While Type 1 and Type 2 diabetes are widely recognized and studied, scientists have proposed two additional forms - type 3 and type 4 diabetes. Though they are not medically or officially classified by any health organizations, these terms have been gaining attention more and more.

Recently, Health and Me reported on the Type 5 diabetes, which is linked to malnutrition. However, the question is, if we already have type 1, 2, and 5 diabetes, then what are the type 3 and 4?

Let's delve a little deeper into that:

What is Type 3 Diabetes?

Type 3 Diabetes is an unofficial term that is used to describe Alzheimer's disease which is caused by insulin resistance in the brain. Researchers first proposed this classification after observing similarities between the brain changes in Alzheimer's and those caused by diabetes.

In healthy brains, insulin usually supports communication between the nerve cells and also helps regulate energy use. However, in people with Alzheimer's, the brain shows signs of insulin resistance, impairing the brain's ability to use glucose properly. This dysfunction can also lead to memory loss, cognitive decline, and the buildup of proteins like tau and beta-amyloid, hallmarks of Alzheimer's disease.

While Type 3 diabetes is not a formally recognized diagnosis, the idea does throw a light on its important link between metabolic health and brain function.

What are the symptoms?

• Memory loss that disrupts daily life
• Difficulty solving problems or planning
• Trouble completing familiar tasks
• Confusion with time or place
• Problems with language and communication
• Losing items or placing them in odd locations
• Poor judgment or decision-making
• Withdrawal from work or social activities
• Mood swings and personality changes

While some of these changes can occur with age, consistent or worsening symptoms should prompt a medical evaluation.

What Causes It?

The idea of type 3 diabetes is based on how insulin dysfunction in the brain may contribute to neurodegeneration. Several risk factors have been identified:

• Diet high in sugar and fat, low in fiber
• Sedentary lifestyle
• Chronic stress
• Low socioeconomic status
• Genetics, including the presence of the APOE4 gene
• High blood pressure and poor lipid metabolism

These factors can impair glucose delivery to the brain and damage neurons, increasing the risk of dementia.

What is Type 4 Diabetes?

It is also another proposed category that occurs in older adults who develop insulin resistance despite not being overweight. In fact, in a 2015 study that involved mice, suggested that this form of diabetes may be caused by accumulation of immune cells called regulatory T cells, which increase with age. The study is titled: Depletion of Fat Tregs Prevents Age-Associated Insulin Resistance.

Unlike type 2 diabetes, which is also linked to obesity, in type 4 diabetes, lean individuals get affected.

Symptoms of Type 4 Diabetes

• Fatigue
• Frequent urination
• Blurred vision
• Unexplained weight loss
• Increased thirst and hunger
• Slow-healing sores

Because it typically affects older adults with normal body weight, these symptoms may be misattributed to aging or other conditions, leading to underdiagnosis.

What Causes It?

The exact causes of type 4 diabetes are still being studied, but aging appears to play a significant role. Research indicates that excess regulatory T cells may interfere with insulin signaling, leading to blood sugar issues in the absence of typical risk factors like obesity.

In a world where superfoods, supplements, and scientific advances define the health discourse, María Antonia Cuero's story shines for its elegant simplicity. At 123, María is officially the world's oldest living human—informally surpassing the Guinness World Record holder, France's Jeanne Louise Calment, who reached 122 years of age. Though her age remains in process of verification, the insights she offers are incontrovertibly priceless and scientifically validated.

Born on October 18, 1901, in Colombia, María has witnessed two world wars, numerous technological revolutions, and the dawn of modern medicine. Yet when asked what the secret to her remarkable longevity is, María doesn't refer to a magic pill or a genetic mutation. Rather, she attributes her longevity to two humble foods: fish and bananas—cornerstones of her daily diet, steeped in her coastal upbringing.

Growing up in a big family of 10 siblings by the Mayorquín River, María spent her days surrounded by nature. With fresh fish and tropical fruits readily available, her childhood diet was both organic and full of nutrients—years before these words became health buzzwords. Throughout the decades, she also raised eight children and is now the proud matriarch to 26 grandchildren, 24 great-grandchildren, and 54 great-great-grandchildren.

Although not officially documented by the Guinness World Records, María's identification card in 2012 indicates her birth as October 1901. She became the oldest to get vaccinated in March 2021, at 119 years old, marking yet another incredible achievement to her name.

However, aside from age and figures, it is María's way of living and attitude that provide deep insights into longevity.

Maria's Mindset and Philosophy of Longevity

In an interview on the Colombian television show Los Informantes, María discussed her philosophy of life: laugh frequently, don't worry excessively, remain active, and don't sit around too much. In her opinion, physical activity is essential. Her regimen included walking often, swimming, rowing, and being outdoors—long before fitness monitors or gym memberships were the rage.

These principles echo research in contemporary gerontology. Many studies identify an active life and good social relationships with a lower risk of chronic disease and longer lifespan. María's case supports that emotional well-being, combined with activity, is significant in healthy aging.

Fish

Of all the foods that she ate, fish is what María puts so much stress on. Living next to the river as a child, not only was she afforded the fresh catches each day, but she fished herself very frequently. "Good fish. I would fry the fish and then mix it with coconut and rice," she shared with a journalist.

Fish is a good source of high-quality protein, omega-3 fatty acids, vitamins D and B2 (riboflavin), and minerals like calcium, phosphorus, iron, zinc, iodine, magnesium, and potassium. Omega-3s in oily fish, particularly docosahexaenoic acid (DHA), are recognized to lower inflammation, maintain brain health, and decrease the risk of heart disease.

Scientific studies in the Journal of the American Medical Association have indicated that individuals with high levels of omega-3s live as much as 2.5 years longer on average. Another significant study identified a 40% lower risk of coronary heart disease mortality in those who ate regularly from fish with high levels of omega-3s, a figure further supported by the British Heart Foundation.

Bananas

María's second pillar of diet? Bananas—the smaller, sweeter bocadillo bananas (also referred to as sugar bananas or lady finger bananas). These bite-sized fruits are not only tasty but are full of fiber, antioxidants, potassium, and vital vitamins.

Bananas have been valued for centuries for their digestive and cardiovascular benefits. They help to control blood pressure, balance body fluids, and repair muscle and nerve tissue—all highly beneficial for elderly populations. The tryptophan and vitamin B6 contained in bananas also assist with serotonin formation, the "feel-good" neurotransmitter that enhances emotional well-being.

For María, these bananas were an everyday treat. And as science indicates, eating bananas on a regular basis can help with heart health, boost mood, and assist with muscle recovery.

What We Can Learn From Her Habit?

María's remarkable life is not merely about what she ate—it's about the regularity with which she lived. Her life was based on balance: a modest diet, regular exercise, a positive attitude, and close family ties. To this day, she radiates resilience. When asked what she is afraid of, her answer was moving: "I am not afraid of anything anymore."

This lack of fear and deeply ingrained calmness may also have protective health benefits. Studies have linked chronic stress to increased inflammation and a heightened risk of age-related diseases. María’s philosophy—“don’t worry too much”—may offer more protection than we’ve previously realized.

As the world population ages, María Antonia Cuero's life is an eloquent reminder: the route to longevity may not come in the form of costly therapies, restrictive eating, or vigilant self-tracking. It may sometimes be found in age-old secrets—eat fresh, move frequently, laugh without restraint, and enjoy the little things.

As we wait for official verification of her record-setting age, her legacy already walks tall as an example of how simplicity, persistence, and culture can overcome and thrive. In a world filled with constantly changing health fads, María's legacy encourages us to stop for a moment and ask—what really counts when it comes to living a long, healthy life?

Microplastics—those invisible particles of plastic pollution—may be doing more than just contaminating the environment. According to recent findings presented at the American Heart Association (AHA), they could also be silently contributing to clogged arteries, potentially raising the risk of heart attacks and strokes.

In a study that’s turning heads in the medical community, researchers discovered that fatty plaques found in neck arteries—known as carotid arteries—contained over 50 times more microplastic content compared to plaque-free arteries. Even more concerning, these microplastic concentrations were found to be significantly higher in individuals who had already suffered from a stroke, mini-stroke, or temporary vision loss caused by restricted blood flow.

What Exactly Are Microplastics?

Microplastics are extremely small particles—often less than five millimeters in size—created when larger pieces of plastic break down. They can enter the human body in multiple ways: through the air we breathe, the food we eat, and even skin contact. An even smaller subset, known as nanoplastics, measures under 1,000 nanometers and is completely invisible to the naked eye. Because of their minuscule size, these particles can infiltrate tissues, organs, and potentially disrupt biological functions.

The accumulation of microplastics in arterial plaques introduces a new dimension to the ongoing conversation about cardiovascular risk factors. While high cholesterol, smoking, and hypertension remain the usual suspects, environmental pollutants like microplastics are emerging as a stealthy but significant threat.

A Simple Solution In Your Kitchen?

Amid growing concerns about microplastic contamination, especially in drinking water, scientists have been working on practical ways to mitigate exposure. In 2024, a research team from Guangzhou Medical Centre made a breakthrough. They discovered that a common household activity—boiling water—can significantly reduce microplastic content in tap water.

According to the team, combining boiling with basic filtration can remove up to 90% of nanoplastic and microplastic particles (NMPs) from household water. However, the method’s effectiveness varied depending on the type of water used. In areas where tap water contains higher mineral content, commonly referred to as "hard water," the technique proved especially efficient.

The secret lies in limescale. As hard water is heated, it forms limescale—a chalky white substance—which appears to create a sticky layer that traps microplastic fragments. Researchers found this natural process enhanced the removal of plastic particles from water, offering a practical and affordable solution for most households.

While more research is needed to fully understand the long-term health effects of microplastics, early evidence suggests they may be more dangerous than previously thought—especially for cardiovascular health. Taking simple precautions, such as boiling and filtering drinking water, could help reduce exposure and offer a small but meaningful step toward safeguarding your heart and overall well-being.

Reading non-fiction books is not my cup of tea, while they are informative and important to read, when I read for pleasure, I want to immerse myself in a world that could never be. Reading fiction books like the Harry Potter series, Percy Jackson books and others like the Dragon Rider, were the reason I enjoyed reading. Often using these books as a means to escape difficult feelings, I never even realized how reading these books transformed my mental health, along with my perspective.

Reading plays an important role for your mental health; books offer numerous advantages for one's mental well-being. Whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. This piece will explore several key reasons why reading is so beneficial for mental health.

How Does Reading Impact Mental Health?

According to a 2022 PLoS One study, reading fiction can improve people's mental well-being. The researchers conducted five different studies to see how various ways of engaging with fiction affect individuals. These methods includes recalling past fiction reading experiences, being instructed to read fiction, discussing fiction in comparison to non-fiction, and discussing different types of fiction.

The research shows that books had a positive influence on people's mood and emotions. However, it appears that simply reading fiction might not lead to an immediate improvement in mental well-being. The brain seems to require a period of processing and understanding the story before positive effects can be observed.

Ways Reading Can Affect Your Mental Health

Mental Health First Aid England, a social enterprise that offers guidance and training for mental health in workspaces, explains that whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. Here are some ways it helps us.

Reading captivating books brings joy and immersion, making time disappear. Finishing a good story can evoke sadness or eagerness for more, highlighting reading's positive impact.

Reading as a Stress Buster

Engrossing oneself in a book for just six minutes can significantly reduce stress by lowering heart rate and easing tension, outperforming other relaxation methods.

Acts as a Coping Mechanism

Reading offers an escape from the real world, providing a coping mechanism, especially in childhood. This immersion can be transformative, influencing how we interact with the world.

Building Empathy

Reading fiction enhances empathy, improving the ability to understand others' feelings and thoughts, temporarily boosting this crucial social skill.

Keeping Your Brain Sharp

Lifelong cognitive activities like reading slow down memory loss and reduce mental decline in later life compared to less stimulating pursuits.

Finding Support and Healing in Reading Groups

Discussing books in reading groups can significantly improve mental health, aiding concentration, emotional understanding, self-awareness, and meaningful discussions.

Boost Your Sense of Control and Offer a Safe Space

Discussing books fosters a sense of control and independence, benefiting mental well-being. It provides a positive and safe way to process challenging topics.

Understanding Adulthood

Reading for pleasure in adolescence enhances academic performance, social engagement, and personal development, offering insights into adult life.

Boosting Your Intelligence

Research confirms that reading increases intelligence, leading to a larger vocabulary, broader knowledge, and improved verbal skills.