While Type 1 and Type 2 diabetes are widely recognized and studied, scientists have proposed two additional forms - type 3 and type 4 diabetes. Though they are not medically or officially classified by any health organizations, these terms have been gaining attention more and more.

Recently, Health and Me reported on the Type 5 diabetes, which is linked to malnutrition. However, the question is, if we already have type 1, 2, and 5 diabetes, then what are the type 3 and 4?

Let's delve a little deeper into that:

What is Type 3 Diabetes?

Type 3 Diabetes is an unofficial term that is used to describe Alzheimer's disease which is caused by insulin resistance in the brain. Researchers first proposed this classification after observing similarities between the brain changes in Alzheimer's and those caused by diabetes.

In healthy brains, insulin usually supports communication between the nerve cells and also helps regulate energy use. However, in people with Alzheimer's, the brain shows signs of insulin resistance, impairing the brain's ability to use glucose properly. This dysfunction can also lead to memory loss, cognitive decline, and the buildup of proteins like tau and beta-amyloid, hallmarks of Alzheimer's disease.

While Type 3 diabetes is not a formally recognized diagnosis, the idea does throw a light on its important link between metabolic health and brain function.

What are the symptoms?

• Memory loss that disrupts daily life
• Difficulty solving problems or planning
• Trouble completing familiar tasks
• Confusion with time or place
• Problems with language and communication
• Losing items or placing them in odd locations
• Poor judgment or decision-making
• Withdrawal from work or social activities
• Mood swings and personality changes

While some of these changes can occur with age, consistent or worsening symptoms should prompt a medical evaluation.

What Causes It?

The idea of type 3 diabetes is based on how insulin dysfunction in the brain may contribute to neurodegeneration. Several risk factors have been identified:

• Diet high in sugar and fat, low in fiber
• Sedentary lifestyle
• Chronic stress
• Low socioeconomic status
• Genetics, including the presence of the APOE4 gene
• High blood pressure and poor lipid metabolism

These factors can impair glucose delivery to the brain and damage neurons, increasing the risk of dementia.

What is Type 4 Diabetes?

It is also another proposed category that occurs in older adults who develop insulin resistance despite not being overweight. In fact, in a 2015 study that involved mice, suggested that this form of diabetes may be caused by accumulation of immune cells called regulatory T cells, which increase with age. The study is titled: Depletion of Fat Tregs Prevents Age-Associated Insulin Resistance.

Unlike type 2 diabetes, which is also linked to obesity, in type 4 diabetes, lean individuals get affected.

Symptoms of Type 4 Diabetes

• Fatigue
• Frequent urination
• Blurred vision
• Unexplained weight loss
• Increased thirst and hunger
• Slow-healing sores

Because it typically affects older adults with normal body weight, these symptoms may be misattributed to aging or other conditions, leading to underdiagnosis.

What Causes It?

The exact causes of type 4 diabetes are still being studied, but aging appears to play a significant role. Research indicates that excess regulatory T cells may interfere with insulin signaling, leading to blood sugar issues in the absence of typical risk factors like obesity.

Priyanka Chopra and Nick Jonas, we all know them as a power couple. However, there are moments that have broken them and they both have talked about it. This was the moment of their daughter Malti Marie Chopra Jonas' birth.

On February 4 episode of the Jay Shetty Podcast, Jonas, 33, opened up about his daughter's birth. "She came to the world under sort of very intense circumstances, which I have not really talked about ever. She came out, she was one pound and 11 ounces, and purple basically. These angels at the NICU kind of resuscitated her in that moment, got her taken care of really quickly, and intubated and everything else."

Also Read: Shingles Can Strike More Than Once, Vaccination Offers Protection, say experts

In fact, recently a video has been circulating of Priyanka Chopra Jonas talking about the premature birth of her daughter too. She described this period as "tough" and said that it was extremely hard on her. She also called Malti a "miracle baby".

On the Jay Shetty podcast, she revealed that the couple were forced to announce her birth, whereas they wanted to wait till her health gets better. They had put everything on halt and visited the NICU every single day. "We received a text saying that her (Malti) birth would be out in the newspapers, if we don't, they are going to put it in within three hours. So we were kind of forced into announcing her birth because we wanted to control our own narrative. We weren't ready. We didn't know what would happen with her or how she would be."

Malti's Premature Birth

Priyanka shared that she was informed about her premature delivery in the 27th week. This is what made her completely "shut down". She also recalled sitting in front of the fireplace for nine hours and was not able to process the situation.

Like Jonas, Priyanka too noted that Malti was purple at birth and required immediate NICU attention. She also said that the nurses' fingers were too big for her small mouth. She recalled feeling "numb" at that time.

However, Jonas shared that Priyanka and him "had a lot of tough conversations day in, day out about caring" for Malti. He also appreciated his wife's strength on handling the situation. "The way in which she handled it was so inspiring to me, and you know, allowing for those days to be tough, but to be tougher for our little girl was the focus."

Malti received six blood transfusions and gained weight in the hospital. After nearly three and half months, she was able to go home.

Priyanka reveals that in her house there is a "big mandir" with "a large Shiv Ji murti". This is where everyone sat as a family and she cried not out of fear, but out of gratitude. "Gratitude that she survived, that she was home, that she chose us, and that we were able to make it happen. IVF is tough."

Read: What Parents of Premature Babies Must Know About the NICU, According to a Neonatologist

What Parents Of Prematurely Born Babies Must Keep In Mind?

Health and Me had earlier spoken to Dr Sanjay Wazir, Medical Director, Neonatology and Pediatrics at Motherhood Hospitals, Gurugram who pointed out that Neonatal Intensive Care Unit or the NICU may seem overwhelming, however, it must be seen as a sanctuary of healing.

"In the NICU, premature or unwell newborns receive specialized medical attention, constant monitoring, and compassionate care from expert hands. Here, the mother and the baby are well taken care of. This will help the baby lead a healthy life. Hence, NICU care is important for all the premature or unwell babies," he says.

What Happens Inside The NICU?

The doctor explains that the NICU provides a controlled and nurturing environment where babies can grow stronger outside the womb. "It helps maintain their body temperature, supports breathing, and ensures proper nutrition through feeding tubes if necessary," he says.

Every machine in the NICU is for a specific purpose, right from oxygen support to heart rate monitoring, ensuring that each baby receives precisely what they need. Parents often find comfort knowing that the experts in the NICU are constantly watching over their child’s progress, explains the doctor.

The doctor points out that parents are essential part of the NICU journey. "Your touch, your voice, and your calm presence can help your baby feel safe and comforted," he tells to all the parents. However, what is extremely important is to maintain hygiene guidelines, staying involved in daily care, and communicating regularly with the doctors and nurses to "strengthen your bond and confidence as caregivers." The doctor says that during this time, the mother will also be taught about Kangaroo care, which is skin-to-skin contact that helps the mother bond with her baby.

Cases of scrub typhus, one of the deadliest infections affecting multiple organs, or even death, have significantly increased from previous year. Once relevant to people working in fields, new studies show it migrating to human settlements.

In 2025, Andhra Pradesh reported 1,566 scrub typhus cases, and nine suspected deaths, according to data from the Integrated Health Information Platform, Integrated Disease Surveillance Programme (IDSP-IHIP) on 8 December. Followed by Karnataka with 1,870 cases, Tamil Nadu 7,308 cases, and Telangana, 309 cases.

What Is Scrub Typhus?

Scrub typhus, also known as bush typhus, is a bacterial infection caused by bacteria infection, caused by bacterium Orientia tsutsugamushi. It is spread through bites of infected larval mites, Chiggers.

Most cases of scrub typhus occur in rural areas of Southeast Asia, Indonesia, China, Japan, the Indian subcontinent and northern Australia. Until now, it was believed that chiggers only lurked in the tall grasses of remote paddy fields or dense forests. Due to this, it is commonly known as "farmers' disease", only confined to the fields.

However, new PLOS study data revealed the opposite. The study is led by researchers from Christian Medical College (CMC) Vellore and international collaborators and suggests that the bulk of infections are now even occurring within human settlements.

The study monitored over 32 000 people in Tamil Nadu, which led to the conclusion that agricultural activities, long considered the primary risk factor, were only weakly associated with the disease in high-prevalence areas.

How are Human Settlements A Prime Factor?

Risk for scrub typhus is significantly higher for those living in clustered houses or homes with fewer rooms. If the micro environment around the residence is unmaintained, gardens are patched, or even the damp corners of a courtyard, it could lead to breeding ground for the mites and the rodents that carry Chiggers.

Who Is At Most Risk?

It was once believed that working-age men were the most affected, but the new study tells otherwise. According to the new data, women over 60 are at the highest risk of infection.

As women spend most of their time in and around the home, due to household work, from the kitchen to the laundry, these activities are now the primary cross point of contact with infected mites.

What Is the Risk Factor Of Infection?

As initial symptoms of infection, such as fever, headache, and muscle pain, are the same as viral flu or dengue, many first seek help from untrained practitioners or local pharmacies.

By the time they reach the hospital, the disease has already progressed to severe complications like acute respiratory distress syndrome (ARDS), Kidney failure, or Meningoencephalitis, which is inflammation of your meninges and brain at the same time, a life-threatening condition.

Not only this, the researchers revealed that nearly 10 percent of affected households exceed 25 percent of their income in the treatment.

For severe cases, the cost of treatment can be up to approximately INR 110,000, a staggering sum for rural and peri-urban families earning a fraction of that monthly.

Prevention

• Do not let the grass grow tall around your house
• Tightly maintain kitchen gardens and remove piles of wood or debris where rodents (the primary hosts for mites) might nest.
• As chiggers are usually found close to the ground, do not sit directly on the grass or soil. Use chairs or mats. For children, make them wear socks and full- length trousers while playing in the yard.
• If you notice a small, dark, cigarette-burn-like mark, it is usually left behind by mites. It is most likely "Eschar". It is an important critical clue. As the bite is painless, it often goes unnoticed.
• Do a thorough skin check for an eschar, especially in warm, moist areas like the armpits, groin, or behind the knees.

Early intervention is necessary, as if a fever lasts more than two days, don't just treat it as "seasonal fever".

Consult a qualified doctor and specifically ask about scrub typhus. Infection can be treated with doxycycline common antibiotic, in the early stages. The case fatality rate in this study was 1.5 percent, hospital based studies in South India have previously recorded mortality rates as high 30 percent when treatment is delayed

Cases of scrub typhus, one of the deadliest infections affecting multiple organs, or even death, have significantly increased from previous year. Once relevant to people working in fields, new studies show it migrating to human settlements.

In 2025, Andhra Pradesh reported 1,566 scrub typhus cases, and nine suspected deaths, according to data from the Integrated Health Information Platform, Integrated Disease Surveillance Programme (IDSP-IHIP) on 8 December. Followed by Karnataka with 1,870 cases, Tamil Nadu 7,308 cases, and Telangana, 309 cases.

What Is Scrub Typhus?

Scrub typhus, also known as bush typhus, is a bacterial infection caused by bacteria infection, caused by bacterium Orientia tsutsugamushi. It is spread through bites of infected larval mites, Chiggers.

Most cases of scrub typhus occur in rural areas of Southeast Asia, Indonesia, China, Japan, the Indian subcontinent and northern Australia. Until now, it was believed that chiggers only lurked in the tall grasses of remote paddy fields or dense forests. Due to this, it is commonly known as "farmers' disease", only confined to the fields.

However, new PLOS study data revealed the opposite. The study is led by researchers from Christian Medical College (CMC) Vellore and international collaborators and suggests that the bulk of infections are now even occurring within human settlements.

The study monitored over 32 000 people in Tamil Nadu, which led to the conclusion that agricultural activities, long considered the primary risk factor, were only weakly associated with the disease in high-prevalence areas.

How are Human Settlements A Prime Factor?

Risk for scrub typhus is significantly higher for those living in clustered houses or homes with fewer rooms. If the micro environment around the residence is unmaintained, gardens are patched, or even the damp corners of a courtyard, it could lead to breeding ground for the mites and the rodents that carry Chiggers.

Who Is At Most Risk?

It was once believed that working-age men were the most affected, but the new study tells otherwise. According to the new data, women over 60 are at the highest risk of infection.

As women spend most of their time in and around the home, due to household work, from the kitchen to the laundry, these activities are now the primary cross point of contact with infected mites.

What Is the Risk Factor Of Infection?

As initial symptoms of infection, such as fever, headache, and muscle pain, are the same as viral flu or dengue, many first seek help from untrained practitioners or local pharmacies.

By the time they reach the hospital, the disease has already progressed to severe complications like acute respiratory distress syndrome (ARDS), Kidney failure, or Meningoencephalitis, which is inflammation of your meninges and brain at the same time, a life-threatening condition.

Not only this, the researchers revealed that nearly 10 percent of affected households exceed 25 percent of their income in the treatment.

For severe cases, the cost of treatment can be up to approximately INR 110,000, a staggering sum for rural and peri-urban families earning a fraction of that monthly.

Prevention

• Do not let the grass grow tall around your house
• Tightly maintain kitchen gardens and remove piles of wood or debris where rodents (the primary hosts for mites) might nest.
• As chiggers are usually found close to the ground, do not sit directly on the grass or soil. Use chairs or mats. For children, make them wear socks and full- length trousers while playing in the yard.
• If you notice a small, dark, cigarette-burn-like mark, it is usually left behind by mites. It is most likely "Eschar". It is an important critical clue. As the bite is painless, it often goes unnoticed.
• Do a thorough skin check for an eschar, especially in warm, moist areas like the armpits, groin, or behind the knees.

Early intervention is necessary, as if a fever lasts more than two days, don't just treat it as "seasonal fever".

Consult a qualified doctor and specifically ask about scrub typhus. Infection can be treated with doxycycline common antibiotic, in the early stages. The case fatality rate in this study was 1.5 percent, hospital based studies in South India have previously recorded mortality rates as high 30 percent when treatment is delayed