You've heard of "clogged arteries," but do you truly understand what is going on in your body? It's not merely a matter of consuming too many cheeseburgers. Something known as atherosclerosis—a gradual, insidious accumulation of plaque composed of cholesterol, fats, calcium, and other materials—lies beneath the surface, often the true cause of heart attacks and strokes.

Cardiovascular disease is still among the biggest killers globally, and a lot of the risk comes from its invisibility. Atherosclerosis, which is sometimes referred to as the silent killer, slowly plugs up arteries and lays the groundwork for heart attacks and strokes well before they manifest. The best news? With the proper information and preventive actions, you can shield your arteries and heart.

This is the thing: this toxic buildup doesn't present symptoms until it has already done substantial harm. Cardiovascular disease, says the American Heart Association, is the number one cause of death worldwide, and atherosclerosis is at the center of the epidemic.

But the good news is: atherosclerosis can be prevented, even reversed in some instances—if you know how it comes about, how to detect its signs early on, and what changes in lifestyle can actually safeguard your heart.

What is Atherosclerosis?

Atherosclerosis is a disease where plaque accumulates on the arteries' walls. This plaque is composed of cholesterol, fat, calcium, and other substances moving through the blood. Eventually, these deposits harden and constrict the arteries, decreasing blood supply to organs.

"Atherosclerosis is a devious, even lethal illness wherein artery walls get clogged with plaque," describes Dr. Paneendra S, Orthopedic Surgeon. "Atherosclerosis develops over the course of many years and usually is without symptoms until it leads to a life-threatening event such as a heart attack or stroke."

The illness usually starts when the lining of the arteries inside, the endothelium, is damaged. A number of reasons are responsible for this damage, such as:

• Smoking
• High cholesterol
• Diabetes
• High blood pressure
• Chronic inflammation

"Once the endothelium has been hurt, LDL (low-density lipoprotein) cholesterol can filter through the arterial wall," says Dr. Paneendra. "White blood cells rush in to break down the cholesterol, but this reaction creates fatty nodules called atheromas."

These atheromas may develop and then rupture, producing clots that either occlude the artery in which they were formed or embolize to a different location within the body, obstructing an organ elsewhere.

Warning Signs and Where They Appear

Although dangerous, atherosclerosis typically develops silently. Its warning signs first become apparent only when blockage is complete. Depending on the arteries involved, the signs are variable:

Heart (Coronary Arteries): Chest pain or discomfort, also referred to as angina.

Legs (Peripheral Arteries): Pain that occurs during walking (claudication), numbness, or non-healing sores.

Brain (Carotid Arteries): Slurred speech, numbness, or weakness—often stroke warning signs.

Feet and Toes: Burning, color changes, or chronic ulcers caused by inadequate circulation.

These symptoms indicate that one of the primary arteries has already experienced extensive narrowing or blockage. Early treatment and control are important to avert permanent damage.

Role of Inflammation and Lifestyle For Heart Damage

Chronic inflammation is a key contributor to the formation of atherosclerosis. Obesity, lack of exercise, and dietary factors cause chronic inflammation, which further accelerates arterial damage.

The diet rich in saturated and trans fats raises the level of LDL cholesterol, while fruits, vegetables, and fiber intake ensures your body has natural ant-inflammatory power.

How You Can Prevent This Life-Threatening Heart Condition?

Because atherosclerosis progresses silently, prevention is more important. Here's how you can regain control of your heart health:

1. Eat a Heart-Healthy Diet

Emphasize whole grains, leafy greens, berries, nuts, and healthy fats such as olive oil. Reduce your intake of processed foods, red meat, and sweetened drinks.

2. Exercise Regularly

Strive for at least 150 minutes of moderate aerobic exercise a week, including brisk walking, cycling, or swimming.

3. Quit Smoking

Smoking is one of the most significant risk factors. Quitting dramatically reduces the risk of arterial plaque buildup.

4. Manage Stress

Chronic stress can raise blood pressure and trigger inflammation. Practice mindfulness, yoga, or deep breathing techniques.

5. Monitor Blood Pressure and Cholesterol

Routine health checkups can help detect high cholesterol or hypertension early, allowing for timely intervention.

6. Control Blood Sugar

For individuals with diabetes or prediabetes, blood sugar control is essential to minimize inflammation and artery damage.

When to Seek Medical Help?

Even if you don't have symptoms, if you have several risk factors—like a history of heart disease in your family, smoking, or high cholesterol levels—it's crucial to see a healthcare professional. Tests for screening purposes such as cholesterol panels, blood pressure checks, and even coronary calcium scans can evaluate your risk.

"Overall, atherosclerosis is frequently unsuspect, progressive disease that can be severely damaging to cardiovascular health," cautions Dr. Paneendra. "Because symptoms only typically appear after widespread damage, early detection and prevention are critical."

Dr. Paneendra S is an Orthopedic Surgeon at Apollo Spectra Hospital, Bangalore in India

Every night when we fall asleep, the brain does not simply power down. Instead, it moves through a carefully organized biological rhythm known as the sleep cycle. During this process, the body shifts through different stages of sleep that help repair tissues, regulate emotions and strengthen memory.

Scientists have spent decades studying these stages using brain recording tools such as electroencephalography, or EEG. This technique measures electrical activity in the brain using small sensors placed on the scalp. By analyzing these signals, researchers can identify exactly which stage of sleep a person is in.

According to multiple National Institutes of Health studies, sleep occurs in repeating cycles of two kinds: Non Rapid Eye Movement sleep (NREM) and Rapid Eye Movement sleep (REM). A typical cycle lasts about 90 minutes and the brain repeats this cycle four to six times each night.

The Structure Of The Sleep Cycle

NREM sleep includes three stages, moving from light sleep to deep sleep. After these stages, the brain enters REM sleep, which is strongly linked to dreaming and emotional processing.

Scientists believe the repeated movement through these stages helps the brain complete different biological tasks. Some stages repair the body while others reorganize information learned during the day.

Neuroscientist Jan Born, University of Tübingen, whose research focuses on sleep and memory, explains that deep sleep is essential for memory formation. His work shows that during sleep, the brain transfers information from short term storage to long term memory systems.

Stage 1: The Transition Into Sleep

The first stage, called NREM Stage 1, is the moment when the brain begins shifting from wakefulness into sleep. This stage typically lasts only a few minutes. Muscles relax, breathing slows slightly, and eye movements become slower. Brain waves also begin to change.

When we are awake, the brain produces fast electrical signals called beta waves. As sleep begins, the brain switches to slower patterns known as theta waves.

Because this stage is very light, a person can wake up easily. Many people experience sudden muscle twitches known as hypnic jerks, which can feel like the sensation of falling.

Stage 2: Stable Light Sleep

NREM Stage 2 is where true sleep begins. This stage usually makes up the largest portion of the night. During this stage, the heart rate slows and body temperature drops slightly, preparing the body for deeper rest.

Brain recordings show unique patterns called sleep spindles and K complexes. Sleep spindles are short bursts of rapid brain activity. A 2011 Neuroscience study found that these spindles are closely connected with communication between the hippocampus and the cortex, two brain regions involved in memory formation.

Researchers believe these bursts help the brain protect sleep from outside disturbances while also strengthening memories formed earlier in the day.

Stage 3: Deep Sleep And Physical Recovery

NREM Stage 3, often called deep sleep or slow wave sleep, is the most restorative stage. In this stage, the brain produces very slow electrical patterns called delta waves. These waves indicate that the brain is in its deepest resting state.

Deep sleep is when the body carries out important repair work. Growth hormone is released, muscles recover from physical activity and the immune system strengthens. According to Mark Wu, a sleep expert and neurologist at Johns Hopkins Medicine, this stage is also strongly linked to the restoration of energy and overall physical recovery.

It is difficult to wake someone during deep sleep. If they are awakened, they may feel disoriented or extremely groggy for several minutes.

REM Sleep And Dreaming

Most vivid dreams occur during this stage. At the same time, the body temporarily shuts down most muscle activity, a phenomenon called REM atonia, which prevents people from physically acting out their dreams. REM sleep typically makes up about 25 percent of total sleep time during a normal night.

Researchers have found that REM sleep plays an important role in emotional processing and learning. Multiple neuroscience studies suggest that REM sleep helps regulate emotions and supports the strengthening of neural connections involved in learning new skills.

A recent study reported by Harvard Medical School even found that reduced REM sleep may be associated with an increased risk of dementia later in life, highlighting the importance of this stage for long term brain health.

Why These Stages Matter

Experts in sleep science often emphasize that the quality of sleep matters just as much as the number of hours. When sleep is disrupted, the brain may not spend enough time in the stages that support learning, recovery, and emotional balance.

On World Sleep Day, this growing body of research reminds us that sleep is not wasted time. It is one of the most powerful biological systems the body has for restoring both the brain and the body every single night.

As we observe World Sleep Day today, under the theme “Sleep Well, Live Better”, we find ourselves at a digital crossroads. While we have never been more aware of the benefits of eight hours’ sleep, we have also never been more tempted to sacrifice that, like we are today.

Despite our pursuit of better sleep, modern-day lifestyles with late nights have trapped us in a loop of digital indulgence. The main culprit behind this is the rise of the Over-The-Top (OTT) streaming platforms, which contribute to binge watching, followed closely by constant scrolling on social media. We are sacrificing restorative sleep for the lure of just one more episode, not realizing that the biological toll is higher than we think.

The Allure Of Just One More Episode

Binge-watching is not just a matter of lack of willpower; it is actually a carefully crafted psychological hook. The OTT platforms are designed to ignore our stop signals through features such as auto-play and cliffhanger storylines, which make us want to watch more.

When we decide to watch a particular show at 11:00 PM, we invariably find ourselves glued to the screen even at 2:00 AM, which harms our sleep cycle not only for that day, but also our work performance the next day.

This is actually known as Revenge Bedtime Procrastination, where people who have very little control over their lives during the daytime refuse to go to bed early in a bid to reclaim some freedom during the late hours of the night. However, this is actually an illusion that works to deliberately destroy our circadian rhythm, which in the long term is very harmful to our bodies.

The Biological Backlash

Our bodies operate on a delicate internal clock. When we expose ourselves to the blue light emitted by televisions, laptops, tablets, and smartphones, we suppress the production of melatonin, the hormone responsible for sleep.

Some of the ill-effects of this include:

1. Disrupted Sleep Cycles and Blue Light Blockage

The human brain doesn’t just turn off when we sleep; it cycles through specific stages, moving from light sleep to deep (Non-Rapid Eye Movement) and finally to REM.

Our OTT devices emit high-intensity blue light. This light hits the melanopsin-containing receptors in your retina, which send a direct signal to the Suprachiasmatic Nucleus—the brain’s master clock. This signal suppresses the pineal gland from releasing melatonin.

Melatonin is a natural hormone produced by the pineal gland in response to darkness, signaling the body to sleep and regulating the circadian rhythm.

Depriving yourself of this makes the brain emotionally brittle and unable to distinguish between a minor inconvenience and a genuine crisis the next day.

2. Cognitive Fog: The Failure of the Glymphatic System

Cognitive fog is the subjective feeling of a very real physiological backlog. Think of your brain as a high-performance engine that produces metabolic waste throughout the day. During deep sleep, the space between your neurons increases, allowing Cerebrospinal Fluid (CSF) to rush in and wash away metabolic waste products, such as beta-amyloid (the same protein linked to Alzheimer’s).

Sleep is also when the brain performs synaptic scaling. It weakens unimportant neural connections made during the day so that the important ones (learning and memory) can stand out. When you compromise your sleep cycle for OTT, the trash isn’t picked up.

Your synapses remain cluttered and noisy, leading to slower neural transmission speeds. This manifests as cognitive fog, characterized by problems in focusing and slow-motion thinking.

3. Physical Health Risks: Autonomic Dysregulation

The brain is the command center for your entire body’s physiology. Chronic sleep deprivation caused by late-night digital habits keeps the brain in a state of Hyperarousal. Staying awake late to watch stimulating content triggers the Hypothalamic-Pituitary-Adrenal (HPA) axis. This keeps your cortisol levels (the stress hormone) and norepinephrine abnormally high.

Over time, this chronic fight or flight state leads to structural changes in the brain’s vasculature. The persistent elevation in blood pressure (hypertension) and the metabolic shift toward obesity are direct results of a brain that is being forced to stay awake when it should be recharging.

Beyond OTT, doom-scrolling through social media feeds adds to the mental stimulation. The dopamine hits from the ‘likes’ and short-form videos keep the brain in a high state of arousal, making it nearly impossible to transition into a restful state.

Reclaiming the Night: Practical Solutions

However, to fully live by the motto of “Sleep Well, Live Better”, we need to change the way we think about sleep. Sleep is neither a luxury nor a waste of time; it is the key to efficiency in our tasks during our waking hours.

The solutions are simple, but need discipline:

• Digital Sunset: Just as the sun sets, so too should your digital devices. Try to turn off all OTT platforms and social media at least 60 minutes before bedtime. This will give your body the chance to produce melatonin naturally.

• The One-Episode Rule: If you absolutely have to watch something before going to bed, pick a show that has a definitive endpoint for the night. Turn off the auto-play feature on your streaming services to take back control of your viewing habits.

• Create a Sanctuary: Make the bedroom a screen-free zone. If your phone is your alarm clock, consider purchasing a traditional analog clock to take away the temptation of a quick scroll before drifting off to sleep.
• Mindful Transitioning: Swap out the blue light for low-stimulation activities. Reading a physical book will make your brain think, and you will feel tired after some time, which will lead to better sleep. Some gentle stretching or journaling can help your nervous system understand that the day is over.

Sleep Well, Live Better

This World Sleep Day, let us recognize that no plot twist in a thriller or no viral trend on social media is worth the degradation of our health by compromising on sleep.

The “miracles” we seek—success at work, family time, and personal growth—cannot be built on a foundation of exhaustion. We all need rest so that we can wake up with more energy the next day to achieve our life goals with dedication.

By choosing the pillow over the play button, we aren’t just going to sleep; we are choosing to live a more vibrant, focused, and healthier life.

Jane Fallon, Ricky Gervais’ longtime partner, recently opened up about being diagnosed with breast cancer. The producer of 20 Things To Do Before You’re 30, Fallon explained that her breast cancer was diagnosed during a routine mammogram in December.

“About a month ago I was diagnosed with breast cancer - very early stage thankfully & the prognosis is excellent. I had a routine mammogram a week before Christmas.” She explained that she had no symptoms however; it was her regular check-ups that helped the early diagnosis.

“I had no symptoms, but the brilliant radiographer spotted something iffy & sent me for further tests & eventually a biopsy” With biopsies and an MRI, her healthcare team located the “problem area” and now her surgery has been scheduled for next week.

Why Early Diagnosis Matter For Breast Cancer

According to the Center of Disease Control and Prevention (CDC), breast cancer screening is a proactive checkup used to find cancer before any physical signs or symptoms appear. While screening doesn’t prevent cancer, its goal is early detection, making the disease much easier to treat.

Since every person’s body and history are different, you and your doctor should engage in informed and shared decision-making. This means discussing the pros and cons to decide together if, and when, screening is right for you.

Also Read: Breast Cancer Patients Choosing Alternative Medicine Face Higher Death Risk | Women's Day

The U.S. Preventive Services Task Force (a group of national medical experts) provides guidelines based on the latest research:

Average Risk

Women aged 40 to 74 should generally get a mammogram every two years.

High Risk

If you have a family history or other risk factors, your doctor may recommend a different schedule or additional tests.

How Is Breast Cancer Screening Done?

There are two main imaging tools used to look for breast cancer:

Mammogram

This is a specialized X-ray and remains the "gold standard" for most women. It can spot tumors long before they can be felt, significantly lowering the risk of dying from the disease.

Breast MRI

This uses magnets and radio waves for a detailed image. It is typically reserved for women at high risk and is used alongside a mammogram, rather than instead of one.

Also Read: Breast Cancer To Reach Over 3.5 Mn By 2050, Deaths To Surge 44% Predicts Lancet Study

Breast Cancer Awareness Starts At Home

Staying informed about your body through physical checks is a key part of proactive health. A clinical breast exam involves a healthcare professional using their hands to feel for any unusual lumps or changes in texture.

Parallel to this is breast self-awareness, which encourages you to become familiar with the normal look and feel of your breasts. While neither practice is currently proven to lower the overall risk of death from cancer, they remain vital for identifying immediate concerns like pain or size changes.

Navigating healthcare requires a careful balance of pros and cons, which is why informed and shared decision-making is so important. Every screening test involves a trade-off; while the goal is protection, there is always a possibility of encountering false positives or overdiagnosis.

What Are The Benefits of Early Screening?

The primary advantage of regular breast cancer screening is the ability to achieve early intervention.

When cancer is detected in its earliest stages, often long before a physical lump can be felt, it is typically much smaller and confined to a localized area.

This makes the disease significantly easier to treat and often allows for more successful outcomes with less aggressive medical procedures.

Ultimately, consistent screening provides the best opportunity to find and address issues before they become life-threatening or difficult to manage.