A new study from the University of Edinburgh found that the brains of cats with dementia show changes very similar to those seen in humans with Alzheimer's disease. These findings are a big step forward and could lead to new treatments for both people and pets. For the first time, researchers can see how the brains of cats naturally change as they get older and develop dementia, which provides a much more realistic picture of the disease than previous research has been able to. This discovery is a huge breakthrough because it offers a new way to study the disease and find better treatments. How Can Cats Help Us Treat Dementia? In the past, scientists have relied on genetically modified rodents to study Alzheimer's. However, rodents do not naturally get dementia. Cats, on the other hand, do. They also show similar symptoms to humans, such as confusion and changes in sleep patterns. Because of these similarities, cats provide a more accurate and natural model for studying the disease. Dr. Robert McGeachan, the study's lead researcher, said that because cats naturally develop these brain changes, they may help scientists explore whether promising new treatments for human Alzheimer’s could also help our aging pets. This research benefits both species and their caregivers. What Does Cat Dementia Reveal About Humans? Scientists at the University of Edinburgh examined the brains of 25 cats after they passed away. They found that older cats and those with dementia had a build-up of a toxic protein called amyloid-beta. This protein is a key sign of Alzheimer’s disease. The research showed that this protein was found in the synapses—the connections between brain cells. These connections are essential for healthy brain function. When they are lost, a person's memory and thinking skills decline. The research also discovered that some support cells in the cats' brains were "eating" these damaged synapses. This process, known as synaptic pruning, is a normal part of brain development but can contribute to the loss of synapses in dementia. Also Read: Meet 'Doctor Peyo' - The Therapy Horse Who Is Changing End-of-Life CareWhy Is Dementia On The Rise? Dementia is a very common disease among older people, and since the elderly population is growing quickly worldwide, the number of people living with dementia is expected to increase. A study published in the Journal of the Neurological Sciences journal, based in Wales, UK, looked at medical records from 1999 to 2018 to understand this trend. The study included over 161,000 dementia diagnoses from nearly 117,000 people. The study found a few important things: Older Age at Diagnosis The average age for a dementia diagnosis has been going up. This means fewer younger people are being diagnosed with the disease. More Cases and Longer Lives The number of new dementia cases has risen and so has the total number of people living with the disease. The study also found that people with dementia are living longer than they used to, even with their diagnosis. This is not just limited to the UK, dementia cases in the US are also estimated to double by 2060. Published in the journal Nature Medicine, followed nearly 16,000 Americans since 1987, found that the overall lifetime risk for developing dementia for a middle-aged American is 42 percent. This risk is higher for women (48 percent) than for men (35 percent), mainly because women tend to live longer. The risk also increases with age, rising to over 50 percent for people who live to be 75. The study's authors believe that previous estimates were too low because of poor record-keeping and a lack of data on early-stage cases and racial minorities. According to the study, preventing heart diseases like high blood pressure and diabetes can also help slow cognitive decline and prevent dementia. Other factors linked to a higher risk include obesity, unhealthy diets, lack of exercise, and poor mental health.