As per the researchers who reported at the 2025 American Society of Clinical Oncology Gastrointestinal Cancers Symposium which was held last week in San Francisco, an experimental blood test can accurately and effectively detect colon cancer. The researchers also emphasized on its detection in middle-aged and senior population. The blood test had an 81% accuracy rate in detection. It was also 90% accurate in ruling out colon cancer among healthy people.

Why Is It The Need Of The Hour?

Such a test is need of the hour because it helps people determine whether they require a screening. While as per the Cancer Screening Guidelines by Age by the American Cancer Society, it is generally recommended for people after 40 to consider colon cancer screening, the reality is far from it. Around 22% of people eligible for colon screening have never received it, in some states the percentage is higher than 40%.

The study is published by Aasma Shaukat of the NYU Grossman School of Medicine, titled Performance of a blood-based test for colorectal cancer screening adjusted to the US census age and sex distribution.

READ: Calcium In One Glass Of Milk Daily Could Prevent Bowel Cancer

What Tests One Should Get For Colon Cancer?

The standard test for colon cancer is colonoscopy. However for this, patients must often undergo unpleasant bowel preparation and then be anesthetized during the procedure. Fecal blood tests are also used to screen for colon cancer, annually.

A colonoscopy is a medical procedure that allows a doctor to examine the inside of the colon and rectum. A doctor in this process inserts a colonoscope with a long, flexible tube with a camera and light into the rectum and colon and the camera sends images to a monitor to provide magnified view of the colon lining.

How Can You Prepare For A Colonoscopy?

Usually, one needs to take a laxative to empty their bowels and also follow a special diet a day before the procedure. This would be communicated by your GP or the doctor you have an appointment with. People are recommended to also avoid red liquids, which may be mistaken for blood during the procedure. Before the procedure starts, inform your doctor for any medication you are prescribed, and or any existing health issues like diabetes, heart problem, or high blood pressure.

“Until now, we have only had stool-based tests and colonoscopy or sigmoidoscopy. A blood test has the potential for improving colorectal cancer screening rates,” Shaukat said.

ALSO READ: What Are Colorectal Cancers? Is It Different From Colon Cancer?

How Was The Study Conducted?

The researchers tried the experimental blood test on more than 40,000 people aged between 45 to 85 at 200 sites across the United States. These people had their blood drawn and then underwent a standard colonoscopy. Researchers then compared the results to see how well the blood tests stacked up against colonoscopy.

What Did The Study Find?

The blood-based screening test met all primary endpoints, with a sensitivity for colorectal cancer of 79.2% and a specificity for advanced colorectal neoplasia of 91.5%.

Shaukat also noted that this analysis provided a "snapshot of how the test would perform in the US population" and that the sensitivity for colorectal cancer and advanced precursor lesions was "lower than expected and will continue to be optimized in future research development."

During times of crisis or heightened emotions, we seek our elders for some clarity as well as for someone who will keep a cool head during these times. We are always told that wisdom and ways to handle difficult situations are things we gain as we age and a new study shows that this fact holds a lot of truth. We all remember our grandparents and how sweet, calm and patient they were, no matter how many times we messed up or did things that would anger our parents.

A new study suggests this isn't just a personality trait but a skill that improves with age, particularly for women. Research published in the journal Menopause indicates that as women age, especially from middle age onward, their ability to manage anger significantly improves.

Anger Intensifies, Expression Softens

Here's the interesting part: this doesn't mean older women feel less angry. In fact, the study, which looked at information from 271 women over many years, found that they actually reported feeling angrier more often and more strongly as they aged. But here's the key difference: they were much less likely to show their anger outwardly or act in a hostile way. So, even though the feeling of anger might be stronger, their ability to control how they react becomes much better. They might feel it, but they don't necessarily let it burst out.

Why the Shift?

So, why does this happen? Researchers have a couple of ideas. One thought is that as women reach middle age and go through menopause, they often feel a stronger sense of "generativity." This basically means they feel a deep need to help and care for others, especially younger generations, and to make a positive impact on the world. This feeling might help them become more emotionally mature and integrated.

Another idea is that women might become more strategic about how they express their anger. Instead of just lashing out, they might choose more positive and constructive ways to deal with their feelings, which can actually help improve their relationships. When women use anger in these more positive ways, they often feel more empowered and have better self-esteem.

Knowing When Your Anger Is A Problem

According to the American Psychological Association, anger management aims to lessen both the strong feelings of anger you experience and the physical reactions it triggers in your body. While you can't always avoid or change the people or situations that make you angry, you can learn to control how you react.

There are tests that can measure how intense your anger is, how often you get angry, and how well you handle it. However, if you're struggling with anger, you probably already know it. If your actions feel out of control or frightening to you, it might be time to seek help in finding healthier ways to deal with this powerful emotion.

What Does This Study Imply?

Experts point out that the changes women experience during menopause can really affect their mental well-being, both in their personal lives and at work. She explains that shifts in hormones during times like postpartum (after childbirth), during monthly periods, and around menopause can lead to strong mood swings, including feelings of anger and hostility. She stresses that if women are informed about these possible mood changes and get help managing their symptoms, it can make a huge difference in their overall quality of life and health. The study's authors also believe we need more research to understand women's anger in everyday situations, which can give us even more helpful tips on managing emotions and anger.

In 1998, a mysterious and deadly illness emerged among pig farmers in Malaysia, later identified as the Nipah virus (NiV), a bat-borne zoonotic pathogen from the Henipavirus genus. It caused severe respiratory illness and encephalitis, claiming over 100 lives and decimating the pig farming industry.

The virus reappeared in Singapore in 1999. Over time, it was clear that the outbreaks weren’t isolated events. NiV had entrenched itself across regions with certain ecological and socio-cultural conditions, particularly in South and Southeast Asia.

Today, NiV is considered one of the World Health Organization's priority diseases for research and development due to its high case fatality rate (up to 100% in some outbreaks), human-to-human transmissibility, and pandemic potential.

25 Years, 754 Cases, 435 Deaths

As of May 2024, there have been 754 confirmed human Nipah cases reported across five countries—Malaysia, Singapore, Bangladesh, India, and the Philippines—with 435 deaths, averaging a staggering case fatality rate (CFR) of 58%

.

The most affected countries are:

• Bangladesh: 341 cases, 241 deaths (CFR 71%)
• India: 102 cases, 74 deaths (CFR 73%)
• Malaysia: 283 cases, 109 deaths (CFR 39%)
• Philippines: 17 cases, 9 deaths (CFR 53%)
• Singapore: 11 cases, 1 death (CFR 9%)

Unlike Malaysia and the Philippines, where the virus spread through intermediate hosts like pigs or horses, cases in Bangladesh and India have been directly linked to bat-to-human transmission—primarily through the consumption of raw date palm sap contaminated by infected fruit bats.

Why Does Nipah Still Exist?

Fruit Bats Are Permanent Reservoirs

Nipah virus resides in Pteropus fruit bats, which are widely distributed across Asia, the Pacific Islands, and even parts of Africa. These bats are natural carriers and do not show symptoms of the disease, making them difficult to monitor or control. NiV RNA and antibodies have been found in bats in at least 15 countries, including India, Cambodia, Indonesia, and Ghana.

Human Habits Enable Spillover

In regions like Bangladesh, seasonal practices such as collecting fresh date palm sap—a delicacy also consumed raw—provide a direct interface between humans and bat secretions. The virus can contaminate sap through bat saliva or urine.

Moreover, in the Philippines, outbreaks were traced to the butchering and consumption of sick horses. These recurring interactions with potential intermediary hosts keep the door open for viral spillover.

Human-to-Human Transmission

Although not as contagious as influenza or COVID-19, human-to-human transmission of NiV has been confirmed in Bangladesh and India. Some outbreaks have shown vertical transmission (mother to child) and transmission among caregivers and family members.

This capability increases the risk of community spread, particularly in regions with delayed detection or inadequate isolation infrastructure.

No Vaccine, No Cure

Despite being on the global priority pathogen list, there is no licensed vaccine or specific treatment for Nipah. Management remains supportive, relying on early diagnosis and intensive care. In resource-constrained regions, especially rural South Asia, this becomes a daunting challenge.

Bangladesh and India: The Epicenters of Ongoing Risk

Since 2001, both Bangladesh and India have reported almost every year either isolated or clustered cases of Nipah virus, particularly in Kerala and West Bengal (India) and multiple districts in Bangladesh.

Notably, 2023 saw Bangladesh’s highest ever reported NiV cases and deaths. In 2024, the country reported two cases—both of which were fatal, marking a 100% CFR for the year

.

Efforts in both countries have been ramped up. Surveillance now includes:

• Testing date palm sap for contamination
• Educating communities to avoid raw consumption
• Quarantining suspected cases
• Expanding diagnostic labs and outbreak response teams

Still, challenges remain due to cultural habits, lack of rapid testing in rural areas, and public fatigue around health advisories.

The Risk of a Wider Spread

Though human NiV cases have so far been reported only in Asia, the potential for global spread exists. Several factors fuel this concern:

Genetic adaptability: The virus has shown potential for genetic reassortment, raising fears of a more transmissible strain.

Broad geographic distribution: NiV-carrying bats exist far beyond the current outbreak zones.

Environmental change: Deforestation, land-use changes, and climate shifts are bringing bats closer to human habitats.

Global travel and trade: A delayed diagnosis in one international traveler could enable the virus to spread outside endemic zones.

What Needs to Be Done?

A Global “One Health” Approach

The study by Sakirul Khan et al. emphasizes the urgent need for multisectoral collaboration—involving human health, veterinary, and environmental sciences—to monitor and prevent outbreaks

. A “One World, One Health” model is key.

Steps must include:

• Strengthening high-containment laboratories in risk zones
• Continuous monitoring of viral genetic changes
• Developing and testing vaccines and antiviral therapies
• Investing in bat ecology research and habitat protection
• Community engagement and behavioral change strategies

Known for her iconic role as Claire in the Modern Family, Julie Bowen who is a versatile American actress, recently spoke about the rare heart condition she's was diagnosed with at 29.

Speaking about it on the first episode of 'Inside of You' with host Micheal Rosenbaum, Julie revealed her condition 'shy sinus syndrome' that caused her to have a low resting heart rate. She also explained how, due to the condition, she also has had a pacemaker put in place.

Lifelong Low Heart Rate and a Surprising Diagnosis

Bowen explained that she has always had a remarkably low resting heart rate, even around 30 beats per minute at times, a significant deviation from the normal range of 60 to 100 beats per minute for women. This was due to sick sinus syndrome, a heart rhythm disorder exacerbated in her case by hypervagotonia, an overactive vagus nerve. Despite being a competitive runner, her low heart rate was a constant, though initially unexplained, characteristic.

The John Hopkins Medicine explains that sick sinus syndrome (SSS) occurs when your heart's natural pacemaker, the sinoatrial (SA) node in the upper right chamber, becomes damaged and can no longer regulate your heartbeat properly. This damage can result from underlying medical conditions or certain medications, leading to heartbeats that are too slow, too fast, or fluctuate between both extremes.

Recognizing the Symptoms

You might have SSS with no symptoms at all, or only mild ones. However, if symptoms do appear, they can include:

• Dizziness
• Fainting (syncope)
• Shortness of breath, especially with physical activity
• Heart palpitations (a fluttering or pounding sensation in your chest)
• Chest pain

How Is Sick Sinus Syndrome Diagnosed?

The turning point for Julie came thanks to her sister, Annie Luetkemeyer, who had just graduated from medical school. During a family vacation, her sister, still in the habit of carrying a stethoscope, insisted on listening to Bowen's heart. "That is not what they've been telling you, and it's not runner's heart or whatever. That means you need to go to a cardiologist," her sister declared, refusing to let the issue drop

Your healthcare provider might suspect SSS based on your symptoms, but these symptoms can be common to many other conditions. To confirm a diagnosis, your provider will likely perform an electrocardiogram (ECG), which records your heart's electrical activity, rate, and rhythm. If you're not experiencing symptoms during the ECG, the results may appear normal. Other diagnostic tests that may be used include:

Stress test: An ECG performed while you exercise on a treadmill.

Holter monitor: A portable device you wear for over 24 hours to continuously record your heart's electrical activity.

Event recorder: A device worn for several days that records your heart rate only when symptoms occur.

Electrophysiologic testing: A hospital procedure where catheters are threaded into your heart through a vein in your thigh to study its electrical system.

Echocardiogram: An ultrasound of your heart to check for structural problems.

Treatment Options For SSS

About a month after her sister's crucial warning, Bowen was filming the pilot for "Ed" when she was faced with the reality of needing a pacemaker. Initially, the news was daunting. "I was like, 'Oh my God. My life is over. This is so weird. I'm gonna die,'" she recalled. However, doctors explained that while the condition wasn't immediately fatal, it would lead to her frequently passing out.

Bowen described a sensation of lightheadedness, particularly when she was relaxed, feeling "like I'd been holding my breath for a while." The critical warning that solidified her decision was the risk of passing out while driving and potentially harming someone. "Oh, well, then give me the Goddamn pacemaker," she decided.

Her pacemaker is now set to ensure her heart rate doesn't drop below 45 beats per minute. She shared that the surgical insertion was done discreetly through her armpit, leaving no visible scar. While she's had to have the batteries replaced three times, she largely forgets about it now, a testament to how seamlessly it has integrated into her life.

While this is one way to treat her condition, here are some other ways your doctor may choose to go about your treatment,

Medication adjustment

If certain medications are contributing to your SSS, your healthcare provider may change your prescription.

Blood thinners

Because SSS can increase the risk of blood clots forming in the heart and leading to a stroke, you may be prescribed blood thinners as a preventive measure.