World Health Organisation (WHO) has declared a polio outbreak in Papua New Guinea and called for an "immediate" vaccination campaign. Samples of the highly infectious virus were found in two healthy children during a routine screening in Lae, a coastal city in the country's northeast.

Less than half of the country's population are immunised against the potentially deadly disease, which is close to being wiped out, but has recently surfaced in some parts of the world. "We have to do something about it and we have to do it immediately," said Sevil Huseynova, WHO's representative in Papua New Guinea, warning that the disease could spread beyond the country. We have to make maximum effort to get 100% [vaccination] coverage," Dr Huseynova said at a media conference on Thursday. Polio knows no borders.

Polio is highly contagious and can be transmitted through droplets from sneezing or coughing, as well as through contact with virus-laden faeces, also known as stool. The virus can easily spread and enter the body through the mouth, and it can also be present in water contaminated with feces from a person infected with the poliovirus. In 1994, India launched the Pulse Polio Immunisation Program to eradicate polio, which at the time accounted for about 60% of global cases. In January 2011, the last reported cases of wild polio in India were in West Bengal and Gujarat. Subsequently, in 2014, the WHO declared India polio-free.

You know Joey from the series sleeps without clothes on. Have you ever thought about it? Maybe you have, but you have been too shy to give it a try. Maybe Joey was not joking, maybe sleeping without clothes on do have some benefits.

While sleeping naked at night may not be the first thing that comes to your mind, however, it has benefits, which can surprise you.

Sleeping Naked Means Sleeping Faster

Behavioral sleep disorders specialist Michelle Drerup, PsyD, DBSM, tells Cleveland Clinic that your body naturally works to lowers its temperature or thermostat to doze off at night. This happens through circadian rhythm that regulates your body's wake and sleep cycles. So, the faster you cool off, the faster you will sleep.

Sleeping without clothes might as well help you in that.

Your bedroom temperature should be between 60 degrees Fahrenheit and 67 degrees Fahrenheit (15.5 degrees Celsius to 19.44 degrees Celsius) for optimal snoozing, not some experts.

ALSO READ: Oxford University Scientists Have Found The Reason Behind The Need To Sleep

Better Sleep

As per a 2012 study published in the Journal of Physiological Anthropology, when your body is cooled down, it also helps you sleep better. The quality of sleep significantly improves. Thus, sleeping naked is one of the many ways to achieve the desired temperature.

Good For Skin And Hygiene

A 2017 study published in journal Women's Health, titled Role of female intimate hygiene in vulvovaginal health: Global hygiene practices and product usage, cited the Royal College of General Practitioners guide on care of vulvar skin, and noted that sleeping without underwear allows better airflow, reduces moistures and prevents any potential yeast or bacterial infections.

ALSO READ: Do Feminine Hygiene Products Actually Cause Vaginal Infection?

Intimate skin is prone to have moisture trapped, and removing clothes can help your skin breathe. Since studies have proven that a lower body temperature allows you to have a better sleep quality, further studies, including a 2018 published in Journal of Applied Physiology notes that "adequate sleep" can also help you skin heal from small wound.

Improves Relationship

As per a 2015 study published in the Frontiers in Psychology, skin-to-skin contact between adults stimulates the release of oxytocin, which can play an important role in building attachments, and enhance the feeling of safety. It also thus help you sleep better as you feel less stressed and more in connect with your partner.

Great For Your Self Esteem

A 2021 study published in Journal of Sex Research found that times spent naked helps build body appreciation. This also helps one embrace themselves and self-love. Thus going to sleep naked extends the time you spend naked, and helps you boost your self esteem.

Helpful For Male Fertility

A 2018 study published in the journal of Human Reproduction also noted that sleeping naked is a good way to keep testicles cool and maintain an optimal temperature for sperm health.

The study of 656 men suggested a link between men who wore tight underwear with a low sperm count. The breezier the underwear was, the higher sperm concentration and total sperm count was in the men.

We have all been there, done that. Reaching out to Google every time we face slight discomfort sneezing, convinced that we have some serious disease. While not every ache or tickle means an emergency, some symptoms really do need urgent attention. According to ER doctors, there are a handful of red flags you should never brush off.

Here are six warning signs you should pay attention to immediately.

1. Chest Pain That Feels Super Heavy

We have all had heartburn after a cheesy pizza, but chest pain is not something to gamble with. Reports say crushing, pressure-like chest pain that radiates to your arm, jaw, or back is a huge red flag for a heart attack. Sometimes it comes with sweating, shortness of breath, or nausea. Even if you are young and otherwise healthy, do not assume it is just gas or stress. When in doubt, get checked out; it is always better to be told it is heartburn than to ignore a heart attack.

2. The Worst Headache of Your Life

Sure, headaches are common, but if you suddenly feel like someone is hammering your skull with no mercy, do not tough it out. According to the reports, a sudden, severe headache, especially if it is different from your usual migraines, could signal a brain aneurysm, bleeding, or other neurological emergency. Pair that with vision changes, weakness, or slurred speech, and you should be calling for help immediately.

3. Unexplained Shortness of Breath

Running up the stairs and wheezing like a deflating balloon is one thing. But struggling to breathe at rest or without any exertion? That is a whole different story. Experts say unexplained shortness of breath could point to conditions like blood clots in the lungs, asthma attacks, pneumonia, or even heart problems. If your chest feels tight, you are gasping for air, or your lips are turning blue, it is not something to “walk off”.

4. Sudden Weakness or Numbness in One Side of the Body

If you are holding something, and suddenly it slips right out of your hand because your arm has no feeling. Or half your face feels like it is melting. These are classic stroke symptoms, and ER doctors stress that time is everything. The quicker you get treatment, the higher the chances of recovery. Remember the acronym FAST: Face drooping, Arm weakness, Speech difficulty, Time to call emergency services. Do not wait it out hoping it will pass.

5. Uncontrolled Bleeding

A paper cut? No big deal. A deep cut that refuses to stop bleeding after 10 minutes of firm pressure? That is a medical emergency. According to the reports, that uncontrolled bleeding can mean a damaged artery or an underlying clotting disorder. If you are soaking through bandages or the blood will not stop, it is not something to ignore. Plus, losing too much blood too quickly can lead to shock and nobody wants to faint in their bathroom.

6. Severe Abdominal Pain That Comes Out of Nowhere

Stomach aches are often brushed off as bad food choices. But if you suddenly develop intense abdominal pain that does not go away, reports suggest it could be something much more serious, like appendicitis, gallstones, a perforated ulcer, or even an intestinal blockage. The kind of pain where you cannot stand up straight or move without wincing is not the “sleep it off” kind. Trust your gut, literally, and get checked.

Listen to Your Body’s Alarm Bells

A team of researchers from Kyoto University, Japan, has uncovered hidden immune “hubs” that appear to play a critical role in driving joint damage in patients with rheumatoid arthritis (RA).

The breakthrough, published in Science Immunology, sheds light on why inflammation persists in many patients despite existing treatments and may pave the way for new therapies.

Understanding Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease that affects millions worldwide, causing painful swelling, stiffness, and damage in the joints. It occurs when the body’s immune system mistakenly attacks its own tissues.

While medications such as disease-modifying anti-rheumatic drugs (DMARDs) and biologics have improved outcomes, nearly one in three patients continues to respond poorly to current therapies. This new study provides an explanation for that treatment resistance.

Discovery of Immune Hubs

The Japanese team focused on a subset of immune cells known as peripheral helper T cells (Tph cells). Researchers discovered that Tph cells exist in two distinct forms: stem-like Tph cells and effector Tph cells.

The stem-like Tph cells were found residing inside small immune hubs known as tertiary lymphoid structures within inflamed joints. Inside these hubs, the stem-like cells multiply and activate B cells, which are responsible for producing antibodies.

Some of these stem-like Tph cells eventually mature into effector Tph cells, which leave the hubs and contribute directly to joint inflammation by interacting with other immune cells such as macrophages and killer T cells. This continuous supply of effector cells could be the reason inflammation continues in patients even after treatment.

A New Therapeutic Target

By pinpointing the root of the problem, the scientists believe treatment strategies could shift toward targeting these stem-like Tph cells.

“Because stem-like Tph cells can both self-renew and differentiate, they may represent a root cause of the disease,” said lead researcher Yuki Masuo of Kyoto University. Neutralizing or limiting the activity of these cells at their source could potentially reduce the cycle of inflammation and slow down joint damage.

Advanced Techniques Revealed the Mechanism

The team reached these findings using a cutting-edge approach called multi-omics, which combines multiple layers of biological data.

By analyzing immune cells from both inflamed joint tissues and blood samples of RA patients, they created a comprehensive picture of how Tph cells behave. The results showed that stem-like Tph cells predominantly live inside immune hubs where they maintain close contact with B cells.

To confirm their theory, researchers recreated the environment in the lab by growing stem-like Tph cells and B cells together. They found that this interaction not only helped Tph cells transform into effector cells but also activated B cells, further fueling the immune response.

Why This Matters

The study marks an important step in understanding why rheumatoid arthritis is so difficult to treat in some patients. By revealing the role of immune hubs, it provides a more detailed map of how chronic inflammation is sustained in joints. For patients who struggle with current medications, these insights could one day translate into therapies that are more precise and effective.