Ovarian cancer is still one of the most challenging gynecological cancers, often diagnosed at an advanced stage because of the elusive nature of its symptoms. Even with the progress of medical research, the mortality rate of late-stage ovarian cancer continues to be appallingly low, thus necessitating prevention and early detection of the disease. The health of women, especially reproductive health, largely determines the risk factors of ovarian cancer. From genetic susceptibility to lifestyle habits, a variety of factors affect vulnerability to the disease.Amidst continuing research into preventive measures, an interesting discovery has been made—birth control pills, which have been used for decades for birth control and hormone regulation, may provide a remarkable protective benefit against ovarian cancer. A pioneering study indicates that women who use oral contraceptives over the age of 45 may lower their risk for developing ovarian cancer by a staggering 43%. This finding not only redefines the debate surrounding reproductive health but also highlights the larger significance of hormonal control in the prevention of disease. But how does birth control impact cancer risk, and what does this portend for women around the world? Here's what the new research shows.Australian research published in the International Journal of Gynaecological Cancer indicates that these contraceptives could provide a further, life-saving advantage: a major decrease in the risk of ovarian cancer. The research examined data from 221,732 women between the ages of 37 and 73, looking at almost 3,000 varied characteristics concerning health, use of medication, diet, lifestyle, metabolic and hormonal conditions. During a follow-up duration of almost 13 years, 1,441 of the women were found to have ovarian cancer. The results indicated that women who ever used birth control pills had 26% decreased risk of having ovarian cancer. Even more surprisingly, those taking oral contraceptives after age 45 had a 43% decrease in risk.Why Ovarian Cancer Remains a Major Concern?Ovarian cancer is among the most lethal types of gynecologic cancer and is usually diagnosed at a late stage. About 70% of ovarian cancer is diagnosed only after the disease has advanced considerably. If diagnosed at a late stage, the five-year survival rate is less than 30%. Early detection raises the survival rate to more than 90%.Given that ovarian cancer produces no overt signs, prevention and risk-reduction are the way to go. The results from the study propose that birth control pills could represent a valuable safety measure that changes the course for preventing ovarian cancer in the years to come. How Do Birth Control Pills Reduce Ovarian Cancer Risk?Oral contraceptives include artificial forms of estrogen and progesterone, two hormones that control ovulation. Studies indicate that decreasing the frequency of ovulation is a major factor in decreasing the risk of ovarian cancer. Women who ovulate fewer times over the course of their lives are exposed to lower doses of hormones that can lead to cancerous cell development.Research shows that the use of birth control pills for five or more years could reduce ovarian cancer risk by as much as 50%. Amazingly, the protective effects can continue for as long as 25 years after the pill has been discontinued. In fact, some research suggests that oral contraceptives might also offer protection for women who carry BRCA genetic mutations, which already place them at high risk for ovarian cancer.Other Cancer-Related Effects of Birth Control PillsAlthough the study points to oral contraceptives' advantages of lowering the risk of ovarian cancer, scientists have also investigated how they affect other cancers.Lower Risk of Endometrial CancerWomen who use oral contraceptives can also lower their risk of uterine cancer. The research mentioned that at least four years of birth control pills can cut the risk of uterine cancer in half, and this benefit can extend up to 10 years after stopping.Slightly Elevated Risk of Breast and Cervical CancerOn the other hand, some studies have indicated that long-term use of oral contraceptives increases the risk of breast and cervical cancer slightly. Again, this risk is minimal and loses its elevation after five years of discontinuing the pill. Moreover, since the majority of women use birth control pills during their 20s, 30s, and early 40s—years when they have a low baseline risk for cancer—the overall effect is tiny.Other Important Factors Determining Cancer RiskOral contraceptives can be involved in lowering ovarian and endometrial cancer risk, but they are not the sole determining factors. A number of lifestyle and genetic factors also determine cancer risk.HPV and Cervical CancerCervical cancer is more associated with human papillomavirus (HPV) infections than with birth control pills. Thus, being vaccinated against HPV and receiving regular screenings continue to be important in reducing cervical cancer risk.Lifestyle and GeneticOther cancer risk factors are obesity, reproductive history, and family genetics. Keeping fit, being aware of hormonal fluctuations, and frequently visiting healthcare providers for individualized risk evaluations can have a considerable influence on cancer prevention.For women who wish to make responsible choices regarding their reproductive lives, it is important to discuss with their healthcare providers the advantages and disadvantages of oral contraceptives. As scientific knowledge continues to improve, birth control pills can not only be a contraceptive but a potent cancer prevention tool.