The debate about how weed or cannabis supplements are health friendly are not has been going on for a while. While there are certain benefits of it for psychological health, it still has physical consequences. When it comes to surgeries and healing, there are many things that need to be considered. Doctors know that many cancer patients use cannabis to help with symptoms like nausea, pain, and anxiety. In fact, some studies show that more than half of cancer patients, and up to 80% of those who also smoke tobacco, use it. But there's a big missing piece of information: How does cannabis use affect the body’s ability to heal from surgery? As we know, smoking negatively affects how well your wounds heal, however, when we swap the components to cannabis, how different is the effect? How Does Cannabis Affect Recovery From Cancer Surgery?To answer this, Dr. Lurdes Queimado at the University of Oklahoma is leading a first-of-its-kind study focused on patients with head and neck cancers. These cancers are becoming more common, fueled by smoking, heavy drinking, and HPV infections. The primary treatment for them is often surgery, which can be life-changing, as it often alters a person's appearance and affects their ability to breathe and swallow. Because of these intense surgeries, patients often need reconstructive surgery afterward. The goal of this research is to give doctors clear, reliable information so they can properly advise their patients on how cannabis might affect their recovery. How the Study Works This study will follow 220 adult patients over a six-month recovery period after their surgery. It's unique because it's a "prospective" study, meaning the researchers are tracking patients as they heal, rather than just looking at old records. To make sure the data is accurate, they’ll also use blood tests to confirm if patients are using cannabis. Cannabis usersTobacco usersBoth cannabis and tobacco usersThose who use neitherOver the six months, the research team will closely watch each patient for infections, bleeding, and other medical complications. They’ll also carefully assess how well their scars are healing. The study will also explore if the way someone uses cannabis—whether by smoking, vaping, or using edibles—makes a difference in their recovery. What Doctors Expect to Find Based on some early research, Dr. Queimado and her team have a hypothesis: smoking cannabis could have a negative impact on wound healing. Their initial findings suggest that even in healthy people, cannabis can increase inflammation and weaken the immune system. Both of these effects could potentially slow down healing and lead to more problems after surgery. This research could have a huge impact. Not only could it help patients with head and neck cancer, but it could also provide valuable information about how cannabis affects other chronic diseases where inflammation and a strong immune system are important. Ultimately, the findings could shed light on how cannabis interacts with other cancer treatments like chemotherapy and radiation, giving doctors a much clearer picture of its overall effects on a patient's health.