Ozempic Lawsuit: "This week's study doesn't suggest that GLP-1 cause your eyes to fall out exactly, but, as you will see in a second, it is not that far off," says Dr F Perry Wilson, MD, MSCE, physician, researcher, educator, and writer, at Yale School of Medicine, before he begins to explain what the new study suggests of the side effects.

Weight loss drugs have gained popularity up recently. The popularity is for all the right, and the wrong reasons too. While up recently, we have Wegovy being approved for treating MASH, we also have unheard side effects of the popular drug Ozempic, and not to mention, the cases of pancreatitis reported in the UK, and the ongoing lawsuit on Ozempic.

So, what does this new study add to all this?

Weight Loss Medication And Vision Loss

Two studies, published in JAMA, analyzed how semaglutide, an injection used to treat type 2 diabetes that helps control your blood sugar, and tirzepatide, an antidiabeteic medication, also used to treat type 2 diabetes and for weight loss, administering via injections, which include popular drugs like Ozempic, Wegovy, Mounjaro and Zepbound, impacted eye health in Americans with type 2 diabetes over a 2-year period.

What Did The Study Find?

One of the studies found a modest risk of developing a non-arteritis anterior ischaemic optic neuropathy (NAOIN), which is a rare eye condition that can lead to sudden vision loss due to lack of blood flow. This condition has close links with the consumption of semaglutide and tirzepatide.

Out of more than 159,000 participants with type 2 diabetes, 35 developed NAION, compared to 19 people in the comparison group. The Ohio-based researchers also noted an increased risk of developing "other optic nerve disorders" identified in 93 patients.

The second study found no statistically significant link between GLP-1 drug use and NAION, a rare eye condition, but reported a slight uptick in cases of diabetic retinopathy, a retinal disease that can cause vision loss.

The study observed that individuals with type 2 diabetes who were treated with GLP-1 drugs faced a modestly higher risk of developing diabetic retinopathy. However, researchers emphasized that fewer patients progressed to sight-threatening stages of the disease. They concluded that all patients with type 2 diabetes receiving GLP-1 therapies should undergo regular screening and monitoring for potential eye complications, regardless of whether they already have diabetic retinopathy.

"These findings suggest that all patients with type 2 diabetes treated with GLP-1 RAs, regardless of preexisting diabetic retinopathy, should be regularly screened and monitored for potential complications," the study authors concluded.

What Are The Experts Saying?

As questions continue to mount about the potential connection between GLP-1 weight-loss drugs and vision problems, experts stress that more research is needed before drawing firm conclusions.

Sue Decotiis, M.D., a medical weight-loss doctor in New York City, said she believes additional studies are required to confirm whether the drugs increase the risk of vision loss, pointing to conflicting findings so far.

"NAION is a rare condition of the optic nerve that, although serious, has not really been shown to be increased by these studies," Decotiis, who was not involved in the research, told Fox News Digital. "We need more studies for certain."

She noted that diabetic patients already face a heightened risk of eye disease due to blood flow and nerve damage. "Eye complications are often directly related to the degree or lack thereof of diabetes control," she explained.

According to Decotiis, GLP-1 drugs often help reduce the severity of type 2 diabetes, which can in turn lower the risk of eye disease. These medications have also been shown to reduce cardiovascular risks, such as hypertension, and improve circulation, both of which may benefit eye health.

For patients beginning GLP-1 treatment, she advised proactive monitoring. "We should take precaution with methodical ophthalmic care for diabetics on these drugs," she said. "However, let’s not throw the baby out with the bath water."

Ashley Brissette, M.D., an ophthalmologist in New York City, echoed that perspective, calling NAION an "extremely rare" but serious medical condition. She emphasized that the risk associated with GLP-1 drugs is also “extremely rare, at a risk of about one in 10,000, according to other studies.”

"I think caution with anything is warranted," Brissette told Fox News Digital. "And remember these are associations, not causations, so it's not to say that GLP-1 use causes NAION or worsening retinopathy, but their use is associated with these conditions."

She underscored the importance of thorough eye care: "From an ophthalmologic standpoint, these findings underscore the importance of baseline and follow-up eye examinations for patients starting GLP-1 therapy, especially those with pre-existing retinal or optic nerve risk factors."

Brissette added that while the benefits of GLP-1 drugs in reducing cardiovascular and metabolic risks are “substantial,” patients should be counseled on potential vision-related side effects, and “any sudden visual symptoms should prompt immediate ophthalmic referral.”

When contacted by Fox News Digital, Novo Nordisk, the maker of Ozempic and Wegovy, said it stands by the safety of its medications.

"Patient safety is a top priority for Novo Nordisk, and we take all reports about adverse events from the use of our medicines very seriously. NAION is a very rare eye disease, and it is not an adverse drug reaction for the marketed formulations of semaglutide (Ozempic, Rybelsus and Wegovy) as per the approved labels in the U.S."

The company added: "Novo Nordisk, on its part, has conducted an analysis across randomized controlled clinical trials with GLP-1 receptor agonists, including a blinded ophthalmologist evaluation to confirm NAION diagnoses. Our current assessment is that these data do not suggest a causal relationship between GLP-1 RA use and NAION events."

Wegovy maker Novo Nordisk has ended its legal dispute with the Hims & Hers Health platform, according to a media report.

The two companies are likely to partner and sell the blockbuster obesity drug Wegovy together on the Hims & Hers Health platform, Bloomberg News reported.

Market analysts have expressed surprise on the move, as both Novo and Hims have been previously engaged in legal battle over Wegovy.

“There is no other way to describe the Hims news as both a surprise and an unabashed positive for Hims' stock,” Leerink Partners analyst Michael Cherny was quoted as saying in a note to clients.

A Novo spokesperson said in an emailed statement that the company is "always in conversation with companies that can help improve patient access to FDA-approved medicines".

The Dispute Between Novo and Hims

In February, Novo sued Hims for launching a similar version of its new Wegovy weight-loss pill for $49.

The Danish drugmaker accused Hims of patent infringement on Semaglutide -- the active ingredient behind its best-selling medications Ozempic and Wegovy.

Semaglutide is popularly known for weight loss , but is also effective for diabetes and is used primarily for that.

The US Food and Drug Administration (FDA) had also threatened action against Hims.

Last year, Novo had to end a short-lived agreement to sell Wegovy over Him's marketing tactics and continued sales of copycat versions of Wegovy.

Recently, the FDA has signaled plans to crack down on the proliferation of copycat, or compounded, weight-loss drugs.

Wegovy And Ozempic To Cost Less In 2027

Currently, Wegovy injections and pills cost $1,349.02 a month, whereas Ozempic and Rybelus cost $1,027.51, Novo told PEOPLE.

Individuals with commercial insurance pay $25 a month, whereas those using cash pay between $149 to $499. Patients on Medicare will pay $274 per month.

Late in February, Novo Nordisk announced it would slash the price for all doses:

• The list price of Wegovy injections and the new Wegovy pill will be cut in half
• Ozempic injections will be cut by 35 percent
• The semaglutide tablet Rybelsus will now cost $675 a month

"There are more than 100 million people living with obesity and over 35 million with type 2 diabetes and, and for some, list price has been a real barrier to access and affordability," Jamey Millar, Executive Vice President, US Operations of Novo Nordisk Inc., was quoted as saying to PEOPLE.

Indian Drugmakers Rush For Generic Weight Loss Drugs

Meanwhile, amid the patent expiration of semaglutide, several pharma companies in India are planning big launches of Wegovy's generic versions.

Several leading drugmakers have already secured regulatory approval or recommendations to produce and market generic versions of the weight loss drugs in the country.

Hyderabad-based Dr. Reddy's already applied for a trademark with the brand name Obeda and a logo.

Other companies like Sun Pharma, Zydus Lifesciences, and Nacto Pharma are also entering the rat race of launching multiple generic versions to make the treatment more affordable for patients with obesity and weight-related health risks.

Sun Pharma also announced the plans for "day-one" launches of generic prefilled pens.

The US Food and Drug Administration (FDA)’s Vinay Prasad has once again — for the second time in less than a year — stepped down from his post as director of the agency’s Center for Biologics Evaluation and Research, amid controversies over the review of vaccines and specialty drugs for rare diseases.

Announcing the news to FDA staff in an email late Friday, FDA Commissioner Marty Makary said Prasad would depart at the end of April. Makary added that Prasad would return to his academic position at the University of California, San Francisco (UCSF).

Taking to social media platform X, Makary said that under Prasad’s leadership, his center recorded a record number of approvals in December.

“A year ago, Dr. Prasad came to the FDA to implement four major long-lasting reforms: a 2-to-1 pivotal trial requirement, national priority reviews, a risk-stratified COVID vaccine framework, and the new plausible mechanism framework for ultra-rare diseases, which we launched last week,” Makary said.

The FDA commissioner noted that Prasad “got a tremendous amount accomplished within his one-year sabbatical from UCSF and will be returning to his academic home later next month,” and thanked him “for his service and personal sacrifice in taking time away from his family.”

The FDA is expected to announce Prasad’s successor before his departure.

Who Is Vinay Prasad?

Vinay Prasad is an Indian-origin American hematologist-oncologist and author. He was first appointed as the FDA’s vaccines chief in May 2025.

Prasad, known as a longtime critic of the FDA’s standards for drug reviews, drew controversy for raising the bar for new drug approvals. The move did not sit well with pharmaceutical companies and reportedly dashed the hopes of some patients with rare diseases.

In July, he was removed from his position following disputes with biotechnology executives, patient organisations, and conservative allies of US President Donald Trump. He was later reinstated after Makary and US Health Secretary Robert F. Kennedy Jr. pushed for reconsideration.

What Is The Controversy?

While Prasad, along with Makary, announced several measures to make FDA drug reviews faster and easier for companies, he also imposed new warnings and study requirements for some biotech drugs and vaccines.

This was particularly evident in the case of COVID-19 vaccines, which have been a target of criticism from Kennedy, who was a longtime anti-vaccine activist before joining the Trump administration.

The latest controversy involves the FDA’s interactions with Dutch biopharma company uniQure, which developed an experimental gene therapy for Huntington’s disease that is injected directly into the brain during a surgical procedure.

Huntington’s is a deadly neurological condition affecting about 40,000 Americans, and currently has no cure.

UniQure faced a setback after Prasad’s centre said its earlier studies were insufficient to support a biologics licence application.

During an earnings call earlier this week, the company said the FDA was demanding a new trial involving sham surgery for some patients.

Executives said the request for a sham-controlled trial contradicted earlier FDA guidance. They also questioned whether such an approach would be ethical for patients with Huntington’s disease, which is progressive and ultimately fatal, typically in middle age.

Earlier, Prasad also refused to allow the FDA to review a highly anticipated flu vaccine from Moderna made using mRNA technology.

The rejection of the application -- highly unusual for the FDA -- prompted Moderna to go public with Prasad’s decision and vow to formally challenge it.

A week after the rejection became public, the FDA reversed course and said it would accept the vaccine for review, pending an additional study from the company.

Prasad’s handling of rare-disease therapy applications also drew criticism after the FDA asked Sarepta Therapeutics, a drugmaker developing treatments for Duchenne muscular dystrophy, to pause shipments following reports of patient deaths.

The company initially resisted, wanting to continue distributing treatments for patients who could still walk, but later agreed. The agency, however, reversed the pause just days later.

Duchenne muscular dystrophy affects a small number of boys and young men who typically lose their ability to walk before puberty and often die by around age 30.

Union Health Minister JP Nadda has announced that cervical cancer screenings using Visual Inspection with Acetic Acid (VIA) will now be available at Ayushman Arogya Mandirs and other health facilities for women between 30 and 65 years of age.

"Screening for cervical cancer is now available at 1,81,000 Ayushman Arogya Mandirs, also known as Health and Wellness Centers, across the country as a part of population based screening for early detection and treatment," said Nadda, while addressing a press briefing at the World Health Organization virtually.

Using VIA, a low-cost, point-of-care method, trained health workers will screen women for cervical cancer. Those who test positive will then be referred to higher centers for diagnostic confirmation and further evaluation.

Nadda also shared that the cervical cancer screening in the country has been expanded as part of comprehensive primary healthcare under the National Program for Prevention and Control of Non-Communicable Diseases (NP-NCD).

"Over 86 million women have already been screened for cervical cancer under the program, reflecting India’s sustained commitment to early detection and prevention," Nadda informed.

Despite being highly preventable as well as treatable, cervical cancer is a public health concern in India.

The country loses one women every eight minutes to cervical cancer.

As per the World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus, about 42,000 new cases of cervical cancer is reported annually in India. This underscores the need for preventive measures such as vaccination and early screening.

The WHO Global Strategy to eliminate cervical cancer includes the 90-70-90 targets by 2030 -- vaccinating 90 per cent of girls against HPV, screening 70 percent of women, and ensuring treatment for 90 percent of those diagnosed with cervical disease.

In line with the global strategy to fight cervical cancer, Prime Minister Narendra Modi recently also launched a free HPV vaccination drive that will target health and well being of adolescent girls in the country.

What Is Cervical Cancer?

Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.

When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.

Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).

Symptoms Of Cervical Cancer

Cervical cancer has no symptoms in the early days and therefore, is hard to detect until it has spread. However, the early-stage symptoms include:

• Vaginal bleeding after sex
• Vaginal bleeding post-menopause
• Vaginal bleeding between periods or unusually heavy/long periods
• Watery vaginal discharge with a strong odour or containing blood
• Pelvic pain or pain during intercourse
• Advanced Cervical Cancer Symptoms (when cancer has spread beyond the cervix)
• Painful or difficult bowel movements or rectal bleeding
• Painful or difficult urination or blood in the urine
• Persistent dull backache
• Swelling of the legs
• Pain in the pelvis or lower abdomen

How Can Cervical Cancer Be Prevented?

Cervical cancer is largely preventable and, when detected early, it is highly treatable. The WHO recommends HPV vaccination for girls aged 9 to 14, before they become sexually active, along with regular cervical screening from age 30, or 25 for women living with HIV.

Despite this, unequal access to vaccination, screening and treatment continues to drive higher rates of illness and deaths in regions such as sub-Saharan Africa, Central America and Southeast Asia.