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Diabetes is a chronic disease, and many patients present with classic symptoms of the disease: increased thirst and urination and unintended weight changes. However, there's a less apparent connection between diabetes and frequent infections. These recurring infections may actually be a warning sign of unchecked blood sugar levels, often before a diagnosis. Early recognition can lead to earlier detection and management, possibly avoiding severe complications in the future.
Diabetes makes a conducive environment inside the body where harmful microorganisms can easily find a niche. Thus, persons with diabetes get more easily susceptible to bacterial, fungal, and viral infections. People with diabetes usually have a blunted immune response due to blood sugar elevation which affects the regular mechanisms of their body for proper defense. Because of the resultant poor immunity plus reduced circulation along with nerve impairment, infections occur and deteriorate rapidly.
A high glucose level in blood and tissues is conducive for the growth of bacteria and fungi. For example, Candida yeast infections, athlete's foot, and jock itch are commonly reported among those with diabetes.
High blood sugar compromises the ability of white blood cells to fight infections. This form of immunosuppression renders the body susceptible to recurrent and severe infections, such as respiratory and urinary tract infections (UTIs).
This commonly results in diabetic peripheral neuropathy and vascular complications. Low blood flow translates into reduced oxygenation and nutrient supply to extremities such as hands and feet, thus predisposing a patient to a higher risk of slow-healing wounds and eventually to infections. In chronic diabetes, nerve damage is known to impede the emptying of the bladder, predisposing the patient to urinary tract infections.
People with diabetes are at a higher risk for several types of infections, such as:
Conditions like boils, styes, and cellulitis are more common in people with diabetes. These infections can become worse rapidly if left untreated.
Caused by Candida, yeast infections are very common and occur in the mouth (oral thrush), genitals, and skin folds.
Diabetes predisposes to cystitis because of incomplete emptying of the bladder and high sugar content in the urine, which favors bacterial growth.
Influenza, pneumonia, and sinus infections are more severe and frequent in diabetic patients.
Diabetic foot infections can be dangerous; they often begin with minor wounds, such as cuts or blisters, that fail to heal. In severe cases, infections may necessitate amputation if left untreated.
Recurrent infections can be a very early symptom of diabetes. Factual symptoms include:
- Recurrent fever over 101°F
- Persistent sore throat or cough
- Pain and swelling or redness around wounds
- Foul-smelling urine or frequent urination
- Skin rashes or slow-healing sores
- Nausea, diarrhea, or unexplained fatigue
Also Read: 3 Lesser Known Risks Related To Diabetes In Men
Prompt medical attention is crucial when infections arise in diabetic individuals. Diagnosis typically involves blood tests, urine analyses, and wound cultures to identify the infection source. Treatment often includes:
Mild infections may clear up in days, but severe infections can take weeks and require intensive treatment.
The best way to prevent infections is by managing diabetes. Here are some tips:
If you experience frequent infections, unexplained wounds that do not heal, persistent fatigue, or other symptoms such as blurry vision and excessive thirst, you should see a healthcare provider. Early intervention can help manage blood sugar levels and prevent complications. Do not wait for the symptoms to worsen; seek medical advice promptly.
Understanding the link between diabetes and frequent infections is vital for early diagnosis and intervention. Left untreated, recurrent infections can lead to severe complications, including hospitalizations and even amputations in extreme cases.
Frequent infections should never be dismissed as trivial or unrelated symptoms. They might just be your body's way of signaling an underlying issue like diabetes. Taking proactive steps toward diagnosis and management not only improves quality of life but also reduces long-term complications. So, if you or a loved one experiences recurrent infections, it's time to see a healthcare provider and take charge of your health.
Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management. Diabetes Metab Syndr Obes. 2015
Diabetes and Skin Complications. American Diabetes Association.
Type 2 Diabetes and its Impact on the Immune System. Bentham Science. 2020
Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab. 2012
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Dementia is a condition that devastates many people across the globe. According to the World Health Organization (WHO), in 2021, 57 million people had dementia worldwide and 60% of them were living in low and middle-income countries. Dementia is the result of various injuries to the brain, and it is the seventh leading cause of death globally.
While the symptoms of dementia are well-known and understood, a way to cure it has not been made yet. The risk factors include family history, lifestyle choices etc. So, there can be a touch and go reason as to why someone developed dementia. However, a new study has revealed a way to cut the risk of this condition.
According to the Cleveland Clinic, dementia can be influenced by several other issues like inflammation, thyroid problems etc. So, if one can control these issues, does that slash the risk of dementia?
A study published in the Nature Medicine April 2025 has discovered that if people take steps to get their high blood pressure under better control, they might be able to lower their chances of developing dementia quite a bit – by as much as 15%. What's interesting is that this study also found that making two specific changes to what people eat can play a big part in achieving this lower risk. This suggests that managing blood pressure isn't just about taking medicine; what we eat every day can also have a significant impact on protecting our brains from dementia later in life.
Researchers conducted a study over four years with a large group of people living in rural parts of China. They included almost 34,000 adults who were 40 years old or older. The researchers divided these people into two groups. One group, with about 17,400 people, received special help to manage their high blood pressure.
This help included getting blood pressure medication, learning how to check their blood pressure at home, and getting advice on how to live a healthier lifestyle, like losing weight, eating less salty food, and drinking less alcohol. The other group just received the usual medical care for their blood pressure.
The people who received the more intense help to manage their blood pressure not only had a 15% lower chance of being diagnosed with dementia during the four years of the study, but they also had a 16% lower chance of experiencing cognitive impairment.
Cognitive impairment means having difficulties with important brain functions like thinking clearly, remembering things, and solving everyday problems. This shows that really focusing on getting high blood pressure under control can have a big impact on protecting people's brain health and reducing their risk of these serious conditions.
In their report, they strongly suggested that the methods they used in the study – which included medication and lifestyle advice – should be used more widely across the world. They believe that if more people with high blood pressure received this kind of comprehensive care, it could significantly reduce the number of people who develop dementia globally, which is a huge concern for public health.
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Sometimes serious health issues fail to get recognized due to their simple symptoms. Many times, things as simple as a persistent cough, or a fever, can end up being a sign of a concerning health issue. Since we deal with these issues on a daily basis, people often do not get them checked out by a doctor; instead, they choose to stay home and recuperate.
However, having information about the same goes a long way. Experts explain these symptoms and issues to people on various platforms, like social media or governmental portals. One such warning was issued by the National Health Service, England (NHS) about a common warning sign, that many people experience after eating.
NHS says this feeling of ‘heartburn’ could actually be one of the "least-recognised" signs that someone might have cancer. What's concerning is that a large majority of people in Britain, around 79% according to their findings, would not even think that this particular symptom could be a signal of a deadly disease growing inside their body. This lack of awareness means that crucial early warning signs could be easily overlooked, potentially delaying diagnosis and treatment, which can have serious consequences for the outcome of the illness.
A new survey that was carried out by NHS England revealed a worrying trend: many of the initial warning signs that could point towards cancer are being easily missed by the general public. One of the key examples they highlighted is heartburn and indigestion. These are feelings that a lot of people experience from time to time, often as a result of eating too much, eating their food too quickly, or consuming certain types of foods that don't agree with them.
However, the NHS experts are emphasizing that heartburn that persists for a period of three weeks or even longer could be an early indication of oesophageal cancer. This is a particularly dangerous form of cancer that sadly leads to the deaths of around 8,000 people in the United Kingdom every single year, making early detection absolutely vital for improving survival rates.
To get a better understanding of what the public knows about cancer symptoms, NHS England conducted a survey that involved a significant number of people, around 2,000 individuals in total. The results of this survey were quite revealing. They found that heartburn, specifically heartburn that lasts for three weeks or more, was the cancer symptom that people were least likely to recognize as a potential warning sign.
Eight out of every ten people who were surveyed, which translates to 79% of the participants, did not identify this persistent heartburn as something that could possibly indicate cancer. However, heartburn wasn't the only symptom that wasn't widely recognized. The survey also showed that more than half of the people didn't recognize blood in their urine (even if it happened just once), nearly half didn't recognize unexplained weight loss, and over four in ten people didn't recognize an unexplained lump anywhere on their body as a potential sign of cancer.
NHS England advises contacting your doctor if you notice any of the following: lumps, changes in moles, blood in poo or pee, unusual bleeding, a cough lasting three weeks or more, mouth sores that don't heal, tummy trouble, unexplained tiredness, ongoing heartburn, unusual poo, unexplained pain, or bloating.
Other less common signs of oesophageal cancer include trouble swallowing, feeling sick, a persistent cough, a hoarse voice, loss of appetite or weight loss without trying, tiredness, throat or chest pain when swallowing, and black poo or coughing up blood.
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When Todd Engel, based in Maryland, first noticed a change in his vision, he did not think it would change the rest of his life. However, within months, the 62-year-old went from working a full-time job and driving to becoming legally blind in both eyes. Now, Engel is suing Novo Nordisk, the manufacturer of Ozempic - the drug he believes took away his vision.
Engel was prescribed Ozempic in 2023 to help manage his type 2 diabetes. After four months later, he was diagnosed with nonarthritic anterior ischemic optic neuropathy (NAION). It is a rare condition where blood flow to the optic nerve is blocked and causes sudden and irreversible vision loss.
"He made a comment to me about how it’s painful to know he’s never going to see his wife smile again," said Engel’s attorney Jonathan Orent, who spoke to NBC News. "But he knows her voice so well, he can tell when she is smiling."
As per the American Academy of Ophthalmology, NAION affects about 10 in every 100,000 people over the age of 50. For Engel, the diagnosis meant that he no longer would work his job as a motor equipment operator. He also lost his ability to drive and the way he connects with his family.
Filed in New Jersey’s Middlesex County Superior Court, the lawsuit accuses Novo Nordisk of negligence, alleging the pharmaceutical giant failed to properly warn users about the potential risk of NAION. Engel's legal team argues that the company was aware of the condition during early clinical trials but still chose not to include it in the warning label.
“Nothing was or is stopping Defendant from adding a warning regarding the risk of NAION,” the lawsuit states.
Had Engel known about a potential link between Ozempic and blindness, Orent said, he would have chosen a different medication. “There are a wide number of medications that can be used to treat diabetes — and treat it effectively,” Orent said to NBC News.
Ozempic, and its active ingredient semaglutide, is part of a class of drugs known as GLP-1 receptor agonists, initially designed to treat Type 2 diabetes but now widely used for weight loss. Recent studies have hinted at a possible link between semaglutide and NAION — though causation hasn’t been confirmed.
A 2024 study which analyzed six years of medical records from Boston patients found that people with diabetes who took semglutide were four times more likely to be diagnosed with NAION.
Even more striking, overweight or obese people without diabetes who took the drug were over seven times more likely to be diagnosed with NAION.
However, researchers noted this study wasn’t a randomized clinical trial and said more investigation is needed before drawing conclusions.
In February 2024, a separate paper published in JAMA Ophthalmology reported a more modest increase in the risk of NAION for people with diabetes on Ozempic. Like the earlier study, it also stressed the need for further research.
Novo Nordisk's spokeperson told the NBC News that current evaluations, including internal safety reviews and a study from the University of Southern Denmark found no causal relationship between NAION and Ozempic.
The company said that NAION is not listed as an adverse drug reaction. “This also relates to eye conditions, which are well-known comorbidities for people living with diabetes,” the spokesperson said.
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