Ishita Roy

Colon Cancer Is The Third Most Common Cancer In Men: Symptoms, Treatment And Prevention

Colon Cancer

<span>Colon <a href="https://www.healthandme.com/health/cancer">Cancer</a></span> or Colorectal <span>Cancer</span> (CRC) contributed to 9.2% of all major cancer worldwide, as per the Globocan Report 2018. The report mentions that over 1.8 million new cases were reported, with it being the third most common cancer in males. This impacts up to 7,46,000 new cases in males and 6,14,000 in females. 

It is a disease of large bowel and a type of cancer that originates from the rectum or colon. A person's colon, cecum, rectum and anus make up the large intestine. 

The ileocecal valve that is located at the opening between the ileum and the large intestine controls the flow of chyme from the small intestine to the large intestine. 

It happens when abnormal cells invade the wall of the rectum and neighbouring tissue. These are called polyps or growths in the inner lining of the colon. 

This starts in the innermost lining of the colon in the mucosa, which contains cells that release mucus and other fluids. When the cells mutate, it creates a colon polyp. Over time, colon polyps become cancerous. If it is left untreated, it could work its way through a layer of tissue, and muscle and then to the outer layer of your colon. 

It can also spread to other parts of your body via lymph nodes or your blood vessels. 

If you notice blood in your stool or notice that your stool looks bright red, you must go see a doctor. It may also be haemorrhoids or anal tears. 

If you have persistent constipation or diarrhoea. Or if you feel like you need to poop every time you go to the bathroom, it is advisable to go see a doctor. 

<strong>Belly Pain or Bloated Stomach</strong>

Speak to your healthcare provider if you feel sudden abdominal pain or feel bloated, which lasts more than a week, or if you feel nauseated, go see a doctor. 

Other symptoms include unexplained weight loss, vomiting, fatigue and shortness of breath. 

Certain lifestyle choices can increase the risk of colon cancer. 

Smoking: using tobacco products whether it is chewing or smoking can cause colon cancer

Alcohol use, eating high-fat and high-calorie foods and consuming processed meat can also lead to colon cancer. Furthermore, a sedentary lifestyle without any physical activities. 

Certain medical conditions can increase the risks of colon cancer, including inflammatory bowel disease, lynch syndrome and familial adenomatous polyposis. If you have a family history of colon cancer, it may increase your risk of getting colon cancer. 

There are certain tests that can help you with its diagnosis:

Complete Blood Count (CBC), comprehensive metabolic panel (CMP), and carcinoembryonic antigen assay (CEA) which detects the cancer cells and normal cell release in your bloodstream. A high CEA level may be a sign of colon cancer. 

Other tests include X-rays, CT scan, <span>MRI scan</span> PET scan, ultrasound, biopsy. 

<h5><span rel="noindex">Treatment</span> Of Colon Cancer</h5>

<strong>Polypectomy</strong>: This procedure removes cancerous polyps from the colon.

<strong>Partial Colectomy (Colon Resection)</strong>: Surgeons remove the portion of the colon containing the tumor, along with some surrounding healthy tissue, and reconnect the healthy sections of the colon in a process called anastomosis.

<strong>Surgical Resection with Colostomy</strong>: Similar to a colectomy, but if reconnection isn’t possible, the bowel is moved to an opening in the abdominal wall, where waste is collected in a bag (colostomy).

<strong>Radiofrequency Ablation</strong>: This procedure uses heat to destroy cancer cells.

Surgery may be combined with adjuvant therapy, which is treatment before or after surgery. Additional treatments, especially for cancer that has spread or returned, may include:

<strong>Chemotherapy</strong>: Drugs are used to shrink tumours and alleviate symptoms.

<strong>Targeted Therapy</strong>: This treatment focuses on specific genes, proteins, and tissues that contribute to cancer growth. A common method is monoclonal antibody therapy, where lab-made antibodies attach to and destroy cancer cells.

<strong>Avoid Tobacco</strong>: If you smoke, ask your healthcare provider for help quitting through smoking cessation programs.

<strong>Limit Alcohol</strong>: Consume alcoholic beverages in moderation.

<strong>Maintain a Healthy Weight</strong>: Keep your weight in a healthy range to lower your risk.

<strong>Eat a Balanced Diet</strong>: Include plenty of fruits and vegetables in your meals, while reducing red meat, processed foods, and high-fat options. Drinking coffee may also reduce the risk of colon cancer.

<strong>Monitor Family Medical History</strong>: If colon cancer or advanced polyps run in your family, or if a relative had cancer before age 45, share this information with your healthcare provider.

<strong>Follow Screening Guidelines</strong>: Regular screenings are key to early detection. If you have chronic irritable bowel disease or a family history of colon cancer, your provider may recommend starting screenings earlier than age 45.

Health Conditions A-Z

health

cancer cases

mri scan

cancer

cancer prevention

colon cancer

treatment

Amid Rising Indo-Pak Tensions, Here's How You Can Manage Your Anxiety

Couscous Is More Processed Than You Think—But It's Still Healthy. Here's Why

New Game-Changing Drug Could Bring Your 'Bad' Cholesterol Under Control; 10 Natural Hacks To Follow

Health & Wellness

​Ghee For Ayurveda: Why It Should Be A Part Of Your Diet​

Symptoms Of Ovarian Cancer You Should Know

Yoga Poses That Can Build Core Strength

Biotin-Rich Foods You Should Add To Your Diet

Unexpected Physical Signs Of Stress

Simple And Affective Guide To Stop A Panic Attack

Signs Of Heat Exhaustion In Children

10 Heart Symptoms You Shouldn't Ignore

Lower Your Cholesterol With These Foods

Food Myths You Should Stop Believing

Work Stressing You Out? Tips To Handle Toxic Workspaces

Looking To Gain Weight? High-Calorie Healthy Foods To Try

​Pomegranates Are A Must For Summer, Here’s Why​

​How Does Being A Night Owl Change Your Brain​

​Can Nightlights Affect Your Child’s Sleep​

How To Decide Whether You Should Do Cardio Or Strength Training?

Enjoying Hobbies As An Adult Is More Important Than You Realize

Screentime Matters For Parents Too, Here's How It Causes Issues

Why Should We Discard Expired Prescription Drugs?

Perks Of Having Home Plants For Your Health

Signs You Are Dealing With Depleted Mother Syndrome

Protein-Rich Fruit Smoothies You Must Try

Ways You Can Reach Out To Someone In A Mental Health Crisis

These Things Are Causing You To Lose Sleep

10 Healthy Soups That Support Weight Loss

Easy Lunch Ideas For People With Type 2 Diabetes

9 Bodyweight Exercises To Boost Strength Anytime, Anywhere

Iron-Rich Foods Every Woman Should Include in Her Diet

Ayurvedic Foods To Cool Your Body Naturally

10 Ways Fluctuating Cortisol Levels Can Affect You Physically

Unexpected Factors That Affect Your Blood Sugar

Foods People With PCOS Should Avoid

Do Sleep Trackers Actually Work? Things You Should Know About

Avoiding These Proteins Is Causing Your Health To Deteriorate

Not Sure Whether It Is Fatigue Or Burnout? Answer These 10 Questions

Experiencing Drained Energy Mid-Day? 10 Ways To Fix It

Common Hair Care Habits That Are Causing You Hair Damage

Signs You May Have Avoidant Personality Disorder

These Foods Seem Healthy But Add Unexpected Calories To Your Diet

Is It Safe To Exercise In This Heat? Risks And Precautions To Remember

Colon Cancer or Colorectal Cancer (CRC) contributed to 9.2% of all major cancer worldwide, as per the Globocan Report 2018. The report mentions that over 1.8 million new cases were reported, with it being the third most common cancer in males. This impacts up to 7,46,000 new cases in males and 6,14,000 in females. What Is Colon Cancer?It is a disease of large bowel and a type of cancer that originates from the rectum or colon. A person's colon, cecum, rectum and anus make up the large intestine. The ileocecal valve that is located at the opening between the ileum and the large intestine controls the flow of chyme from the small intestine to the large intestine. It happens when abnormal cells invade the wall of the rectum and neighbouring tissue. These are called polyps or growths in the inner lining of the colon. This starts in the innermost lining of the colon in the mucosa, which contains cells that release mucus and other fluids. When the cells mutate, it creates a colon polyp. Over time, colon polyps become cancerous. If it is left untreated, it could work its way through a layer of tissue, and muscle and then to the outer layer of your colon. It can also spread to other parts of your body via lymph nodes or your blood vessels. What Are The Symptoms?Blood In Your StoolIf you notice blood in your stool or notice that your stool looks bright red, you must go see a doctor. It may also be haemorrhoids or anal tears. Change In Bowel HabitsIf you have persistent constipation or diarrhoea. Or if you feel like you need to poop every time you go to the bathroom, it is advisable to go see a doctor. Belly Pain or Bloated StomachSpeak to your healthcare provider if you feel sudden abdominal pain or feel bloated, which lasts more than a week, or if you feel nauseated, go see a doctor. Other symptoms include unexplained weight loss, vomiting, fatigue and shortness of breath. What Causes It?Certain lifestyle choices can increase the risk of colon cancer. Smoking: using tobacco products whether it is chewing or smoking can cause colon cancerAlcohol use, eating high-fat and high-calorie foods and consuming processed meat can also lead to colon cancer. Furthermore, a sedentary lifestyle without any physical activities. Certain medical conditions can increase the risks of colon cancer, including inflammatory bowel disease, lynch syndrome and familial adenomatous polyposis. If you have a family history of colon cancer, it may increase your risk of getting colon cancer. How To Get Diagnosed?There are certain tests that can help you with its diagnosis:Complete Blood Count (CBC), comprehensive metabolic panel (CMP), and carcinoembryonic antigen assay (CEA) which detects the cancer cells and normal cell release in your bloodstream. A high CEA level may be a sign of colon cancer. Other tests include X-rays, CT scan, MRI scan PET scan, ultrasound, biopsy. Treatment Of Colon CancerPolypectomy: This procedure removes cancerous polyps from the colon.Partial Colectomy (Colon Resection): Surgeons remove the portion of the colon containing the tumor, along with some surrounding healthy tissue, and reconnect the healthy sections of the colon in a process called anastomosis.Surgical Resection with Colostomy: Similar to a colectomy, but if reconnection isn’t possible, the bowel is moved to an opening in the abdominal wall, where waste is collected in a bag (colostomy).Radiofrequency Ablation: This procedure uses heat to destroy cancer cells.Surgery may be combined with adjuvant therapy, which is treatment before or after surgery. Additional treatments, especially for cancer that has spread or returned, may include:Chemotherapy: Drugs are used to shrink tumours and alleviate symptoms.Targeted Therapy: This treatment focuses on specific genes, proteins, and tissues that contribute to cancer growth. A common method is monoclonal antibody therapy, where lab-made antibodies attach to and destroy cancer cells.PreventionAvoid Tobacco: If you smoke, ask your healthcare provider for help quitting through smoking cessation programs.Limit Alcohol: Consume alcoholic beverages in moderation.Maintain a Healthy Weight: Keep your weight in a healthy range to lower your risk.Eat a Balanced Diet: Include plenty of fruits and vegetables in your meals, while reducing red meat, processed foods, and high-fat options. Drinking coffee may also reduce the risk of colon cancer.Monitor Family Medical History: If colon cancer or advanced polyps run in your family, or if a relative had cancer before age 45, share this information with your healthcare provider.Follow Screening Guidelines: Regular screenings are key to early detection. If you have chronic irritable bowel disease or a family history of colon cancer, your provider may recommend starting screenings earlier than age 45.

colon cancer is the third most common cancer in men: symptoms, treatment and prevention

Health and Me

Riya Baibhawi

Becoming Forgetful With Age? Signs That Tell It's 'More Serious' Than Just Aging

becoming forgetful with age? signs that tell it's 'more serious' than just aging

Teen Dies After Months On Extreme Water-Only Diet; Symptoms And Risks Of Anorexia

teen dies after months on extreme water-only diet following youtube video; symptoms and risks of anorexia

What Is Altruism? Cancer Patient Shares How Emotional Response Is Directly Linked To Longevity

world ovarian cancer day: what is altruism? how your emotional response is directly linked to longevity

Number Of Depressed Adults Increased In US During Pandemic

number of depressed adults increased in us during pandemic

<span>India</span> launched massive strikes on terror camps in Pakistan and PoK late night yesterday. The aerial operation came in response to the Pahalgam terror attacks that resulted in 26 people getting killed and several others getting injured last month. As tensions continue to rise in both countries, people in India have been asked to participate in mock drills to prepare for possible emergencies. 

While people on both sides of the border prepare for a possible war, <span>mental health</span> experts have raised concerns about the psychological cost of such a situation. They opined that it could result in escalated stress, anxiety and fear. A recent study published in the International Journal of Mental Health Systems earlier this year aunderscored the escalating mental health crisis in Ukraine, exacerbated by the ongoing conflict. The study reveals that prior to the full-scale invasion, approximately 30% of Ukrainians had experienced mental health disorders, with depressive disorders surpassing the EU average. The conflict has severely strained the nation’s mental health infrastructure, underscoring the urgent need for comprehensive reforms and targeted interventions to address the rising rates of anxiety, <span>PTSD</span>, and depression among civilians and displaced populations.

<h2>How To Manage Anxiety In Such a Situation, As Per Expert</h2>

Dr Shilpi Saraswat, Clinical Psychologist at Sakra World Hospital, Bengaluru, recommends avoiding unnecessary exposure to news and staying in a supportive social circle when stuck in such situations. Here are a few steps you should follow: 

1. Limit news exposure: Set boundaries on news consumption to avoid excessive exposure.

2. Stay informed, not overwhelmed: Focus on credible sources and updates rather than constant coverage.

3. Practice self-care: Engage in activities that promote relaxation and stress reduction, such as exercise, meditation, or hobbies.

4. Social support: Connect with loved ones, friends, or support groups to share feelings and concerns.

5. Grounding techniques: Use mindfulness exercises, deep breathing, or physical activity to stay present and focused.

<h2>Coping Strategies For Families And Children</h2>

If you are someone who resides with the elderly and children, Dr Saraswat recommends having an open discussion with them on the current situation. "Encourage honest discussions about feelings and concerns," he said. Moreover, you must provide reassurance and comfort to them. To avoid anxieties, it is also advised to maintain regular routines and activities to provide a sense of stability. You should also acknowledge and validate children's feelings, helping them process emotions. Moreover, monitor and limit children's exposure to news and media coverage.

<h2>Differentiating Normal Stress Responses from Serious Mental Health Concerns</h2>

1. Normal stress responses: Anxiety, worry, and fear are common reactions to stressful situations.

2. Signs of more serious concerns: Persistent symptoms, such as intrusive thoughts, nightmares, or avoidance behaviours, may indicate PTSD or other mental health concerns.

3. Panic disorders: Recurring panic attacks, persistent fear of having attacks, or avoidance behaviours may indicate a panic disorder.

4. Seek professional help: If symptoms persist or interfere with daily life, consult a mental health professional for guidance and support.

Mental Health

India-Pakistan War

India

war anxiety

Ptsd

India launched massive strikes on terror camps in Pakistan and PoK late night yesterday. The aerial operation came in response to the Pahalgam terror attacks that resulted in 26 people getting killed and several others getting injured last month. As tensions continue to rise in both countries, people in India have been asked to participate in mock drills to prepare for possible emergencies. While people on both sides of the border prepare for a possible war, mental health experts have raised concerns about the psychological cost of such a situation. They opined that it could result in escalated stress, anxiety and fear. A recent study published in the International Journal of Mental Health Systems earlier this year aunderscored the escalating mental health crisis in Ukraine, exacerbated by the ongoing conflict. The study reveals that prior to the full-scale invasion, approximately 30% of Ukrainians had experienced mental health disorders, with depressive disorders surpassing the EU average. The conflict has severely strained the nation’s mental health infrastructure, underscoring the urgent need for comprehensive reforms and targeted interventions to address the rising rates of anxiety, PTSD, and depression among civilians and displaced populations.How To Manage Anxiety In Such a Situation, As Per ExpertDr Shilpi Saraswat, Clinical Psychologist at Sakra World Hospital, Bengaluru, recommends avoiding unnecessary exposure to news and staying in a supportive social circle when stuck in such situations. Here are a few steps you should follow: 1. Limit news exposure: Set boundaries on news consumption to avoid excessive exposure.2. Stay informed, not overwhelmed: Focus on credible sources and updates rather than constant coverage.3. Practice self-care: Engage in activities that promote relaxation and stress reduction, such as exercise, meditation, or hobbies.4. Social support: Connect with loved ones, friends, or support groups to share feelings and concerns.5. Grounding techniques: Use mindfulness exercises, deep breathing, or physical activity to stay present and focused.Coping Strategies For Families And ChildrenIf you are someone who resides with the elderly and children, Dr Saraswat recommends having an open discussion with them on the current situation. "Encourage honest discussions about feelings and concerns," he said. Moreover, you must provide reassurance and comfort to them. To avoid anxieties, it is also advised to maintain regular routines and activities to provide a sense of stability. You should also acknowledge and validate children's feelings, helping them process emotions. Moreover, monitor and limit children's exposure to news and media coverage.Differentiating Normal Stress Responses from Serious Mental Health Concerns1. Normal stress responses: Anxiety, worry, and fear are common reactions to stressful situations.2. Signs of more serious concerns: Persistent symptoms, such as intrusive thoughts, nightmares, or avoidance behaviours, may indicate PTSD or other mental health concerns.3. Panic disorders: Recurring panic attacks, persistent fear of having attacks, or avoidance behaviours may indicate a panic disorder.4. Seek professional help: If symptoms persist or interfere with daily life, consult a mental health professional for guidance and support.

amid rising indo-pak tensions, here's how you can manage your anxiety

Tanya Dutt

This Game-Changing Drug Could Finally Bring Your 'Bad' Cholesterol Under Control; 10 Natural Hacks To Follow

Nutrition

10 Egg Health Myths We Thought Were True—But Aren't

10 egg health myths we thought were true—but aren't

Health News

Does Chemotherapy Cause Dementia?

does chemotherapy cause dementia?

couscous is more processed than you think—but it's still healthy. here's why

Heart disease is still the number one killer worldwide, and "bad" cholesterol – or LDL (low-density lipoprotein) – is at the heart of this health epidemic. Even after decades of depending on statins to manage high cholesterol, millions still have perilously high levels of LDL. But a revolutionary combination of drugs could finally bring hope to those who are fighting to keep their <span>heart health</span> in check, even with standard treatment.

A new cholesterol-lowering drug is a game-changer. A new two-drug combination—obicetrapib plus ezetimibe—has proven dramatic impacts on lowering <span>LDL cholesterol</span> in people who have high LDL levels even after they are on statins. In a new Phase 3 clinical trial from the Cleveland Clinic, this two-drug combination delivered a staggering 49% decrease in LDL cholesterol after only 12 weeks.

The results were presented at the European Atherosclerosis Society congress in Glasgow and simultaneously published in The Lancet, lending authority to what is potentially a large change in the treatment of cardiovascular disease. The trial enrolled 407 patients with a mean age of 68, all with LDL above the American Heart Association's suggested cutoff of 70 mg/dL for patients at high risk. Even while continuing their usual cholesterol-lowering medications, only those who received the new combo pill experienced such dramatic reductions in LDL.

Dr. Ashish Sarraju, the lead author and preventive cardiologist, stressed the need for increasing choices for patients. "In patients at higher risk, you want to lower LDL as soon as possible and maintain it as long as possible," he said. For those who have already had a heart attack or stroke—or are at high risk—this therapy may provide the aggressive lowering of cholesterol that statins alone cannot provide.

<h2>Why Statins Alone Are Not Enough Any More?</h2>

Statins have been the front-line therapy for high cholesterol for many years but have their weaknesses. They are intolerable to some patients, and in others, they fail to produce the LDL falls required to avoid repeat cardiovascular events. Even high-intensity statin therapy proves inadequate in those at highest risk.

Dr. Corey Bradley of Columbia University observes, "Many people have such a high LDL they will require multiple agents to control it." That's where the obicetrapib-ezetimibe combination steps in—providing a synergistic solution for patients who have reached a wall with conventional meds.

It’s worth noting that not all drugs in the same category have shown benefits in the past. CETP inhibitors, a class of drugs that includes obicetrapib, have previously failed to demonstrate protection against heart attacks or strokes in clinical trials. However, experts remain cautiously optimistic about this new formulation.

Dr. Robert Rosenson of Mount Sinai Health System said, "Some of the drugs in this class have not prevented strokes or heart attacks. But I am hopeful cautiously." NewAmsterdam Pharma, the Dutch firm behind obicetrapib, is now carrying out additional trials to see if this drug not only reduces LDL but also major cardiovascular events.

NewAmsterdam Pharma has revealed it will sit down with the U.S. Food and Drug Administration this year to talk about regulatory avenues for approval. Assuming everything goes according to plan, the new combination may soon be accessible to millions of patients in the U.S. and internationally.

<h2>Ways to Lower Your Cholesterol Naturally</h2>

Though new drugs such as this provide a hopeful answer for at-risk patients, they don't eliminate the necessity for ongoing lifestyle changes. The CDC says that only 20% of people can control their LDL levels with lifestyle changes alone. Nevertheless, every little bit helps—particularly when used in conjunction with medication.

Low cholesterol doesn't always mean taking medication—there are potent, natural lifestyle modifications that can do wonders to your lipid profile and heart health. Below are ways you can lower <span>bad cholesterol</span> (LDL) and increase good cholesterol (HDL) with realistic, long-term changes: 

Emphasize a diet high in soluble fiber, healthy fat, and plant foods. Eat oats, legumes, apples and berries, vegetables, and whole grains. Replace saturated fat in red meat and whole milk dairy with heart-healthy fats like those of avocados, nuts, seeds, and olive oil. Eliminate trans fats altogether—they increase LDL and decrease HDL.

<h4>Get Moving with Regular Exercise</h4>

Physical activity tends to increase good cholesterol and decrease bad cholesterol. Be as active as possible throughout the week; aim for 150 minutes of brisk walking, cycling, or swimming per week. Even small activities like taking the stairs or taking the short walk after a meal can pay off in the long run.

Losing a few pounds will improve <span>cholesterol levels</span>. Being overweight helps to raise LDL levels and lower HDL. Practice mindful eating, portioning, and consistent activity to induce a calorie deficit that allows for gradual, healthy weight loss.

Smoking injures the blood vessels, decreases good cholesterol, and places one at an increased risk for heart disease. After quitting in weeks, one starts to recover in terms of HDL cholesterol, and a year later, the risk for heart disease lessens significantly. 

Even if moderate drinking contributes a little positive effect on the level of HDL, more drinking raises both total cholesterol and triglycerides. If you drink, consume it in moderate amounts—limited to one alcoholic beverage per day for women and two for men.

Chronic stress can indirectly influence cholesterol by encouraging unhealthy habits such as overeating or smoking. Practice stress-reducing activities such as yoga, deep breathing, meditation, or simply taking a walk in nature to promote heart health.

<h4>Select Plant Sterols and Supplements Carefully</h4>

Some plant compounds such as sterols and stanols can inhibit the absorption of cholesterol. You can get these in fortified foods and natural supplements. Always consult a healthcare professional before taking any new supplement.

The release of this new combination therapy represents a possible paradigm shift in cholesterol treatment—especially among aging populations, genetically predisposed individuals, and those with underlying cardiovascular disease. If FDA-approved and integrated into clinical practice, this combination drug may have a profound impact on reducing the global incidence of heart disease.

These whole-body, evidence-based strategies provide a map to naturally enhance cholesterol and heart health—without resorting solely to prescription drugs.

heart health

bad cholesterol

ldl cholesterol

cholesterol levels

artery blockage

cholesterol and diet

high cholesterol risks

Heart disease is still the number one killer worldwide, and "bad" cholesterol – or LDL (low-density lipoprotein) – is at the heart of this health epidemic. Even after decades of depending on statins to manage high cholesterol, millions still have perilously high levels of LDL. But a revolutionary combination of drugs could finally bring hope to those who are fighting to keep their heart health in check, even with standard treatment.A new cholesterol-lowering drug is a game-changer. A new two-drug combination—obicetrapib plus ezetimibe—has proven dramatic impacts on lowering LDL cholesterol in people who have high LDL levels even after they are on statins. In a new Phase 3 clinical trial from the Cleveland Clinic, this two-drug combination delivered a staggering 49% decrease in LDL cholesterol after only 12 weeks.The results were presented at the European Atherosclerosis Society congress in Glasgow and simultaneously published in The Lancet, lending authority to what is potentially a large change in the treatment of cardiovascular disease. The trial enrolled 407 patients with a mean age of 68, all with LDL above the American Heart Association's suggested cutoff of 70 mg/dL for patients at high risk. Even while continuing their usual cholesterol-lowering medications, only those who received the new combo pill experienced such dramatic reductions in LDL.Dr. Ashish Sarraju, the lead author and preventive cardiologist, stressed the need for increasing choices for patients. "In patients at higher risk, you want to lower LDL as soon as possible and maintain it as long as possible," he said. For those who have already had a heart attack or stroke—or are at high risk—this therapy may provide the aggressive lowering of cholesterol that statins alone cannot provide.Why Statins Alone Are Not Enough Any More?Statins have been the front-line therapy for high cholesterol for many years but have their weaknesses. They are intolerable to some patients, and in others, they fail to produce the LDL falls required to avoid repeat cardiovascular events. Even high-intensity statin therapy proves inadequate in those at highest risk.Dr. Corey Bradley of Columbia University observes, "Many people have such a high LDL they will require multiple agents to control it." That's where the obicetrapib-ezetimibe combination steps in—providing a synergistic solution for patients who have reached a wall with conventional meds.What Makes This Drug Different?It’s worth noting that not all drugs in the same category have shown benefits in the past. CETP inhibitors, a class of drugs that includes obicetrapib, have previously failed to demonstrate protection against heart attacks or strokes in clinical trials. However, experts remain cautiously optimistic about this new formulation.Dr. Robert Rosenson of Mount Sinai Health System said, "Some of the drugs in this class have not prevented strokes or heart attacks. But I am hopeful cautiously." NewAmsterdam Pharma, the Dutch firm behind obicetrapib, is now carrying out additional trials to see if this drug not only reduces LDL but also major cardiovascular events.NewAmsterdam Pharma has revealed it will sit down with the U.S. Food and Drug Administration this year to talk about regulatory avenues for approval. Assuming everything goes according to plan, the new combination may soon be accessible to millions of patients in the U.S. and internationally.Ways to Lower Your Cholesterol NaturallyThough new drugs such as this provide a hopeful answer for at-risk patients, they don't eliminate the necessity for ongoing lifestyle changes. The CDC says that only 20% of people can control their LDL levels with lifestyle changes alone. Nevertheless, every little bit helps—particularly when used in conjunction with medication.Low cholesterol doesn't always mean taking medication—there are potent, natural lifestyle modifications that can do wonders to your lipid profile and heart health. Below are ways you can lower bad cholesterol (LDL) and increase good cholesterol (HDL) with realistic, long-term changes: Follow a Heart-Healthy DietEmphasize a diet high in soluble fiber, healthy fat, and plant foods. Eat oats, legumes, apples and berries, vegetables, and whole grains. Replace saturated fat in red meat and whole milk dairy with heart-healthy fats like those of avocados, nuts, seeds, and olive oil. Eliminate trans fats altogether—they increase LDL and decrease HDL.Get Moving with Regular ExercisePhysical activity tends to increase good cholesterol and decrease bad cholesterol. Be as active as possible throughout the week; aim for 150 minutes of brisk walking, cycling, or swimming per week. Even small activities like taking the stairs or taking the short walk after a meal can pay off in the long run.Maintain a Healthy WeightLosing a few pounds will improve cholesterol levels. Being overweight helps to raise LDL levels and lower HDL. Practice mindful eating, portioning, and consistent activity to induce a calorie deficit that allows for gradual, healthy weight loss.Quit SmokingSmoking injures the blood vessels, decreases good cholesterol, and places one at an increased risk for heart disease. After quitting in weeks, one starts to recover in terms of HDL cholesterol, and a year later, the risk for heart disease lessens significantly. Limit Alcohol IntakeEven if moderate drinking contributes a little positive effect on the level of HDL, more drinking raises both total cholesterol and triglycerides. If you drink, consume it in moderate amounts—limited to one alcoholic beverage per day for women and two for men.Manage Stress EffectivelyChronic stress can indirectly influence cholesterol by encouraging unhealthy habits such as overeating or smoking. Practice stress-reducing activities such as yoga, deep breathing, meditation, or simply taking a walk in nature to promote heart health.Select Plant Sterols and Supplements CarefullySome plant compounds such as sterols and stanols can inhibit the absorption of cholesterol. You can get these in fortified foods and natural supplements. Always consult a healthcare professional before taking any new supplement.The release of this new combination therapy represents a possible paradigm shift in cholesterol treatment—especially among aging populations, genetically predisposed individuals, and those with underlying cardiovascular disease. If FDA-approved and integrated into clinical practice, this combination drug may have a profound impact on reducing the global incidence of heart disease.These whole-body, evidence-based strategies provide a map to naturally enhance cholesterol and heart health—without resorting solely to prescription drugs.

new game-changing drug could bring your 'bad' cholesterol under control; 10 natural hacks to follow

Cancer Before Age 50 Is On The Rise, New Study Lists Which Types

World Ovarian Cancer Day 2025: Theme, Significance, and History

world ovarian cancer day 2025: theme, significance, and history

Women Beware! Your Everyday Beauty Products May Have Cancer-Causing Chemicals

women beware! your everyday beauty products may have cancer-causing chemicals

<span>Cancer</span> is often seen as a disease that primarily affects older individuals. After all, the average age of diagnosis is 66, and the risk of developing cancer rises steadily with age. However, a disturbing trend is emerging: more young adults are being diagnosed with cancer before the age of 50. This article explores this shift, its potential causes, and the types of cancers that are rising in younger populations.

In the United States, cancer is diagnosed in fewer than 25 out of every 100,000 people under the age of 20, and it accounts for just 1 percent of all cancer diagnoses, according to the National Cancer Institute (NCI). By the time individuals reach the ages of 45 to 49, the incidence of cancer jumps to about 350 cases per 100,000 people. This rate almost triples to 1,000 cases per 100,000 in people 60 and above. Nevertheless, researchers now notice a concerning trend—a rise in the number of cancer cases being diagnosed in young adults, especially those below 50.

A new research by the NCI shows an in-depth analysis of early-onset cancers in the US. The research, which spanned over 2 million cases diagnosed between 2010 and 2019, revealed substantial increases in certain forms of cancer among younger individuals. Breast, colorectal, kidney, and uterine cancers were identified as the top drivers of this increase. Of the 33 cancers examined, 14 had increasing rates in at least one younger age group, with 63% of these early-onset cancers being in women.

The NCI's report compared cancer incidence in 2019 with what could have been anticipated from the rates in 2010. The results are worrisome:

<strong>Breast Cancer</strong>: The biggest proportion of the increase was seen in breast cancer, with approximately 4,800 extra cases in young adults compared to what could have been anticipated.

<strong>Colorectal Cancer</strong>: There were 2,000 more than anticipated cases of colorectal cancer.

<strong>Kidney Cancer</strong>: 1,800 more cases of kidney cancer were diagnosed.

<strong>Uterine Cancer</strong>: Uterine cancer diagnoses went up by 1,200 cases.

Interestingly, even as the diagnosis is on the increase, the mortality rates for the majority of cancers among young people have not actually increased. There were, however, sharp increases in the mortality rates for colorectal, uterine, and testicular cancers among the young population.

The causes of this rise in early-onset cancer are multifaceted and complex. Although more study is required, a number of theories have been put forward by specialists in the field:

Obesity: Obesity has been associated with a heightened risk of various cancers, including uterine and colorectal cancers, for many years. As obesity continues to increase, it could account for some of the rises in cancer diagnoses among young individuals.

Advances in Detection of Cancer: Enhanced screening techniques and shifts in guidelines for early detection may be contributing. These advances have resulted in increasing numbers of cancers being detected at an earlier stage, which may be contributing to the increase in diagnoses.

Delayed Childbearing: For women, delayed childbearing is linked with an increased risk of breast cancer. Pregnancy and lactation have been shown to decrease the risk of breast cancer, therefore delayed pregnancies might be adding to the increase in cases among younger women.

Environmental and Lifestyle Factors: Greater exposure to carcinogens, either through pollution, chemicals, or lifestyle choices, may also be affecting cancer rates among young people.

<h2>What Kinds of Cancer Are Increasing?</h2>

While the rate of cancer for some cancers in older individuals is decreasing, young people are experiencing more cases of certain cancers. The greatest increases have been seen in the following:

This cancer is among the most prevalent cancers of younger women, especially those under the age of 50. A concerning trend that has been seen is an increase in more aggressive subtypes of breast cancer, including triple-negative and HER2-positive breast cancers. These cancers are harder to treat and have poorer prognoses.

Previously viewed as a disease of predominantly older individuals, colorectal cancer is becoming more prevalent among young people. Early-onset colorectal cancer is specifically of concern because it is often diagnosed at later stages when it is more difficult to treat.

This form of cancer is increasingly found in younger women. Similar to colorectal cancer, the increasing uterine cancer may be a result of the escalating obesity epidemic.

Kidney cancer diagnoses have similarly increased in young adults. While the causes of this are unknown, it is believed that obesity and other lifestyle-related issues may be to blame.

<h2>Are Some Cancers Are Decreasing Too?</h2>

While there has been an increase in early-onset cancers, it must be added that cancer incidence is falling for various forms in younger age groups. The most significant falls have been observed in lung cancer and prostate cancer.

Lung Cancer: The decrease in lung cancer is, in large part, due to the substantial reduction in cigarette smoking prevalence during the last decades. This has resulted in a commensurate reduction in the incidence of young adults with lung cancer.

Prostate Cancer: The reduction in prostate cancer incidence can be attributed to revised screening recommendations that discourage the routine use of prostate-specific antigen (PSA) testing in young men. This has lowered the rate of unnecessary diagnoses and treatments.

<h2>How Are Early-Onset Cancers Different?</h2>

The most glaring distinction between early-onset cancers and those that are diagnosed later in life is age. Yet, the aggressiveness of some cancers, particularly breast cancer, is a major consideration. Younger patients tend to have more aggressive types of cancer, which tend to be treated with more aggressive and invasive therapies.

In breast cancer, for instance, younger women will tend to carry genetically caused cancers, like the ones related to BRCA mutation. But again, these genes only explain only 20% of early-onset breast cancer, which points to other genetic or environmental exposures as well. 

<h2>Can Early-Onset Cancer Be Prevented?</h2>

Although it is not possible for anybody to avoid the risk of cancer entirely, some lifestyle choices will minimize the chance of cancer occurrence. According to experts, they include the following:

<ul><li>Physical activity can lower the risk of developing many cancers, including breast and colon cancer.</li><li>A balanced diet with plenty of fruits, vegetables, and whole grains can reduce the risk of cancer. Reducing processed foods and alcohol consumption is also helpful.</li><li>Smoking is a major cause of cancer, especially lung cancer. Stopping smoking at any age can lower the risk substantially.</li><li>If there is a family history of cancer, it is critical to bring this up with your physician. Genetic counseling and ongoing screening may help detect cancers at an earlier stage, when they are more treatable.</li><li>Early awareness of cancer signs and symptoms is key. Regular check-ups and screenings, like mammograms and colonoscopies, can detect cancers before they become problematic, enhancing the potential for effective treatment.</li></ul>

Although the increase in early-onset cancers is distressing, it is also an urgent call for more research. Researchers need to work towards establishing the root cause of this surge, especially for cancers such as breast, colorectal, and uterine cancers. Through the discovery of the drivers behind these trends, we can then create better prevention methods and treatment options, improving the prognosis of younger cancer patients.

The growing number of cancers occurring before the age of 50 is an important public health issue that must be addressed now. Although certain cancers are decreasing, others are increasing, and it is imperative to keep monitoring and studying these trends to promote a healthier tomorrow for everyone.

Cancer is often seen as a disease that primarily affects older individuals. After all, the average age of diagnosis is 66, and the risk of developing cancer rises steadily with age. However, a disturbing trend is emerging: more young adults are being diagnosed with cancer before the age of 50. This article explores this shift, its potential causes, and the types of cancers that are rising in younger populations.In the United States, cancer is diagnosed in fewer than 25 out of every 100,000 people under the age of 20, and it accounts for just 1 percent of all cancer diagnoses, according to the National Cancer Institute (NCI). By the time individuals reach the ages of 45 to 49, the incidence of cancer jumps to about 350 cases per 100,000 people. This rate almost triples to 1,000 cases per 100,000 in people 60 and above. Nevertheless, researchers now notice a concerning trend—a rise in the number of cancer cases being diagnosed in young adults, especially those below 50.A new research by the NCI shows an in-depth analysis of early-onset cancers in the US. The research, which spanned over 2 million cases diagnosed between 2010 and 2019, revealed substantial increases in certain forms of cancer among younger individuals. Breast, colorectal, kidney, and uterine cancers were identified as the top drivers of this increase. Of the 33 cancers examined, 14 had increasing rates in at least one younger age group, with 63% of these early-onset cancers being in women.The NCI's report compared cancer incidence in 2019 with what could have been anticipated from the rates in 2010. The results are worrisome:Breast Cancer: The biggest proportion of the increase was seen in breast cancer, with approximately 4,800 extra cases in young adults compared to what could have been anticipated.Colorectal Cancer: There were 2,000 more than anticipated cases of colorectal cancer.Kidney Cancer: 1,800 more cases of kidney cancer were diagnosed.Uterine Cancer: Uterine cancer diagnoses went up by 1,200 cases.Interestingly, even as the diagnosis is on the increase, the mortality rates for the majority of cancers among young people have not actually increased. There were, however, sharp increases in the mortality rates for colorectal, uterine, and testicular cancers among the young population.Why Is This Happening?The causes of this rise in early-onset cancer are multifaceted and complex. Although more study is required, a number of theories have been put forward by specialists in the field:Obesity: Obesity has been associated with a heightened risk of various cancers, including uterine and colorectal cancers, for many years. As obesity continues to increase, it could account for some of the rises in cancer diagnoses among young individuals.Advances in Detection of Cancer: Enhanced screening techniques and shifts in guidelines for early detection may be contributing. These advances have resulted in increasing numbers of cancers being detected at an earlier stage, which may be contributing to the increase in diagnoses.Delayed Childbearing: For women, delayed childbearing is linked with an increased risk of breast cancer. Pregnancy and lactation have been shown to decrease the risk of breast cancer, therefore delayed pregnancies might be adding to the increase in cases among younger women.Environmental and Lifestyle Factors: Greater exposure to carcinogens, either through pollution, chemicals, or lifestyle choices, may also be affecting cancer rates among young people.What Kinds of Cancer Are Increasing?While the rate of cancer for some cancers in older individuals is decreasing, young people are experiencing more cases of certain cancers. The greatest increases have been seen in the following:Breast CancerThis cancer is among the most prevalent cancers of younger women, especially those under the age of 50. A concerning trend that has been seen is an increase in more aggressive subtypes of breast cancer, including triple-negative and HER2-positive breast cancers. These cancers are harder to treat and have poorer prognoses.Colorectal CancerPreviously viewed as a disease of predominantly older individuals, colorectal cancer is becoming more prevalent among young people. Early-onset colorectal cancer is specifically of concern because it is often diagnosed at later stages when it is more difficult to treat.Uterine CancerThis form of cancer is increasingly found in younger women. Similar to colorectal cancer, the increasing uterine cancer may be a result of the escalating obesity epidemic.Kidney CancerKidney cancer diagnoses have similarly increased in young adults. While the causes of this are unknown, it is believed that obesity and other lifestyle-related issues may be to blame.Are Some Cancers Are Decreasing Too?While there has been an increase in early-onset cancers, it must be added that cancer incidence is falling for various forms in younger age groups. The most significant falls have been observed in lung cancer and prostate cancer.Lung Cancer: The decrease in lung cancer is, in large part, due to the substantial reduction in cigarette smoking prevalence during the last decades. This has resulted in a commensurate reduction in the incidence of young adults with lung cancer.Prostate Cancer: The reduction in prostate cancer incidence can be attributed to revised screening recommendations that discourage the routine use of prostate-specific antigen (PSA) testing in young men. This has lowered the rate of unnecessary diagnoses and treatments.How Are Early-Onset Cancers Different?The most glaring distinction between early-onset cancers and those that are diagnosed later in life is age. Yet, the aggressiveness of some cancers, particularly breast cancer, is a major consideration. Younger patients tend to have more aggressive types of cancer, which tend to be treated with more aggressive and invasive therapies.In breast cancer, for instance, younger women will tend to carry genetically caused cancers, like the ones related to BRCA mutation. But again, these genes only explain only 20% of early-onset breast cancer, which points to other genetic or environmental exposures as well. Can Early-Onset Cancer Be Prevented?Although it is not possible for anybody to avoid the risk of cancer entirely, some lifestyle choices will minimize the chance of cancer occurrence. According to experts, they include the following:Physical activity can lower the risk of developing many cancers, including breast and colon cancer.A balanced diet with plenty of fruits, vegetables, and whole grains can reduce the risk of cancer. Reducing processed foods and alcohol consumption is also helpful.Smoking is a major cause of cancer, especially lung cancer. Stopping smoking at any age can lower the risk substantially.If there is a family history of cancer, it is critical to bring this up with your physician. Genetic counseling and ongoing screening may help detect cancers at an earlier stage, when they are more treatable.Early awareness of cancer signs and symptoms is key. Regular check-ups and screenings, like mammograms and colonoscopies, can detect cancers before they become problematic, enhancing the potential for effective treatment.Although the increase in early-onset cancers is distressing, it is also an urgent call for more research. Researchers need to work towards establishing the root cause of this surge, especially for cancers such as breast, colorectal, and uterine cancers. Through the discovery of the drivers behind these trends, we can then create better prevention methods and treatment options, improving the prognosis of younger cancer patients.The growing number of cancers occurring before the age of 50 is an important public health issue that must be addressed now. Although certain cancers are decreasing, others are increasing, and it is imperative to keep monitoring and studying these trends to promote a healthier tomorrow for everyone.

Colon Cancer Is The Third Most Common Cancer In Men: Symptoms, Treatment And Prevention

Quick Stories

Amid Rising Indo-Pak Tensions, Here's How You Can Manage Your Anxiety

New Game-Changing Drug Could Bring Your 'Bad' Cholesterol Under Control; 10 Natural Hacks To Follow

Cancer Before Age 50 Is On The Rise, New Study Lists Which Types

Health Conditions A-Z

Amid Rising Indo-Pak Tensions, Here's How You Can Manage Your Anxiety

Couscous Is More Processed Than You Think—But It's Still Healthy. Here's Why

New Game-Changing Drug Could Bring Your 'Bad' Cholesterol Under Control; 10 Natural Hacks To Follow