The Union Health Ministry has confirmed that a batch of Coldrif cough syrup made at a Tamil Nadu facility contained diethylene glycol (DEG) beyond safe limits. Earlier samples collected in Madhya Pradesh tested negative, but contamination was detected when Tamil Nadu authorities examined the products directly at Sresan Pharma in Kanchipuram.

Several states have now banned the syrup, and the Centre has ordered inspections at 19 pharmaceutical units across six states, the Ministry of Health and Family Welfare (MoHFW) said in an official statement on October 5. But what exactly is diethylene glycol, and should you be concerned?

Read: Cough Syrup Row: Death Toll Rise To 22 As 2 More Children Succumb

Diethylene Glycol Found In ‘Coldrif’ Cough Syrup

Some children with routine cold symptoms such as cough, fever, and mild discomfort were prescribed the locally available Coldrif syrup. Instead of getting better, within a few days, some developed dark urine, extreme fatigue, and signs of kidney failure, as per BBC.

Death reports are also surfacing, with the toll rising. The Tamil Nadu government has issued a notice to Sresan Pharma, asking why its drug license should not be revoked after 14 children in Madhya Pradesh reportedly died from consuming this toxic syrup. The governments of Madhya Pradesh, Uttar Pradesh, and Tamil Nadu have banned Coldrif sales after tests revealed it contained a highly poisonous chemical. The health ministry confirmed that the syrup contained diethylene glycol (DEG), an industrial solvent, which can be fatal even in small doses.

What Is Diethylene Glycol?

According to the World Health Organization (WHO), diethylene glycol (DEG) and ethylene glycol (EG) are industrial chemicals used in antifreeze, paints, brake fluids, and plastics. They are not intended for medicinal use but can enter drugs if contaminated or if industrial-grade raw materials are used instead of pharmaceutical grade ingredients such as glycerine or propylene glycol.

Once consumed, DEG and EG break down into toxic compounds that can harm the kidneys, liver, and nervous system. Tamil Nadu drug officials found that Coldrif contained 48.6% DEG, which is far above safe limits. The Centre has initiated inspections at 19 pharmaceutical units in six states, filed FIRs, and taken regulatory action in multiple regions.

Several children remain hospitalized across states after consuming the syrup. Doctors are providing treatments including dialysis, but they warn that affected children may continue to experience long-term kidney and nerve problems.

How To Know If You Have Been Contaminated With Diethylene Glycol?

Cases of DEG contamination are emerging daily, mostly in children who developed acute kidney issues after taking cough syrup. Common warning signs include:

• Nausea
• Vomiting
• Abdominal pain
• Drowsiness
• Reduced urination

In children, poisoning can escalate quickly to acute kidney failure, seizures, and even death.

Is It Safe To Consume Cough Syrup?

Interestingly, the batch of Coldrif syrup made by Sresan Pharma (Tamil Nadu) tested positive for high DEG levels (48.6%) at the manufacturing site, triggering bans in Madhya Pradesh, Tamil Nadu, and possibly other states. At the same time, samples collected from other locations, such as in MP and Rajasthan, did not always show contamination, suggesting limited batch issues or testing differences. However, to minimize the risk:

• Always follow your doctor’s or pharmacist’s instructions regarding dose and duration.
• Prefer single-ingredient formulations over combinations to reduce the chance of overexposure.
• Avoid expired syrups or those from unreliable sources.
• Seek medical help if symptoms persist instead of increasing the dose yourself.
• Store medicines correctly according to label instructions (temperature, humidity, etc.).

India is the world’s largest producer of generic medicines, often called the “pharmacy of the world.” Incidents like this raise serious public health concerns and could impact India’s global pharmaceutical reputation.

Ben Sasse, former Senator, on Tuesday shared that he has been diagnosed with pancreatic cancer. His diagnosis came at Stage 4.

Is Ben Sasse's Cancer Terminal?

The former two-term senator, 53, revealed this in a social media or X, message: “This is a hard note to write, but since many of you have already sensed something, I’ll get straight to it: Last week I was diagnosed with metastasized, stage-four pancreatic cancer, and I am going to die.”

Stage 4 cancers are terminal and his terminal diagnosis was "hard for someone wired to work and build, but harder still as a husband and a dad," he said.

Stage 4 cancers are terminal because the cancer has metastasized, which means it has spread from its original site or the primary tumor to distant organs and tissues. This makes it extremely difficult to cure with localized treatments like surgery or radiation.

However, the American Oncology Institute does note that stage 4 cancer always does not have to be terminal, especially with breakthrough treatment options like targeted therapy, immunotherapy, or precision medicine. There are now also advanced surgical techniques that use minimal invasion procedures.

Also Read: Ben Sasse Diagnosed With Stage 4 Pancreatic Cancer: What We Know About His Diagnosis

What Is The Chance Of Survival In Stage 4 Cancer?

According to the American Cancer Society, pancreatic cancer makes up about 3 percent of all cancers in the United States but accounts for roughly 8 percent of cancer-related deaths. Most patients are diagnosed at Stage 4, and the disease is widely regarded as largely incurable. Prostate cancer, by contrast, is the second most common cancer among men, and the majority of those diagnosed do not die from it. The five-year relative survival rate for non-metastasized prostate cancer is 97.9 percent, dropping to about 38 percent once it spreads. These figures highlight how early detection and effective treatment options make prostate cancer far more survivable than pancreatic cancer.

What Are The Treatment Options For Ben Sasse At Stage 4 Cancer?

While treatments including chemotherapy, radiation, and in rare situations surgery are available, stage-four pancreatic cancer is still considered largely incurable. The absence of effective early screening contributes to delayed diagnosis, and although a small number of patients, such as Ruth Bader Ginsburg, have lived longer following surgery, these cases are rare. Well-known individuals including Alex Trebek and Aretha Franklin also battled the disease, which remains one of the deadliest cancers in the United States.

Former senator and former University of Florida president Ben Sasse announced on Tuesday, Dec. 23, that he has been diagnosed with terminal stage 4 cancer, as per CNN News.

In the deeply personal message, the former Republican lawmaker from Nebraska described the diagnosis as a “death sentence,” while expressing appreciation for the steady support of his family and close friends.

“I’m fortunate to have incredible siblings and half a dozen friends who are truly like brothers to me. As one of them said, ‘Yes, you’re on the clock, but all of us are.’ Death is a cruel thief, and none of us escape it,” he added.

For many men trying to conceive, testosterone sounds like an obvious answer. It is often linked with strength, vitality, and male health, so the assumption is that higher levels must also support fertility. In reality, the opposite is often true. Medical experts caution that using testosterone, especially without supervision, can interfere with sperm production and quietly lower the chances of becoming a father.

To know more about the same, we got in touch with Dr. Ambavarapu Divya Reddy, Fertility Specialist, Nova IVF Fertility, LB Nagar, Hyderabad.

Can Increasing Testosterone Help You Conceive?

Dr. Ambavarapu Divya Reddy said, the short answer is no. Testosterone is a male sex hormone, but it does not support fertility in the way many people assume. In fact, taking testosterone can work directly against sperm production. For men who want children, using testosterone without expert guidance can quietly reduce fertility rather than improve it. Here is what doctors want patients to understand.

Why Testosterone Does Not Boost Fertility?

Testosterone is fundamentally opposed to male fertility when taken from outside the body. Using testosterone injections, gels, patches, or pellets suppresses the natural communication between the brain and the testicles that keeps sperm production going. Dr Reddy said, “When this system is switched off, sperm counts fall and in some cases drop to zero. Fertility declines instead of improving.”

This is why men who plan to have children should never begin testosterone therapy without speaking to a specialist.

How Does Sperm Production Work?

Sperm are produced in the testicles with the help of testosterone that is made inside the testicles themselves. This internal testosterone is tightly controlled by the brain through a hormone called luteinizing hormone, or LH.

Dr Reddy told us, when external testosterone is introduced into the body, the brain senses enough hormone is present and stops releasing LH. As a result, the testicles reduce their own testosterone production and sperm production slows or stops altogether.

In real-world practice, many men on testosterone therapy develop extremely low sperm counts or complete absence of sperm, known as azoospermia, often without any obvious symptoms. This is a well-recognised cause of male infertility and one that is largely preventable.

Low Testosterone And Fertility: What Doctors Do Instead

If a man truly has hypogonadism, meaning he has symptoms along with low testosterone levels on blood tests, treatment is still possible but must be handled carefully. Current guidelines from the AUA, ASRM, and endocrine societies strongly advise against starting standard testosterone replacement in men who want children in the near future.

Instead, specialists use treatments that can raise testosterone levels while allowing sperm production to continue. These include clomiphene, human chorionic gonadotropin or hCG, and other targeted therapies that stimulate the testicles rather than shutting them down. Updated guidance for 2024 and 2025 stresses identifying the cause of low testosterone and choosing options that protect fertility.

If you think you have low testosterone but want children

a) Do not self-prescribe testosterone.

b) Consult a reproductive urologist or endocrinologist.

c) Ask about fertility-preserving treatments such as clomiphene or hCG and consider sperm banking if timing matters.

d) If you have already used testosterone, request a semen analysis and hormone tests. Acting early can help guide recovery or fertility treatment.

Testosterone may seem like an easy solution, but external testosterone is a common and avoidable cause of male infertility. If having children is important to you, proper testing and specialist care matter. The treatment that relieves symptoms is not always the one that protects your ability to become a father.

A little-known virus is spreading steadily across different parts of the world, prompting growing concern among health experts. Often described as “untreatable” because there is no targeted antiviral medicine available, adenovirus is drawing attention due to how tough it is and how quickly it can pass from person to person.

Eric Sachinwalla, medical director of infection prevention and control at Jefferson Health, has cautioned that while most healthy individuals develop only mild illness, people in high-risk groups may face more serious health problems. This raises an important question: just how contagious is this mystery illness that is spreading?

Adenovirus: How Contagious Is It?

Yes, adenovirus is highly contagious and spreads with ease in several ways. It can pass through respiratory droplets released during coughing or sneezing, close physical contact such as hugging or shaking hands, and contact with contaminated surfaces like toys and towels.

It can also spread through fecal matter, particularly during diaper changes, and in some cases through water. According to the CDC, the virus spreads quickly in crowded settings such as schools and daycare centres and can survive for long periods on surfaces, making good hygiene especially important for young children and people with weakened immune systems.

Who Do Adenoviruses Affect Most?

Adenoviruses can infect people of all age groups, but they are most commonly seen in children under the age of five. In babies and young children, the virus often spreads in daycare environments where close contact is common. Children are also more likely to put shared objects in their mouths and may not wash their hands as regularly.

Among adults, adenoviruses tend to spread in crowded living conditions. People staying in dormitories or military housing may have a higher risk of infection. The virus is also known to circulate in hospitals and nursing homes, as per CDC.

Those with weakened immune systems are more likely to become seriously ill from an adenovirus infection. This includes people who have undergone organ or stem cell transplants, as well as those living with cancer or HIV/AIDS. Individuals with existing heart or lung conditions may also face a higher risk of severe illness.

Adenovirus: What Are The Symptoms Of An Adenovirus Infection?

The symptoms of an adenovirus infection depend on the part of the body affected. Most commonly, the virus targets the respiratory system. When it infects the airways, it can cause symptoms similar to a cold or the flu. These may include:

• Cough.
• Fever.
• Runny nose.
• Sore throat (pharyngitis).
• Pink eye (conjunctivitis).
• Ear infection (otitis media).
• Swollen lymph nodes.
• Chest cold (bronchitis).
• Pneumonia.

Adenoviruses can also infect the digestive system. When this happens, diarrhea may occur, along with gastroenteritis. Gastroenteritis is inflammation of the stomach or intestines and can lead to stomach pain, diarrhea, nausea, and vomiting.

In rarer cases, adenoviruses can affect the bladder or the nervous system. Infection of the bladder may result in urinary tract infections. When the nervous system is involved, it can lead to serious conditions affecting the brain, including encephalitis and meningitis.