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In what is being considered a huge leap in the field of reproductive health, a baby girl has been born to a mother with a donated womb in the UK. Grace Davidson, 36, was born with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a rare condition in which the uterus is absent or underdeveloped, but the ovaries function normally. In 2023, she underwent the UK’s first successful womb transplant, receiving the uterus from her sister, Amy Purdie.
Two years after the groundbreaking transplant, Grace gave birth to her daughter, Amy, in February 2025. The name honours the woman who made the pregnancy possible. The new mother described the moment she first held Amy, who weighed just over two kilos (4.5 pounds), as "incredible" and "surreal." "It was quite overwhelming because we'd never really let ourselves imagine what it would be like for her to be here," she said.
Grace first spoke to the BBC in 2018 about her hopes of becoming a mother through a womb transplant. Although her mother was initially considered as a donor, her uterus was found to be unsuitable. By 2019, Grace's sister Amy—already a mother of two—was being evaluated as a donor. After pre-surgery counselling and IVF treatment, Grace had several embryos stored.
The transplant, delayed due to the pandemic, was finally performed in February 2023. A surgical team of over 30 medics took 17 hours to remove Amy’s womb and successfully transplant it into Grace. Within two weeks, Grace experienced her first period and later conceived through IVF on the first attempt.
Grace described feeling her baby's first kick as "incredible" and the entire pregnancy as "really special." Baby Amy was born via Caesarean section at Queen Charlotte’s and Chelsea Hospital on 27 February. "It was an incredible moment, full of joy," said surgeon Isabel Quiroga, who led the transplant team.
The couple hopes to have a second child before the donated womb is removed. This will allow Grace to stop taking immunosuppressant drugs, which prevent organ rejection but can increase cancer risk if taken long-term. Surgeon Quiroga assured that the risk should return to baseline once the uterus is removed.
Professor Richard Smith, a gynaecological surgeon at Imperial College Healthcare and head of Womb Transplant UK, called Amy's birth "astonishing and incredibly moving." He said around 15,000 women in the UK of childbearing age lack a functioning uterus, including about 5,000 born without one. His charity covered NHS costs for Grace’s transplant, with medical professionals donating their time.
Currently, 10 women are in fertility treatment or have embryos stored. Each transplant costs approximately £30,000, and the charity is funding two more. The clinical trial aims to complete 15 transplants—five from living donors and 10 from deceased ones. For Grace, the experience has deepened her bond with her sister. "It was incredibly difficult to let her do that for me," she said. "It's a huge act of sisterly love."
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President Trump recently underwent “advanced imaging” of his abdomen and cardiovascular system as a preventive step, according to the White House. This update came on Monday, a day after the president admitted to reporters that he wasn’t sure which areas the MRI had covered during his October physical at Walter Reed National Military Medical Center. On Sunday, he mentioned that the scan had nothing to do with his brain and that the results were “perfect,” though he still did not know what had been examined. The White House has now shared a detailed memo offering a clearer picture of the president’s health status.
US President Donald Trump is said to be in “excellent overall health” after completing a “comprehensive executive physical,” according to his White House physician. Captain Sean Barbabella issued a memo on Monday noting that the advanced imaging performed on the 79-year-old president’s heart and abdomen showed “perfectly normal” findings.
As per BBC, he explained that the MRI was carried out during Trump’s October physical because men in his age range benefit from a closer review of their cardiovascular and abdominal health. The update arrives as Democrats, including Minnesota Governor Tim Walz, have continued to ask for the scan results, pointing to concerns about the president’s age as he enters another term.
At Monday’s briefing, White House Press Secretary Karoline Leavitt read the physician’s memo in full. She said the administration wanted to be open about the findings. “The president said last night that the results would be released, and they are now available,” she added.
According to the memo shared by the White House, Barbabella reported no signs of arterial narrowing that would restrict blood flow, nor any irregularities in the president’s heart or major blood vessels. He wrote that Trump’s cardiovascular system “shows excellent health.” The doctor, a US Navy emergency physician with service experience in Iraq and Afghanistan, also said the abdominal imaging revealed that “everything evaluated is functioning within normal limits with no acute or chronic concerns.” He described the MRI as a routine part of an “executive physical” for someone Trump’s age. Earlier, the White House had avoided commenting on why an MRI was included in the October exam or specifying which part of the body had been scanned.
For context, Trump completed his annual physical in April. When he spoke in October, he mentioned that he received an MRI at Walter Reed during a visit that the White House said fell under his “routine yearly checkup.” At the time, Trump stated the results were “perfect.” In the memo, Barbabella said the MRI was done as a preventive measure “to identify issues early, confirm overall health, and ensure he maintains long-term vitality and function.”
Donald Trump has also been diagnosed with chronic venous insufficiency (CVI), a condition in which veins in the legs struggle to push blood back toward the heart. The White House confirmed the diagnosis after he sought medical advice for mild ankle swelling. CVI is fairly common, especially among older adults, and can lead to symptoms such as swelling, discomfort, and aching in the legs.
According to the Mayo Clinic, chronic venous insufficiency occurs when the valves inside the leg veins, which normally stop blood from flowing backward, become weakened or damaged. This allows blood to collect in the legs and increases pressure within the veins. Typical symptoms include swelling, heaviness or aching in the legs, and changes in skin colour. The condition is more likely in people who are older, have a family history of CVI, remain seated or standing for long periods, or have a higher body weight.
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Delhi's pollution continues to worsen, and every day, there is new data on its AQI levels, suggesting the conditions Delhiites are living in, unable to breathe, go out, and much more. In fact, 60.3% of Delhi-NCR residents have sought pollution-related medical assistance last year, showed a survey by SmyttenPulseAI. The number is severe and points towards a healthcare crisis in the making.
The survey also showed that 80% of residents reported experiencing persistent health issues, which included chronic cough, debilitating fatigue, and respiratory irritation due to polluted air.
It was a study that surveyed 4,000 residents across Delhi, Gurugram, Noida, Ghaziabad, and Faridabad and found that 76.4% of respondents have drastically reduced outdoor time. This means they have turned their homes into the only place of solace, often like virtual prisons for families to hide from the toxic air outside.
The survey also found that 79.8% of the residents are either reconsidering their stay or have already left, with 33.6% planning their departure, while 31% are actively considering relocating, and 15.2% have already relocated.
Why the relocation? s Dr Rahul Chawla, a neurologist trained at AIIMS, who, on his Instagram, posted a video where he suggested that if people can afford, and their profession allows, they must leave Delhi for a few weeks. “Because this city has become a gas chamber,” he warned.
The survey is a reflection of the same thought, with 37% residents who have already taken concrete steps of visiting properties in nearby cities. They have enquired for schools, or have made family decisions about leaving. The preferred destination for most are: hilly areas, small towns with fewer factories, and anywhere outside Delhi-NCR that does not mean to continuous keep an eye on AQI monitor app while breathing, as reported by NDTV.
The report said pollution has added a heavy economic burden on middle-class families, with 85.3 per cent noticing higher household expenses because of it. Among them, 41.6 per cent said the financial strain has been significant.
Dr Chawla suggested that one should stay indoors as much as possible. "You can open the windows and doors only between 1 and 3pm in the day, when you feel that the sun is bright, so that the house gets proper ventilation," he said.
Why 1pm to 3pm is the only time he suggests to have exposure with air? As per a 2023 study by an air filter brand, Delhi's air pollution peaked at 9AM and gradually improved as the day progressed. On an average, Delhi sees roughly as half as much PM2.5 by 5PM. Similarly, in Kolkata, the pollution peaks at 8am and is lowered by 4PM. This is why the safest time to have any sort of air exposure is in the afternoon. Pollution levels also tend to be slightly lower in the afternoon because it is when the sun is at its peak. This heats the ground and causes warm air to rise and mix with atmosphere. This helps disperse pollutants.
He also advised against cleaning inside the house using a dry cloth, and suggested wet cloth to be in use, so that dust does not rise. "Please do not light up things inside the house like burning dhoop (incense for worship), agarbatti (incense sticks), or anything else that causes excessive smoke,” he said.
“If there are elderly people at home, do not let them go for morning walks or evening walks, and if there are children, do not let them play in the park. Exercise at home. You can go up and down the stairs. You can do yoga. If you have a treadmill or a stationary bike at home, you can exercise with it. You can do weightlifting,” he said. However, he suggested that if going out is absolutely necessary, then one must wear N-95 mask properly before stepping out.
“If you can afford an air purifier, buy one. But keep in mind that the air purifier you are buying should be appropriate for the size of your room,” the neurologist advised.
The neurologist also suggested that if your company permits it, seek work from home option to reduce your exposure from toxic air.
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Ozempic, Wegovy, Saxenda, Trulicity, Mounjaro, all from different brands, with different active ingredient but all are GLP-1-type drugs, which have now been linked with depression, suicidal thoughts, and changes in mood and behavior. As a result, the Therapeutic Goods Administration (TGA), Australia released a safety alert on Monday to update the product warnings of GLP-1-type drugs.
This is to "ensure consistent information regarding the potential risk of suicidal thoughts or behaviours". The alert said, "The updates follow investigations by TGA and other international regulators. Patients taking any of these medicines should tell their health professional if they experience new or worsening depression, suicidal thoughts or any unusual changes in mood or behaviour."
While the TGA noted that not enough evidences were there to conclude the drugs caused such changes however, there is indeed a complex relationship between mental illness and conditions GLP-1 drug treat, that could be associated with suicidal thoughts, which cannot be ignored.
The TGA has issued a separate warning about a possible link between the GLP-1 drug tirzepatide, sold as Mounjaro, and reduced effectiveness of oral contraceptives. The regulator said it cannot rule out the possibility that the medication may interfere with how well oral birth control works. As a precaution, product information for tirzepatide has been updated to include clearer advice for patients who rely on the pill.
According to the TGA, women who are taking tirzepatide should consider switching to a non-oral contraceptive or using an additional barrier method for four weeks after starting the medicine. The same advice applies for four weeks after each time the dose is increased.
The alert also reminded patients that GLP-1 medications should not be used during pregnancy.
GLP-1 drugs have become widely known for helping people manage type 2 diabetes and obesity. They work by copying the action of a natural hormone that slows digestion and helps people stay full for longer. Their popularity has skyrocketed over the past few years, but there has also been ongoing discussion about their potential mental health effects.
Some studies overseas have suggested that people with anxiety or depression might face a higher risk of depression, anxiety or suicidal thoughts when taking these medications.
The US Food and Drug Administration has been reviewing reports of suicidal thoughts among people using GLP-1 drugs. So far, the agency says it has not found evidence that the medications directly cause these thoughts, although it notes that the number of cases is small and it cannot completely rule out a possible risk.
The TGA highlighted similar concerns in its safety update. The agency has received 72 reports of suicidal thoughts from people taking GLP-1 drugs, along with a smaller number of reports involving suicide, attempted suicide or depression-related suicide.
With an estimated half a million Australians now using these medicines, the regulator launched a detailed review and sought advice from the Advisory Committee on Medicines. The committee concluded that the available evidence does not support a clear link between GLP-1 drugs and suicidal or self-harming behaviour. However, it recommended updating product information to ensure consistency and to promote awareness without suggesting a proven causal connection.
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