The NHS has issued fresh advice for people taking a widely prescribed medicine used to manage heart and circulation conditions. Across the UK, millions rely on beta-blockers to treat heart and blood vessel problems. Each year, more than 50 million prescriptions are written for these drugs, which help manage issues ranging from high blood pressure and abnormal heart rate to certain conditions affecting the brain and nervous system. Doctors most commonly prescribe bisoprolol, which NHS England lists as the seventh most prescribed medicine in the country.What Is Bisoprolol Used For?Bisoprolol, sold under brand names such as Zebeta, Bisotab, and Concor, belongs to a group of medicines called beta-blockers. It is mainly used to treat various heart-related conditions by slowing the heart rate and relaxing blood vessels. This reduces strain on the heart and helps it pump blood more efficiently, according to the CDC. The NHS also explains that bisoprolol is used to prevent chest pain caused by angina and to manage atrial fibrillation and other irregular heart rhythms. By slowing the heart, it allows the heart muscle to work more effectively.Data from 2024–25 shows that bisoprolol was dispensed around 32 million times in England alone. The NHS notes that for people with high blood pressure, taking bisoprolol can help lower the risk of future heart disease, heart attacks, and strokes.Bisoprolol Side Effects: Why Is NHS Warning Against Bisoprolol?Like most medicines, bisoprolol can cause side effects, and patients are advised to stay alert to them. People starting the medication are often told to take their first dose at night, as it can make some feel dizzy. There are several common side effects that affect more than one in 100 people. According to the NHS, these are usually mild and tend to settle over time. They include:feeling dizzy or sickheadachescold hands or feetconstipationdiarrhoeaHowever, there are less common but more serious side effects that should not be ignored, as they may require urgent medical attention. The NHS advises contacting a doctor or calling 111 if:you experience shortness of breath with a cough that worsens during physical activity, swelling in the ankles or legs, or an irregular heartbeat, as these can point to heart problemsthe whites of your eyes or your skin turn yellow, which may be harder to notice on darker skin tones, as this can signal liver issuesBisoprolol Warning: When Should You See Medical EmergencyThe NHS also urges people to seek immediate help if certain symptoms appear. These include:chest pain, which could indicate heart troubleshortness of breath, wheezing, or tightness in the chest, which may suggest lung-related problemsEmergency services should be contacted straight away if there are signs of a severe allergic reaction, known as anaphylaxis. The NHS says to call 999 immediately if:your lips, mouth, throat, or tongue suddenly swellyou are breathing very fast or struggling to breathe, with wheezing or a choking sensationyour throat feels tight or you have difficulty swallowingyour skin, lips, or tongue turn blue, grey, or pale, which may be more visible on the palms or soles in people with darker skinyou suddenly feel very confused, extremely drowsy, or dizzysomeone collapses and cannot be wokena child becomes limp, floppy, or unusually unresponsive, with difficulty holding their head up or focusingThe NHS stresses that while bisoprolol is effective and widely used, knowing when side effects are harmless and when they signal an emergency is key to staying safe.