe data also included psychotic disorders, gastritis, ulcers, pancreatitis, fatty liver disease, pregnancy- and perinatal-related conditions such as fetal alcohol syndrome and fetal alcohol spectrum disorders, as well as external causes and injuries, including alcohol poisoning."These conditions are 100 per cent alcohol attributable, meaning these diseases would not even exist in the world without alcohol use," said Jürgen Rehm, senior scientist at the Institute for Mental Health Policy Research in Toronto and part of the study team, according to CNN."There are another 30 diseases in which alcohol plays a role, such as breast and other cancers, heart disease, stroke, diabetes, and dementia," Rehm said. "These diseases would exist even without alcohol use, but alcohol use is responsible for a certain proportion of them."Global Burden Remains HighThe global burden of alcohol-related health issues is immense. The US National Institutes of Health (NIH) estimated that alcohol-related conditions could cost the United States nearly $1.87 trillion between 2011 and 2050, equivalent to about 1.45 per cent of the country's GDP. The NIH also criticized the lack of clear public messaging, which has allowed myths about alcohol's safety to persist for decades.In 2023, the World Health Organization reinforced this warning. In a statement published in The Lancet Public Health, it declared that there is no safe level of alcohol consumption that does not affect health.