Your Donut Is The Reason Behind Your Depression—Research Shows Shocking Link Between Ultra-Processed Food And Mental Health

Updated May 27, 2025 | 01:00 AM IST

SummaryResearchers have claimed that any improvement in depression is associated with a reduction in microplastic exposure due to dietary substitutions.
Your Donut Is The Reason Behind Your Depression—Research Shows Shocking Link Between Ultra Processed Food And Mental Health

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Your noodles, soft drinks and chips are ruining your mental health. A new viewpoint article published in the journal Brain Medicine highlights a possible role of microplastics in influencing the association between ultra-processed food intake and mental health adversities.

Ultra-processed foods, such as instant noodles, carbonated drinks, and packaged foods, are industrial formulations made from substances derived from whole foods. These food products contain high amounts of industrial additives and involve sophisticated packaging. The consumption of ultra-processed foods is rapidly increasing worldwide, especially in high-income countries. In the United States, these foods are associated with more than 50% of energy intake. Convenience, affordability, accessibility, aggressive marketing, and lifestyle changes are the major factors driving the global dietary shift from whole foods to ultra-processed foods.

Ultra Processed Food Leading To Depression

According to an umbrella review published in The BMJ and referenced in the viewpoint, people who consume ultra-processed foods have a 22% higher risk of depression, a 48% higher risk of anxiety, and a 41% higher risk of poor sleep outcomes compared to those with lower intake.

Recent observational studies indicate that excessive consumption of ultra-processed food is associated with poor sleep quality, physical health adversities, depression, and anxiety. This evidence is further supported by studies reporting that higher consumption of nutrient-rich, unprocessed foods potentially reduces the risk of mental disorders. Small randomized controlled trials, particularly those examining Mediterranean diet interventions in people with depression, have demonstrated moderate-to-large improvements in depressive symptoms. The findings of recent interventional studies also clearly indicate a link between dietary intake and mental health.

Microplastics as a contributing factor

Mental health adversities associated with ultra-processed food intake might be attributed to their poor nutrient profiles, energy density, and physical or chemical properties related to industrial processing and packaging methods, which introduce bisphenols and microplastics as contaminants.

Similar to ultra-processed foods, microplastics are known to induce oxidative stress, inflammation, immune dysfunction, altered metabolism, impaired cell growth and organ development, and carcinogenicity.

Microplastics and nanoplastics can increase the risk of neuropsychiatric disorders by inducing oxidative stress in the brain, causing nerve cell damage, and influencing the functionality of neurotransmitters, such as acetylcholine, γ-aminobutyric acid, and glutamate. However, it is important to note that much of the mechanistic evidence on microplastics and neurological effects comes from animal and cell culture studies, with limited direct human data.

Sources Of Microplastics

Because of processing and packaging methods, ultra-processed foods contain high amounts of microplastics. These foods are often stored and heated in plastic containers, a significant source of microplastics. For example, chicken nuggets can contain 30 times more microplastics per gram than chicken breast, and microwaving some plastic containers may release millions of microplastic and nanoplastic particles within minutes. Besides microplastics, bisphenol A used in plastic production can be released and mixed with ultra-processed foods when plastics degrade. Bisphenol A has been specifically associated with autism and depression in some human studies. These observations clearly indicate that excessive consumption of ultra-processed foods can accumulate microplastics and bisphenol A in the body.

Microplastics in the human brain

Emerging evidence highlights the presence of microplastics in the human brain. These microplastics, mainly polyethylene, are smaller in diameter (less than 200 nanometers) and are 7 to 30 times higher than those found in other organs, such as the liver or kidney. A recent study also found a 50% increase in brain microplastic concentration from 2016 to 2024, paralleling the ongoing rise of ultra-processed foods. One recent study found that people with dementia had three to five times higher levels of brain microplastics, but the authors emphasize this correlation does not imply causation.

Although some human studies have shown a link between bisphenol A exposure and risk of autism, depression, and anxiety, no evidence is currently available linking microplastic exposure to mental health adversities. This gap in knowledge is partly due to the difficulty in quantifying microplastic exposures in the human brain from an observational perspective and the ethical limitations surrounding microplastic exposure in interventional studies.

Implications for dietary intervention

Identifying microplastics in the brain and throughout the body raises significant health concerns. Several studies have highlighted the potential negative impact of microplastics on immune functions, genetic stability, and endocrine functions.

The SMILES trial is the first randomized controlled trial to investigate the efficacy of adjunctive dietary intervention in treating moderate to severe depression. The main aim of the dietary intervention was to replace nutrient-deficient, ultra-processed foods with nutrient-rich, unprocessed foods. The trial findings indicated significant improvement in depression among participants who consumed the intervention diet for 12 weeks. Compared to the 8% control group participants, remission was achieved for 32% of intervention group participants. This means that for approximately every four people who adopted the dietary changes, one additional person experienced remission from depression, compared to the control group (a measure known as the “number needed to treat,” which was 4.1).

Although the trial did not directly measure microplastic accumulation in participants’ bodies, it is imperative to hypothesise that the improvement in depression is associated with a reduction in microplastic exposure due to dietary substitutions. However, this remains a hypothesis requiring further investigation, as microplastic exposure was not directly measured.

The viewpoint notes that it would be valuable to conduct post-hoc analyses in such dietary trials, retrospectively estimating changes in microplastic content due to dietary interventions and their potential effect on mental health outcomes, as more data on microplastic content in foods becomes available.

Need For New Dietary Index

While the paper notes that research quantifying the microplastic content of various ultra-processed food items is becoming increasingly available, it does not state that methods are already well-established for all foods. It would be of prime importance to evaluate the changes in microplastic content due to dietary interventions and their subsequent effect on various mental health outcomes.

Several diet-based risk indices have been developed to assess the long-term impact of dietary exposure on physical and mental health. The Dietary Inflammatory Index has been developed to assess the inflammatory potential of a person’s diet based on the foods they consume. Similarly, the Nova food classification system has been developed to categorise foods based on the extent and purpose of industrial processing.

Given the significant utility of these indices, the authors of this article propose designing a Dietary Microplastic Index to assess the microplastic content and risk of accumulation based on the foods consumed. Currently, no nutritional population-based surveys estimate or track microplastic intake via diet, which precludes robust analysis of long-term microplastic exposure and adverse mental health outcomes. The global rise in the intake of microplastic-enriched ultra-processed foods, together with the simultaneous induction in mental health adversities, highlights the need for more research to investigate this association in humans.

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Harvard Psychologist Lists Careers Linked To Higher Rates Of Suicide: Doctors Maybe At High Risk Themselves

Updated Sep 17, 2025 | 06:52 PM IST

SummaryWe lose more and more people to suicide every year. Being named one of the leading reasons for death, it is a topic that most people shy away from. However, this Harvard doctor says otherwise. In a podcast interview, Dr. Matthew Nock speaks on suicide and people who are at risk for it.

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Suicides are one of the leading causes of death around the world. While it is easy to say that the person who chose to take their lives did it of their own violation, Harvard psychologist Dr. Matthew Nock, explains the other side. “90% of people who try and kill themselves say, I didn't want to die per se. I wanted to escape from seemingly intolerable.” Speaking on the On Purpose podcast with Jay Shetty, Dr. Nock pointed out that the link between work pressure and suicidal thoughts varies by race and ethnicity.

The concerning rise in suicide cases tied to work pressure has fueled a social media conversation about toxic work culture. What was once considered a normal part of the professional grind is now being openly challenged, as people share personal stories of the anxiety, depression, and isolation caused by unhealthy work environments.

What Professions Are At High Risk Of Suicide?

According to Dr. Matthew Nock, certain careers are linked to a higher risk of suicide.

Police Officers

He noted that physicians and police officers are among those at high risk. He mentioned a spike in suicides among New York City police officers, who are predominantly white men, and shared that female police officers, in particular, face a higher risk, even when accounting for factors like age, race, and ethnicity.

According to a 2025 study published in the Police Practice and Research, on average, 21.4 out of every 100,000 officers died by suicide each year.

The study showed that the suicide rate was much higher for male officers (22.7 per 100,000) than for female officers (12.7 per 100,000).

Physicians

Dr. Nock explained that access to means is a significant factor in these high-risk professions, which helps explain why physicians, police officers, and military members have a much higher risk of suicide compared to others.

Another study published in 2024 The BMJ, showed that the number of suicides among doctors has been going down, female doctors are still at a much higher risk than other people.

When looking at all the data, male doctors were found to have a 5% higher risk of suicide compared to the general population.

In a more recent analysis of the last few years, the overall suicide rate for doctors has decreased, which is good news. But even with this improvement, female doctors still have a 24% higher risk than the general public.

Why We Need To Talk More About Suicide

Dr. Nock stresses the importance of openly discussing suicide, particularly in schools. He compared it to fire drills or earthquake preparedness, saying that since 15% of people will experience suicidal thoughts, it's crucial to equip everyone with a safety plan..Dr. Matthew Nock said, "We know that asking about suicide, talking about suicide, does not make people suicidal."

He noted that the people who act on suicidal thoughts often show different signs than those who just have the thoughts. While depression is a strong predictor of having suicidal thoughts, other factors like anxiety, aggressiveness, poor behavioral control, and drug or alcohol use are more closely linked to a person actually attempting suicide.

He believes that a small educational module on suicide in health class could help save lives by teaching people what to do if they or someone they know is struggling.

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'You’ve Been Pooping Wrong All Your Life' According To Harvard Gut Doctor, 3 Mistakes That Harm Your Health

Updated Sep 17, 2025 | 07:00 PM IST

SummaryUsing the washroom to relieve yourself and move your bowels is one of the easiest activity that keeps our gut healthy. But do you know how your poop can affect your health as well? This gut doctor revealed that making these mistakes when you are pooping could change your health all together?
'You’ve Been Pooping Wrong All Your Life' According To Harvard Gut Doctor, 3 Mistakes That Harm Your Health

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Maintaining our gut health is not as easy as it seems. Even things like how you do your bowel movements could reveal how healthy your gut actually is. According to Dr. Saurabh Sethi, a board-certified gastroenterologist, many of us are making common mistakes on the toilet that can lead to real health problems. Here are three crucial habits to change to improve your gut health. Here are three mistakes' people make will they are in the washroom.

3 Bathroom Mistakes You Are Making

Stop Straining

Pushing or straining when you poop can cause serious issues like hemorrhoids, which are swollen veins in your rectum and anus, and anal fissures, which are small tears in the lining of your anus. In more severe cases, it can even lead to rectal prolapse, where part of the rectum slides out of the anus. Instead of forcing it, focus on taking deep breaths. This helps your abdominal muscles relax and allows your body to do its job naturally, reducing the risk of painful complications.

Put Down Your Phone

Scrolling on your phone while on the toilet can be a bad habit. Spending extra time on the toilet, even if you’re not straining, puts pressure on the delicate veins in your rectum. This can cause them to swell, significantly increasing your risk of hemorrhoids. To protect yourself, it’s best to keep your bathroom breaks short—ideally, under five minutes.

Don't Ignore the Urge

When you feel the need to poop, it's important not to hold it in, which makes it much more difficult to pass later, leading to and worsening constipation. When you feel the need to go, listen to your body. Holding it in causes your stool to get harder and drier, which makes constipation much worse and more painful later on. Train your gut to go when it says it's time.

Simple Ways To Improve Your Bowel Movements

Go at the Same Time Each Day

Try to create a routine. If you're often straining without success, try sitting on the toilet about 30-60 minutes after a meal, when your colon is naturally more active. A little stretching or a short walk beforehand can also help things get moving.

Use a Stool for Your Feet

The natural position for a bowel movement is squatting. You can mimic this position on a regular toilet by placing a small stool under your feet to raise your knees above your hips. This simple change helps your muscles relax and can make bowel movements easier and more complete.

Focus on Fiber and Fluids

Fiber is essential for creating soft stool that's easy to pass. Most adults should aim for 25 to 35 grams a day. Just remember to add it to your diet slowly. As you increase your fiber, be sure to drink more water and other non-caffeinated fluids, since caffeine can dehydrate you and make stool harder.

When to Seek Help

While these tips are a great starting point, sometimes you need more personalized help. You should talk to your doctor if you notice any of these signs:

  • A recent, unexplained change in your bowel habits
  • Blood in your stool
  • Unexplained stomach pain
  • A pelvic health physical therapist can also provide a full evaluation and create a personalized plan to improve your bowel health.

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Does Owning Pets Increase Your Risk of Lyme Disease? Expert Reveal The Truth

Updated Sep 17, 2025 | 10:00 PM IST

SummaryLyme Disease is a growing concern, a disease that affects thousands of people each. Even though you may keep clean, and follow a proper hygiene routine, you may be at risk if you have pets? But how can pets increase the risk factor, can it be avoided? Here is what you need to know.
Does Owning Pets Increase Your Risk of Lyme Disease? Expert Reveal The Truth

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In recent news, you may have heard of new cases of Lyme disease popping up, a general increase in number has been noted. A few months ago, celebrity Justin Timberlake also shared his Lyme disease diagnosis, sparking a conversation regarding this disease. Many people have questions regarding the same, is it fatal, what kind of treatment do you need for it etc.

A major concern lies with pet parents, could their pets be carrying the bugs and does it affect them as well?

One of the first things you should know is that Lyme Disease is a zoonotic disease. These are illnesses that spread from animals to people. According to Lyme Disease organization, you might be surprised to learn that over 60% of all diseases that make us sick come from animals. Knowing how they get passed on is the first step to staying healthy. To understand its risks and early symptoms, we spoke to Dr. Karan Malhotra, a consultant dermatologist at CMRI, Kolkata.

How Does Lyme Disease Spread?

Zoonotic diseases can spread in a few different ways. The most direct way is through animal-to-human contact, which can be as simple as an infected animal biting you, like with rabies.

In the U.S., the most common one is Lyme disease, which a tick can pass on after it feeds on an infected animal. Ticks are actually responsible for 94% of all vector-borne diseases in the country, and mosquitoes infect millions of people around the world each year with diseases like malaria.

Are Pet Parents At Higher Risk for Lyme Disease?

A major concern for pet owners is whether their pets can bring ticks and the disease into their homes.

"Yes, that's true," says Dr. Malhotra, "Being a pet parent, especially with cats and dogs, increases your probability of encountering ticks and potentially getting Lyme disease, as pets can bring them into the home and introduce them to household members."

Because of this, pet-owning households are nearly twice as likely to have ticks in their homes and 1.5 times more likely to find ticks on family members compared to homes without pets.

Are There Signs That Your Pet Is Carrying Lyme Disease?

"Yes, absolutely. Pets can also be affected by Lyme disease," confirms Dr. Malhotra. Lyme disease is caused by a type of bacteria called Borrelia burgdorferi, which is carried by infected black-legged (deer) ticks. When a tick latches onto your pet for more than 24 hours, the bacteria can get into their bloodstream and spread throughout the body, leading to serious health problems. Some pets may not show any signs, but common symptoms to watch out for include:

  • Lethargy and fatigue: Your pet seems unusually tired or less active.
  • Fever
  • Loss of appetite.
  • Shifting lameness: Your pet's limp seems to move from one leg to another.

What Happens When Lyme Disease Is Left Untreated?

If left untreated in both humans and pets, Lyme disease can lead to serious complications. "Untreated Lyme disease can lead to significant complications affecting the joints, heart, and nervous system," explains Dr. Malhotra. These complications can include:

Lyme Arthritis: Joint pain and swelling.

Cardiac issues: Heart block and a slow heart rate.

Neurological problems: Facial paralysis, nerve damage, and cognitive difficulties like brain fog.

The bacteria can spread from the initial bite to other organs and tissues, causing these widespread issues if not treated promptly.

Simple Ways to Stay Safe

Preventing these diseases is all about avoiding exposure. If you live or work in an environment where you are around animals, here are a few simple steps you can take to protect yourself:

  • Practice good hygiene. Always wash your hands and surfaces after touching animals or handling raw food.
  • Drink safe water.
  • Protect yourself and your pets from insects. Use tick and insect repellent, and make sure your pets are on year-round flea and tick medication.
  • Keep your pets healthy with regular vet visits and vaccinations.
  • Get vaccinated yourself for any preventable illnesses when possible.

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