Health and Me

Tanya Dutt

Why Its Important To Check The Expiry Date On Your Pregnancy Test?

If you're trying to conceive or even think you might be pregnant, the wait and anticipation for a <span>pregnancy</span> test can be nerve-wracking—hope, worry, excitement, or fear all in one little plastic stick but before you rip open that foil package, there's something important you may be forgetting: the expiration date.

Yes, pregnancy kits do have expiry dates. And taking one which has passed that date may cause false results. This article touches on why checking that date on the kit first is important before you test, how pregnancy kits work, and what dangers such expired kits possess. Supported by expert opinion and scientific knowledge, this guide endeavors to equip you with the knowledge you require for making informed reproductive health choices.

Home pregnancy tests detect the human chorionic gonadotropin (hCG) hormone in your urine, which your body begins making shortly after the fertilized egg implants in your uterus. The test sticks use special antibodies with chemicals that have been treated to respond to hCG and report a positive finding—usually lines, plus symbols, or messages on a display.

With time, though, the delicate components break down. After the test has reached or exceeded its expiration date, the chemical reagents can no longer act dependably. That is, the test might not register hCG when it's actually there, providing you with a false negative result, or—much less often—report a false positive based on poor chemical reactions. 

<h2>What Happens When a Pregnancy Test Expires?</h2>

The date of expiration on a pregnancy test is not merely a courtesy. Companies test their products extensively to find out how long the ingredients will be stable and consistent under normal storage conditions. A pregnancy test will usually be effective for one to three years from the date of manufacture.

Once that time has passed, the antibodies that are employed to identify hCG start to weaken. This weakening is subtle but significant—making the test incapable of giving accurate results. The older the test, the greater the likelihood that you'll leave with a result that doesn't accurately represent your pregnancy status.

Just as important as the expiration date is how the test is stored. According to healthcare professionals, the performance of a pregnancy test can deteriorate even before its listed expiry if it’s stored improperly.

Avoid exposing the test to heat, moisture, or direct sunlight. A bathroom medicine cabinet, while convenient, is often not ideal due to the humidity from showers and temperature fluctuations. Instead, keep pregnancy tests in a cool, dry place, and avoid unwrapping individual tests until you’re ready to use them. Unsealing the protective foil can introduce air and moisture that degrade the chemicals faster.

<h2>How to Identify an Expired Test?</h2>

Always inspect the outer package and test wrapper individually for a printed expiration date. If it is absent or smudged, better not take a risk. Also, beware of buying tests from third-party retailers or online stores where expired stock may go unnoticed.

It's also good to know that even tests just purchased can be old inventory. If you've had a test kit in your bathroom drawer for more than one year, verify the printed date before you use it.

Technically, it's possible for an outdated pregnancy test to return a correct result—but it's not reliable. The odds of false negatives grow more sharply with time, which can cause confusion, worry, and delay in obtaining critical prenatal care.

Under FDA recommendations, most erroneous results from past-due tests are likely to be false negatives. This may lead one to continue habits or drugs that are not best practiced in early pregnancy—or lose the opportunity to start early prenatal supplements or tests.

The effect of depending on an out-of-date pregnancy test isn't only medical—it's psychological as well. Inaccurate results can induce undue distress, confusion, or early rejoicing. Even worse, they may stall time-critical health choices like verifying the pregnancy through a physician, making blood work appointments, or starting lifestyle modifications to facilitate a healthy pregnancy.

In medical situations where time is of the essence—like watching over high-risk pregnancies or starting specific treatments—true, timely information is paramount.

<h2>Best Practices for Taking a Home Pregnancy Test</h2>

To ensure most accurate results, follow these steps:

<ul><li>Inspect the expiration date before taking any test, even if the package appears new.</li><li>Take first-morning urine when hCG is most concentrated in the urine.</li><li>Wait until the first day of your missed period to take the test; testing earlier riskily produces a false negative.</li><li>Take directions exactly, including timing when to read the results.</li><li>Dispose of unused tests properly, in a dry, cool environment and in their original sealed package.</li></ul>

<h2>How Expired Pregnancy Tests Impact Health and Results?</h2>

Taking an expired pregnancy test can result in incorrect results, which might lead to undue confusion or undue delay in taking the appropriate next step. Here's what you should know regarding the effectiveness of an expired pregnancy test:

<h4>Increased Chance of False Negatives</h4>

One of the most significant problems with using an outdated pregnancy test is the increased likelihood of getting a false negative result. This is where the test will show that you're not pregnant when you actually are. This is due to the chemical compounds, especially the antibodies employed to identify hCG, breaking down over time, thus it becomes hard for the test to give a true result.

Pregnancy tests detect human Chorionic Gonadotropin (hCG), a hormone that is formed during pregnancy. After a while, the antibodies in the test, which cause a response when hCG is present, become weakened. So even if you are pregnant, the test may fail to measure the hormone at a level that is high enough.

As per the U.S. Food and Drug Administration (FDA), expired pregnancy tests tend to give false negatives rather than false positives. A false positive may also occur but is less so with expired tests.

The reliability of a pregnancy test is also affected by the way it's stored. Incorrect storage, for example exposure to sunlight, humidity, or heat, causes the components to degrade faster and results in more opportunities for getting incorrect results prior to reaching expiration. 

Using an expired test not only reduces the likelihood of getting an accurate result but also wastes your time and money. It's best to check the expiration date before using the test and, if expired, purchase a new one for peace of mind and more reliable results.

The effect of depending on an out-of-date pregnancy test isn't only medical—it's psychological as well. Inaccurate results can induce undue distress, confusion, or early rejoicing.

Though home pregnancy tests are an efficient and convenient means of early pregnancy detection, their accuracy relies on a number of major factors, foremost among them their expiration date. Testing with one that has expired may cause emotional distress and delay medical attention at a time when it's needed most.

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If you're trying to conceive or even think you might be pregnant, the wait and anticipation for a pregnancy test can be nerve-wracking—hope, worry, excitement, or fear all in one little plastic stick but before you rip open that foil package, there's something important you may be forgetting: the expiration date.Yes, pregnancy kits do have expiry dates. And taking one which has passed that date may cause false results. This article touches on why checking that date on the kit first is important before you test, how pregnancy kits work, and what dangers such expired kits possess. Supported by expert opinion and scientific knowledge, this guide endeavors to equip you with the knowledge you require for making informed reproductive health choices.Home pregnancy tests detect the human chorionic gonadotropin (hCG) hormone in your urine, which your body begins making shortly after the fertilized egg implants in your uterus. The test sticks use special antibodies with chemicals that have been treated to respond to hCG and report a positive finding—usually lines, plus symbols, or messages on a display.With time, though, the delicate components break down. After the test has reached or exceeded its expiration date, the chemical reagents can no longer act dependably. That is, the test might not register hCG when it's actually there, providing you with a false negative result, or—much less often—report a false positive based on poor chemical reactions. What Happens When a Pregnancy Test Expires?The date of expiration on a pregnancy test is not merely a courtesy. Companies test their products extensively to find out how long the ingredients will be stable and consistent under normal storage conditions. A pregnancy test will usually be effective for one to three years from the date of manufacture.Once that time has passed, the antibodies that are employed to identify hCG start to weaken. This weakening is subtle but significant—making the test incapable of giving accurate results. The older the test, the greater the likelihood that you'll leave with a result that doesn't accurately represent your pregnancy status.Just as important as the expiration date is how the test is stored. According to healthcare professionals, the performance of a pregnancy test can deteriorate even before its listed expiry if it’s stored improperly.Avoid exposing the test to heat, moisture, or direct sunlight. A bathroom medicine cabinet, while convenient, is often not ideal due to the humidity from showers and temperature fluctuations. Instead, keep pregnancy tests in a cool, dry place, and avoid unwrapping individual tests until you’re ready to use them. Unsealing the protective foil can introduce air and moisture that degrade the chemicals faster.How to Identify an Expired Test?Always inspect the outer package and test wrapper individually for a printed expiration date. If it is absent or smudged, better not take a risk. Also, beware of buying tests from third-party retailers or online stores where expired stock may go unnoticed.It's also good to know that even tests just purchased can be old inventory. If you've had a test kit in your bathroom drawer for more than one year, verify the printed date before you use it.Can You Trust an Expired Test?Technically, it's possible for an outdated pregnancy test to return a correct result—but it's not reliable. The odds of false negatives grow more sharply with time, which can cause confusion, worry, and delay in obtaining critical prenatal care.Under FDA recommendations, most erroneous results from past-due tests are likely to be false negatives. This may lead one to continue habits or drugs that are not best practiced in early pregnancy—or lose the opportunity to start early prenatal supplements or tests.The effect of depending on an out-of-date pregnancy test isn't only medical—it's psychological as well. Inaccurate results can induce undue distress, confusion, or early rejoicing. Even worse, they may stall time-critical health choices like verifying the pregnancy through a physician, making blood work appointments, or starting lifestyle modifications to facilitate a healthy pregnancy.In medical situations where time is of the essence—like watching over high-risk pregnancies or starting specific treatments—true, timely information is paramount.Best Practices for Taking a Home Pregnancy TestTo ensure most accurate results, follow these steps:Inspect the expiration date before taking any test, even if the package appears new.Take first-morning urine when hCG is most concentrated in the urine.Wait until the first day of your missed period to take the test; testing earlier riskily produces a false negative.Take directions exactly, including timing when to read the results.Dispose of unused tests properly, in a dry, cool environment and in their original sealed package.How Expired Pregnancy Tests Impact Health and Results?Taking an expired pregnancy test can result in incorrect results, which might lead to undue confusion or undue delay in taking the appropriate next step. Here's what you should know regarding the effectiveness of an expired pregnancy test:Increased Chance of False NegativesOne of the most significant problems with using an outdated pregnancy test is the increased likelihood of getting a false negative result. This is where the test will show that you're not pregnant when you actually are. This is due to the chemical compounds, especially the antibodies employed to identify hCG, breaking down over time, thus it becomes hard for the test to give a true result.Degraded AntibodiesPregnancy tests detect human Chorionic Gonadotropin (hCG), a hormone that is formed during pregnancy. After a while, the antibodies in the test, which cause a response when hCG is present, become weakened. So even if you are pregnant, the test may fail to measure the hormone at a level that is high enough.Health RisksAs per the U.S. Food and Drug Administration (FDA), expired pregnancy tests tend to give false negatives rather than false positives. A false positive may also occur but is less so with expired tests.Exposure to External FactorsThe reliability of a pregnancy test is also affected by the way it's stored. Incorrect storage, for example exposure to sunlight, humidity, or heat, causes the components to degrade faster and results in more opportunities for getting incorrect results prior to reaching expiration. Waste of Time and MoneyUsing an expired test not only reduces the likelihood of getting an accurate result but also wastes your time and money. It's best to check the expiration date before using the test and, if expired, purchase a new one for peace of mind and more reliable results.Emotional StressThe effect of depending on an out-of-date pregnancy test isn't only medical—it's psychological as well. Inaccurate results can induce undue distress, confusion, or early rejoicing.Though home pregnancy tests are an efficient and convenient means of early pregnancy detection, their accuracy relies on a number of major factors, foremost among them their expiration date. Testing with one that has expired may cause emotional distress and delay medical attention at a time when it's needed most.

why its important to check the expiry date on your pregnancy test?

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Human papillomavirus (<span>HPV</span>) is a virus that affects every sexually active person at some point of their life, even if there are no symptoms. The <span>World Health Organization</span> explains that it can affect the skin, genital area, and throat. While preventative measures do help, they cannot totally protect themselves from transmission. Despite the contagious nature of the virus, these infections go away without treatment. However, there are some likely scenarios where they can cause abnormal cells to develop, which later on become cancer. 

What deters many people from getting themselves checked out is the general stigma surrounding sexually transmitted infections or diseases. So, when at home tests became available, the rates screenings improved a lot! 

A new study suggests that women are much more likely to get screened for HPV (human papillomavirus) if they can do the test themselves at home in private. This is a big deal because almost all cervical cancers are caused by HPV. Researchers found that when women were offered a mail-in test kit, the number of women getting screened more than doubled. 

<h2>Why <span rel="noindex">At-Home Testing is a Game-Changer</span> </h2>

Around 11,500 women are diagnosed with cervical cancer each year in the U.S. Sadly, more than half of these women have either rarely or never been screened for HPV. Traditional screening often involves a pelvic exam at a clinic, which can be uncomfortable or distressing for some women. It also requires them to take time off and travel to the clinic. 

The good news is that the first at-home screening test for cervical cancer recently got approved for use in the U.S. and should be available very soon. This new option could make a huge difference in how many women get screened. 

To see how at-home testing would work in real life, researchers studied nearly 2,500 women aged 30 to 65. They divided the women into three groups: 

<ul><li>One group received a phone call reminding them to go to a clinic for screening.</li><li>Another group was mailed an at-home self-collection test kit.</li><li>The third group received an at-home kit and also got a follow-up call if they didn't return their kit quickly.</li></ul>

The results were clear: women who were offered an at-home test kit were more than twice as likely to get screened. About 41% of those who received a kit participated, compared to only 17% who just got a phone reminder to go to a clinic. When women who received a kit also got follow-up reminders, participation jumped even higher, to 47%. Interestingly, over 80% of the women in the test kit groups who participated chose to mail in their kit for analysis, rather than going to a clinic. 

<h2>Making At-Home Tests Accessible </h2>

The study also found that about 13% of the women who returned a kit tested positive for a high-risk type of HPV. As these self-collection tests become more widely available, it's crucial to ensure they are offered in clinics and health centers, especially for people who face bigger challenges in accessing healthcare. By removing these hurdles, experts hope to increase screening rates and significantly reduce the burden of preventable cervical cancer. 

Researchers now plan to investigate how to best use these HPV self-collection tests in different healthcare settings. While at-home HPV testing offers great promise, the next challenge is to make sure it's adopted safely and effectively into regular medical practice. This includes figuring out how healthcare providers can best follow up with women who have abnormal test results. 

world health organization

At-Home HPV Testing4

At-Home HPV Testing Improves Cancer Screenings

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Cancer Screenings study

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Human papillomavirus (HPV) is a virus that affects every sexually active person at some point of their life, even if there are no symptoms. The World Health Organization explains that it can affect the skin, genital area, and throat. While preventative measures do help, they cannot totally protect themselves from transmission. Despite the contagious nature of the virus, these infections go away without treatment. However, there are some likely scenarios where they can cause abnormal cells to develop, which later on become cancer. What deters many people from getting themselves checked out is the general stigma surrounding sexually transmitted infections or diseases. So, when at home tests became available, the rates screenings improved a lot! A new study suggests that women are much more likely to get screened for HPV (human papillomavirus) if they can do the test themselves at home in private. This is a big deal because almost all cervical cancers are caused by HPV. Researchers found that when women were offered a mail-in test kit, the number of women getting screened more than doubled. Why At-Home Testing is a Game-Changer Around 11,500 women are diagnosed with cervical cancer each year in the U.S. Sadly, more than half of these women have either rarely or never been screened for HPV. Traditional screening often involves a pelvic exam at a clinic, which can be uncomfortable or distressing for some women. It also requires them to take time off and travel to the clinic. The good news is that the first at-home screening test for cervical cancer recently got approved for use in the U.S. and should be available very soon. This new option could make a huge difference in how many women get screened. How the Study Proved Its Point To see how at-home testing would work in real life, researchers studied nearly 2,500 women aged 30 to 65. They divided the women into three groups: One group received a phone call reminding them to go to a clinic for screening.Another group was mailed an at-home self-collection test kit.The third group received an at-home kit and also got a follow-up call if they didn't return their kit quickly.The results were clear: women who were offered an at-home test kit were more than twice as likely to get screened. About 41% of those who received a kit participated, compared to only 17% who just got a phone reminder to go to a clinic. When women who received a kit also got follow-up reminders, participation jumped even higher, to 47%. Interestingly, over 80% of the women in the test kit groups who participated chose to mail in their kit for analysis, rather than going to a clinic. Making At-Home Tests Accessible The study also found that about 13% of the women who returned a kit tested positive for a high-risk type of HPV. As these self-collection tests become more widely available, it's crucial to ensure they are offered in clinics and health centers, especially for people who face bigger challenges in accessing healthcare. By removing these hurdles, experts hope to increase screening rates and significantly reduce the burden of preventable cervical cancer. Researchers now plan to investigate how to best use these HPV self-collection tests in different healthcare settings. While at-home HPV testing offers great promise, the next challenge is to make sure it's adopted safely and effectively into regular medical practice. This includes figuring out how healthcare providers can best follow up with women who have abnormal test results. 

at-home hpv testing improves cancer screenings: study

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As per the American Society of Cataract and Refractive Surgery, June is the <span>cataract awareness month</span>. This has been designated as a month to spread awareness around cataract and educate the public about it. This is also the leading cause of <span>vision loss</span> worldwide. This month-long observance also highlights the importance of early detection and treatment of cataracts, and emphasizes that prompt intervention can significantly preserve vision. 

<h4>Why Is It Declared As The <span rel="noindex">Cataract Month</span>?</h4>

As per the International Agency for the Prevention of <span>Blindness</span> (IAPB), this has been done to provide patients and professionals with free educational resources on cataract, which is the clouding of eye's lens. According to the Centers for Disease Control and Prevention (CDC), cataract is the leading cause of blindness worldwide and the leading cause of vision loss in the United States. An estimated 20.5 million Americans aged 40 year and older have cataract in one or both eyes. 

It is the clouding of eye's natural lens, which sits just behind the iris. In a healthy eye, this lens focuses light onto the retina, allowing us to see clearly. Over time, due to aging or other factors, this lens may become cloudy, leading to blurred or dimmed vision. 

As per the World Health Organization (WHO), cataracts account for nearly 51% of world blindness and affects over 65 million people. 

<h4>History Of Cataract Awareness Month </h4>

Prevent Blindness declared the month of June as Cataract Awareness Month and it has been joined by other organizations, including the American Academy of Ophthalmology (AAO), and UNC Ophthalmology. This month spotlights an ocular disease. 

The earliest documented case of cataract was reported to be in a museum in Cairo that houses a small statue from the 5th dynasty. The wooden statue is of a priest reader who has a white patch carved into the pupil of the left eye. It is thought to represent a cataract. 

The earliest procedure of cataract removal is couching. Several illustrations too have been found inside Egyptian temples and tombs depict surgical instruments that indicate the use of couching, a procedure that involved dislodging the eye lens to clear the cataract. 

<h4>How Does Cataract Affect Vision?</h4>

<ul><li>Blurred or foggy vision</li><li>Increased sensitivity to light or glare</li><li>Difficulty seeing at night</li><li>Colors appear faded or yellow</li><li>Frequent changes in glasses prescription</li><li>Seeing halos around lights</li></ul>

Cataract are caused by various factors, some of which include diabetes, prolonged exposure to UV rays, smoking and alcohol consumption, long-term use of corticosteroids, and eye injuries. 

The best way to prevent them is to wear UV-protective sunglasses, manage systemic conditions like diabetes and also go for regular eye exams, especially after the age of 40. It is also important to focus on your diet and other lifestyle habits, and consume more green leafy vegetables, and fruits.

june cataract month

eye health

health and wellness

cataract awareness month

cataract month

vision loss

blindness

As per the American Society of Cataract and Refractive Surgery, June is the cataract awareness month. This has been designated as a month to spread awareness around cataract and educate the public about it. This is also the leading cause of vision loss worldwide. This month-long observance also highlights the importance of early detection and treatment of cataracts, and emphasizes that prompt intervention can significantly preserve vision. Why Is It Declared As The Cataract Month?As per the International Agency for the Prevention of Blindness (IAPB), this has been done to provide patients and professionals with free educational resources on cataract, which is the clouding of eye's lens. According to the Centers for Disease Control and Prevention (CDC), cataract is the leading cause of blindness worldwide and the leading cause of vision loss in the United States. An estimated 20.5 million Americans aged 40 year and older have cataract in one or both eyes. What Is Cataract?It is the clouding of eye's natural lens, which sits just behind the iris. In a healthy eye, this lens focuses light onto the retina, allowing us to see clearly. Over time, due to aging or other factors, this lens may become cloudy, leading to blurred or dimmed vision. As per the World Health Organization (WHO), cataracts account for nearly 51% of world blindness and affects over 65 million people. History Of Cataract Awareness Month Prevent Blindness declared the month of June as Cataract Awareness Month and it has been joined by other organizations, including the American Academy of Ophthalmology (AAO), and UNC Ophthalmology. This month spotlights an ocular disease. The earliest documented case of cataract was reported to be in a museum in Cairo that houses a small statue from the 5th dynasty. The wooden statue is of a priest reader who has a white patch carved into the pupil of the left eye. It is thought to represent a cataract. The earliest procedure of cataract removal is couching. Several illustrations too have been found inside Egyptian temples and tombs depict surgical instruments that indicate the use of couching, a procedure that involved dislodging the eye lens to clear the cataract. How Does Cataract Affect Vision?The following symptoms are:Blurred or foggy visionIncreased sensitivity to light or glareDifficulty seeing at nightColors appear faded or yellowFrequent changes in glasses prescriptionSeeing halos around lightsWhat Causes Cataract?Cataract are caused by various factors, some of which include diabetes, prolonged exposure to UV rays, smoking and alcohol consumption, long-term use of corticosteroids, and eye injuries. The best way to prevent them is to wear UV-protective sunglasses, manage systemic conditions like diabetes and also go for regular eye exams, especially after the age of 40. It is also important to focus on your diet and other lifestyle habits, and consume more green leafy vegetables, and fruits.

cataract awareness month: importance, significance, and history

Is Regrowing Human Limbs A Possibility Now?

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Nature is filled with amazing flora and fauna, all with different sets of abilities and unique features. While considered impossible for humans, there are many animals that can <span>regenerate</span> part of their bodies. Sea creatures like starfish and octopuses can regenerate their limbs in case they get hurt or have to decapitate themselves to escape from a difficult situation. Living in the wild, these creatures evolved to adapt to the harsh nature of their surroundings. 

This is not the case for humans. Many people have to live without their limbs or organs, whether it is due to being born that way or being hurt/experiencing an accident. However, taking inspiration from one such animal, researchers are looking into human limb regeneration. 

Axolotls, with their unique smiles and frilly gills, have become very popular. But these friendly salamanders are more than just cute faces. Scientists are studying them because they might help us solve a big medical mystery: Can people someday grow back lost body parts, like an arm or a leg? 

<h2>Why Did Researchers Pick Axolotls? </h2>

In a groundbreaking <span>study</span> published on June 10 in Nature Communications, Monaghan's team utilized genetically engineered axolotls that glow in the dark to better understand this astonishing process. What makes axolotls so special? They have an incredible ability to regrow any part of their body, no matter how old they are. If they lose a leg, they can grow it right back. 

Even if their heart, lungs, or brain gets hurt, they can fix themselves! This amazing ability makes them champions among animals for their extreme healing powers. One of the long-standing questions in limb regrowth has been how cells "know" precisely which part of the limb to rebuild. For instance, if an axolotl loses its upper arm, it regenerates the entire arm. However, if the injury occurs further down the limb, only the lower arm and hand regrow. 

The key to this mystery appears to be a small molecule called retinoic acid, a compound related to vitamin A and commonly found in skincare products under the name retinol. This molecule acts like a GPS, providing cells with crucial positional information, guiding them on where they are on the body and what specific part needs to be rebuilt. 

<h2>How Retinoic Acid Directs Regrowth </h2>

The study's findings were compelling. When axolotls were given a drug that prevented the breakdown of retinoic acid, their limbs regenerated incorrectly, with an upper arm forming where a lower arm should have been. In contrast, axolotls not given the drug regrew their limbs normally. This strongly suggests that retinoic acid precisely instructs cells about their location and what structure to grow. 

While we are still a long way from growing human limbs, this study is a big step in that direction. The scientists believe this research could eventually help people. We all have the same basic genetic instructions for building limbs that we used when we were developing as babies. The challenge now is to figure out how to turn those same instructions back on later in life, which axolotls can do but humans can't yet. This is one of the oldest and most exciting questions in biology. Thanks to the growing interest in axolotls, especially among kids, these unique animals are helping to advance amazing scientific discoveries. It's quite surprising how popular axolotls have become, showing up everywhere from airports to toy stores. 

Regrowing Human Limbs

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can human limbs regenerate

Study

Nature is filled with amazing flora and fauna, all with different sets of abilities and unique features. While considered impossible for humans, there are many animals that can regenerate part of their bodies. Sea creatures like starfish and octopuses can regenerate their limbs in case they get hurt or have to decapitate themselves to escape from a difficult situation. Living in the wild, these creatures evolved to adapt to the harsh nature of their surroundings. This is not the case for humans. Many people have to live without their limbs or organs, whether it is due to being born that way or being hurt/experiencing an accident. However, taking inspiration from one such animal, researchers are looking into human limb regeneration. Axolotls, with their unique smiles and frilly gills, have become very popular. But these friendly salamanders are more than just cute faces. Scientists are studying them because they might help us solve a big medical mystery: Can people someday grow back lost body parts, like an arm or a leg? Why Did Researchers Pick Axolotls? In a groundbreaking study published on June 10 in Nature Communications, Monaghan's team utilized genetically engineered axolotls that glow in the dark to better understand this astonishing process. What makes axolotls so special? They have an incredible ability to regrow any part of their body, no matter how old they are. If they lose a leg, they can grow it right back. Even if their heart, lungs, or brain gets hurt, they can fix themselves! This amazing ability makes them champions among animals for their extreme healing powers. One of the long-standing questions in limb regrowth has been how cells "know" precisely which part of the limb to rebuild. For instance, if an axolotl loses its upper arm, it regenerates the entire arm. However, if the injury occurs further down the limb, only the lower arm and hand regrow. Body's Internal GPS The key to this mystery appears to be a small molecule called retinoic acid, a compound related to vitamin A and commonly found in skincare products under the name retinol. This molecule acts like a GPS, providing cells with crucial positional information, guiding them on where they are on the body and what specific part needs to be rebuilt. How Retinoic Acid Directs Regrowth The study's findings were compelling. When axolotls were given a drug that prevented the breakdown of retinoic acid, their limbs regenerated incorrectly, with an upper arm forming where a lower arm should have been. In contrast, axolotls not given the drug regrew their limbs normally. This strongly suggests that retinoic acid precisely instructs cells about their location and what structure to grow. Hope for Human Healing While we are still a long way from growing human limbs, this study is a big step in that direction. The scientists believe this research could eventually help people. We all have the same basic genetic instructions for building limbs that we used when we were developing as babies. The challenge now is to figure out how to turn those same instructions back on later in life, which axolotls can do but humans can't yet. This is one of the oldest and most exciting questions in biology. Thanks to the growing interest in axolotls, especially among kids, these unique animals are helping to advance amazing scientific discoveries. It's quite surprising how popular axolotls have become, showing up everywhere from airports to toy stores. 

is regrowing human limbs a possibility now? sea salamanders study could be the medical future

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