Melatonin and Heart Failure: Could This “Natural” Sleep Supplement Be Causing Adverse Effects on Your Heart?

Melatonin and Heart Failure: Could This “Natural” Sleep Supplement Be Causing Adverse Effects on Your Heart?

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Updated Nov 6, 2025 | 09:19 AM IST

SummaryA new, yet unpublished study to be presented at the American Heart Association conference links long-term melatonin use to a 90% higher risk of heart failure. Experts urge caution, noting it’s observational and not causal. The study analyzed records of 130,000 insomnia patients, sparking debate over melatonin’s safety and long-term effects.

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