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We all have learned how the maternal experiences and struggles during pregnancy profoundly influence the unborn child. From nutritional deficiency to emotional stress, every choice and challenge shapes baby development. These invisible connections between biology and love remind us how the mother's journey is deep-rooted in relation to the lifelong health of her offspring.
Newborn health has been the focus of research in medicine and science for quite some time now, as the early years of life usually lay the groundwork for long-term health. New research has begun to reveal just how maternal factors, such as the effects of the X chromosome and vitamin D levels during pregnancy, shape the health trajectory of a newborn. These findings unravel the intricate interplay between genetics, epigenetics, and maternal contributions in brain health and development, bringing new insights into how we approach neonatal care.
The maternal X chromosome, teeming with genetic material, plays a pivotal role, perhaps impairing memory and cognitive abilities over time. Recent research indicates a significant correlation between the DNA of a mother and her baby's brain health and aging process. Studies on mice indicate that maternal genes may accelerate biological aging in the hippocampus—a brain region crucial for learning.
Moreover, silenced genes on the maternal X chromosome may have keys to cognitive development. When combined with health factors related to the mother, such as the vitamin D level during pregnancy, this complex genetic dance underscores how a mother's DNA profoundly shapes the lifelong health trajectory of her baby. An interesting study has found that the X chromosome inherited from the mother could hasten brain aging in offspring, thus increasing the susceptibility of diseases such as Alzheimer's.
Though women have two X chromosomes and men have one X and one Y, the genetic material of the X chromosome is very important. Mutations or changes in this chromosome can greatly affect brain health.
Researchers have found that in females, one X chromosome is randomly inactivated in each cell, a phenomenon that may explain some of the individual differences in brain health outcomes. Although women typically live longer and have a lower overall dementia rate than their male counterparts, Alzheimer's disease disproportionately affects females, often raising questions about the underlying genetic mechanism.
Dena Dubal and Abdulai-Saiku led research into the impact of maternal X chromosomes on brain health. They found that female mice with an active maternal X chromosome showed accelerated biological aging in the hippocampus, a region of the brain important for learning and memory. These mice also showed worse cognitive abilities as they aged compared to those with contributions from both maternal and paternal X chromosomes.
Interestingly, the cognitive abilities of aged female mice improved when researchers used CRISPR gene-editing technology to activate silenced genes on the maternal X chromosome. This finding underscores the importance of the genetic expression of the maternal X chromosome in influencing brain health.
It thus provokes the mind with such a question, where maternal genetic contribution is actually found shaping brain development and aging in human. Should similar mechanisms prevail, targeted therapies may prevent the decline that typically accompanies the passing of age to improve general health of the brain.
Another dimension of maternal influence over the health of newborns is vitamin D level in pregnancy. Deficiency of vitamin D has been one of the most common problems, especially among pregnant women in Asia. Several adverse health conditions have also been correlated with vitamin D deficiency.
Vitamin D's influence extends beyond its well-known role in bone health. Emerging evidence highlights its epigenetic effects, such as programming fetal development and shaping immune cell function. One critical epigenetic mechanism is DNA methylation, which predicts biological age and reflects developmental processes.
A Japanese study published in Nutrients looked into the impact of maternal vitamin D on epigenetic gestational age acceleration-a biomarker for neonatal and adult health. The results found that vitamin D deficiency during pregnancy may affect the development of a fetus, placing newborns at risk for infections, obesity, and other health-related issues later in life.
Given the high prevalence of vitamin D deficiency, these findings highlight the importance of intensive prenatal care, including monitoring and supplementation of maternal vitamin D levels. Correction of this deficiency may have a significant role in improving neonatal outcomes and laying the foundation for healthier adulthood.
Also Read: Is Father Equally Responsible For Baby's Health?
X chromosomes have long been recognized as critical to brain health. Previous research has linked mutations in the X chromosome to intellectual disabilities and cognitive impairments. For instance, women with Turner Syndrome, who have only one X chromosome, often experience cognitive challenges.
This genetic influence might also explain differences in cognitive abilities, verbal memory, and susceptibility to brain disorders between sexes. The maternal X chromosome, as highlighted in recent studies, appears to be particularly influential in shaping these outcomes.
The intricate relationship between maternal factors and newborn health underscores the importance of a comprehensive approach to prenatal care. Key takeaways include:
Genetic Contributions
Maternal genes, especially the X chromosome, may therefore play a large role in cognitive health and aging.
Nutritional Interventions
Fixing maternal deficiency in vitamin D may mitigate potential risks associated with developmental and long-term health concerns.
Future Research
Further research on the contribution of mothers to their health, furthered by the development of newer technologies such as CRISPR, promises to bring significant advancements in neonatal and adult healthcare.
Understanding the profound implications of maternal health on newborns changes the focus of neonatal care. From genetic effects to the significance of nutrients, such as vitamin D, research emphasizes the demand for an all-inclusive approach that is more science-based about maternal and neonatal health. As researchers explore the links of maternal factors in long-term wellbeing, healthcare facilities around the globe must evolve towards better support systems, education programs, and intervention strategies for would-be mothers.
This developing field of research reminds us that the journey to a healthy life begins long before birth, in the intricate bond between mother and child.
The maternal X chromosome affects cognition and brain ageing in female mice. Nature (2025)
(Credit-Canva)
While parents often claim they do not have a favorite child, sometimes their favor is evident. Sometimes it is the kid they depend on the most, other times it is the youngest kid of the family. However, is there a specific factor parents enjoy more in their kids? After analyzing factors like age, gender and behavioral pattern, researchers found what parents favored the most in their children
In a 2025 study published by the Psychological Bulletin, researchers found that parents favor daughters. They are more likely to be the favorite, across both mothers and fathers. Firstborn children also often receive more positive attention. Additionally, children who are described as conscientious – meaning they are responsible, organized, and do what they're supposed to – are also frequently favored. These findings suggest that certain personality traits and birth order can influence how parents interact with their children, even if unintentionally.
Researchers looked at the results of many different studies. They combined the findings from over two dozen research papers, including articles, school projects, and large collections of data. This allowed them to see broader patterns in how parents treat their children differently. By looking at things like how much affection parents show and how they share resources, the researchers could draw more reliable conclusions than if they had just looked at one single study. This big picture approach helps us understand the common trends in parental favoritism.
Parents tend to grant older children more freedom and decision-making power, likely due to perceiving them as more mature and responsible based on their age and experience. Having navigated earlier developmental stages, they've often earned more trust, leading parents to offer greater independence compared to their younger siblings who are still learning and growing.
Social norms and potential emotional closeness might contribute to daughters being favored. Parents may have different communication styles or expectations, possibly leading to a stronger perceived bond. While conscientiousness and agreeableness play a role overall, a general inclination towards daughters could also stem from subtle societal influences on parental perceptions and interactions.
Children who are responsible, organized, cooperative, and kind often experience more positive parental interactions. Their agreeable nature leads to less conflict, creating smoother relationships. These traits can make parenting easier, resulting in more praise, trust, and overall favored treatment compared to siblings who may exhibit more challenging behaviors.
When children feel like they are not the favorite, it can have a real impact on their well-being. It's not just about feeling a little sad; it can affect their mental health, their relationships with others, and even how well they do in school. To make sure all their children feel equally loved and valued, parents can try a few practical things.
It's helpful for parents to regularly think about how they interact with each child. Showing interest in each child's unique hobbies and asking them open-ended questions about what's important to them can make a big difference.
Spending dedicated one-on-one time with each child and avoiding comparisons between them are also key. Encouraging a positive relationship between siblings and openly talking about everyone's needs can create a more supportive and equitable family environment.
Credits: Canva
Trying to conceive in your 30s can feel like a race against time, but what if the secret to increasing your fertility was as easy as taking a walk outside for some sunlight? Yes, you heard that right! New studies indicate moderate sun exposure to have a crucial role in maintaining ovarian health and fertility, particularly for women past the age of 30. The quest for fertility and reproductive well-being assumes greater importance with advancing age for women, more so after passing the 30s. That biological functions change with age for women is not a secret, and with this comes the dip in fertility as well but what if something as easy as sunlight could improve those chances? Research indicates that moderate sunlight exposure may play a big role in ovarian health and fertility, particularly in women aged over 30.
We've known for years that sunlight improves our mood and mental health. Natural serotonin production while being exposed to sunlight is well-documented, but new studies are now connecting sunlight exposure with better fertility rates, especially among women aged over 30.
A study appearing in Steroids, authored by scientists at Tel Aviv University and the Sheba Medical Center, reveals how solar radiation exposure may impact fertility. The study, in particular, examined how sun exposure influenced the level of Anti-Müllerian Hormone (AMH) in women. AMH is an important marker of ovarian reserve—the amount of eggs a woman possesses in her ovaries, which determines her fertility potential.
The scientists followed 2,235 women aged 20 to 40 and discovered an interesting trend: women aged 30 to 40 who were exposed to moderate amounts of sunlight in spring and autumn had more AMH compared to those exposed to little sunlight in winter months. Surprisingly, those who were exposed to more solar radiation in summer had greater levels of AMH than those in the winter. Although the study does not create a direct cause-and-effect relationship, it does imply that moderate sun exposure can be good for ovarian reserve and therefore fertility.
Vitamin D, or the "sunshine vitamin," is manufactured by our skin after exposure to sunlight. Vitamin D has been found to be very important for fertility, especially for women who are attempting to get pregnant. A deficiency in vitamin D has been linked to unfavorable fertility outcomes, such as lower IVF success rates and an increased risk of pregnancy complications.
For women attempting conception without medical aid, having optimal levels of vitamin D can maximize the possibility of conception. A number of studies establish that women with higher levels of vitamin D are likely to have better rates of implantation of the embryo and better success when undergoing IVF treatment. The relationship between vitamin D and fertility highlights the need to maximize exposure to sunlight or take supplements, especially for those attempting conception.
While moderate sun exposure will improve fertility by increasing vitamin D levels and AMH levels, it's necessary to counterbalance this with the danger of too much sun. Long-term exposure to strong sunlight can cause sun damage, premature aging, and increased skin cancer risk. So, it's worth striving for safe, moderate sun exposure—usually, about 10 to 30 minutes a few times a week, depending on the type of your skin and sun intensity.
It's essential to pay attention to your body and not expose yourself to the sun during the strongest hours, usually between 10 a.m. and 4 p.m. Applying sunscreen to longer exposures and dressing in protective clothing is worth considering to avoid long-term damage to your skin.
Sunlight exposure is only half the solution when it comes to enhancing fertility among women aged 30 and above. Embracing a healthy lifestyle can also contribute in a notable way to enhancing reproductive health. These are some of the most important lifestyle changes that can enhance fertility:
A healthy diet high in antioxidants, healthy fats, and whole foods may also contribute to improving fertility. Foods that are rich in nutrients such as folic acid, zinc, and omega-3 fatty acids play a critical role in maintaining reproductive health. Especially, consuming fruits, vegetables, lean protein, and whole grains can normalize hormones and make conception more likely.
Physical exercise is essential for general health and fertility. Regular, moderate exercise—like walking, swimming, or yoga—can help normalize hormones, enhance blood flow, and alleviate stress. Excessive exercise, on the other hand, can have the opposite effect and harm fertility. Women who overexert themselves or have extremely low body weight can suffer from menstrual irregularities, which can prevent ovulation.
Chronic stress is a proven fertility killer, as it can cause hormonal imbalance and affect ovulation. Adding stress-reduction methods like yoga, meditation, or breathing exercises can help balance your body. Also, talking to a counselor or therapist can be helpful in resolving emotional and psychological stress that could be impacting your fertility.
Sleep is necessary for hormone balance and overall health. Lack of sleep can raise cortisol levels and interfere with your reproductive hormones. Get 7 to 9 hours of quality sleep each night to aid your fertility and overall health.
Although no one factor can promise fertility, sunlight exposure may be a natural and inexpensive means of aiding reproductive health. Along with a healthy diet, exercise on a regular basis, and stress management techniques, you can really boost your chances of conception, particularly if you're in your 30s. Fertility is a multifaceted process, and it's always a good idea to consult with a healthcare provider when changing your lifestyle or embarking on a family planning adventure.
Moderate sunlight exposure not only does your mood and mental health good but also has an unsuspected but possibly vital role to play in enhancing ovarian health and fertility beyond the age of 30.
Credits: Canva
The US is facing a long-term decline in the birth rates. As per experts, this raises a concern in terms of what this means for country's future, especially with regard to health of its population, economy, and caregiving systems.
As per the new data released by the US Centers for Disease Control and Prevention (CDC), more than 3.6 million babies were born in 2024. This is just a 1% increase from the previous year, which had been the lowest record in births. While this uptick may seem encouraging, it is not enough to reverse the troubling trend.
The US fertility rate remains around 1.6 births per woman. This is significantly below the 2.1 births that is required to sustain the population growth without immigration.
As per the demographers, this continuous drop began during the Great Recession in 2007. It has continued steadily since.
One of the biggest shifts is the steep decline in teen births. In 1991, about 62 of every 1,000 teenage girl had a child. This number has now fell to just under 13 by 2024. This is a historic low that reflects a positive shift, better education, access to contraception, and changing attitudes about early parenthood.
Similar trend is seen among women in their 20s, as the rates their too have dropped. In 2007, about 106 of every 1,000 women aged 20 to 24 gave birth. By 2024, the number has dropped to around 57. For women aged 25 to 29, the rate fell from 118 in every 1,000 women in 2007, to 91 in 2024.
Though there has been a slight rise in births among women in their 30s, experts say that it is not enough to offset the overall decline.
“One of the big questions is all these births that haven’t occurred—are they just being delayed?” asked Ken Johnson, a demographer at the University of New Hampshire. “Or are a lot of these births going to be forgone entirely?”
The answer has significant public health implications. A shrinking younger population could lead to fewer caregivers for an aging society, higher burdens on healthcare systems, and a smaller workforce contributing to national health programs like Medicare.
As per experts, while people still want children, there is a lingering financial burden and social barriers too that get in a way. High student loans, debt, and the rising coast of child care, unstable housing, along with limited access to paid parental leave are all major concerns.
“People don’t have kids when they don’t feel good about their own futures,” said Karen Benjamin Guzzo, a family demographer at the University of North Carolina.
Some political leaders are proposing measures to encourage parenthood. Former President Trump, for instance, has suggested “baby bonuses” and scholarships for married couples or parents. However, Johnson believes that without stronger, systemic support, the U.S. birth rate is unlikely to bounce back to replacement level.
Immigration may help slow the effects of falling birth rates. Many immigrants move to the U.S. with plans to start families, Johnson noted. “They bring the potential for babies in the future.”
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