Shaky hands, trembling arms, and uncontrollable movements—these symptoms tend to often trigger and suspicion of Parkinson's disease. But while Parkinson's is a recognized neurodegenerative disorder, another condition can be responsible for the tremors- Essential Tremor (ET). Although both share some superficial similarities, these two disorders are very different in cause, course, and treatment. And yet, many people struggle with misdiagnosis, delayed treatment, and unnecessary anxiety because of the overlap between them.

With greater awareness and understanding emerging, knowing how to identify differences between Parkinson's disease and essential tremor is more crucial than ever—more important to both patients, families, and doctors. Below's what you have to know about distinguishing between the two and doing something if needed.

What Is Essential Tremor?

Essential tremor is a neurological movement disorder that most often occurs in the hands, but it can affect the head, voice, or legs. Essential tremor is not life-threatening but can interfere with daily activities such as eating, writing, or holding objects, particularly as the disease advances.

It generally appears after age 40, but can arise at any time. The reason is not exactly known, though there is a strong genetic link, with up to 70% of patients having inherited it. Unlike with Parkinson's, ET gets worse with activity rather than rest, and symptoms are worsened by stress, exhaustion, caffeine, and even a change in temperature.

Symptoms include:

• Development of hand tremors gradually, usually beginning on one side
• Shaking that worsens with activity (e.g., drinking, writing)
• Difficulty with fine motor function

In a few instances, involuntary head nodding or voice shaking

What Is Parkinson's Disease?

Parkinson's disease is a chronic neurological disorder that impacts movement and gets worse over time. It happens when dopamine-producing cells in the brain's substantia nigra start to break down, interfering with the brain's ability to manage movement and coordination.

Parkinson's usually starts after the age of 60, although 5–10% of patients start earlier. In contrast to essential tremor, Parkinson's tremors are more prominent at rest and are just one of numerous motor and non-motor signs.

Main symptoms are:

• Resting tremors in hands, legs, jaw, or head
• Muscle stiffness and rigidity
• Slowness of movement (bradykinesia)
• Difficulty with balance and coordination
• Changes in speech and handwriting
• Depression, memory loss, fatigue, and sleep disturbances

Parkinson's vs. Essential Tremor: Essential Differences

While they might appear to be the same, essential tremor and Parkinson's disease are very different in etiology, presentation, and course. Here's a comparison:

Prevalence: Essential tremor is much more prevalent, occurring in as many as 10 million Americans, whereas Parkinson's occurs in about 1 million.

Tremor Type: ET is defined by high-frequency, low-amplitude tremors that are exacerbated by movement. Parkinson's is defined by low-frequency, high-amplitude tremors that are more evident at rest.

Symptom Onset: Symptoms in essential tremor tend to begin slowly and symmetrically, usually in the hands. Tremors in Parkinson's usually begin on one side of the body.

Alcohol Response: Interestingly, ET symptoms will sometimes improve temporarily with alcohol, but this is not a therapy. Parkinson's symptoms do not typically respond to alcohol.

Associated Symptoms: Parkinson's involves a broader variety of symptoms, including stiffness of the muscles, walking difficulties, and changes in the cognition that are generally not seen in ET.

Diagnosing the Difference

Since both diseases can start subtly and present with similar symptoms, diagnosis is frequently difficult. Physicians rely on neurological examinations, review of the medical history, and in some cases, brain imaging to make the differentiation between the two.

Regrettably, there isn't a test that can absolutely diagnose Parkinson's disease or essential tremor. They are frequently misdiagnosed, especially at early stages, and thus improperly treated or given delayed appropriate care.

Complicating matters further, there are some other neurological disorders that closely resemble Parkinson's disease, making diagnoses even more difficult. These include:

Multiple System Atrophy (MSA): Poor coordination and slurred speech

Lewy Body Dementia: Merges movement symptoms with memory loss and hallucinations

Progressive Supranuclear Palsy (PSP): Disrupts eye movement and balance

Corticobasal Degeneration (CBD): Increases in severity on one side of the body, includes speech and swallowing problems

Each disorder needs a distinctive treatment strategy, which underscores the value of proper diagnosis.

Who Is Most Susceptible to Developing These Condition?

Parkinson's disease is more frequently diagnosed in men, and the risk becomes much higher after 60 years. Most cases are sporadic, but in some, a genetic tendency is observed, particularly among persons with a history of the condition in their family. Environmental factors like long-term exposure to certain toxins and pesticides have also been shown to increase the risk of Parkinson's disease.

Essential tremor, however, can arise at any age but usually starts beyond the age of 40. It is highly hereditary, and approximately 50–70% of patients report a family history. Unlike in Parkinson's disease, there are no identified environmental triggers for essential tremor to date.

When to Seek Help?

Essential tremor is in most cases mild and controllable, but any worsening or disrupting tremor must be assessed by a neurologist. Treatment of both conditions involves medication, physical therapy, and sometimes deep brain stimulation (DBS). Early diagnosis, lifestyle changes, and professional help can significantly enhance the quality of life.

If you're having tremors, don't try to diagnose yourself or search online. Instead, see a neurologist who can steer you in the direction of the correct diagnosis and individualized treatment plan.

Parkinson's disease and essential tremor can have overlapping symptoms, but they are two different conditions with different causes, courses, and treatments. Understanding the differences—and getting timely medical guidance—can help people take charge of their health.

In a world where small symptoms can be misinterpreted, clarity is key. Whether it’s a slight hand tremor or noticeable movement change, paying attention to your body and getting the right diagnosis can make all the difference.

Each year, hundreds of people around the world lose their lives waiting for a life-saving organ transplant. The demand for organs far outweighs the supply, leaving many patients with little hope. But what if we could print organs—tailor-made for each patient—using their own cells? While we're not quite there yet, researchers are making significant strides in this futuristic field known as 3d bioprinting.

Though the technology is still far from clinical trials, scientists believe that when 3d-printed organs become a medical reality, the process will likely involve a blend of cutting-edge imaging, personalised cell harvesting, and highly advanced bioprinting methods. Here's what this groundbreaking process could look like.

Step 1: Creating a Personalised 3D Model

To print a functional organ, the process begins with creating a precise 3D blueprint. While generic models can serve as a starting point, personalisation is key. Using imaging technologies like MRI (Magnetic Resonance Imaging) and CT (Computed Tomography) scans, medical professionals can generate a detailed digital model of the organ tailored specifically to the patient’s anatomy. This personalized design enhances the chances of a successful transplant by ensuring the printed organ will fit and function properly in the recipient’s body.

Step 2: Collecting Patient’s Cells And Preparing Bioink

One of the biggest hurdles in organ transplantation is rejection, which happens when the recipient’s immune system attacks the new organ. To reduce this risk, scientists aim to use the patient’s own cells to build the organ. These cells are harvested, cultivated in labs, and combined with a specially designed “bioink”—a gel-like substance engineered to mimic the structure of natural tissues. This bioink becomes the medium through which living cells can be precisely layered and formed into complex biological structures.

Step 3: Printing the Organ

With a personalized 3D model in hand and a supply of bioink rich in the patient’s cells, the actual printing process begins. The organ is built layer by layer, using bioprinters designed to handle delicate biological material. Some methods involve extrusion-based bioprinting, which pushes the bioink through a nozzle to form a structure, similar to how icing is piped onto a cake. Other techniques rely on light-based bioprinting, which uses beams of light to shape the biomaterial with incredible precision.

In some cases, additional cells may be added to the organ after printing to support its development or enhance functionality. Although the exact tools and materials are still being refined, technologies such as the BIO X, BIO X6, and LUMEN X are among those helping to push the boundaries of what’s possible in tissue engineering.

Road Ahead

While researchers are still navigating numerous scientific and ethical challenges, the vision of printing fully functional, transplantable organs is no longer science fiction. With continued innovation and global collaboration, 3D bioprinting could one day eliminate organ shortages altogether, saving countless lives and revolutionizing modern medicine.

In a world where superfoods, supplements, and scientific advances define the health discourse, María Antonia Cuero's story shines for its elegant simplicity. At 123, María is officially the world's oldest living human—informally surpassing the Guinness World Record holder, France's Jeanne Louise Calment, who reached 122 years of age. Though her age remains in process of verification, the insights she offers are incontrovertibly priceless and scientifically validated.

Born on October 18, 1901, in Colombia, María has witnessed two world wars, numerous technological revolutions, and the dawn of modern medicine. Yet when asked what the secret to her remarkable longevity is, María doesn't refer to a magic pill or a genetic mutation. Rather, she attributes her longevity to two humble foods: fish and bananas—cornerstones of her daily diet, steeped in her coastal upbringing.

Growing up in a big family of 10 siblings by the Mayorquín River, María spent her days surrounded by nature. With fresh fish and tropical fruits readily available, her childhood diet was both organic and full of nutrients—years before these words became health buzzwords. Throughout the decades, she also raised eight children and is now the proud matriarch to 26 grandchildren, 24 great-grandchildren, and 54 great-great-grandchildren.

Although not officially documented by the Guinness World Records, María's identification card in 2012 indicates her birth as October 1901. She became the oldest to get vaccinated in March 2021, at 119 years old, marking yet another incredible achievement to her name.

However, aside from age and figures, it is María's way of living and attitude that provide deep insights into longevity.

Maria's Mindset and Philosophy of Longevity

In an interview on the Colombian television show Los Informantes, María discussed her philosophy of life: laugh frequently, don't worry excessively, remain active, and don't sit around too much. In her opinion, physical activity is essential. Her regimen included walking often, swimming, rowing, and being outdoors—long before fitness monitors or gym memberships were the rage.

These principles echo research in contemporary gerontology. Many studies identify an active life and good social relationships with a lower risk of chronic disease and longer lifespan. María's case supports that emotional well-being, combined with activity, is significant in healthy aging.

Fish

Of all the foods that she ate, fish is what María puts so much stress on. Living next to the river as a child, not only was she afforded the fresh catches each day, but she fished herself very frequently. "Good fish. I would fry the fish and then mix it with coconut and rice," she shared with a journalist.

Fish is a good source of high-quality protein, omega-3 fatty acids, vitamins D and B2 (riboflavin), and minerals like calcium, phosphorus, iron, zinc, iodine, magnesium, and potassium. Omega-3s in oily fish, particularly docosahexaenoic acid (DHA), are recognized to lower inflammation, maintain brain health, and decrease the risk of heart disease.

Scientific studies in the Journal of the American Medical Association have indicated that individuals with high levels of omega-3s live as much as 2.5 years longer on average. Another significant study identified a 40% lower risk of coronary heart disease mortality in those who ate regularly from fish with high levels of omega-3s, a figure further supported by the British Heart Foundation.

Bananas

María's second pillar of diet? Bananas—the smaller, sweeter bocadillo bananas (also referred to as sugar bananas or lady finger bananas). These bite-sized fruits are not only tasty but are full of fiber, antioxidants, potassium, and vital vitamins.

Bananas have been valued for centuries for their digestive and cardiovascular benefits. They help to control blood pressure, balance body fluids, and repair muscle and nerve tissue—all highly beneficial for elderly populations. The tryptophan and vitamin B6 contained in bananas also assist with serotonin formation, the "feel-good" neurotransmitter that enhances emotional well-being.

For María, these bananas were an everyday treat. And as science indicates, eating bananas on a regular basis can help with heart health, boost mood, and assist with muscle recovery.

What We Can Learn From Her Habit?

María's remarkable life is not merely about what she ate—it's about the regularity with which she lived. Her life was based on balance: a modest diet, regular exercise, a positive attitude, and close family ties. To this day, she radiates resilience. When asked what she is afraid of, her answer was moving: "I am not afraid of anything anymore."

This lack of fear and deeply ingrained calmness may also have protective health benefits. Studies have linked chronic stress to increased inflammation and a heightened risk of age-related diseases. María’s philosophy—“don’t worry too much”—may offer more protection than we’ve previously realized.

As the world population ages, María Antonia Cuero's life is an eloquent reminder: the route to longevity may not come in the form of costly therapies, restrictive eating, or vigilant self-tracking. It may sometimes be found in age-old secrets—eat fresh, move frequently, laugh without restraint, and enjoy the little things.

As we wait for official verification of her record-setting age, her legacy already walks tall as an example of how simplicity, persistence, and culture can overcome and thrive. In a world filled with constantly changing health fads, María's legacy encourages us to stop for a moment and ask—what really counts when it comes to living a long, healthy life?

Microplastics—those invisible particles of plastic pollution—may be doing more than just contaminating the environment. According to recent findings presented at the American Heart Association (AHA), they could also be silently contributing to clogged arteries, potentially raising the risk of heart attacks and strokes.

In a study that’s turning heads in the medical community, researchers discovered that fatty plaques found in neck arteries—known as carotid arteries—contained over 50 times more microplastic content compared to plaque-free arteries. Even more concerning, these microplastic concentrations were found to be significantly higher in individuals who had already suffered from a stroke, mini-stroke, or temporary vision loss caused by restricted blood flow.

What Exactly Are Microplastics?

Microplastics are extremely small particles—often less than five millimeters in size—created when larger pieces of plastic break down. They can enter the human body in multiple ways: through the air we breathe, the food we eat, and even skin contact. An even smaller subset, known as nanoplastics, measures under 1,000 nanometers and is completely invisible to the naked eye. Because of their minuscule size, these particles can infiltrate tissues, organs, and potentially disrupt biological functions.

The accumulation of microplastics in arterial plaques introduces a new dimension to the ongoing conversation about cardiovascular risk factors. While high cholesterol, smoking, and hypertension remain the usual suspects, environmental pollutants like microplastics are emerging as a stealthy but significant threat.

A Simple Solution In Your Kitchen?

Amid growing concerns about microplastic contamination, especially in drinking water, scientists have been working on practical ways to mitigate exposure. In 2024, a research team from Guangzhou Medical Centre made a breakthrough. They discovered that a common household activity—boiling water—can significantly reduce microplastic content in tap water.

According to the team, combining boiling with basic filtration can remove up to 90% of nanoplastic and microplastic particles (NMPs) from household water. However, the method’s effectiveness varied depending on the type of water used. In areas where tap water contains higher mineral content, commonly referred to as "hard water," the technique proved especially efficient.

The secret lies in limescale. As hard water is heated, it forms limescale—a chalky white substance—which appears to create a sticky layer that traps microplastic fragments. Researchers found this natural process enhanced the removal of plastic particles from water, offering a practical and affordable solution for most households.

While more research is needed to fully understand the long-term health effects of microplastics, early evidence suggests they may be more dangerous than previously thought—especially for cardiovascular health. Taking simple precautions, such as boiling and filtering drinking water, could help reduce exposure and offer a small but meaningful step toward safeguarding your heart and overall well-being.