Heart disease is the leading cause of death among women, yet sex-specific cardiovascular risks often go unrecognized.Four medical societies — the American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists, and Society for Maternal-Fetal Medicine — have issued new guidance to help clinicians identify these risks early and improve heart health in women and girls.The guidance highlights heavy periods, irregular menstrual cycles and pregnancy complications as potential indicators of cardiovascular risk. It also introduces a “Female Life Stages” framework to guide prevention from puberty through menopause and beyond.“Women experience their health care across clinical specialties, but it often is fragmented or disconnected,” said Sadiya S. Khan, chair of the collaborative writing group and professor of cardiovascular epidemiology at Northwestern University Feinberg School of Medicine in Chicago.What Does The New Guidance Include?Progress in preventing cardiovascular deaths among women has stalled over the past two decades. The new framework identifies four life stages as opportunities for early risk detection and prevention.Perimenarche (ages 8–15): The transition around the first menstrual period.Ovarian cycling (ages 15–44): The stage when regular ovulatory and hormonal cycles are established.Perimenopause (ages 45–51): The transition marked by irregular cycles and hormonal changes.Postmenopause (age 51 onward): The years after menopause, defined as 12 months after the final menstrual period.Pregnancy, at any stage, is also described as a biological “stress test” that can reveal previously unrecognized cardiovascular risks.Women's Heart Risks: Heavy Periods And Irregular CyclesThe guidance recognizes menstrual patterns as a female-specific vital sign. Heavy or irregular bleeding may indicate cardiovascular risk, including risks associated with polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS).Women's Heart Risks: Perimenopause And Postmenopause Changes in cholesterol and metabolic health during perimenopause may signal rising cardiovascular risk. Early identification and preventive action may help reduce future risk.The years after menopause can also account for up to 40% of a woman’s lifetime. Most heart attacks, strokes and heart failure events occur during this stage, according to the guidance. More than 80% of these events are considered preventable through early action.Women's Heart Risks: Pregnancy Complications And Mental HealthAnxiety, depression and eating disorders can contribute to poorer cardiovascular health. The framework urges clinicians to consider psychosocial factors alongside hormonal and cardiovascular health.High blood pressure, preeclampsia, gestational diabetes, preterm birth, small-for-gestational-age infants and stillbirth are recognized as female-specific cardiovascular risk enhancers.The 2026 American Heart Association/American College of Cardiology cholesterol guideline also includes pregnancy-related factors in cardiovascular risk assessment.Only about 60% of U.S. women with high blood pressure-related pregnancy complications receive follow-up care for their blood pressure within six months of delivery. The collaborating societies are calling for action to close this gap and ensure cardiovascular risks identified during pregnancy receive continued attention.Need For Dedicated Women's Heart Care CentersThe societies propose a national network of Comprehensive Centers of Excellence for Women’s Cardiovascular Care, focused on clinical care, professional education, research and community engagement.They also call for greater inclusion of women in research, increased funding for women’s health and better translation of evidence into clinical practice.