We know that antidepressants are used to treat mental health illness, especially depression. However, as reported in the Independent, a royal family member Thomas Kingston who was prescribed antidepressants, the same medicines, caused a woman to become severely suicidal.

She is a 48-year-old woman Lingling Wang, who told The Independent that she was not made adequately aware of the potential effects of taking antidepressants before she was prescribed them for insomnia and mild anxiety last January. She said, "My life is finished – I lost my job, almost all my friends, I’m bedridden, I have to rely on my family to feed me.”

She is sharing her story as a coroner issued a warning about the potential effects of medications used to treat depression. Last month, the coroner concluded that Kingston, the husband of Lady Gabriella Kingston, daughter of Prince and Princess Michael of Kent, tragically took his own life due to an adverse reaction to antidepressants.

Experts believe that this is because antidepressants are "overprescribed" in the UK. This has raised serious concerns over the side effects and difficulties a patient faces coming off the medications.

The Independent also found that almost 200 alerts in a decade were made to the UK's medicine regulator over deaths linked to citalopram and sertraline, both of them are antidepressant, which were prescribed to Wang and Kingston.

The Medicines and Healthcare Products Regulatory Agency (MHRA) has announced the review of safety warnings for 30 antidepressants, which includes citalopram, sertraline and mirtazapine.

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A Patient's Struggle with Antidepressant Side Effects

Ms. Wang, from Surrey, shared her experience with antidepressants, which began when her NHS GP prescribed mirtazapine. Despite this treatment, her insomnia persisted, and she developed severe anxiety and low mood. She was then advised to taper off mirtazapine, a process she described as difficult and anxiety-inducing, before transitioning to citalopram.

On citalopram, she reported feeling as if her brain had “completely frozen.” This led to another tapering process and a prescription for sertraline, which worsened her symptoms. Feeling overwhelmed and unsupported, Ms. Wang flew to China to stay with her parents, where she received care from a psychiatrist who helped her discontinue the medication safely. She stated she might not have survived without this intervention.

Need for better patient warnings

Ms Wang has also joined her voice with Lady Gabriella Kingston, to advocate for better patient warnings about the side effects of antidepressants. She also emphasized the importance of patients being fully informed about the risks associated with these medications.

What are the side effects?

The common side effects include: nausea vomiting, indigestion, diarrhea, constipation, low sexual drive, dry mouth, blurred vision, and could increase risk of bleeding by affecting platelet clotting. It also can interfere with blood sodium levels, which can cause headaches, confusion, nausea, vomiting, and drowsiness. Unable to moderate these symptoms, one can feel worse by antidepressants. This is why advocacy and awareness around it is important.

We have all have experienced fevers, there are many different beliefs about it in different cultures and multiple ways to treat it, ranging from modern medicine to ancient practices. When one has a fever, their body feels warm and weak, they also do not have energy to do extended movements. As fevers are a range, some being slight to others being signs of dangerous conditions, dealing with them can be tricky. Things like fever dreams, conversations and thoughts are often incoherent. There are things called fever hallucinations as well, but why does this happen?

Fever means your body temperature has gone above what's normal. But what's "normal" can be a bit different for everyone and can change based on how active you are and the time of day. Generally, a fever is when your temperature is higher than 99 degrees Fahrenheit in the early morning or above 100 degrees Fahrenheit at any other time.

Do Fevers Make Us More Irritable?

In a 2013 review published in the Journal of Pain and Symptom Management, the researchers found that not only do fevers cause people to feel cold, weak and other bodily sensations, but the participants also expressed emotional changes, vivid dreams/hallucinations.

In one of the interview with a participant from the study, researches noted them experiencing feelings of anxiousness, crabby, angry and frustrated, “Like I said, I think fever is really tied in to how you feel emotionally. Because I know every time I have a fever, I just get snotty, for lack of a better term, because I'm just really agitated.”

“I feel tired. I feel irritable”

How Is Body Heat And Brain Health Connected?

Harvard Heath explains a part of your brain called the hypothalamus acts like a thermostat for your body. When you're healthy, it keeps your body at its usual temperature. A fever happens when the hypothalamus gets set to a higher temperature than normal. This change in the brain's thermostat is usually caused by tiny things in your blood called pyrogens.

According to a 2023 review by Yale School of Medicine heat can change things in the environment, it can also change how our brains work. In a study, researchers found that even small increases in temperature while the brain is active can really change what the brain does, and sometimes these changes can be negative.

Experts from Yale explain that changes in temperature in the brain also affect how our nerve cells (neurons) fire signals. These cells have tiny pumps that give them electrical energy, which they release when the brain is active. The researchers found that if brain cells get heated up too fast, faster than these pumps can adjust, the cells might become more active or less active than usual.

Even tiny temperature changes from brain stimulation can lead to big changes in neuron activity. As neurons get warmer, they can even stop working, and when they cool down again, they can become very easily excited.

Fever Hallucinations and other Psychological Affects

According to an Infections & Chemotherapy 2022 review, fevers can cause febrile convulsions, which is a seizure caused by a fever in young kids. It can also cause confusion, like not understanding where you are, not recognizing your surroundings. It can also cause unstable emotions, conscious and cognitive disturbances like illusions on hallucinations.

These can also be symptoms for things like influenza infections or encephalitis. Like the Yale experts explained even small temperature changes can have such a big impact on brain activity, we need to start paying attention to these small changes. He points out that it's a basic rule of physics that when you send electricity through wires to stimulate the brain, you will create heat, both in the wires and in the brain tissue itself.

Researching more on these matters can help us find better treatments and help doctors change the course of several procedures to help their patients.

Turkey has banned elective caesarean surgeries for childbirth at private hospitals and healthcare centres. "Planned Caesarean sections cannot be performed in a medical centre," said a gazette entry outlining new regulations governing private healthcare institutions in Turkey. It came as the country's president, Tyyip Recep Erdogan, has been pushing hard to have women give natural births, asserting that C Section surgeries promoted Western culture.

The move has triggered massive criticism from the opposition and right-wing organisations. "As if the country had no other problems, male football players are telling women how to give birth," Gokce Gokcen, deputy chair of the main opposition CHP, on X. Meanwhile, many human rights and women's rights organisations have also raised their voices against this new law, calling it out for restricting women's rights and liberty.

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What Is A C-Section Birth?

C-section or caesarean birth is a surgical procedure wherein a baby is delivered through incisions made in mother's abdomen and uterus. The name caesarean comes from the Latin word "caedare" which means "to cut." Interestingly, there are rumours that link the name to Roman emperor Julius Caesar, stating that he was the first person to be born via this procedure. However, there are no records of this.

However, there are many cases where a caesarean section surgery becomes almost necessary. A doctor may order a C-section if:

• Your baby is breech, or the lower part of the body is in the birth canal instead of the head.
• Your baby is in a transverse position, or lying sideways in the birth canal.
• Your baby’s head is unusually large.
• Your baby’s heartbeat is slowing down, or there is a problem with oxygen delivery to your baby.
• You are giving birth to more than one baby. Sometimes one baby will be in an abnormal position, so all of the babies are then born via C-section.
• Your baby has a birth defect that makes vaginal delivery unsafe.
• You have umbilical cord issues.
• You have health conditions that make vaginal delivery unsafe. These include high blood pressure, HIV, open herpes lesions, or heart problems.

What Are The Complications Of Having a C-Section Surgery?

There are many complications that come with this method of delivering a child. They include:

• Reactions to the medicines used during surgery
• Bleeding
• Abnormal separation of the placenta, especially in women with previous cesarean delivery
• Injury to the bladder or bowel
• Infection in the uterus
• Wound infection
• Trouble urinating or a urinary tract infection
• Delayed return of bowel function
• Blood clots

Bottom Line

Despite the potential risks and complications, C-sections are much safer than they once were. With evolution in medical science, doctors are now taking great care to make incisions that will reduce the risk of nicks to the baby and infections to the mother. Meanwhile, the use of anaesthesia, also reduces the pain of the childbirth.

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Being dishonest doesn’t come naturally to people, it is a learned virtue, whether out of necessity or pleasure. When kids lie, a lot of it stems from them not wanting to get in trouble, for example, breaking a household item or doing something they were told not to do like running around inside the house. However, when people do learn to tell lies, it can become like a go to tendency for many. It is easier to make something up rather than explaining complex truths.

According to a study published in the Psychological Science 2015, kids start lying around the age of two to three years old. Their habit then progresses rapidly, till the age of 3 and 7.

Not all lies are the same, some are really small and don't hurt anyone, like saying you like someone's new haircut even though you don't. These little white lies often just help keep things smooth and make people feel good. Then there are much bigger lies, like saying someone else did something wrong when they didn't, or lying to people about money. These kinds of lies can cause a lot of damage and have bad consequences for people's lives.

Stress Response of Lying

When we know that being dishonest could really hurt how others see us, the act of lying itself makes our bodies feel stressed. When we tell a lie, things start to happen without us even thinking about it. A 2015 review published in the Current Opinion in Psychology explains that our heart might beat faster, we might start to sweat a little and our mouth can feel really dry. These physical changes are what those old-fashioned lie-detector tests used to try and pick up on.

Some people don't feel as much empathy as others, and they might not have the usual stressed reaction when they lie. The American Psychological Association explains that some people can learn to control their bodies really well and might be able to lie and still pass a lie-detector test. On the other hand, someone who is telling the truth but is just really nervous about being tested might look like they are lying.

Gut-Brain Connection and Extreme Reactions

While it's not common, some people might have a really strong physical reaction to lying, like feeling sick to their stomach or even throwing up a lot. This shows how connected our gut and our brain are. When we feel really anxious, like when we are worried about getting caught in a lie, it can actually make our stomach feel bad. So, for someone who is constantly lying and worried about it, this anxiety could potentially lead to physical sickness.

Living a life where you are often not telling the truth can actually take a toll on your health over time, not just in the moment. Research has suggested that people who lie a lot might have problems like high blood pressure, their heart might beat faster more often, their blood vessels could get tighter, and they might have more stress hormones in their bodies on a regular basis.