When it comes to cancer screenings, women generally keep themselves in check. Pap smears pick up cervical cancer early, mammograms detect breast cancer, and colonoscopies are routine as we get older. But ovarian cancer—although the fifth-deadliest among women—frequently goes largely unnoticed.More than 22,000 women a year are diagnosed with ovarian cancer in the U.S., and more than 12,000 die of it, reports the American Cancer Society. The true tragedy? The condition is extremely hard to diagnose during early stages.No test screens for ovarian cancer routinely. The widely referred to CA 125 blood test is not accurate enough for making early diagnoses because benign conditions cause a rise in CA 125, too. Therefore, over 80% of ovarian cancers are diagnosed late in their stage, when the process of treatment becomes more intricate and survival diminishes. Ovarian Cancer Symptoms They OverlookedMatt Cauli, aka The Dedicated Caregiver took to Instagram to share his wife's journey, he had no idea the small, apparently unrelated symptoms his wife had would be precursors to ovarian cancer. Overnight, their life changed after she developed two massive strokes—a heart-breaking result of late-stage, undiagnosed ovarian cancer.The strokes put Matt's wife into bed and paralyzed her on the left side. Matt is now balancing caregiving duties for his wife and their young son. As his story receives attention on Instagram, Matt's viral video has resonated with millions of families everywhere.In the tearful video, Matt speaks about the three symptoms they didn't know were ovarian cancer—a harsh reminder of how easily symptoms can be overlooked, dismissed, or misdiagnosed:1. Random Swollen Joints"One time it was her elbow. Then her knee," Matt explained in the video. "They tested her for Lyme disease, but it came back negative."Suffy joints are hardly ever associated with ovarian cancer, and so are almost always mislaid as being caused by autoimmune diseases or trauma. Still, cancerous inflammation may arise in unpredictable manifestations. Some individuals with ovarian cancer experience fluid retention or inflammatory responses, which could manifest as local swelling of the joints.Matt's message is unequivocal: if something does not feel right in the body—and will not resolve—don't dismiss it.2. Abnormal Menstrual Changes"She had this heavy, clotty period about a month before her stroke," Matt disclosed. "It just wasn't normal."Heavy, irregular, or abnormally clotty menstrual bleeding is usually caused by hormonal imbalance, fibroids, or perimenopause. But when the symptoms suddenly occur and are unusual, they warrant immediate medical care.Physicians indicate abnormal bleeding, particularly when accompanied by bloating or pelvic tenderness, might be the body's response to hidden reproductive system problems, such as ovarian cancer. Again, however, too frequently these variations are accepted or downplayed—particularly in busy women attempting to juggle work and motherhood.3. Fatigue"I have to laugh at this one," Matt says with gallows humor, "because what young mom isn't tired?It's a feeling many women can identify with. Exhaustion is almost worn as a badge of honor in our busy world. But ongoing, unexplained exhaustion—the kind that doesn't subside with rest or isn't related to lifestyle—can be one of the first indications of cancer.In ovarian cancer, this kind of fatigue can have its roots in anemia, inflammation, or even the increased metabolic needs of a developing tumor. But due to how universal fatigue is, particularly among mothers, it commonly goes unnoticed and is blamed on burnout. Why Ovarian Cancer Is Still So Dangerous?One of the major difficulties with diagnosing ovarian cancer is that its early signs are similar to very normal and benign conditions: constipation, bloating, back pain, and being too full too quickly after eating. Since there is no one test or scan to have faith in, most women remain undiagnosed until the cancer has spread beyond the ovaries.And while genetic mutations such as BRCA1, BRCA2, and Lynch syndrome are responsible for about 20% of ovarian cancer, that still leaves a high percentage with no hereditary risk, making education all the more important.Even with the bleak statistics, there is cause for optimism on the horizon. Previously, the choices were essentially surgery and chemotherapy. But today, there are over 1,350 ongoing clinical trials in ovarian cancer, including vaccine-based treatments to prevent recurrence and enhance long-term survival.Scientists are also looking at targeted treatments and immunotherapy to customize treatment to the specific tumor biology of each individual patient. These advances could provide women with improved chances in the years to come—but early detection is still the first and most important step.Perhaps one day there'll be a simple blood test, or an annual screening, for ovarian cancer. But you are the only person who knows your body. And if something feels wrong—persisting bloating, unusual cycles, sudden tiredness—talk. Demand to know.As Matt expresses it, "From what I know… Ovarian cancer is very hard to detect. But you know your body best. So talk with your doctor if you think something's going on." Since the sooner it gets detected, the better the chances are. And when lives are at stake, awareness is everything.