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Canada’s leading drug regulator is facing a growing wave of concern over the popular diabetes and weight-loss medication Ozempic, after thousands of reports of adverse effects, some of them being severe, were recorded nationwide.
Health Canada confirmed it has received 11,707 individual reports of adverse reactions linked to drugs containing semaglutide, including Ozempic, Rybelsus, and Wegovy, since their introduction to the Canadian market seven years ago.
The agency has collected 2,706 separate reports detailing these side effects, about half coming from health professionals and half from patients, according to data obtained by Le Journal de Montréal.
Also Read: World Suicide Prevention Day 2025: Theme, History, And Significance
The reported issues range from relatively mild gastrointestinal discomfort to severe events such as poisoning, vision loss, and psychiatric disorders. Gastrointestinal complaints alone account for one-third of the reports — highlighting how common nausea, vomiting, and constipation are among users.
For patients like Liliana Mejia, the experience was devastating.
“It was horrible,” she told Le Journal. “Everything made me want to vomit, my vision was blurred, [I was] tired and constipated for 10 days.”
She stopped using the drug after a little over a year but says she wishes she had been warned about the potential impact earlier. “I don’t think we talk about it enough,” Mejia added.
Her story mirrors that of many Canadians now speaking out about their struggles.
Ozempic was originally designed as a treatment for type 2 diabetes but has skyrocketed in popularity due to its ability to suppress appetite, leading to rapid weight loss.
“It’s a powerful and effective drug that has many benefits, but also side effects that need to be managed,” explained Dr. Rémi Rabasa-Lhoret, endocrinologist and researcher, in comments to Le Journal.
He emphasized that the reports do not necessarily prove a direct cause-and-effect relationship between Ozempic and the complications, but said that listening to patients is crucial. “It requires proper medical monitoring,” he noted, stressing that it should not be used casually or without supervision.
Among the most worrying findings are the psychiatric problems reported by patients, 470 cases have been logged so far. Dr. Rabasa-Lhoret said he has seen patients spiral into eating disorders such as anorexia due to overuse of the drug.
He also pointed to the unprecedented demand for Ozempic, comparing the craze to the hype around Viagra when it first launched. “Many people have started prescribing it without providing proper support to patients,” he lamented, adding that the rise of online pharmacies has made it dangerously easy to obtain the drug without adequate oversight.
One of the most troubling side effects being investigated is non-arteritic anterior ischemic optic neuropathy (NAION), a rare condition that can lead to permanent vision loss.
Jacques Pépin, 69, of Repentigny, Quebec, believes Ozempic played a role in the two strokes he suffered in his eyes over the past year.
“I wouldn’t have taken it if I had known,” Pépin told Le Journal.
He has now lost much of his sight and says he can no longer drive, read, or enjoy his favorite hobby — building model airplanes. “I break glasses, I have no balance,” he said, describing how the vision loss has upended his life.
Health Canada has logged 10 cases of NAION and is currently “reviewing relevant preliminary information on the potential risk.” Novo Nordisk, the drug’s manufacturer, denies a causal link, though its European labels are being updated to include NAION as a potential adverse reaction.
Despite the concerning data, experts caution against panic. Sherbrooke endocrinologist Dr. André Carpentier told Le Journal that while the list of side effects can seem alarming, the drug’s benefits, from controlling diabetes to protecting heart and kidney health, are significant and must be weighed carefully against the risks.
“The link with Ozempic is difficult to establish beyond doubt,” Dr. Carpentier said, noting that certain complications, like sudden drops in blood sugar, can themselves trigger issues like vision problems.
Health Canada continues to collect and analyze data, and experts stress that the key is proper prescription, patient education, and close monitoring. For patients like Mejia and Pépin, however, the damage is already done, and their stories are sparking calls for more transparency about what users can expect before starting these medications.
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Delhi pollution continues to worse, while yesterday their was a brief respite when the air quality index (AQI) levels were reported under the 'poor' category, and the AQI dropped to 269 at 7am on November 30. However, today, on December 1, the AQI at several stations crossed 300.
As per the Central Pollution Control Board (CPCB), Anand Vihar recorded an AQI of 325, ITO at 325, Rohini at 341, Bawana at 339, RK Puram at 336, Vivek Vihar at 321, Shadipur at 324, and Pusa at 322.
The toxic air in Delhi has spared no one, but the worst affected are children. On a recent weekday morning in Noida, a suburb near Delhi, BBC reported that at a crowded children’s clinic parents waited anxiously with little ones who were coughing, wheezing or struggling to breathe.
Most families said their children started falling sick in October, right when the capital’s air quality slipped into the hazardous range. This is a yearly pattern across northern India. A mix of slow winds, industrial fumes, vehicle emissions, dropping temperatures and the burning of crop residue creates a thick layer of pollution that settles over the region.
Since last month, Delhi’s Air Quality Index has mostly stayed between 300 and 400. These levels are over 20 times higher than what the World Health Organization (WHO) considers safe. Readings this high affect everyone, but young children and older adults are the most vulnerable.
Hospitals across the city have been overwhelmed with children suffering from pollution-related illnesses. Dr Shishir Bhatnagar, who heads the clinic in Noida, told BBC the number of cases has jumped sharply. He explained that young children are especially at risk because their immunity is still developing. He usually sees about 20 to 30 percent of cases linked to pollution, but that number doubles during the winter smog.
Although authorities often introduce emergency measures like halting construction or restricting vehicles, the situation has barely improved. Even an attempt at cloud seeding this year failed to bring relief, leaving millions worried about their families’ health.
For some parents, the fear is constant. BBC reports that Khushboo Bharti remembers rushing her one-year-old daughter to the hospital after a severe coughing fit left the baby vomiting and struggling to stay alert. The toddler later needed oxygen and was diagnosed with pneumonia. Other parents share similar worries, wondering whether the polluted air might cause lasting harm.
Research has repeatedly shown that prolonged exposure to polluted air can impair lung development, weaken immunity and even affect brain health. A recent study from the University of Cambridge linked certain pollutants to higher risks of dementia later in life.
While schools have postponed outdoor activities and moved younger classes online, these precautions mainly help families who have access to resources. For children living in crowded homes or near busy roads, the daily exposure is far worse. Doctors urge parents to keep children indoors when possible and use N95 masks, but many families find this unsustainable.
Parents say they feel helpless. They know children need space to play and fresh air to grow, yet every winter forces them to choose safety over normal childhood experiences.
As per CPCB standards, here's how you can read AQI:
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Aids Day, a day that focuses on raising awareness on a disease that effects 40.8 million lives. In 2024 alone, 630,000 people died from AIDS-related deaths. What really is AIDS? It stands for acquired immunodeficiency syndrome, which is an advanced stage of HIV, caused by the human immunodeficiency virus. It damages the immune system so that the body is less able to fight infections and diseases.
Thus, every year, on December 1, World AIDS Day is observed to increase awareness on the same, provide support to people living with it and remember those who have lost their lives to the illness.
This year, the theme for Aids Day is "Rethink, Rebuild, and Rise".
The International AIDS Society (IAS) wants to create a simple message through the theme that it is important for everyone to connect and work against HIV. This is an urge to everyone from local activists to scientists, to governments, and to the global organization.
The world’s fight against HIV is entering a critical phase. Hard-won progress is under threat as political tensions grow and funding becomes uncertain. This year’s theme, “Rethink. Rebuild. Rise.” is a powerful reminder that the global community must stay united, resilient and forward-thinking to meet the challenges ahead.
Rethink calls for stronger, long-term financial planning. It urges countries to invest more of their own resources instead of relying mainly on international support.
Rebuild highlights the need to strengthen health systems, protect scientific research and support civil society groups. It also emphasizes grounding every decision in solid evidence and pushing back against misinformation.
Rise encourages the world to move ahead with a fully funded, people-centered strategy that safeguards past achievements and brings us closer to ending AIDS as a public health threat by 2030.
The United Nations notes that in 2025, funding crisis is threatening the progress made in the prevention of the illness. This is why this day is a reminder for more people to connect, initiate community services that are vital for the marginalized population who are often deprioritized while the rise in punitive law criminalizes same sex relationships, gender identity, and drug use that amplifies the crisis, and makes HIV-AIDS services inaccessible.
The global response to AIDS has been shaken in recent months, and much more work is needed to meet the Sustainable Development Goal of ending AIDS by 2030. The crisis is far from over, and in today’s challenging environment, a fresh, transformative strategy is essential to reduce risks and stay on track.
The day was first observed in 1988 when the World Health Organization (WHO) and the United Nations first launched it to spread awareness about HIV/AIDS, erase misconception, and build empathy for people living with AIDS. This day reminds people around the world that AIDS is not only a health problem but also a social and humanitarian issue for which everyone should work together.
The prevention of AIDS starts from the restriction and complete stoppage of HIV. While there is no vaccine or permanent cure yet, there are ways to prevent AIDS:
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Vaccine safety, a debate the Trump administration just cannot let go. Once again, the same debate is stirring up, and this time an internal Food and Drug Administration memo that The New York Times obtained has linked death of at least 10 children to the COVID vaccine. While the document has not been released publicly, it has already caused controversy and prompted talk of tighter regulations.
The New York Times however reports that the memo did not include essential such as the ages of the affected children, any underlying health conditions, or how the agency reached its conclusions. It also did not identify which manufacturers’ vaccines were involved. Since the findings have not been published in a peer-reviewed journal, many critics of Health Secretary Robert F. Kennedy Jr. have raised concerns about the accuracy and timing of the claims. Kennedy has long questioned the safety of Covid shots, even as scientific consensus maintains that vaccines are safe and have saved countless lives.
Dr Vinay Prasad, who is the head of FDA's vaccine division wrote the memo based on the findings of a review of reports that suggested that the deaths were linked to myocarditis, which is a rare inflammation of the heart muscle.
But, what does the science say? Scientists have studied the connection between Covid vaccines and myocarditis for years, especially among teenage boys and young men. Most studies have shown that the condition is rare and usually resolves quickly.
Even so, Dr Prasad wrote to staff that the memo marked the first time the FDA would acknowledge that Covid vaccines may have played a role in the deaths of American children. He indicated that he would propose several new oversight measures. It is unclear whether the White House had been briefed on these plans or how closely officials would follow them. When The New York Times reached out to Department of Health and Human Services for a comment, the request was declined.
This memo comes at the time when the administration has already taken a more cautious stance on vaccines. Kennedy's team has already introduced new limits on who can or cannot receive COVID shots. The shot has now been restricted to people over 65 and younger individuals with medical vulnerabilities. Officials have also called for renewed studies on long-established vaccines that have been considered safe for decades.
Public health experts from previous administrations have warned that casting doubt on vaccines could have serious consequences. Covid has killed more than a million Americans, including about 2,100 children. Experts note that many more lives were saved because vaccines became widely available.
The memo appeared just before a significant upcoming meeting of the CDC’s vaccine committee, which now includes members known for supporting the medical freedom movement. Michael Osterholm, an infectious disease specialist, said the timing did not seem accidental and called the release “irresponsible.”
Other experts expressed concern that the memo lacked important context. Dr. Paul Offit of the Children’s Hospital of Philadelphia pointed out that myocarditis from Covid infection itself has been far more severe than the rare cases linked to vaccines.
Dr. Prasad also criticized previous mandates for school and workplace vaccination, claiming they pressured people into receiving shots that might pose risks. His memo ended by addressing internal disagreements within the agency and outlining how staff should resign if they oppose the new direction.
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