The American celebrity doctor, Daniel Gregory Amen, who practices as a psychiatrist and brain disorder specialist in his recent Instagram (doc_amen) video claimed the link between GLP-1 drugs and suicidal thoughts.

"There is brand new research that is concerning regarding the GLP-1 Drugs like Ozempic, commonly used to treat diabetes and obesity," he said. He then went on to cite the Journal of Affective Disorder for their recent study that explored the connection between these medications and suicidal thoughts and behaviors.

He said, "The researched reviewed reports in a very large World Health Organization database. The medication showed up to a 5-fold increase in suicidal thoughts and behaviors."

However, he did go on to say that these findings do not establish a direct cause and effect relationship. However, if you are taking it, you and your healthcare provider must monitor your mental health. In case of any changes in your moods and motivation, you must tell your healthcare provider.

What are GLP-1 Drugs?

They are a class of medications that help manage the blood sugar (glucose) levels in people with Type 2 obesity. Some GLP-1 agonists can also help treat obesity.

They are most often injectable medication, which means you inject a liquid medication with a needle and syringe. The shot is administered in the fatty tissue under your skin and areas of your body that includes your belly, outer thighs, upper buttocks, and the back of your arms.

The Food and Drug Administration (FDA) first approved GLP-1 Drugs in 2005 and research is still on going about their potential use and benefits.

ALSO READ: Semaglutide Drugs Ozempic, Wegovy Don’t Increase Suicide Risk Or Depression, Study Finds

How Does It Work?

GLP-1 is a hormones that your small intestine makes which can do these following functions:

• Trigger insulin release from your pancreas
• Block glucagon secretion (glucagon is a hormone that your body uses to raise your blood sugar levels when necessary)
• Slows stomach emptying: slower digestion means your body releases less glucose from food to your bloodstream
• Increase your satiety

Is There Any Direct Links Between GLP-1 And Suicidal Thoughts

As per the Lancet Study titled Suicide and suicide attempt in users of GLP-1 receptor agonists: a nationwide case-time-control study, GLP-1 drug use was not associated with an increased risk of suicide or suicide attempt.

The study analyzed 1102 cases and 5494 control, with the mean age as 57.4, with 44.6% being men, 67.6% with recent psychiatric history and 51.3% with obesity.

However, another study titled GLP-1 agonists and risk of suicidal thoughts and behaviours: Confound by indication once again? A narrative review that reviewed the potential link of GLP-1 drug to psychiatric side effects found that these drugs can introduce biological and psychological stressors.

The study found that disruptions in homeostasis from quick weight reduction can elevate cortisol - a steroid hormone, also known as the stress hormone and norepinephrine levels - linked to anxiety, which increases your heart rate and blood pressure. However, the study noted that there is insufficient evidence for a direct causal link between GLP-1 drug and suicidal thoughts and behaviors (STB).

The study notes: "The indirect effects related to the metabolic and psychological disturbances associated with rapid weight loss call for a cautious approach. Used carefully in targeted populations GLP-1 agonists may even emerge as protective agents against STB. Therefore, it is crucial to monitor patients during the treatment and screen for preexisting mental health conditions. If detected, appropriate clinical management should be applied."

When we talk about men’s health, prostate care rarely enters the conversation before the age of 50 but waiting that long might mean missing early signs of dysfunction. According to leading health experts, the prostate—a walnut-sized gland central to male reproductive health—starts undergoing subtle changes as early as your 30s. While issues like prostate enlargement and cancer are more commonly diagnosed later in life, the foundation for lifelong prostate health is laid much earlier.

So why should men under 35 be concerned? Because learning, know-how, and making a few sensible health decisions today might avoid chronic issues tomorrow.

Your prostate gland is tiny, yet its function in a man's reproductive system is important. It lies beneath the bladder and encases the urethra, the tube that carries urine as well as semen. The major functions of the prostate are:

Producing Prostatic Fluid: It is a significant fraction of semen. Prostatic fluid holds enzymes, zinc, citric acid, and prostate-specific antigen (PSA), keeping the sperm alive by thinning the semen.

Regulating Urine Flow during Ejaculation: During orgasm, the prostate tightens to avoid urine entering into the semen and to facilitate ejaculation smoothly.

Regulating Hormones: Within the prostate, there is an enzyme 5-alpha-reductase that turns testosterone into dihydrotestosterone (DHT). This hormone affects male secondary sex characteristics such as body hair and deepening voice but also has a major role in the growth of the prostate.

Learning about these processes is key to knowing when things may be headed in the wrong direction—and that includes being able to tell different sorts of prostate disorders apart.

Prostate Enlargement vs. Prostate Cancer: What's the Difference?

One of the most prevalent misconceptions among younger men is mixing up benign prostate enlargement with prostate cancer. Dr. Sridhar Reddy Baddam, Senior Consultant Vascular and Oncointerventions at Hyderabad-based Apollo Hospital, says, "One of the key things that young men should know is the distinction between prostate enlargement and prostate cancer. Benign Prostatic Hyperplasia (BPH) is a non-cancerous, benign enlargement that usually starts developing post-30–35 years.". It can lead to symptoms like frequent urination or difficulty starting the stream, but it’s not life-threatening.”

Prostate cancer, by contrast, is a malignant growth that often shows no signs in its early stages, which makes regular screenings vital—especially if you have a family history of the condition.

The signs can overlap," continues Dr. Baddam, "which is why prevention and early detection are so important. If either condition is caught early, there are more treatment options and better results."

What is the Hormonal Connection?

Hormones, specifically testosterone, bear a profound relationship with prostate health—but not necessarily one men suspect. Dr. Virender K Sheorain, Associate Director, Medanta - The Medicity, describes the nuance, "There's widespread confusion about testosterone and prostate health. Testosterone per se is not the issue; it's how the body metabolizes it. When it metabolizes into DHT, it can affect prostate growth. That's why hormonal balance is crucial."

Men in their 30s should have hormone levels regularly checked, particularly if they're finding it hard to urinate or have decreased libido. The best part? Treatment has improved.

"One of those methods is Prostate Artery Embolization (PAE), which lowers the prostate's blood supply and causes it to shrink over time," explains Dr. Sheorain. "It's a non-surgical treatment that provides symptom relief without much downtime."

Can Exercise Prevent Prostate Issues?

At your 30s, prostate health is perhaps still a distant issue—but the habits you form at this stage are important. Dr. Mousam Dey, Senior Intervention Radiologist, Fortis Hospital Kolkata, points out the increased awareness among young men, "Men in their early 30s are more becoming aware of prostate health, and that's a positive change.". Daily exercise aids in hormone regulation, the reduction of inflammation, and weight control, all of which are connected to a decreased chance of developing BPH as well as prostate cancer.

Exercise, particularly strength training and aerobics, has been associated with lower PSA levels and decreased risk of prostate issues. Inactivity, conversely, can cause hormonal disruptions that speed prostate enlargement.

Early Red Flags You Shouldn't Ignore

The majority of prostate disorders start insidiously. However, as the gland enlarges (either through benign hypertrophy or malignancy), symptoms can start to develop. Men under age 35 should be aware of:

• Frequent urination, particularly at night
• Trouble initiating or stopping the stream
• A weakened or interrupted urinary stream
• Painful ejaculation
• Hematuria or hematospermia

Although these symptoms do not necessarily signify cancer, they are worth bringing up with a urologist for early screening and prevention.

How Small Habits Support Long-Term Protection?

So what can men younger than 35 do to safeguard their prostate health today? Use this as your fundamental guide:

• Shoot for at least 30 minutes of exercise five times a week.
• Add zinc-fortified foods (such as pumpkin seeds and seafood), healthy fats, and antioxidants such as lycopene (in tomatoes).
• If you have a family history, begin PSA screenings earlier—sometimes as early as age 35.
• Stress affects hormones and the immune system, both of which influence prostate function.
• Do not smoke and avoid excessive alcohol use since both are associated with worse prostate results and increased cancer risks.

The prostate can't take center stage in the same way as the heart or brain in early adulthood, but neglecting it until midlife will cost you your long-term well-being. Today's 30-something man is juggling career, family, and health aspirations—and that means staying one step ahead of avoidable diseases such as BPH and prostate cancer. As Dr. Baddam points out, "Awareness in your 30s isn't premature—it's proactive.

Start small. Think big. And remember: Prostate health isn't about age—it's about taking responsibility for your health journey early.

It is not unknown that people worldwide are struggling with mental health issues. However, the more number of cases is a result of more people reaching out for help. However, Australia's data show something concerning, teens, especially girls are struggling.

As per a recent national survey from the Australian Bureau of Statistics found nearly 2 in 5, which makes it 38.8% of individuals, between the age of 16 to 24 years old experienced symptoms of a mental disorder in the previous 12 months.

This has been higher than the last survey which was conducted in 2007. Back then, the number was at 26%.

Another recent study published in Science Direct, titled: All things being equal? Longitudinal patterns of mental disorder symptoms and associations with key social determinants in a large cohort of Australian adolescents, revealed that mental health problems were especially higher in Australian high school students. It was found that 1 in 4 high school students had mental health problems by Year 10. The study also pointed that it was severe among girls.

Tracking Teen's Mental Health

The study published in the Australian and New Zealand Journal of Public Health has revealed a steady and concerning rise in mental health symptoms among Australian teenagers, particularly among girls and gender diverse youth. The research tracked more than 6,500 students from 71 schools across New South Wales, Queensland and Western Australia from Year 7 (ages 12–13) to Year 10 (ages 15–16).

Mental health problems rising with age

Researchers found a significant increase in symptoms of depression, anxiety, and psychological distress over the four years:

• Depression: 17% of students met the threshold for probable depression in Year 7, rising to 28% by Year 10.

• Psychological distress: A similar trend was observed, with 14% of students reporting high distress in Year 7, increasing to 24% by Year 10.

• Anxiety: The proportion of students experiencing moderate-to-severe anxiety grew from 16% to 24% across the same period.

Girls and gender diverse teens most affected

The study found that certain groups were disproportionately affected by poor mental health outcomes. Girls and gender diverse teens not only began with higher symptom levels in Year 7 but also saw a steeper increase in distress over time.

By Year 10:

Girls had 88% higher depression, 34% higher anxiety, and 55% higher psychological distress than boys.

Gender diverse teens had 121% higher depression, 55% higher anxiety, and 89% higher distress than their male peers.

The study also highlighted the cumulative effect of gender and socio-economic disadvantage. Girls from the least affluent families experienced especially high levels of depression and anxiety—beyond what would be expected from either factor alone.

Family income and school advantage also matter

Teens from less affluent families showed a 7% higher rate of depressive symptoms than those from wealthier households. Meanwhile, students attending schools in lower socio-economic areas reported 9% higher anxiety than those at more advantaged schools.

Broader context and comparison with past data

The findings reflect a growing global concern. Although recent national-level data is limited, a 2015 Australian study (Young Minds Matter) reported 14.4% of 12- to 17-year-olds had a mental disorder. The higher rates in the current study suggest a worsening trend across generations—a phenomenon also noted in international research.

While the exact causes are still being explored, contributing factors likely include social media use, climate anxiety, academic pressure, and the lasting effects of the COVID-19 pandemic. Importantly, the gender gap in mental health is not unique to Australia but part of a wider global pattern.

Addressing the gender mental health divide

Reducing gender inequities in mental health requires a multilayered and systemic approach. Research points to multiple underlying causes for poorer mental health among girls and gender diverse teens, including:

• Gender-based violence
• Pressure from unrealistic beauty standards
• Hormonal changes and menstruation
• Differences in family dynamics and social expectations

Lifestyle factors such as screen time and diet

While some of these issues are recognized in the National Women’s Health Strategy, meaningful investment and policy action are still needed. Moreover, solutions must also prioritize gender diverse teens, who face even starker disparities.

Designing support with teens, not just for them

Experts stress the importance of co-designing mental health strategies with young people, especially those from priority groups like girls, gender diverse individuals, and economically disadvantaged teens. Creating culturally safe, inclusive, and affirming support systems is key to helping teens feel understood and empowered—and improving their mental health outcomes in the long run.

In recent days, questions have emerged around the sudden demise of businessman Sunjay Kapur—particularly speculation that he may have accidentally swallowed a bee during a polo match, which then triggered a fatal reaction. While such incidents are extremely rare, they are medically possible under specific conditions.

If someone is allergic to insect venom—or has an undiagnosed heart condition—the ingestion or sting of a bug like a bee can set off a chain reaction within the body. In very rare cases, this can lead to a heart attack or even sudden cardiac arrest.

What Is Kounis Syndrome?

This rare medical condition occurs when a severe allergic reaction—known as anaphylaxis—triggers heart-related complications, including heart attacks. Known as Kounis syndrome, it accounts for just 0.5% to 2% of all anaphylactic cases, making it a rare but dangerous phenomenon.

Kounis syndrome can be caused by various allergens, including insect stings, medications, certain foods, or even unfamiliar environmental triggers. In such cases, the body’s immune response kicks in with the release of histamine and other chemicals to neutralize the threat. However, this same reaction can dangerously dilate blood vessels, drop blood pressure sharply, and deprive the heart of oxygen. This creates stress, especially for those with pre-existing cardiovascular issues.

How Allergic Reactions Impact the Heart

Histamine release during a severe allergic reaction results in widened blood vessels and a sudden drop in blood pressure. When blood pressure drops too low, the heart struggles to supply oxygen-rich blood to vital organs—including itself. This oxygen deprivation can trigger abnormal heart rhythms, known as arrhythmias, and may ultimately result in cardiac arrest.

In more severe cases, anaphylaxis may cause fluid leakage from the bloodstream into surrounding tissues, further lowering blood volume and blood pressure. In individuals with underlying heart conditions, it can also cause the coronary arteries to narrow, reducing the heart's oxygen supply and increasing the risk of a heart attack.

Another potential outcome is plaque rupture—a common cause of heart attacks in people with coronary artery disease. When the plaque lining the artery walls tears or erodes, it can attract blood clots, which block blood flow and damage heart tissue.

Real Cases of Bug-Induced Cardiac Events

Two real-life examples highlight how allergic reactions from insects can escalate into cardiac emergencies.

One case as reported in Indian Express, involved a 31-year-old man working on a bee farm who suffered multiple stings, unaware of his allergy. He had only 40% plaque buildup in his arteries, but the allergic reaction caused the plaque to rupture. Blood clots formed over the tear, blocking the artery, and a stent was required to reopen it.

In another case, a wasp bite triggered a similar reaction, although the patient experienced plaque erosion rather than rupture. This too led to a blockage, though less severe, and did not require a stent.

What to Do in Such Cases?

Immediate medical attention is critical in managing allergic reactions that affect the heart. Patients should be administered steroids or a high-dose adrenaline injection (epinephrine) without delay. Supplemental oxygen must be provided, and an electrocardiogram (ECG) should be performed to assess cardiac function.

While such cases are rare, they underscore the importance of recognizing allergies, especially when combined with underlying heart conditions. Prompt response can be life-saving.