Probiotic supplements promise a healthier gut, but what happens if it become deadly? In a stunning Japanese case, a man's everyday probiotic set off a deadly bloodstream infection. The unusual but disturbing event has raised urgent questions about the safety of probiotics, particularly for people with underlying health issues. Is your gut-friendly supplement a silent danger?

In a rare and unexpected case, a 70-year-old Japanese man developed a deadly bloodstream infection attributed to the very probiotic supplements intended to enhance his health. His case, which was reported in BMJ Case Reports, has sparked serious questions regarding the possible dangers of probiotics, especially for those with weakened health.

The man, who had a history of alcohol dependence and underlying medical conditions, was found collapsed in his home and was rushed to the hospital. Upon examination, doctors diagnosed him with metabolic acidosis—a dangerous buildup of acid in the blood—triggered by a severe lung infection, kidney injury, and possibly heavy alcohol use.

To his list of health issues, the patient tested positive for COVID-19. He was put in the ICU, where he was provided with intensive care, such as breathing assistance, a blood thinner, anti-inflammatory steroids, and tocilizumab—a medication used to suppress inflammatory proteins. In addition to treating a secondary bacterial infection, he was administered antibiotics, which caused diarrhea, a typical side effect.

In an attempt to get his gut health back, doctors prescriped a probiotic with Clostridium butyricum, a naturally occurring bacterium in approximately 20% of healthy people. Although considered safe, the probiotic unexpectedly and fatally turned in his instance.

For nearly two months, the patient appeared to be recovering. However, he suddenly developed severe fatigue, swelling, and persistent abdominal pain. Body scans revealed a life-threatening reduction in blood flow to his intestines—a condition that often results in tissue death and organ failure.

As his health worsened, blood work was done, and an alarming finding was discovered: C. butyricum bacteria were found in his blood. This was a definite indication of probiotic-associated bacteremia—a rare but reported side effect in which bacteria from a probiotic supplement get into the bloodstream and infect the body. Genetic testing proved that the strain in his blood was the same as the one in the probiotic he had been consuming.

In spite of medical treatment, the patient's condition deteriorated quickly. His immune system, already compromised by his medical history of colon cancer, high blood pressure, heart disease, and smoking, could not combat the infection. Because of his unstable status, surgical intervention was not possible. In a matter of days, he had multiorgan failure. With no other medical options available, physicians switched him to palliative care, and he sadly died on the 60th day of hospitalization.

How Might a Probiotic Supplement Become Lethal?

Probiotics are frequently utilized to maintain gut health, particularly following antibiotic use. Probiotics replace beneficial bacteria, enhance digestion, and alleviate inflammation. In rare instances, however, probiotics may break through the gut and enter the blood, causing severe infections. This is more likely in people with compromised immune systems, chronic disease, or underlying gastrointestinal disease.

A number of studies, one of which was released in 2019, have established genetic associations between probiotics and hospital patient bloodstream infections. This case contributes to mounting evidence that while probiotics are generally good for many people, they can be dangerous for susceptible populations.

Who Is Most at Risk?

Though probiotic infections are unusual, some groups are at greater risk, which includes:

• Older patients with multiple comorbidities: As in this case, older patients with comorbidities are at increased risk of developing serious complications.
• Patients with compromised immune systems: Diseases like cancer, chronic kidney disease, and autoimmune diseases raise the risk of infection.
• Critically ill or hospitalized patients: The combination of several treatments, including steroids and immunosuppressive medications, can further increase the risk.

Individuals with gastrointestinal abnormalities: An existing gut problem makes it simpler for probiotics to cross the intestinal barrier and get absorbed into the blood.

Should You Stop Eating Probiotic Supplements?

Even with this unfortunate case, health specialists highlight that probiotics are still safe for most healthy individuals. Nevertheless, they advise using probiotics cautiously, especially in high-risk patients.

Experts point out that although probiotics are prescribed to patients suffering from gastrointestinal conditions, rare but serious side effects can take place. He emphasizes that healthcare practitioners should screen a patient's history before they suggest probiotics, particularly in a hospital setting.

Probiotics are commonly lauded for their shield against colds, digestive problems, and severe health ailments. Their advantages are still controversial, though. A new study conducted by UC San Francisco researchers contradicts the notion that probiotics, in particular the Lactobacillus strain, ward off eczema—a disease commonly associated with asthma.

Probiotics, which exist in supplements and foods that are fermented such as yogurt and kefir, are believed to help promote the health of the gut by enhancing immune function and suppressing disease-causing pathogens. According to the World Health Organization, they are "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host."

Released in Pediatrics on August 7, 2017, the research surveyed high-risk asthma infants. Comparing those supplemented with probiotics for six months to those that were not supplemented, researchers saw no apparent effect that probiotic supplementation has in lowering the risk of eczema, fueling the continued controversy surrounding their actual health effects.

It started with a simple TikTok video, four large carrots shaved into ribbons, mixed with garlic, sesame oil, lime juice, coconut aminos, rice vinegar, and green onions. The resulting “crunchy and addictive” salad quickly racked up millions of views under the viral trend #EatYourRetinol. But is it just social media hype, or can what’s on your plate really show up on your face?

The trend encourages eating vitamin A-rich foods, like carrots, to support skin health from the inside out. “Skincare always starts within,” says Johanna Salazar, registered dietitian nutritionist and founder of Healing Nutrition, as noted by Martha Stewart. But experts urge a balanced view: while diet can support your skin, it’s not a magic replacement for topical care.

What’s in the Carrot Salad That’s Good for Your Skin?

The base of the salad, carrots, are packed with beta-carotene, a precursor to vitamin A, known for boosting skin cell turnover and promoting a radiant complexion. Pairing it with a fat, like sesame oil, helps your body absorb the fat-soluble vitamin. Lime juice adds vitamin C, key for collagen production, while garlic and green onion offer prebiotics that support gut health, which in turn impacts skin health.

Sesame seeds sprinkled on top bring in vitamin E and fiber, which contribute to skin hydration and a healthy glow.

“It’s a nice mix of ingredients that all play small but beneficial roles in skin support,” says Salazar.

Dermatologists Weigh In: Not a Cure-All

Lauren Kole, M.D., associate professor of dermatology at the University of Alabama at Birmingham, appreciates the effort to eat for skin health—but with a word of caution.

“Deficiencies in certain vitamins and minerals can negatively affect the hair, skin, and nails,” she says. “But eating an excess doesn’t necessarily make your skin better.”

Kole points out that while beta-carotene from carrots is helpful, it's not strong enough to replace prescription retinol or other topical treatments for conditions like acne or hyperpigmentation. “Diet is not a substitute for proper skin care,” she emphasizes.

Beyond Carrots: Other Skin-Loving Foods

Experts agree that eating for your skin isn’t just about one salad. A variety of fruits, vegetables, and healthy fats are essential. Salazar and Kole both recommend incorporating:

Dark-colored fruits like berries and red grapes, which are high in antioxidants that fight oxidative skin damage.

Leafy greens such as spinach, kale, and chard, which are rich in vitamin C and help with collagen production.

Vegetables like broccoli, mushrooms, and cauliflower, which support healthy pigmentation and skin repair.

Healthy fats including avocados, walnuts, flaxseeds, and omega-3-rich foods to reduce inflammation and maintain skin moisture.

According to Kole, diets like the Mediterranean diet—rich in plant-based foods and good fats, have shown potential skin benefits in clinical settings.

Don’t Ditch Your Skincare Just Yet

While the “Eat Your Retinol” movement has its heart in the right place, Salazar and Kole stress that no food trend should replace professional skincare or personalized advice.

Lizzy Davis, Ph.D., a dietitian and assistant professor at UAB, advises people to approach such trends with balance.

“Cooking carrots, for example, doesn’t reduce their skin-friendly fiber,” she notes. “It can actually make them easier to digest and still beneficial.”

Davis also warns against over-relying on TikTok or Instagram for skincare advice. “Talk to your doctor or a registered dietitian,” she says. “Social media is convenient, but it can’t give you a plan tailored to your needs.”

We already know that ultraprocessed foods are linked to obesity, heart disease, and diabetes. But now, a new study published in the medical journal Thorax suggests a concerning addition to that list, lung cancer.

According to researchers, people who consume the highest amounts of ultraprocessed foods may face a 41% higher risk of being diagnosed with lung cancer, compared to those who eat the least, even when accounting for smoking and other known risk factors.

What Are Ultraprocessed Foods?

Ultraprocessed foods are industrial formulations made largely or entirely from substances not typically used in home cooking.

According to the Food and Agriculture Organization of the United Nations, these include artificial colorings, preservatives, emulsifiers, and chemically altered fats, sugars, or salts.

Common examples? Think sodas, chips, packaged soups, processed meats like chicken nuggets and cold cuts, instant noodles, diet soft drinks, and even some ice creams.

These additives enhance taste, shelf-life, and appearance, but at what cost?

What Does The Study Reveal About Food Choices and Lung Cancer Risk

Researchers behind the Thorax study analyzed data from over 100,000 adults who participated in the U.S. National Health and Nutrition Examination Survey. Each person filled out a detailed dietary questionnaire, which researchers then compared with medical records to track lung cancer diagnoses over time.

On average, people reported eating nearly three servings of ultraprocessed food a day, most commonly lunch meats and soft drinks.

Despite adjusting for smoking habits, age, sex, and other lifestyle factors, the study found a clear association between higher ultraprocessed food intake and increased lung cancer risk, particularly among people who had never smoked.

“This strongly suggests that these foods may contribute to lung cancer risk in ways beyond just smoking,” said Dr. David Katz, a specialist in preventive and lifestyle medicine and founder of the nonprofit True Health Initiative, as reported by CNN. Though not involved in the study, Katz called the findings “concerning and credible.”

Why Would Food Be Linked to Lung Cancer?

Experts believe multiple mechanisms could be behind the link.

“Industrial processing alters the food matrix,” the study authors explained, “which affects how nutrients are absorbed and may produce harmful contaminants.”

One such contaminant is acrolein. It is a toxic compound found not only in cigarette smoke, but also produced when cooking oils or fats are heated to high temperatures.

The U.S. Centers for Disease Control and Prevention (CDC) lists acrolein as a substance that can inflame and damage lung tissue.

Packaging may also be a problem. Plastics and synthetic materials used in food storage can leach chemicals, some of which are known or suspected carcinogens.

Add to that the fact that ultraprocessed foods are often low in omega-3 fatty acids, said Dr. Tom Brenna, professor of nutrition and chemistry at the University of Texas at Austin, as reported by CNN.

“Omega-3s spoil easily, so manufacturers tend to remove them to increase shelf life,” he explained. That’s unfortunate, because omega-3s help reduce inflammation, a key process in cancer development.

Smoking Isn’t the Only Risk Factor

Lung cancer remains one of the most commonly diagnosed cancers globally, with 2.4 million new cases in 2022, according to the World Health Organization. While smoking remains the leading risk factor, experts now believe diet and environmental exposures also play a role.

Dr. Fang Fang Zhang, a professor at Tufts University’s Friedman School of Nutrition Science and Policy, as reported by CNN, noted that while the study adjusted for smoking, the adjustment may not have been thorough enough. “Smoking needs to be measured more precisely, by cigarettes per day or years of exposure,” she said. Still, she found the link stronger in non-smokers, which makes the data all the more compelling.

What You Can Do: Eat More Whole Foods

The takeaway? While more research is needed to understand the exact biological mechanisms at play, the connection between ultraprocessed foods and cancer risk can no longer be ignored.

According to Dr. Katz, the solution lies in going back to basics. “Health and diet quality improve when people eat mostly whole, unprocessed foods,” he said, including vegetables, fruits, beans, whole grains, nuts, seeds, and other plant-based ingredients.

Dr. Zhang agrees. “Avoid foods with long ingredient lists full of unfamiliar chemicals,” she advised. “Focus on meals made from whole or minimally processed ingredients whenever possible.”

Fish oil is a star supplement loaded with omega-3 fatty acids like EPA and DHA. It offers a spectrum of vital benefits for women’s health. These extend beyond general well-being to support heart, brain and joint function, especially in areas of concern specific to women.

Fish oil, rich in omega-3s, addresses unique needs across all stages of a woman’s life. From adolescence through motherhood to menopause, fish oil supports cardiovascular, hormonal, mental and reproductive health.

A Boost for the Heart

Fish oil plays a major role in promoting heart health. According to Dr Mohit Bhatia, it helps lower triglyceride levels, a risk factor for cardiovascular disease, and improves blood flow, making it essential for proper cardiovascular function. He adds that it also slows the progression of cardiovascular disease.

Karan Khurana, a health expert at WishNew Wellness, concurs, saying that omega-3s in fish oil reduce triglycerides, lower blood pressure, and decrease arterial inflammation. This is particularly vital for post-menopausal women, who face a greater risk of heart disease. Regular consumption of fish oil, he says, can even lower the risk of heart attacks and strokes.

Hormones, Menstrual Cycles and PMS

Women facing bloating, mood swings or cramps may find some relief with fish oil. Dr Bhatia says that some evidence-based research suggests fish oil can help alleviate PMS and menstrual pain, thanks to its anti-inflammatory properties.

Khurana elaborates that omega-3s may regulate menstrual cycles and reduce cramps by lowering prostaglandin levels, which contribute to pain and inflammation. He adds that fish oil can ease common PMS symptoms such as bloating and breast tenderness.

Pregnancy, Postpartum and a Baby’s Brain

The benefits of fish oil carry into pregnancy too. Dr Bhatia points out the importance of DHA during this stage, saying it is vital for healthy foetal brain and eye development. It may also reduce the risk of preterm birth and help alleviate postpartum depression.

Khurana backs this up, pointing out that fish oil supplementation not only supports cognitive function in babies but also helps mothers manage postpartum depression. It plays a role in maintaining the mother’s brain health during and after pregnancy.

Bones, Joints and the Menopause Years

Post-menopause, bone health becomes a serious concern for many women. Dr Bhatia says that the anti-inflammatory properties of fish oil can contribute to bone health, potentially reducing the risk of osteoporosis.

Khurana adds that omega-3s enhance calcium absorption and support bone density. Fish oil, he explains, helps reduce inflammation linked to joint pain, promoting stronger bones and better mobility for older women.

Better Moods and Sharper Minds

Women are more likely than men to experience anxiety and depression, and fish oil might just help. Dr Bhatia explains that these fatty acids play a role in elevating mood and supporting brain function, potentially mitigating cognitive decline.

Khurana agrees, saying omega-3s support cognitive health and reduce the risk of dementia later in life. Fish oil, he says, may alleviate symptoms of depression and anxiety, contributing to overall mental well-being.

Your Skin Will Thank You Too

Dr Bhatia does not touch on it, but Khurana dives into skin benefits. He says that fish oil improves hydration, reduces wrinkles, and protects against UV damage. Its anti-inflammatory effects can ease conditions like eczema, making skin look and feel healthier.

Final Thoughts Before You Pop That Capsule

Dr Bhatia emphasises that while fish oil is a powerful supplement, it should complement a balanced diet and healthy lifestyle. He strongly recommends consulting a healthcare professional before starting, especially for those on medication or with existing conditions.

Khurana suggests aiming for 250–500 mg of combined EPA and DHA daily, either through fatty fish like salmon or through supplements. Fish oil, he concludes, is a holistic powerhouse that can help women thrive at every stage of life.