GLP-1 agonists, such as Ozempic, have gained widespread attention for their weight-loss effects. As it was originally designed as medication to treat Type-2 Diabetes, there have been many who are also experiencing its negative effects. Their growing popularity, paired with negative effects, has prompted people to explore ways to tailor these drugs to individual needs. This has given rise to the practice of microdosing.What Is Microdosing?Microdosing implies that a person is consuming smaller or lesser amounts of the drug (Ozempic or any other weight loss medication) as is normally consumed. Typically, it is done via drugs from compounding pharmacies because of the way that name-brand medications are made and delivered. US Food and Drug Administration (FDA) describes compounding as a "process of combining, mixing, or altering ingredients to create a medication tailored to the needs of a patient." Notably, the agency on its website clearly states that they don't approve compounded drugs like it does traditional drugs.Ozempic Can Easily Be MicrodoseOzempic is one of the only GLP-1 agonists that could potentially be micro-dosed because of the way it's packaged, that is, in a Pen. Others like Wegovy and Zepbound come in autoinjectors, therefore, they cannot be hacked for a smaller dose. Now, there are a lot of reasons, people can microdose Ozempic, like trying to save money and minimize its negative side effects. However, most of the experts do not really recommend microdosing as they worry about the risk of procuring its from a compounded pharmacy. Moreover, taking a very less dose does not work. As mentioned earlier, government health agencies also do not recognise these compounded medicines due to safety concerns.How Does Ozempic Function?The first thing to remember here is that Ozempic is a brand-name medicine that contains semaglutide as its active ingredient. Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed.GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outburst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.However, it is important to note that losing weight includes not just fat but muscle as well. Losing too much muscle can lead to reduced strength and a shorter life span. Notably, records show that most people who start taking them stop at 12 weeks; therefore, it is important for some but not for others. The drug also has many side effects, like nausea, vomiting, diarrhoea, and abnormal discomfort.