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GLP-1 medications, including the popular brand Ozempic, have made headlines for their dramatic weight loss results. Initially created to treat type 2 diabetes, the medications were a favorite among those wanting to lose weight due to their ability to control hunger. Semaglutide, the active drug found in Ozempic, makes consumers full for extended periods, resulting in significant weight loss in the body. However, with increasing popularity comes an uptick in reports of unusual side effects—some of which are leaving women shocked and bewildered.
Among the most surprising and strange side effects making the rounds among users is what has been colloquially referred to as "Ozempic vulva." The condition involves a reduction of fat in the labia majora, a sagging appearance, pain during routine activities, and alteration of sexual anatomy aesthetics. Although sagging skin and loss of elasticity have long been linked to weight loss, particularly if it occurs rapidly, this particular side effect has only recently emerged.
A Reddit poster posted a first-hand account of experiencing the results for herself. Losing 44 pounds, she at first was jubilant about the outcome. "I've been extremely fortunate and I don't have any sagging skin in my belly or arms/legs that I can notice," she described. But the biggest shock was when she went for a gynecologist appointment. "Turns out I've lost all my fat pads in my vulva! She informed me my vulva is droopy and I will keep on having pain when cycling/sitting unless I undergo surgery or wear fillers," the user posted.
The Redditor also revealed that pelvic floor physical therapy was provided as a substitute for cosmetic intervention, although it would not fully reverse the deflation. Her case highlights the need to be aware of how sudden weight loss, especially from medications such as GLP-1s, can impact lesser-known parts of the body.
Medically, the vulva comprises external female genitalia, mostly the labia minora and labia majora, that act as cushioning protection. Fat loss in this region may cause a greater prominence of the pelvic bones, decrease in cushioning, and pain during exercises like cycling, running, or sitting for extended periods.
The vulva is the external female genitalia, especially the labia majora covering the inner structures. Redditors and users of internet forums have described decreased fat pads in this region after precipitous weight loss caused by GLP-1 medication. One Redditor summed up her experience thus: after losing 20 kg (44 pounds), she developed pain when she cycled or sat for long hours. A gynecologist described losing much of the natural padding around her vulva, leading to a sagging sensation and discomfort during exercise.
Also Read: Ozempic Vulva To Ozempic Smell – Unexpected Ways Of Weight Loss Jabs Change Your Body
This trend, affectionately but aptly called "Ozempop vulva," highlights a singular and seldom-talked-about side effect of weight loss caused by medications. For most women, it's not just aesthetic; it impacts daily comfort, sex, and self-esteem.
Cosmetic treatments have evolved as a result of this trend. "Labia puffing" is an increasingly sought-after procedure for women who experience vulvar deflation. This treatment either involves the use of dermal fillers or fat transfer to add volume to the labia majora, evening out the texture and alleviating discomfort. Though effective, it is quite expensive, between $2,600 and $6,500 in America.
Healthcare professionals are urging caution. Novo Nordisk, the drug maker of Ozempic, reassured the public that patient safety is of utmost priority and assured that the medicines are to be used only for approved use in a medical setting. They also urge reporting side effects to healthcare professionals or regulatory bodies. "Treatment decisions should be made together with a healthcare provider who can evaluate the appropriateness of using a GLP-1 based on assessment of a patient's individual medical profile," said the company.
The larger context of extreme weight loss makes visible the far-reaching consequences GLP-1 drugs can have. Patients experience a range of side effects, from gastrointestinal distress to loose skin, facial fat redistribution, and effects on sexual anatomy and desire. While the physical changes are something to be admired, these effects are a reminder that extreme weight loss is not risk-free.
Incidentally, online discussions of "Ozempic vulva" have become widespread in private online forums and social media sites. Users freely exchange experiences, coping mechanisms, and aesthetic issues. Many recommend practical measures like padded bike shorts or briefer periods of exercise to alleviate discomfort. Others discuss surgical or nonsurgical treatments, although opinions are highly diverse on whether such a procedure would be desirable or required.
Medical professionals emphasize the need for integrated treatment. Sudden loss of weight must be watched over by medical professionals who can advise on likely risks to both general health and particular aspects such as the vulva. Preservation of muscle tone, padding, and elasticity of skin is essential to avoid long-term complications. For women suffering from discomfort, focused physical therapy, proper protective equipment during exercise, and well-informed consideration of cosmetic interventions may all be part of a successful management plan.
Finally, "Ozempic vulva" highlights an increasing trend on the intersection of weight-loss medication and women's health. While the drug has transformed weight control for millions of people, its unintended side effects serve as a reminder that there are risks associated with every medical intervention and that they need to be closely monitored. Education, research, and transparency with healthcare professionals are critical towards preventing such unintended outcomes.
As GLP-1 drugs become more mainstream, patients and providers alike need to be watchful. New side effects such as "Ozempic vulva" demonstrate the importance of full education on the entire range of possible changes wrought by sudden weight loss. Meanwhile, women dealing with these effects are complying with both medical advice and home remedies, being resilient in the face of an odd but increasingly prevalent health issue.
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Flu season has arrived, and while the summer wave of COVID-19 has subsided, a winter increase is expected. Vaccines are available for both viruses, prompting many to ask about timing, especially if they haven’t received their shots yet. With the CDC updating guidelines, rules around vaccination are constantly evolving, so the most common question is: can you get your COVID and flu shots at the same time?
The COVID-19 vaccine can be administered alongside a seasonal flu shot for those who prefer to get both at once. It is considered completely safe. “There are no recommendations against it; it mainly comes down to personal preference,” Dr. Mike Ren, an assistant professor of family and community medicine at the Baylor College of Medicine explained. He added that some people may experience mild fatigue with vaccines, and getting multiple shots at the same time could slightly increase that effect.
Many people are already familiar with how their bodies react to flu and COVID-19 vaccines. The COVID shot can sometimes cause soreness in the arm, so it’s recommended to avoid getting both vaccines in the same arm if that happens. For those who experience minimal side effects, there’s no disadvantage to receiving both shots at the same visit. Some choose to space them out simply based on convenience.
For individuals who have experienced strong reactions to the Pfizer or Moderna mRNA COVID vaccines, the Novavax shot, which uses a more traditional protein-based method may offer an alternative with fewer temporary side effects, according to Caitlin Rivers, an infectious-disease epidemiologist and senior scholar at the Johns Hopkins Center for Health Security.
Males aged 12 to 29 may particularly consider Novavax, as it carries no known risk of myocarditis, a rare heart inflammation sometimes associated with mRNA vaccines. Andrew Pavia, a pediatrics infectious-disease physician at the University of Utah, noted that myocarditis cases linked to mRNA vaccines are generally mild, and COVID-19 itself poses a higher risk of heart complications.
Pavia also explained that there are no major differences between the current Moderna and Pfizer vaccines, so people can choose whichever is more convenient or available.
When Should You Get A Flu Vaccine?
The ideal time to get a flu vaccine is generally from late September through October. Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center, recommends aiming to be vaccinated before Halloween, in line with CDC guidance.
While many pharmacies begin offering flu shots as early as July or August, Dr. Peter Chin-Hong, an infectious disease specialist at the University of California, San Francisco, advises waiting a bit longer. This is because vaccine protection can wane after a few months, and flu cases often peak between December and February.
Even if you miss the early window, it’s still worthwhile to get vaccinated. “Some protection is better than none,” Dr. Chin-Hong emphasizes.
Staying up to date with both COVID-19 and flu vaccinations is an important step in protecting your health during the respiratory virus season. Getting the shots at the same time is safe and convenient for most people, though minor side effects like fatigue or soreness may be slightly increased.
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Researchers from University College London (UCL) have found that quitting smoking may help slow age-related memory decline and protect brain health as we age. According to new research, people who quit smoking in middle age can significantly slow their cognitive decline, so much so that within a decade, their risk of developing dementia becomes nearly identical to those who have never smoked. The study adds to growing evidence that giving up cigarettes can protect brain health and delay age-related mental decline.
Published in The Lancet Healthy Longevity, the study examined data from more than 9,400 adults aged 40 and older across 12 countries. The findings strengthen existing evidence that giving up cigarettes could reduce the risk of dementia, though experts note that further research is needed to understand the full impact of smoking cessation on cognitive health.
Researchers noted that while the link between smoking and poor cognitive health is well known, the long-term effects of quitting have been less certain. In this study, memory and verbal fluency tests showed that people who stopped smoking experienced a slower rate of decline in the six years following cessation.
Experts said the findings are especially important because middle-aged and older adults are often less inclined to quit, despite facing greater health risks. Demonstrating that quitting can also help preserve brain function, they added, could serve as a strong new reason for this group to give up smoking.
Data shows that smoking is most common among adults aged 25 to 34, with about 14 percent identifying as smokers, while only 8.2 percent of those over 65 reported smoking. Responding to the UCL study, Dr. Julia Dudley, head of research at Alzheimer’s Research UK, said smoking is tied to several major health risks, including cancer, heart disease, and dementia—particularly Alzheimer’s and vascular dementia. She emphasized that quitting can greatly lower the likelihood of developing these conditions.
What Is Dementia?
Dementia is an umbrella term for a group of symptoms that affect a person's ability to think, remember, and reason to the point that it interferes with daily life. It is not a normal part of aging, but is caused by damage to brain cells, which can result from conditions like Alzheimer's disease, vascular dementia, or Lewy body dementias. Symptoms include memory loss, confusion, difficulty with language and problem-solving, and changes in mood or behavior, and the condition worsens over time.
Dementia develops when diseases damage brain cells, disrupting how they communicate with one another. This breakdown in communication affects memory, thinking, behavior, and emotions. The brain is made up of different regions, each responsible for specific functions such as judgment, movement, and memory. When cells in a certain area are harmed, that part of the brain can no longer perform normally.
Each type of dementia is linked to damage in particular brain regions. In Alzheimer’s disease, for instance, an abnormal buildup of proteins inside and around brain cells prevents them from staying healthy and transmitting signals effectively. The hippocampus, responsible for learning and memory, is usually the first area affected, which is why memory loss tends to be one of the earliest signs of Alzheimer’s.
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It has been five years since COVID first appeared, and over this period, case numbers have both surged and declined. Suruchi Sood, an assistant professor at Johns Hopkins University in Baltimore, notes that some delays in COVID tracking by the Centers for Disease Control are partly due to the government shutdown. Based on the available data and her own clinical observations, she says, “We don’t seem to be seeing, thankfully, yet, an uptick of COVID.” However, she points out that another respiratory illness is currently gaining ground in the country.
Although COVID-19 cases are declining, many people are still experiencing congestion and sore throats. Dr. Steven Gordon, chairman of the Department of Infectious Disease at the Cleveland Clinic, noted that recent lab data from Northeast Ohio show SARS-CoV-2 activity continuing to fall from its summer peak, with last week’s COVID positivity rate at 5%.
At the same time, infections caused by rhinovirus, the common cold virus, and other enteroviruses have been rising, with a 20% positivity rate. While these numbers are specific to Northeast Ohio, they reflect broader trends reported by the CDC, which show increasing rhinovirus and enterovirus cases as of late September.
Rhinovirus is a widespread virus and the leading cause of the common cold, though it can also trigger other respiratory conditions such as asthma flare-ups, bronchitis, and pneumonia. It spreads through respiratory droplets, direct contact, or contaminated surfaces. While it usually affects the upper respiratory tract, it can sometimes cause infections in the lower respiratory system.
Rhinovirus spreads in several ways, according to the CDC. It can be transmitted through respiratory droplets released when an infected person coughs, sneezes, or talks. The virus can also pass through direct person-to-person contact. In addition, rhinovirus can survive on surfaces such as doorknobs, phones, or other objects for several days, allowing it to spread when someone touches these contaminated surfaces.
As we approach the virus season, it’s important to take steps to protect your health, experts say. Dr. Steven Gordon emphasizes that prevention is better than treatment, recommending the flu shot for anyone older than six months as the most effective protection against influenza. Similarly, getting the COVID-19 vaccine remains the best way to reduce the risk of severe illness and hospitalization.
“With COVID and flu vaccines available, now is an ideal time to get vaccinated, as it takes several weeks for immunity to build,” said Dr. Suruchi Sood. Both vaccines can be administered at the same time and are widely available at pharmacies. It’s advisable to check with your doctor or local pharmacy about COVID shot eligibility in your area.
Maintaining overall health through regular exercise and a nutritious diet can also help defend against respiratory viruses, while frequent handwashing remains a simple but effective preventive measure. COVID vaccination continues to be a safe and effective way to lessen the severity of illness, with recent studies in the VA Health System showing that it reduced hospitalizations, deaths, and emergency visits even in the past season, Dr. Sood added.
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