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Ozempic works by mimicking the hormone GLP-1, which suppresses hunger and regulates blood sugar levels. All semaglutide medications work like that. These drugs are great for those trying to shed extra pounds in their body, however, there's a catch. All of these blockbuster weight loss drugs are synthetic and not sustainable in the long run. But wait, what if I told you that researchers have found a component in your everyday breakfast that can do just the same?
Researchers also tested several types of dietary fibre, including dextrin, pectin, resistant starch, and cellulose. However, none of these fibres showed the same impact on weight reduction or fat loss as beta-glucan, despite significantly altering the gut microbiome. "We know that fibre is important and beneficial; the problem is that there are so many different types of fibre," explained Frank Duca, a biomedical scientist from the University of Arizona. The study aimed to determine which type of fibre is most effective for weight loss and glucose regulation, providing valuable insights for consumers and the agricultural industry.
Dietary fibre is a plant-based nutrient found in whole grains, fruits, and vegetables. It serves as the primary energy source for beneficial gut bacteria, playing a vital role in digestive health. Despite its importance, less than 5 per cent of people in the US consume the recommended 25–30 grams of fibre per day. A high-fiber diet is known to be protective against weight gain. Foods rich in fibre tend to have lower energy density, meaning they provide fewer calories per gram of food. This allows individuals to consume the same volume of food while reducing their caloric intake. Additionally, fibre-rich foods are often bulky and filling, promoting satiety.
Soluble fibre, such as beta-glucan, forms a gel-like substance in the digestive tract, slowing stomach emptying and extending the feeling of fullness. This delayed digestion also results in a slower absorption of sugars, helping to maintain stable blood sugar levels and prevent insulin spikes, which have been linked to obesity and an increased risk of diabetes.
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Tramadol, part of the opioid class, is commonly prescribed for moderate to severe pain, such as after an injury or surgery. Because of its potency and ability to manage pain effectively, doctors may turn to tramadol when other pain relievers fail. It is usually available as a tablet or capsule, but can also be given as a liquid or injection, the latter often used in hospital settings.
In certain cases, ongoing tramadol use may be necessary, especially for those living with chronic pain conditions. While it can be essential for daily pain management, it is important to be aware that prolonged use may increase the risk of unwanted side effects.
Tramadol is a dual-action opioid that affects serotonin and norepinephrine pathways, often described as a middle-ground painkiller, stronger than non-opioid medications but thought to be less addictive than morphine. It is prescribed for moderate-to-severe pain, including both post-surgical discomfort and long-term chronic conditions.
Globally, prescriptions have surged, partly because of the perception that tramadol is safer and carries a lower risk of dependence compared with stronger opioids.
The NHS has warned about the risks of long-term tramadol use, including hyperalgesia. This condition can make you more sensitive to pain, so that ordinary aches feel much stronger or more intense than usual. If this occurs, your doctor may recommend gradually reducing the tramadol dose to help ease these heightened sensations.
Over time, the body can develop a tolerance to tramadol. This means you may need higher doses to achieve the same level of pain relief that you once got from a smaller amount.
Being an opioid, tramadol carries a risk of addiction, particularly when used for a long stretch. Signs that dependency is developing could include difficulty stopping the medication or taking it more often than prescribed.
Stopping tramadol suddenly can also lead to withdrawal symptoms, such as feelings of anxiety or restlessness. If this happens, your GP may reassess your treatment plan to ensure you are on the safest dose necessary to manage your pain effectively.
Recent research, including a systematic review and meta-analysis by Medscape, suggests that tramadol’s effectiveness for chronic pain may be limited. The studies found only minimal pain relief while noting that serious side effects were twice as likely among tramadol users, particularly cardiac complications.
“Considering the modest pain relief and heightened risk of harm, tramadol should be reconsidered for chronic pain management,” said Dr. Jehad Ahmad Barakji of the Centre for Clinical Intervention Research at Rigshospitalet in Copenhagen, speaking to Medscape Medical News.
Researchers did note that the quality of evidence varied, with certainty ranging from low to moderate. Common serious issues involved the heart, such as chest pain, coronary artery disease, and heart failure. Non-serious but bothersome side effects — including nausea, dizziness, constipation, and drowsiness, were frequent and often led patients to stop taking the drug.
This article is for informational purposes only and is not a substitute for professional medical advice. Always consult your doctor or a qualified healthcare professional regarding any questions about medications or health conditions.
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If you often find yourself tossing in bed or staring at the ceiling at 3 a.m., you might be wondering whether magnesium, the mineral known for promoting calm and relaxation, could be the key to better sleep. It may be worth exploring, especially if your body lacks enough of it, says Denise M. Millstine, M.D., assistant professor of medicine and director of integrative medicine and health at Mayo Clinic in Arizona.
Those most at risk of magnesium deficiency include women, older adults, people who drink alcohol regularly, and anyone whose diet relies heavily on processed or convenience foods.
So, does magnesium truly live up to the hype? It’s certainly trending. According to Growth Market Reports, sales of topical magnesium products reached $421.6 million in 2023, while Grand View Research valued the magnesium supplement market at $29.3 million in 2024.
Magnesium supports over 300 essential body functions and plays a major role in healthy aging. Still, the belief that it can be a hidden cure-all deserves a closer look. To separate science from speculation, let’s examine two widely circulated claims on social media: that magnesium guarantees better sleep, and that it can ease anxiety or depression.
Magnesium helps regulate several processes in the body, including the balance of neurotransmitters, the chemicals that allow nerve cells to communicate, Dr Millstine explains. These messengers influence mood, sleep, memory, and muscle control.
“Some neurotransmitters stimulate, while others calm,” she says. “Magnesium helps maintain balance between the two.” If you struggle with anxiety or racing thoughts at bedtime, magnesium might help tilt the scale toward the calming side, making it easier to drift off.
Dr Millstine adds that people with “busy minds” may notice the most improvement. “Some individuals can suppress their anxious thoughts during the day, but when night falls, their minds grow louder and harder to quiet,” she explains.
Experts do not advise magnesium supplements for people who aren’t deficient in the mineral.
While generally safe, it’s best to consult a doctor before adding magnesium to your routine, especially if you have existing health issues. The supplement may not be suitable for those taking certain diuretics, antibiotics, or heart medications.
Most users experience no side effects, though high doses can lead to digestive problems. Possible reactions include:
People with kidney problems are more vulnerable to magnesium toxicity, as their bodies may struggle to clear excess amounts.
The ideal magnesium dosage ranges between 200 and 400 mg daily, depending on the product. This typically provides the full recommended daily intake.
According to Healthline, the safe upper limit for magnesium supplements is 350 mg per day. Staying within this range helps reduce the risk of digestive discomfort and other side effects.
This article is intended for general informational purposes only and should not be taken as medical advice. Always consult your doctor or a qualified healthcare professional before starting any supplement or treatment.
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In a recent post, Dr Sudhir Kumar busted 10 common misconceptions people have about health. Health misconceptions occur very often, while you may not realize it; we also perpetuate these myths very often.
To help people avoid these, Dr Sudhir Kumar, a Hyderabad-based Neurologist, listed misconceptions about common diseases. The reason why it is important to know what to believe and what not to, is because these myths can lead people to ignore obvious health signs, like signs of heart attacks, because they believe they are unlikely to get one themselves.
Here are 10 common health misconceptions you should know about, according to Dr Sudhir Kumar.
Fact: Stroke Can Happen at Any Age. Many people think strokes are just an old-age problem, but this is false. Strokes can strike young adults, even in their 30s or 40s. Having high blood pressure, diabetes, or smoking greatly increases the risk, regardless of your age. Staying healthy is crucial for everyone.
Fact: Heart Attacks Can Be Silent or Mild. It’s a common belief that a heart attack is always a sudden, crushing pain. However, many heart attacks are mild or "silent," causing only slight discomfort or unusual fatigue. This is especially common in women and people with diabetes, making it easy to overlook.
Fact: Fever is Your Body's Natural Defense. Fever is how your immune system fights off infections. You only need to treat it if the temperature is dangerously high or if you feel very uncomfortable. For mild fevers, let your body do its job; focus on rest and hydration instead.
Fact: Antibiotics Only Fight Bacteria, Not Viruses. Colds and the flu are caused by viruses, and antibiotics are useless against them. Taking antibiotics unnecessarily will not help and actually makes them less effective against real bacterial infections later on. Only use them when prescribed for bacteria.
Fact: Hypertension is Usually a Silent Condition. High blood pressure (hypertension) is often called the "silent killer" because it rarely causes noticeable symptoms until it's very severe. This is why getting your blood pressure checked regularly is essential. You need routine checks to catch it early before it causes damage.
Fact: Diabetes is Complex, Not Just Caused by Sugar. While eating too much sugar makes Type 2 diabetes worse, the disease is primarily caused by a mix of genetics, not exercising enough, and the body's inability to properly use insulin (insulin resistance). It is a lifestyle disorder, not just a sugar problem.
Fact: Harmful UV Rays Get Through Clouds Daily. Many people skip sunscreen on cloudy or overcast days, but this is a mistake. Ultraviolet (UV) rays from the sun, which damage your skin, can easily penetrate clouds. You need to apply sunscreen every single day for proper protection against skin aging and cancer.
Fact: Lifestyle and Environment Cause Most Cancers. While certain rare cancers are linked to inherited genes, the majority of cancer cases are actually caused by daily habits and environmental factors. Things like smoking, diet, lack of exercise, and sun exposure play a much bigger role in cancer risk for most people.
Fact: Stopping Treatment Early Can Cause Relapse. You must always finish the full course of medicine as directed by your doctor. Stopping treatment too soon—especially antibiotics or blood pressure medication—allows the illness to come back or get worse. Follow the prescription to fully clear the infection or manage the condition.
Fact: Mental Health Issues Are Real Medical Conditions. Conditions like depression or anxiety are genuine medical illnesses, just like diabetes or heart disease. They are not a sign that a person is weak or failing. Seeking help from a professional shows courage and strength, taking an active step toward recovery and well-being.
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