Cancer is a life changing disease, and while cancer in itself can induce anxiety in many, there are rare cancers, which may further escalate that fear. Rare cancers are types of cancers with low annual incidence, and are generally defined as fewer than 6 cases per 100,000 people. While it is infrequent, over 200 types of rare cancers are still represented by a significant portion of all cancer cases and deaths, presenting unique challenges for prevention, diagnosis, and treatment due to the scarcity of research as well as expertise.

Among the rare cancer, is a category, often referred to as 'silent diseases', because many of the early symptoms are often dismissed. These are gynecological cancers. According to the American Cancer Society, more females are diagnosed with gynecologic cancer in 2024 than colon cancer.

Also Read: If You're Alone At Home And Experience A Heart Attack, Here's How You Survive: According To Doctor

Rare Gynecologic Cancers That Exists

Rare gynecological cancers include primary fallopian tube cancer, primary peritoneal cancer (similar to ovarian cancer), gestational trophoblastic disease (GTD), and specific subtypes of more common cancers like clear cell ovarian carcinoma or certain cervical cancers. These cancers, which originate from parts of female reproductive system or associated tissues, are distinct from the more common types and thus require specialized diagnosis and treatment.

Fallopian tube cancer: It starts in the tubes connecting the ovaries and uterus. It makes up to 1 to 2% of gynecologic cancer, and less than 1% of all reproductive organ cancer with 1,500 to 2,000 cases reported worldwide, and of them 300 to 400 are annually diagnosed in the US.

Gestational trophoblastic disease: It forms in the layer of cells that encloses an embryo in pregnant women. It affects about 1 in 1,000 pregnancies in the US.

Primary peritoneal cancer: Forms within the tissue that lines a woman's abdominal and reproductive organs. It affects fewer than 7 cases per 1 million people annually. Researchers also suggest that of the 15% women diagnosed with advanced ovarian cancer may have primary peritoneal cancer. It also effects women over the age of 60.

Uterine sarcoma: Begins in the muscles or soft tissues of the uterus. They are rare, and represent about 1% of all female genital tract malignancies and 3 to 7% of uterine cancers.

Vaginal Cancer: Starts in the vagina and spreads to the external genitals. It is mostly common among women at their older age, especially around 69 years old. It makes up to 1 to 2% of gynecologic cancer.

Vulvar Cancer: Affects the outer part of the female genitals. There is a 1 in 333 chance of being diagnosed with vulvar cancer, but makes up to 6% of new gynecologic case.

What Are The Common Symptoms Of Gynecologic Cancer?

It can be detected early with regular pelvic exams and Pap tests.

Read: What To Expect From A Pap Smear Test?

The common symptoms to note for so you can see your doctor are:

• Unusual bleeding or discharge
• Sores, lumps, or growths
• Persistent itching or burning
• Tenderness or pain, especially during sex or urination
• Changes in skin color
• Constipation or other changes to bowel movements and urination
• Swollen abdomen

How Can It Be Diagnosed?

A pelvic Examination is one of the ways to diagnose it. This is when the doctor looks at the inside of the vagina and cervix. Pressing ovaries and uterus to check for abnormalities is also part of this examination.

During a pap test, the doctor collects cells from the cervix and looks at it under a microscope. In colposcopy, a magnifying device called a colposcope is used to spot suspicious tissue. In a biopsy, a small tissue sample is extracted for analysis under a microscope and a doctor will look for cancer cells. Lastly, MRI or CT scans and ultrasounds can be used as imaging techniques to locate tumors and see if cancer has spread.

Vitamin C is a star ingredient in the skincare world for some very good reasons. It can be hailed as a magic wand to evaporate your stubborn marks and give you a brighter complexion.

However, no matter what product you use, the results do not appear overnight. So, what do real results look like? What does a before-and-after journey of using a Vitamin C serum actually entail?

This guide covers everything about the before-and-after results of using the Vitamin C serum.

What Is Vitamin C Serum and How Does It Work on Skin?

It is a potent antioxidant that can be applied to your skin directly. It neutralises the effects of free radicals, which are tiny and unstable molecules caused by pollution and UV rays. They can easily damage your skin and accelerate ageing.

Vitamin C helps by boosting collagen production and improving skin tone. This is why the results of Vitamin C on the face are so dramatic. It changes the flat look of your skin to a healthy glow.

Key benefits include:

· Brightening: It blocks the enzyme responsible for producing pigment, leading to more radiant skin.

· Fading Marks: A remarkable ingredient for targeting sun damage and acne scars.

· Collagen Stimulation: It keeps your skin bouncy and firm.

· Protection: It provides a second layer of defence against environmental stress.

Before and After Vitamin C Serum: What to Expect on Your Face

Consistent use of the serum for several weeks, along with daily application of sunscreen with SPF 50 can yield noticeable results. Here’s what you can expect from it.

Before Using Vitamin C Serum

Your skin may show signs of environmental wear and tear before you start using a serum. The following are some common complaints:

· Your skin looks tired, even after a full night's sleep.

· You may have patchy skin or dark areas around the mouth and forehead.

· Old acne spots or sun freckles that refuse to fade.

· Skin that feels slightly rough or looks congested.

After Consistent Use

The changes in your face before and after using a vitamin C serum become evident after your skin integrates the serum into its renewal cycle:

· It will give you that lit-from-within look.

· Dark spots become significantly lighter and blend into your natural skin tone.

· Your skin feels more elastic and youthful due to increased collagen.

· The surface of your skin looks smoother.

Timeline of Vitamin C Serum Before and After Results

First Week: Initial Freshness & Surface Glow

There is little change in dark spots during the first few days. However, you may notice an immediate glow on your skin surface. The serum hydrates and smoothens the skin's surface, helping makeup sit better. Vitamin C for dark spots before and after signs are clearly visible.

2–4 Weeks: Brightening & Early Spot Lightening

You will start to see the before-and-after progress of vitamin C on dark spots around this stage. Its pigment-blocking properties start to kick in. You may notice that your overall skin tone looks fresher and that the edges of your dark spots are now fading.

4–8 Weeks: Visible Even Tone and Improved Texture

The difference between your face before after vitamin C serum will be more obvious by the end of the second month. The deeper layers of the skin benefit from the antioxidant protection. You can expect the following changes:

· Visibly less sun damage

· Even complexion, so you may not need concealer

· Fewer rough patches

8–12 Weeks: Long-Term Transformation

After 90 days, your skin has gone through multiple renewal cycles. Your Vitamin C serum before-and-after photos may show significant improvement in hyperpigmentation. Fine lines may reduce because of the increased collagen, as your skin looks the healthiest it has in years.

Tips to Maximize Your Vitamin C Serum Before and After Results

If you want your before-and-after vitamin C serum results to be impressive, you need to follow these simple rules:

1. Morning is Best: Apply your serum in the AM. This allows the antioxidants to protect your skin from pollution and sunlight throughout the day.

2. Pair with Sunscreen: Always follow up with a sunscreen. Vitamin C is not a replacement for sunblock, but it actually makes your sunscreen with SPF 50 more effective by neutralizing the rays that slip through.

3. Storing the Serum: Vitamin C is sensitive to light and air. Keep your bottle in a cool, dark place (such as a drawer) to ensure it does not lose its potency. If your serum has become dark or orange in colour, it may have been oxidised. So, it may not work well.

4. Consistency: You do not need a huge amount of serum. 3–4 drops are enough. You need to apply it every single day without skipping.

Final Thoughts

The journey of your face before and after Vitamin C serum can feel long, but the results are worth it. It can be exciting to see the initial glow. However, the real changes, such as fading deep dark spots and firming the skin, take time. Stick to a routine and pair your skin with a high-quality sunscreen to stay radiant and youthful.

The Healthandme team was not involved in authoring this story

Scientists say they have uncovered the first strong evidence that a specific type of brain training could meaningfully reduce the risk of Alzheimer’s disease. The findings come from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study, a large US clinical trial that followed 2,802 healthy adults aged 65 and older for 20 years. Published in Alzheimer’s & Dementia: Translational Research & Clinical Interventions, the research found that participants who completed a targeted “speed of processing” brain training programme, along with booster sessions, had a 25 per cent lower risk of developing dementia compared to those who received no training.

Why This Matters

Dementia remains one of the most pressing health challenges worldwide. In the UK alone, around 900,000 people live with the condition, with Alzheimer’s disease being the most common form. There is currently no cure. While newer drugs may modestly slow cognitive decline for some patients, they do not stop or reverse the disease.

That is why prevention, or even delay, is so crucial. Even pushing back the onset of dementia by a year or two across the population could significantly reduce strain on families, healthcare systems and social care services.

Lifestyle factors already play an important role. Regular exercise, managing blood pressure and diabetes, avoiding smoking and staying socially active are all linked to lower dementia risk. Now, this new research suggests that certain types of structured mental training may also help.

Inside the ACTIVE Study

Back in the late 1990s, researchers randomly assigned older adults to one of four groups:

• Speed-of-processing training
• Memory training
• Reasoning training
• No training (control group)

Each participant attended ten hour-long sessions over five to six weeks. Some who completed most of the sessions were later randomly selected to receive additional “booster” sessions about 11 months later and again after 35 months. In total, participants completed between 10 and 22½ hours of training spread over three years.

Memory training focused on mnemonic techniques. Reasoning training involved identifying patterns and solving structured problems. But it was the speed-of-processing training, delivered through a computer-based programme, that stood out.

The Brain Game That Made a Difference

One of the key exercises, called Double Decision, required participants to quickly identify a central object (like a specific car) while simultaneously locating a road sign that briefly flashed in their peripheral vision. As players improved, the images appeared for shorter periods, increasing difficulty.

The best possible score in the game was 32 milliseconds. The average score hovered around 100 milliseconds, but participants who stuck with the programme often improved to about 50 milliseconds — nearly doubling their processing speed.

Unlike memory drills, this training targeted how quickly and accurately the brain processes visual information — a skill that tends to decline with age.

What Happened Over 20 Years?

Researchers tracked participants’ health records to see who was later diagnosed with Alzheimer’s disease or related dementias. Nearly half of the control group developed dementia during the two-decade follow-up.

The same held true for those who received memory or reasoning training.

However, the group that completed speed training and received booster sessions had a strikingly different outcome: their risk of dementia diagnosis was 25 per cent lower than the control group.

A Note of Caution

The researchers themselves urge caution. The people who benefited most were those who completed the initial sessions and returned for boosters. It’s possible that these individuals were already more motivated, healthier, or cognitively stronger — factors that may independently reduce dementia risk.

To address this, booster sessions were randomly allocated among eligible participants, and analyses adjusted for age, education, baseline cognitive performance and other health factors. Still, no statistical method can completely eliminate the possibility that the most engaged participants were also those most likely to stay healthier longer.

Henry Mahncke, chief executive of Posit Science — the company behind the training software — described the results as “astonishing” and potentially transformative for brain health.

The academic authors, including researchers from Johns Hopkins School of Medicine, the University of Pennsylvania and the University of Washington, were more measured. They concluded that speed-of-processing training “has the potential to delay the diagnosis” of Alzheimer’s and related dementias — but further research is needed.

If confirmed, the implications could be profound. The idea that even later-life brain training might buy people more time before dementia sets in offers a rare note of hope in a field where breakthroughs are hard won.

Can Chinese medicine cure baldness? Baldness has long been dealt as a matter of shame over health. Products focus on hiding the bald patch rather than curing it. Baldness has in the past made global headlines when South Korean president Lee Jae Myung said 'Baldness is the new enemy' and suggested that insurance should cover the treatment as a part of medical treatment.

Read: South Korean President Says Baldness Is The 'New Enemy'; Wants Insurance To Cover Hair Loss Treatment

Androgenetic alopecia (AGA), better known as pattern hair loss, is the most common form of hair thinning worldwide. While medications like finasteride and minoxidil remain the standard line of treatment, concerns around side effects, lifelong use, and mixed results have led many people to explore gentler, more holistic alternatives.

A new scientific review now suggests that Polygonum multiflorum—a root used in traditional Chinese medicine for over a thousand years—may hold real promise in managing AGA. Historically described as a remedy that can “blacken hair and nourish essence,” the herb is gaining renewed attention as modern research begins to unpack how it actually works at a biological level.

A Multi-Pathway Approach to Hair Health

Most conventional hair-loss treatments target a single biological mechanism. Polygonum multiflorum, however, appears to work on several fronts at once. According to the review, the herb helps reduce the activity of dihydrotestosterone (DHT), a hormone strongly associated with hair follicle shrinkage in AGA.

At the same time, it protects hair follicle cells from premature cell death and activates key growth-related signalling pathways, including Wnt and Sonic Hedgehog (Shh), both crucial for maintaining a healthy hair growth cycle. The herb may also improve scalp blood circulation, potentially enhancing the delivery of oxygen and nutrients to hair follicles—an often overlooked factor in hair thinning.

Ancient Records Meet Modern Biology

“Our analysis bridges ancient wisdom and modern science,” said Han Bixian, the lead author of the review published in the Journal of Holistic Integrative Pharmacy. “What surprised us was how consistently historical texts—from the Tang Dynasty onward—described effects that align closely with today’s understanding of hair biology.”

The researchers examined a wide range of evidence, including laboratory studies, clinical observations, and historical herbal literature. Together, these sources suggest that Polygonum multiflorum does more than simply slow hair loss—it may actively support healthier hair function.

Beyond Slowing Hair Loss

One of the most striking findings is the herb’s potential role in hair regeneration. Rather than only delaying further thinning, Polygonum multiflorum appears to influence multiple growth factors involved in restarting and sustaining the hair cycle. This broader mode of action could give it an edge over treatments that focus on just one biological target.

Safety, Processing, and What Comes Next

The review notes that when properly processed—a critical step in traditional preparation, the herb shows a relatively favorable safety profile. This could make it more appealing to patients concerned about side effects such as sexual dysfunction or scalp irritation commonly linked to existing medications.

That said, the authors stress the need for more high-quality clinical trials to confirm effectiveness, establish safe dosing, and standardize preparation methods. Even so, the findings highlight how rigorous scientific study of traditional remedies can uncover new possibilities for treating common conditions like androgenetic alopecia.