In a bid to address ‘overuse’ of psychiatric medications, US Health Secretary Robert F. Kennedy, Jr has launched a new plan that aims to promote appropriate psychiatric prescribing and drive deprescribing when clinically indicated. Kennedy announced the efforts to curb psychiatric overprescribing at a MAHA Institute summit on mental health and overmedicalization. “Today, we take clear and decisive action to confront our nation’s mental health crisis by addressing the overuse of psychiatric medications—especially among children,” said Kennedy. “We will support patient autonomy, require informed consent and shared decision-making, and shift the standard of care toward prevention, transparency, and a more holistic approach to mental health,” he added.Agencies within the US Department of Health and Human Services (HHS) are collaborating to leverage their collective expertise and align their efforts to evaluate prescription patterns for psychiatric medications, their benefits and potential harms, and to elevate the role of non-medication treatments and scalable, evidence-based solutions to improve mental health. The HHS has planned a multipronged approach, including education and outreach, program and policy actions, and research-to-practice efforts, to prevent the unnecessary initiation of psychiatric medications and support the tapering and discontinuation for patients not experiencing clinical benefit.Also read: Ibogaine: Why Donald Trump Is Pushing US FDA To Fast-track This PsychedelicSSRI's The Main TargetKennedy has long signaled that reducing the use of psychiatric drugs would be an aim of his tenure.The initiative focuses on the most widely prescribed class of psychiatric medications, first-line treatments for depression and anxiety that include Zoloft, Lexapro, Paxil and Prozac. In 2025, 16.6 percent of U.S. adults, or roughly one in six, reported currently taking an SSRI, the New York Times reported. SSRIs—short for selective serotonin reuptake inhibitors—are among the most widely prescribed antidepressants in the world. The drugs work by increasing serotonin, a neurotransmitter that plays a role in mood regulation, emotional processing, and impulse control. By preventing serotonin from being reabsorbed too quickly, SSRIs maintain higher levels of the chemical in the brain, which can improve symptoms of depression and anxiety for many patients.Like any medication, SSRIs come with side effects—such as nausea, sexual dysfunction, and insomnia—but they are generally considered safe and effective when prescribed appropriately.Experts Welcome But Raise Concerns Over GapPsychiatry experts have welcomed the new federal efforts toward improving psychiatric healthcare. They also raised concerns, including potential overemphasis on overprescribing, while access to mental healthcare remains inadequate. Deprescribing “simply means that if any treatment is not proving itself to be beneficial, or if problems with tolerability substantially outweigh efficacy, it makes sense to discontinue that treatment and replace it with a more effective viable alternative,” said Dr. Joseph F. Goldberg, clinical professor of psychiatry at the Icahn School of Medicine at Mount Sinai in New York City, CNN reported. Dr. Theresa Miskimen Rivera, president of the American Psychiatric Association (APA), said the group supports the administration’s plans for further investment, research, and clinical training. “However, we do have an issue with the framing of mental health as a primary problem of overmedicalization,” Rivera added. “This type of characterization really oversimplifies a very complex, larger issue.” Read More: Robert F. Kennedy Jr. Denies Link To Measles Outbreak At Senate Hearing“This oversimplification of our mental health does not take into account things like persistent workforce shortages, limited psychiatric beds, inadequate visit time, barriers to psychotherapy and social support, and insufficient integration of psychiatric expertise in primary care,” added Rivera, who is also a clinical professor of psychiatry at Rutgers Robert Wood Johnson Medical School.